NP-MRD: Showing NP-Card for 5-hydroxy-2-(hydroxymethyl)-9-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-8h,11h-oxepino[2,3-h]chromen-4-one (NP0210852)

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Record Information

Version

2.0

Created at

2022-09-05 08:51:23 UTC

Updated at

2022-09-05 08:51:23 UTC

NP-MRD ID

NP0210852

Secondary Accession Numbers

None

Natural Product Identification

Common Name

5-hydroxy-2-(hydroxymethyl)-9-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-8h,11h-oxepino[2,3-h]chromen-4-one

Description

5-Hydroxy-2-(hydroxymethyl)-9-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-4H,8H,11H-oxepino[2,3-h]chromen-4-one belongs to the class of organic compounds known as o-glycosyl compounds. These are glycoside in which a sugar group is bonded through one carbon to another group via a O-glycosidic bond. 5-hydroxy-2-(hydroxymethyl)-9-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-8h,11h-oxepino[2,3-h]chromen-4-one is found in Eranthis hyemalis. Based on a literature review very few articles have been published on 5-hydroxy-2-(hydroxymethyl)-9-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-4H,8H,11H-oxepino[2,3-h]chromen-4-one.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309052210512D          

 32 35  0  0  1  0            999 V2000
   -0.4647   -0.7401    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0328   -1.4430    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4256   -2.1685    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0063   -2.8714    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3865   -3.5969    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2112   -3.6195    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8310   -2.8489    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.2238   -2.1234    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0485   -2.1008    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4413   -1.3754    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0094   -0.6724    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1847   -0.6950    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7528    0.0079    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7919   -1.4205    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2534   -1.2302    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.8733   -1.7746    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8342   -2.5986    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5596   -2.9914    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2626   -2.5596    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.9880   -2.9524    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.6910   -2.5205    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.4164   -2.9133    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    8.1194   -2.4814    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.0968   -1.6567    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.4390   -3.7380    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    8.1645   -4.1308    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.7361   -4.1699    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.7586   -4.9946    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.0106   -3.7771    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.3077   -4.2089    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.1655   -3.0818    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3708   -2.8603    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  4  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  2  0  0  0  0
  9 10  1  0  0  0  0
 10 11  2  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 12 14  2  0  0  0  0
  2 14  1  0  0  0  0
  8 14  1  0  0  0  0
 10 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 20 19  1  6  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  6  0  0  0
 23 24  1  0  0  0  0
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 25 27  1  0  0  0  0
 27 28  1  6  0  0  0
 27 29  1  0  0  0  0
 20 29  1  0  0  0  0
 29 30  1  1  0  0  0
 17 31  2  0  0  0  0
 31 32  1  0  0  0  0
  9 32  1  0  0  0  0
M  END

     RDKit          3D

 56 59  0  0  0  0  0  0  0  0999 V2000
    4.8730   -1.2607   -1.6716 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.3630   -0.4215   -0.9179 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0329    0.0354    0.2218 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4749    0.9656    1.0627 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2134    1.4333    2.2702 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4495    0.8174    2.3819 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.2891    1.4024    0.7464 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6017    1.0131   -0.3146 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3391    1.5467   -0.5580 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5692    1.1886   -1.6397 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0840    0.2605   -2.5109 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3616   -0.3065   -2.3018 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8369   -1.2221   -3.1863 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.1063    0.0748   -1.2078 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7128    1.6332   -2.0194 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4187    2.6863   -1.3958 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4971    2.4796    0.0877 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8320    2.3447    0.6831 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5806    1.2958    0.2163 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0332    0.0536    0.4045 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.9184   -0.6913   -0.7694 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0238   -1.7259   -0.5029 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.5482   -2.3952   -1.7745 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7013   -2.9018   -2.4035 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6139   -2.7110    0.4583 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.6307   -3.6470    0.7756 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9713   -1.9813    1.7347 C   0  0  2  0  0  0  0  0  0  0  0  0
   -3.5779   -2.8092    2.6495 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8804   -0.8051    1.3537 C   0  0  1  0  0  0  0  0  0  0  0  0
   -4.2671   -0.1020    2.4687 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4230    2.4145    0.8742 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0325    2.5194    0.5332 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0128   -0.3780    0.4117 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3814    2.5300    2.2613 H   0  0  0  0  0  0  0  0  0  0  0  0
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    6.6978    0.8525    3.3566 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5136   -0.0485   -3.3722 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.6079   -1.7623   -3.3306 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9828    3.6852   -1.6459 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4617    2.6460   -1.7946 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4177    3.2790    0.4902 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7156    2.2170    1.7816 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0370    0.1339    0.9237 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1284   -1.2584   -0.0279 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0493   -1.7021   -2.4531 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8356   -3.2048   -1.5188 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4754   -2.9494   -3.3842 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4995   -3.1746   -0.0152 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4906   -4.3250    0.0934 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0351   -1.5234    2.1154 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4385   -3.7541    2.3581 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7045   -1.2245    0.7685 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8348   -0.5196    3.2623 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6651    2.2605    1.9252 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6247    2.2697    1.4365 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2996    3.5596    0.2110 H   0  0  0  0  0  0  0  0  0  0  0  0
 24 23  1  0
 23 22  1  0
 22 21  1  0
 21 20  1  0
 20 19  1  0
 19 18  1  0
 18 17  1  0
 17 31  2  0
 31 32  1  0
 32  9  1  0
  9  8  2  0
  8  7  1  0
  7  4  1  0
  4  5  1  0
  5  6  1  0
  4  3  2  0
  3  2  1  0
  2  1  2  0
  2 14  1  0
 14 12  2  0
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 12 11  1  0
 11 10  2  0
 10 15  1  0
 15 16  1  0
 20 29  1  0
 29 30  1  0
 29 27  1  0
 27 28  1  0
 27 25  1  0
 25 26  1  0
 25 22  1  0
 16 17  1  0
 10  9  1  0
 14  8  1  0
 24 47  1  0
 23 45  1  0
 23 46  1  0
 22 44  1  1
 20 43  1  1
 18 41  1  0
 18 42  1  0
 31 54  1  0
 32 55  1  0
 32 56  1  0
  5 34  1  0
  5 35  1  0
  6 36  1  0
  3 33  1  0
 13 38  1  0
 11 37  1  0
 16 39  1  0
 16 40  1  0
 29 52  1  6
 30 53  1  0
 27 50  1  1
 28 51  1  0
 25 48  1  6
 26 49  1  0
M  END


  Mrv1652309052210512D          

 32 35  0  0  1  0            999 V2000
   -0.4647   -0.7401    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0328   -1.4430    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4256   -2.1685    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0063   -2.8714    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3865   -3.5969    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2112   -3.6195    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8310   -2.8489    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.2238   -2.1234    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0485   -2.1008    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4413   -1.3754    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0094   -0.6724    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1847   -0.6950    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7528    0.0079    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7919   -1.4205    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2534   -1.2302    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.8733   -1.7746    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8342   -2.5986    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5596   -2.9914    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2626   -2.5596    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.9880   -2.9524    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.6910   -2.5205    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.4164   -2.9133    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    8.1194   -2.4814    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.0968   -1.6567    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.4390   -3.7380    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    8.1645   -4.1308    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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    6.7586   -4.9946    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.0106   -3.7771    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.3077   -4.2089    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.1655   -3.0818    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3708   -2.8603    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  4  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  2  0  0  0  0
  9 10  1  0  0  0  0
 10 11  2  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 12 14  2  0  0  0  0
  2 14  1  0  0  0  0
  8 14  1  0  0  0  0
 10 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 20 19  1  6  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  6  0  0  0
 23 24  1  0  0  0  0
 22 25  1  0  0  0  0
 25 26  1  1  0  0  0
 25 27  1  0  0  0  0
 27 28  1  6  0  0  0
 27 29  1  0  0  0  0
 20 29  1  0  0  0  0
 29 30  1  1  0  0  0
 17 31  2  0  0  0  0
 31 32  1  0  0  0  0
  9 32  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0210852

> <DATABASE_NAME>
NP-MRD

> <SMILES>
OC[C@H]1O[C@@H](OCC2=CCC3=C4OC(CO)=CC(=O)C4=C(O)C=C3OC2)[C@H](O)[C@@H](O)[C@@H]1O

> <INCHI_IDENTIFIER>
InChI=1S/C21H24O11/c22-5-10-3-12(24)16-13(25)4-14-11(20(16)31-10)2-1-9(7-29-14)8-30-21-19(28)18(27)17(26)15(6-23)32-21/h1,3-4,15,17-19,21-23,25-28H,2,5-8H2/t15-,17-,18+,19-,21-/m1/s1

> <INCHI_KEY>
KXDYPPVOPZKXMX-PEVLUNPASA-N

> <FORMULA>
C21H24O11

> <MOLECULAR_WEIGHT>
452.412

> <EXACT_MASS>
452.131861593

> <JCHEM_ACCEPTOR_COUNT>
11

> <JCHEM_ATOM_COUNT>
56

> <JCHEM_AVERAGE_POLARIZABILITY>
44.68417928480233

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
6

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
5-hydroxy-2-(hydroxymethyl)-9-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-4H,8H,11H-oxepino[2,3-h]chromen-4-one

> <JCHEM_LOGP>
-1.071827175666666

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
12.204808743397136

> <JCHEM_PKA_STRONGEST_ACIDIC>
7.33182565366653

> <JCHEM_PKA_STRONGEST_BASIC>
-2.9810835523425023

> <JCHEM_POLAR_SURFACE_AREA>
175.37

> <JCHEM_REFRACTIVITY>
109.03920000000004

> <JCHEM_ROTATABLE_BOND_COUNT>
5

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
5-hydroxy-2-(hydroxymethyl)-9-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-8H,11H-oxepino[2,3-h]chromen-4-one

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 05-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   05-SEP-22         0                                  
HETATM    1  O   UNK     0      -0.867  -1.382   0.000  0.00  0.00           O+0
HETATM    2  C   UNK     0      -0.061  -2.694   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -0.794  -4.048   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       0.012  -5.360   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -0.722  -6.714   0.000  0.00  0.00           C+0
HETATM    6  O   UNK     0      -2.261  -6.756   0.000  0.00  0.00           O+0
HETATM    7  O   UNK     0       1.551  -5.318   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0       2.284  -3.964   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       3.824  -3.922   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       4.557  -2.567   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       3.751  -1.255   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       2.211  -1.297   0.000  0.00  0.00           C+0
HETATM   13  O   UNK     0       1.405   0.015   0.000  0.00  0.00           O+0
HETATM   14  C   UNK     0       1.478  -2.652   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0       6.073  -2.296   0.000  0.00  0.00           O+0
HETATM   16  C   UNK     0       7.230  -3.312   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       7.157  -4.851   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       8.511  -5.584   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0       9.823  -4.778   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0      11.178  -5.511   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0      12.490  -4.705   0.000  0.00  0.00           O+0
HETATM   22  C   UNK     0      13.844  -5.438   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      15.156  -4.632   0.000  0.00  0.00           C+0
HETATM   24  O   UNK     0      15.114  -3.093   0.000  0.00  0.00           O+0
HETATM   25  C   UNK     0      13.886  -6.978   0.000  0.00  0.00           C+0
HETATM   26  O   UNK     0      15.240  -7.711   0.000  0.00  0.00           O+0
HETATM   27  C   UNK     0      12.574  -7.784   0.000  0.00  0.00           C+0
HETATM   28  O   UNK     0      12.616  -9.323   0.000  0.00  0.00           O+0
HETATM   29  C   UNK     0      11.220  -7.051   0.000  0.00  0.00           C+0
HETATM   30  O   UNK     0       9.908  -7.857   0.000  0.00  0.00           O+0
HETATM   31  C   UNK     0       5.909  -5.753   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       4.425  -5.339   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3   14                                                  
CONECT    3    2    4                                                       
CONECT    4    3    5    7                                                  
CONECT    5    4    6                                                       
CONECT    6    5                                                            
CONECT    7    4    8                                                       
CONECT    8    7    9   14                                                  
CONECT    9    8   10   32                                                  
CONECT   10    9   11   15                                                  
CONECT   11   10   12                                                       
CONECT   12   11   13   14                                                  
CONECT   13   12                                                            
CONECT   14   12    2    8                                                  
CONECT   15   10   16                                                       
CONECT   16   15   17                                                       
CONECT   17   16   18   31                                                  
CONECT   18   17   19                                                       
CONECT   19   18   20                                                       
CONECT   20   19   21   29                                                  
CONECT   21   20   22                                                       
CONECT   22   21   23   25                                                  
CONECT   23   22   24                                                       
CONECT   24   23                                                            
CONECT   25   22   26   27                                                  
CONECT   26   25                                                            
CONECT   27   25   28   29                                                  
CONECT   28   27                                                            
CONECT   29   27   20   30                                                  
CONECT   30   29                                                            
CONECT   31   17   32                                                       
CONECT   32   31    9                                                       
MASTER        0    0    0    0    0    0    0    0   32    0   70    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₁H₂₄O₁₁

Average Mass

452.4120 Da

Monoisotopic Mass

452.13186 Da

IUPAC Name

5-hydroxy-2-(hydroxymethyl)-9-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-4H,8H,11H-oxepino[2,3-h]chromen-4-one

Traditional Name

5-hydroxy-2-(hydroxymethyl)-9-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-8H,11H-oxepino[2,3-h]chromen-4-one

CAS Registry Number

Not Available

SMILES

OC[C@H]1O[C@@H](OCC2=CCC3=C4OC(CO)=CC(=O)C4=C(O)C=C3OC2)[C@H](O)[C@@H](O)[C@@H]1O

InChI Identifier

InChI=1S/C21H24O11/c22-5-10-3-12(24)16-13(25)4-14-11(20(16)31-10)2-1-9(7-29-14)8-30-21-19(28)18(27)17(26)15(6-23)32-21/h1,3-4,15,17-19,21-23,25-28H,2,5-8H2/t15-,17-,18+,19-,21-/m1/s1

InChI Key

KXDYPPVOPZKXMX-PEVLUNPASA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Eranthis hyemalis	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as o-glycosyl compounds. These are glycoside in which a sugar group is bonded through one carbon to another group via a O-glycosidic bond.

Kingdom

Organic compounds

Super Class

Organic oxygen compounds

Class

Organooxygen compounds

Sub Class

Carbohydrates and carbohydrate conjugates

Direct Parent

O-glycosyl compounds

Alternative Parents

Substituents

Hexose monosaccharide
Benzoxepine
Chromone
O-glycosyl compound
Benzopyran
1-benzopyran
1-hydroxy-2-unsubstituted benzenoid
Alkyl aryl ether
Pyranone
Monosaccharide
Oxane
Benzenoid
Pyran
Vinylogous acid
Heteroaromatic compound
Secondary alcohol
Polyol
Acetal
Organoheterocyclic compound
Ether
Oxacycle
Primary alcohol
Alcohol
Hydrocarbon derivative
Organic oxide
Aromatic alcohol
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	-1.1	ChemAxon
pKa (Strongest Acidic)	7.33	ChemAxon
pKa (Strongest Basic)	-3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	11	ChemAxon
Hydrogen Donor Count	6	ChemAxon
Polar Surface Area	175.37 Å²	ChemAxon
Rotatable Bond Count	5	ChemAxon
Refractivity	109.04 m³·mol⁻¹	ChemAxon
Polarizability	44.68 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

10239002

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

14034916

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 5-hydroxy-2-(hydroxymethyl)-9-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-8h,11h-oxepino[2,3-h]chromen-4-one (NP0210852)

MOL for NP0210852 (5-hydroxy-2-(hydroxymethyl)-9-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-8h,11h-oxepino[2,3-h]chromen-4-one)

3D MOL for NP0210852 (5-hydroxy-2-(hydroxymethyl)-9-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-8h,11h-oxepino[2,3-h]chromen-4-one)

3D SDF for NP0210852 (5-hydroxy-2-(hydroxymethyl)-9-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-8h,11h-oxepino[2,3-h]chromen-4-one)

3D-SDF for NP0210852 (5-hydroxy-2-(hydroxymethyl)-9-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-8h,11h-oxepino[2,3-h]chromen-4-one)

PDB for NP0210852 (5-hydroxy-2-(hydroxymethyl)-9-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-8h,11h-oxepino[2,3-h]chromen-4-one)

3D PDB for NP0210852 (5-hydroxy-2-(hydroxymethyl)-9-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-8h,11h-oxepino[2,3-h]chromen-4-one)

SMILES for NP0210852 (5-hydroxy-2-(hydroxymethyl)-9-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-8h,11h-oxepino[2,3-h]chromen-4-one)

INCHI for NP0210852 (5-hydroxy-2-(hydroxymethyl)-9-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-8h,11h-oxepino[2,3-h]chromen-4-one)

Structure for NP0210852 (5-hydroxy-2-(hydroxymethyl)-9-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-8h,11h-oxepino[2,3-h]chromen-4-one)

3D Structure for NP0210852 (5-hydroxy-2-(hydroxymethyl)-9-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-8h,11h-oxepino[2,3-h]chromen-4-one)