NP-MRD: Showing NP-Card for (2r)-2-[(1r,2r,10r,11s,13s,14s,16r)-13-(acetyloxy)-10,14-dimethyl-7-oxo-15,19-dioxapentacyclo[14.2.1.0¹,¹⁴.0²,¹¹.0⁵,¹⁰]nonadeca-5,8-dien-16-yl]-6-methylheptan-3-yl acetate (NP0209698)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-05 07:12:36 UTC

Updated at

2022-09-05 07:12:37 UTC

NP-MRD ID

NP0209698

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(2r)-2-[(1r,2r,10r,11s,13s,14s,16r)-13-(acetyloxy)-10,14-dimethyl-7-oxo-15,19-dioxapentacyclo[14.2.1.0¹,¹⁴.0²,¹¹.0⁵,¹⁰]nonadeca-5,8-dien-16-yl]-6-methylheptan-3-yl acetate

Description

Isogosterone D belongs to the class of organic compounds known as 3-oxo delta-1,4-steroids. These are 3-oxo steroids containing a double bond between positions 1 and 2, as well as positions 4 and 5. Based on a literature review very few articles have been published on isogosterone D.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309052209122D          

 38 42  0  0  1  0            999 V2000
    1.8055   -2.5724    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9805   -2.5724    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5680   -3.2869    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5680   -1.8580    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.9805   -1.1435    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8055   -1.1435    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2180   -1.8580    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0430   -1.8580    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4555   -2.5724    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4555   -1.1435    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5680   -0.4290    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.9805    0.2855    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2570   -0.4290    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.1622   -1.2030    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0304   -1.2729    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3817   -0.2133    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.1860   -0.7728    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2029   -0.0768    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.6816   -0.7487    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5028   -0.6702    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8454    0.0803    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6667    0.1589    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.0093    0.9094    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8305    0.9880    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5306    1.5814    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7093    1.5028    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3668    0.7523    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.8881    1.4242    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5455    0.6737    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.0733    1.3745    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2547    1.3330    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.7742    2.0036    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1148    2.7551    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9358    2.8358    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6343    3.4257    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9450    0.5534    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.4103    1.1817    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1579    0.3795    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  2  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  8 10  1  0  0  0  0
  5 11  1  0  0  0  0
 11 12  1  6  0  0  0
 13 11  1  6  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  6  0  0  0
 13 17  1  0  0  0  0
 16 18  1  0  0  0  0
 18 19  1  6  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  2  0  0  0  0
 22 23  1  0  0  0  0
 23 24  2  0  0  0  0
 23 25  1  0  0  0  0
 25 26  2  0  0  0  0
 26 27  1  0  0  0  0
 21 27  1  0  0  0  0
 27 28  1  1  0  0  0
 27 29  1  0  0  0  0
 18 29  1  0  0  0  0
 29 30  1  1  0  0  0
 30 31  1  0  0  0  0
 31 32  1  6  0  0  0
 32 33  1  0  0  0  0
 33 34  1  0  0  0  0
 33 35  2  0  0  0  0
 31 36  1  0  0  0  0
 16 36  1  0  0  0  0
 36 37  1  1  0  0  0
 36 38  1  0  0  0  0
 13 38  1  0  0  0  0
M  END

     RDKit          3D

 82 86  0  0  0  0  0  0  0  0999 V2000
    5.9630    2.2577   -0.1631 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7110    1.4454   -0.3153 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1716    1.5210   -1.4430 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.1876    0.6828    0.6772 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.9835   -0.1216    0.5556 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.2490   -1.4459    1.0780 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3370   -2.2281    0.4320 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2307   -2.6846   -0.9562 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5364   -3.5266   -1.2392 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3113   -1.6326   -2.0264 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9606    0.7251    1.2925 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.8452    2.0387    0.5519 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6583    0.2137    1.6481 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.4825   -0.8960    2.6020 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7578   -1.6212    2.0443 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2682   -0.5449    1.1595 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.0731   -0.2147    0.4786 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3687   -0.9307    0.2303 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.2434   -2.3072   -0.3045 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3790   -2.6764   -1.2257 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6725   -1.5357   -2.1564 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8557   -1.8062   -3.4066 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1461   -0.7690   -4.4148 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3207   -1.0587   -5.6201 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2139    0.5955   -3.9148 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0232    0.8225   -2.6498 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7401   -0.1545   -1.6300 C   0  0  1  0  0  0  0  0  0  0  0  0
   -4.9200   -0.1314   -0.6527 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4353    0.0688   -0.8914 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.1308    1.4517   -0.4900 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2349    1.7506    0.9859 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.7072    3.0446    1.2007 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4228    4.0851    1.7253 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8646    5.4506    1.9515 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6398    3.8532    2.0335 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5282    0.7300    1.8573 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.2852    0.5703    3.1426 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2272    1.2465    2.0658 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.0775    2.4204    0.9412 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.8142    1.6082   -0.4604 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.9140    3.2075   -0.7075 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.6767   -0.0901   -0.4832 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.4887   -1.4677    2.1852 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.3055   -2.1029    1.0136 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.2985   -1.5959    0.4842 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.6485   -3.0998    1.1203 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.4146   -3.3965   -1.1249 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.4910   -3.7446   -2.3123 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.3936   -2.8528   -1.0560 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.5221   -4.4315   -0.6336 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.1292   -0.9341   -1.7999 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3568   -1.1832   -2.3269 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.6703   -2.1200   -3.0061 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.4616    1.0464    2.2862 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.9618    2.6311    0.9309 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.7690    2.6468    0.5969 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6230    1.8347   -0.5107 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2671   -1.5785    2.8312 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1347   -0.4928    3.6186 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4246   -1.9898    2.8073 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3723   -2.4775    1.4275 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3113   -0.8518    0.8063 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2818   -2.3719   -0.8794 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1735   -3.0689    0.4879 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1227   -3.5985   -1.7764 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3084   -2.8702   -0.6625 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8086   -2.8238   -3.8065 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4292    1.4168   -4.6338 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1050    1.8858   -2.3584 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9268    0.7163    0.0178 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8319    0.0002   -1.3112 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.0810   -1.0633   -0.1267 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6417   -0.2678   -1.6272 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7468    2.2083   -0.9999 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0664    1.7233   -0.7844 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2886    1.7997    1.3254 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1468    5.6317    1.1137 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6809    6.1889    1.8139 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3368    5.5446    2.9047 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5910   -0.4694    3.3465 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7056    0.9537    4.0046 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2061    1.2111    3.1114 H   0  0  0  0  0  0  0  0  0  0  0  0
  9  8  1  0
  8 10  1  0
  8  7  1  0
  7  6  1  0
  6  5  1  0
  5  4  1  0
  4  2  1  0
  2  1  1  0
  2  3  2  0
  5 11  1  0
 11 12  1  0
 11 13  1  0
 13 14  1  0
 14 15  1  0
 16 15  1  1
 16 17  1  0
 16 18  1  0
 18 19  1  0
 19 20  1  0
 20 21  1  0
 21 22  2  0
 22 23  1  0
 23 24  2  0
 23 25  1  0
 25 26  2  0
 26 27  1  0
 27 28  1  1
 27 29  1  0
 29 30  1  0
 30 31  1  0
 31 32  1  0
 32 33  1  0
 33 34  1  0
 33 35  2  0
 31 36  1  0
 36 37  1  1
 36 38  1  0
 17 13  1  0
 29 18  1  0
 13 38  1  1
 36 16  1  0
 27 21  1  0
  9 48  1  0
  9 49  1  0
  9 50  1  0
  8 47  1  0
 10 51  1  0
 10 52  1  0
 10 53  1  0
  7 45  1  0
  7 46  1  0
  6 43  1  0
  6 44  1  0
  5 42  1  6
  1 39  1  0
  1 40  1  0
  1 41  1  0
 11 54  1  1
 12 55  1  0
 12 56  1  0
 12 57  1  0
 14 58  1  0
 14 59  1  0
 15 60  1  0
 15 61  1  0
 18 62  1  1
 19 63  1  0
 19 64  1  0
 20 65  1  0
 20 66  1  0
 22 67  1  0
 25 68  1  0
 26 69  1  0
 28 70  1  0
 28 71  1  0
 28 72  1  0
 29 73  1  6
 30 74  1  0
 30 75  1  0
 31 76  1  1
 34 77  1  0
 34 78  1  0
 34 79  1  0
 37 80  1  0
 37 81  1  0
 37 82  1  0
M  END


  Mrv1652309052209122D          

 38 42  0  0  1  0            999 V2000
    1.8055   -2.5724    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9805   -2.5724    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5680   -3.2869    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5680   -1.8580    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.9805   -1.1435    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8055   -1.1435    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2180   -1.8580    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0430   -1.8580    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4555   -2.5724    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4555   -1.1435    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5680   -0.4290    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.9805    0.2855    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2570   -0.4290    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.1622   -1.2030    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0304   -1.2729    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3817   -0.2133    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.1860   -0.7728    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2029   -0.0768    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.6816   -0.7487    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5028   -0.6702    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8454    0.0803    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6667    0.1589    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.0093    0.9094    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8305    0.9880    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5306    1.5814    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7093    1.5028    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3668    0.7523    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.8881    1.4242    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5455    0.6737    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.0733    1.3745    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2547    1.3330    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.7742    2.0036    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1148    2.7551    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9358    2.8358    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6343    3.4257    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9450    0.5534    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.4103    1.1817    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1579    0.3795    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  2  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  8 10  1  0  0  0  0
  5 11  1  0  0  0  0
 11 12  1  6  0  0  0
 13 11  1  6  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  6  0  0  0
 13 17  1  0  0  0  0
 16 18  1  0  0  0  0
 18 19  1  6  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  2  0  0  0  0
 22 23  1  0  0  0  0
 23 24  2  0  0  0  0
 23 25  1  0  0  0  0
 25 26  2  0  0  0  0
 26 27  1  0  0  0  0
 21 27  1  0  0  0  0
 27 28  1  1  0  0  0
 27 29  1  0  0  0  0
 18 29  1  0  0  0  0
 29 30  1  1  0  0  0
 30 31  1  0  0  0  0
 31 32  1  6  0  0  0
 32 33  1  0  0  0  0
 33 34  1  0  0  0  0
 33 35  2  0  0  0  0
 31 36  1  0  0  0  0
 16 36  1  0  0  0  0
 36 37  1  1  0  0  0
 36 38  1  0  0  0  0
 13 38  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0209698

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(C)CCC(OC(C)=O)[C@@H](C)[C@]12CC[C@@]3(O1)[C@@H]1CCC4=CC(=O)C=C[C@]4(C)[C@H]1C[C@H](OC(C)=O)[C@]3(C)O2

> <INCHI_IDENTIFIER>
InChI=1S/C31H44O7/c1-18(2)8-11-26(35-20(4)32)19(3)31-15-14-30(38-31)24-10-9-22-16-23(34)12-13-28(22,6)25(24)17-27(36-21(5)33)29(30,7)37-31/h12-13,16,18-19,24-27H,8-11,14-15,17H2,1-7H3/t19-,24-,25+,26?,27+,28+,29+,30-,31+/m1/s1

> <INCHI_KEY>
VZAQLESCSMZQIM-PZKLDJMMSA-N

> <FORMULA>
C31H44O7

> <MOLECULAR_WEIGHT>
528.686

> <EXACT_MASS>
528.308703757

> <JCHEM_ACCEPTOR_COUNT>
5

> <JCHEM_ATOM_COUNT>
82

> <JCHEM_AVERAGE_POLARIZABILITY>
57.59251740367644

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2R)-2-[(1R,2R,10R,11S,13S,14S,16R)-13-(acetyloxy)-10,14-dimethyl-7-oxo-15,19-dioxapentacyclo[14.2.1.0^{1,14}.0^{2,11}.0^{5,10}]nonadeca-5,8-dien-16-yl]-6-methylheptan-3-yl acetate

> <JCHEM_LOGP>
5.28876989933333

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_ACIDIC>
18.47315162480147

> <JCHEM_PKA_STRONGEST_BASIC>
-4.0576550649557435

> <JCHEM_POLAR_SURFACE_AREA>
88.13000000000001

> <JCHEM_REFRACTIVITY>
142.87349999999998

> <JCHEM_ROTATABLE_BOND_COUNT>
9

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
(2R)-2-[(1R,2R,10R,11S,13S,14S,16R)-13-(acetyloxy)-10,14-dimethyl-7-oxo-15,19-dioxapentacyclo[14.2.1.0^{1,14}.0^{2,11}.0^{5,10}]nonadeca-5,8-dien-16-yl]-6-methylheptan-3-yl acetate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 05-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   05-SEP-22         0                                  
HETATM    1  C   UNK     0       3.370  -4.802   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       1.830  -4.802   0.000  0.00  0.00           C+0
HETATM    3  O   UNK     0       1.060  -6.136   0.000  0.00  0.00           O+0
HETATM    4  O   UNK     0       1.060  -3.468   0.000  0.00  0.00           O+0
HETATM    5  C   UNK     0       1.830  -2.134   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       3.370  -2.134   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       4.140  -3.468   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       5.680  -3.468   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       6.450  -4.802   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       6.450  -2.134   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       1.060  -0.801   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       1.830   0.533   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      -0.480  -0.801   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0      -0.303  -2.246   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0      -1.923  -2.376   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0      -2.579  -0.398   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0      -2.214  -1.443   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0      -4.112  -0.143   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      -5.006  -1.398   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      -6.539  -1.251   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      -7.178   0.150   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      -8.711   0.297   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      -9.351   1.698   0.000  0.00  0.00           C+0
HETATM   24  O   UNK     0     -10.884   1.844   0.000  0.00  0.00           O+0
HETATM   25  C   UNK     0      -8.457   2.952   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0      -6.924   2.805   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0      -6.285   1.404   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0      -5.391   2.659   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0      -4.752   1.258   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0      -3.870   2.566   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0      -2.342   2.488   0.000  0.00  0.00           C+0
HETATM   32  O   UNK     0      -1.445   3.740   0.000  0.00  0.00           O+0
HETATM   33  C   UNK     0      -2.081   5.143   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0      -3.614   5.294   0.000  0.00  0.00           C+0
HETATM   35  O   UNK     0      -1.184   6.395   0.000  0.00  0.00           O+0
HETATM   36  C   UNK     0      -1.764   1.033   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0      -0.766   2.206   0.000  0.00  0.00           C+0
HETATM   38  O   UNK     0      -0.295   0.708   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3    4                                                  
CONECT    3    2                                                            
CONECT    4    2    5                                                       
CONECT    5    4    6   11                                                  
CONECT    6    5    7                                                       
CONECT    7    6    8                                                       
CONECT    8    7    9   10                                                  
CONECT    9    8                                                            
CONECT   10    8                                                            
CONECT   11    5   12   13                                                  
CONECT   12   11                                                            
CONECT   13   11   14   17   38                                             
CONECT   14   13   15                                                       
CONECT   15   14   16                                                       
CONECT   16   15   17   18   36                                             
CONECT   17   16   13                                                       
CONECT   18   16   19   29                                                  
CONECT   19   18   20                                                       
CONECT   20   19   21                                                       
CONECT   21   20   22   27                                                  
CONECT   22   21   23                                                       
CONECT   23   22   24   25                                                  
CONECT   24   23                                                            
CONECT   25   23   26                                                       
CONECT   26   25   27                                                       
CONECT   27   26   21   28   29                                             
CONECT   28   27                                                            
CONECT   29   27   18   30                                                  
CONECT   30   29   31                                                       
CONECT   31   30   32   36                                                  
CONECT   32   31   33                                                       
CONECT   33   32   34   35                                                  
CONECT   34   33                                                            
CONECT   35   33                                                            
CONECT   36   31   16   37   38                                             
CONECT   37   36                                                            
CONECT   38   36   13                                                       
MASTER        0    0    0    0    0    0    0    0   38    0   84    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₃₁H₄₄O₇

Average Mass

528.6860 Da

Monoisotopic Mass

528.30870 Da

IUPAC Name

(2R)-2-[(1R,2R,10R,11S,13S,14S,16R)-13-(acetyloxy)-10,14-dimethyl-7-oxo-15,19-dioxapentacyclo[14.2.1.0^{1,14}.0^{2,11}.0^{5,10}]nonadeca-5,8-dien-16-yl]-6-methylheptan-3-yl acetate

Traditional Name

(2R)-2-[(1R,2R,10R,11S,13S,14S,16R)-13-(acetyloxy)-10,14-dimethyl-7-oxo-15,19-dioxapentacyclo[14.2.1.0^{1,14}.0^{2,11}.0^{5,10}]nonadeca-5,8-dien-16-yl]-6-methylheptan-3-yl acetate

CAS Registry Number

Not Available

SMILES

CC(C)CCC(OC(C)=O)[C@@H](C)[C@]12CC[C@@]3(O1)[C@@H]1CCC4=CC(=O)C=C[C@]4(C)[C@H]1C[C@H](OC(C)=O)[C@]3(C)O2

InChI Identifier

InChI=1S/C31H44O7/c1-18(2)8-11-26(35-20(4)32)19(3)31-15-14-30(38-31)24-10-9-22-16-23(34)12-13-28(22,6)25(24)17-27(36-21(5)33)29(30,7)37-31/h12-13,16,18-19,24-27H,8-11,14-15,17H2,1-7H3/t19-,24-,25+,26?,27+,28+,29+,30-,31+/m1/s1

InChI Key

VZAQLESCSMZQIM-PZKLDJMMSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Not Available

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as 3-oxo delta-1,4-steroids. These are 3-oxo steroids containing a double bond between positions 1 and 2, as well as positions 4 and 5.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Steroids and steroid derivatives

Sub Class

Oxosteroids

Direct Parent

3-oxo delta-1,4-steroids

Alternative Parents

Substituents

3-oxo-delta-1,4-steroid
Delta-1,4-steroid
Naphthopyran
Naphthalene
Ketal
Dicarboxylic acid or derivatives
Pyran
Oxane
Meta-dioxolane
Tetrahydrofuran
Carboxylic acid ester
Ketone
Cyclic ketone
Oxacycle
Carboxylic acid derivative
Organoheterocyclic compound
Acetal
Organic oxide
Hydrocarbon derivative
Organic oxygen compound
Carbonyl group
Organooxygen compound
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	5.29	ChemAxon
pKa (Strongest Acidic)	18.47	ChemAxon
pKa (Strongest Basic)	-4.1	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	5	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	88.13 Å²	ChemAxon
Rotatable Bond Count	9	ChemAxon
Refractivity	142.87 m³·mol⁻¹	ChemAxon
Polarizability	57.59 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

C00049730

Chemspider ID

10208266

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

21589552

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for (2r)-2-[(1r,2r,10r,11s,13s,14s,16r)-13-(acetyloxy)-10,14-dimethyl-7-oxo-15,19-dioxapentacyclo[14.2.1.0¹,¹⁴.0²,¹¹.0⁵,¹⁰]nonadeca-5,8-dien-16-yl]-6-methylheptan-3-yl acetate (NP0209698)

MOL for NP0209698 ((2r)-2-[(1r,2r,10r,11s,13s,14s,16r)-13-(acetyloxy)-10,14-dimethyl-7-oxo-15,19-dioxapentacyclo[14.2.1.0¹,¹⁴.0²,¹¹.0⁵,¹⁰]nonadeca-5,8-dien-16-yl]-6-methylheptan-3-yl acetate)

3D MOL for NP0209698 ((2r)-2-[(1r,2r,10r,11s,13s,14s,16r)-13-(acetyloxy)-10,14-dimethyl-7-oxo-15,19-dioxapentacyclo[14.2.1.0¹,¹⁴.0²,¹¹.0⁵,¹⁰]nonadeca-5,8-dien-16-yl]-6-methylheptan-3-yl acetate)

3D SDF for NP0209698 ((2r)-2-[(1r,2r,10r,11s,13s,14s,16r)-13-(acetyloxy)-10,14-dimethyl-7-oxo-15,19-dioxapentacyclo[14.2.1.0¹,¹⁴.0²,¹¹.0⁵,¹⁰]nonadeca-5,8-dien-16-yl]-6-methylheptan-3-yl acetate)

3D-SDF for NP0209698 ((2r)-2-[(1r,2r,10r,11s,13s,14s,16r)-13-(acetyloxy)-10,14-dimethyl-7-oxo-15,19-dioxapentacyclo[14.2.1.0¹,¹⁴.0²,¹¹.0⁵,¹⁰]nonadeca-5,8-dien-16-yl]-6-methylheptan-3-yl acetate)

PDB for NP0209698 ((2r)-2-[(1r,2r,10r,11s,13s,14s,16r)-13-(acetyloxy)-10,14-dimethyl-7-oxo-15,19-dioxapentacyclo[14.2.1.0¹,¹⁴.0²,¹¹.0⁵,¹⁰]nonadeca-5,8-dien-16-yl]-6-methylheptan-3-yl acetate)

3D PDB for NP0209698 ((2r)-2-[(1r,2r,10r,11s,13s,14s,16r)-13-(acetyloxy)-10,14-dimethyl-7-oxo-15,19-dioxapentacyclo[14.2.1.0¹,¹⁴.0²,¹¹.0⁵,¹⁰]nonadeca-5,8-dien-16-yl]-6-methylheptan-3-yl acetate)

SMILES for NP0209698 ((2r)-2-[(1r,2r,10r,11s,13s,14s,16r)-13-(acetyloxy)-10,14-dimethyl-7-oxo-15,19-dioxapentacyclo[14.2.1.0¹,¹⁴.0²,¹¹.0⁵,¹⁰]nonadeca-5,8-dien-16-yl]-6-methylheptan-3-yl acetate)

INCHI for NP0209698 ((2r)-2-[(1r,2r,10r,11s,13s,14s,16r)-13-(acetyloxy)-10,14-dimethyl-7-oxo-15,19-dioxapentacyclo[14.2.1.0¹,¹⁴.0²,¹¹.0⁵,¹⁰]nonadeca-5,8-dien-16-yl]-6-methylheptan-3-yl acetate)

Structure for NP0209698 ((2r)-2-[(1r,2r,10r,11s,13s,14s,16r)-13-(acetyloxy)-10,14-dimethyl-7-oxo-15,19-dioxapentacyclo[14.2.1.0¹,¹⁴.0²,¹¹.0⁵,¹⁰]nonadeca-5,8-dien-16-yl]-6-methylheptan-3-yl acetate)

3D Structure for NP0209698 ((2r)-2-[(1r,2r,10r,11s,13s,14s,16r)-13-(acetyloxy)-10,14-dimethyl-7-oxo-15,19-dioxapentacyclo[14.2.1.0¹,¹⁴.0²,¹¹.0⁵,¹⁰]nonadeca-5,8-dien-16-yl]-6-methylheptan-3-yl acetate)