NP-MRD: Showing NP-Card for 1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid (NP0209642)

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Record Information

Version

2.0

Created at

2022-09-05 07:08:01 UTC

Updated at

2022-09-05 07:08:01 UTC

NP-MRD ID

NP0209642

Secondary Accession Numbers

None

Natural Product Identification

Common Name

1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid

Description

1-(2-{5-[Carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid belongs to the class of organic compounds known as n-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. 1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid is found in Tricholoma ustale. Based on a literature review very few articles have been published on 1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309052209082D          

 32 35  0  0  0  0            999 V2000
    0.8212   -0.4741    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.1067   -0.0616    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1067    0.7634    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6078   -0.4741    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6078   -1.2991    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2752   -1.7840    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0203   -2.5687    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1953   -2.5687    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0597   -1.7840    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8443   -1.5291    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0158   -0.7221    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3514    0.0316    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8004   -0.4672    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.4679   -0.9521    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1353   -0.4672    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8804    0.3174    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0554    0.3174    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5705    0.9849    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9060    1.7386    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7500    0.8986    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4574   -2.0811    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2420   -1.8262    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8551   -2.3782    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6836   -3.1852    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8990   -3.4401    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2859   -2.8881    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3222   -0.0616    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0367   -0.4741    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7512   -0.0616    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7512    0.7634    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0367    1.1759    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3222    0.7634    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  4  2  1  4  0  0  0
  4  5  2  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  9  8  1  4  0  0  0
  5  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 11 12  2  0  0  0  0
 11 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 13 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  2  0  0  0  0
 18 20  1  0  0  0  0
 10 21  1  0  0  0  0
 21 22  2  0  0  0  0
 22 23  1  0  0  0  0
 23 24  2  0  0  0  0
 24 25  1  0  0  0  0
 25 26  2  0  0  0  0
 21 26  1  0  0  0  0
  4 27  1  0  0  0  0
 27 28  2  0  0  0  0
 28 29  1  0  0  0  0
 29 30  2  0  0  0  0
 30 31  1  0  0  0  0
 31 32  2  0  0  0  0
 27 32  1  0  0  0  0
M  END

     RDKit          3D

 53 56  0  0  0  0  0  0  0  0999 V2000
    3.3582    2.8650   -1.7353 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.2665    2.1249   -1.4364 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2988    2.3939   -2.3443 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.3961    1.3084   -0.3222 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8169    0.4838    0.4514 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6573   -0.0580    1.5654 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7102   -0.4525    2.5668 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7181   -1.0299    1.7712 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5701   -0.1534    0.6304 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5244   -0.1063   -0.0126 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6774   -0.9118    0.2556 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9324   -1.4537    1.5879 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7089   -1.6412    0.5083 N   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8860   -1.8130   -0.4124 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9150   -3.3381   -0.4177 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5972   -3.7214    1.0126 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1785   -2.4385    1.6619 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.2343   -1.7141    2.3741 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9591   -2.3095    3.2262 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4377   -0.3892    2.1174 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9337    1.0079   -0.9156 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9000    2.2710   -0.3573 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3866    3.3101   -1.1475 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8662    3.0765   -2.3986 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8742    1.7746   -2.9095 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3988    0.7204   -2.1569 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9398    1.0958   -0.0738 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4154   -0.1746   -0.2405 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7523   -0.4933   -0.0522 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.5709    0.5506    0.3145 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0789    1.8144    0.4796 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7165    2.1086    0.2809 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1026    1.8520   -3.1759 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1283   -1.1945    3.2458 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.3605    0.4682    3.1062 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7897   -1.3744    0.0011 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6716   -1.4205   -1.3969 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.8470   -3.7665   -0.7652 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0385   -3.6585   -1.0520 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6850   -4.4060    0.9849 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4169   -4.2217    1.5407 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3142   -2.6787    2.3497 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3387   -0.0329    1.8837 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5238    2.5144    0.6303 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3682    4.3108   -0.7553 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2324    3.9139   -2.9921 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2679    1.6364   -3.8936 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4178   -0.2762   -2.5941 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.7034   -0.9648   -0.5216 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.1009   -1.5142   -0.2096 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.6546    0.3402    0.4682 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6957    2.6470    0.7668 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.3099    3.1188    0.4294 H   0  0  0  0  0  0  0  0  0  0  0  0
 20 18  1  0
 18 19  2  0
 18 17  1  0
 17 16  1  0
 16 15  1  0
 15 14  1  0
 14 13  1  0
 13 11  1  0
 11 12  2  0
 11 10  1  0
 10  9  2  0
  9  8  1  0
  8  7  1  0
  7  6  1  0
  6  5  1  0
  5  4  2  0
  4  2  1  0
  2  3  1  0
  2  1  2  0
  4 27  1  0
 27 28  2  0
 28 29  1  0
 29 30  2  0
 30 31  1  0
 31 32  2  0
 10 21  1  0
 21 22  2  0
 22 23  1  0
 23 24  2  0
 24 25  1  0
 25 26  2  0
 13 17  1  0
  5  9  1  0
 32 27  1  0
 26 21  1  0
 20 43  1  0
 17 42  1  1
 16 40  1  0
 16 41  1  0
 15 38  1  0
 15 39  1  0
 14 36  1  0
 14 37  1  0
  7 34  1  0
  7 35  1  0
  3 33  1  0
 28 49  1  0
 29 50  1  0
 30 51  1  0
 31 52  1  0
 32 53  1  0
 22 44  1  0
 23 45  1  0
 24 46  1  0
 25 47  1  0
 26 48  1  0
M  END


  Mrv1652309052209082D          

 32 35  0  0  0  0            999 V2000
    0.8212   -0.4741    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.1067   -0.0616    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1067    0.7634    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6078   -0.4741    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6078   -1.2991    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2752   -1.7840    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0203   -2.5687    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1953   -2.5687    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0597   -1.7840    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8443   -1.5291    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0158   -0.7221    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3514    0.0316    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8004   -0.4672    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.4679   -0.9521    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1353   -0.4672    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8804    0.3174    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0554    0.3174    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5705    0.9849    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9060    1.7386    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7500    0.8986    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4574   -2.0811    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2420   -1.8262    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8551   -2.3782    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6836   -3.1852    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8990   -3.4401    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2859   -2.8881    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3222   -0.0616    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0367   -0.4741    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7512   -0.0616    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7512    0.7634    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0367    1.1759    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3222    0.7634    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  4  2  1  4  0  0  0
  4  5  2  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  9  8  1  4  0  0  0
  5  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 11 12  2  0  0  0  0
 11 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 13 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  2  0  0  0  0
 18 20  1  0  0  0  0
 10 21  1  0  0  0  0
 21 22  2  0  0  0  0
 22 23  1  0  0  0  0
 23 24  2  0  0  0  0
 24 25  1  0  0  0  0
 25 26  2  0  0  0  0
 21 26  1  0  0  0  0
  4 27  1  0  0  0  0
 27 28  2  0  0  0  0
 28 29  1  0  0  0  0
 29 30  2  0  0  0  0
 30 31  1  0  0  0  0
 31 32  2  0  0  0  0
 27 32  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0209642

> <DATABASE_NAME>
NP-MRD

> <SMILES>
OC(=O)C1CCCN1C(=O)C(=C1OCOC1=C(C(O)=O)C1=CC=CC=C1)C1=CC=CC=C1

> <INCHI_IDENTIFIER>
InChI=1S/C24H21NO7/c26-22(25-13-7-12-17(25)23(27)28)18(15-8-3-1-4-9-15)20-21(32-14-31-20)19(24(29)30)16-10-5-2-6-11-16/h1-6,8-11,17H,7,12-14H2,(H,27,28)(H,29,30)

> <INCHI_KEY>
KESWVSRYMSRQLW-UHFFFAOYSA-N

> <FORMULA>
C24H21NO7

> <MOLECULAR_WEIGHT>
435.432

> <EXACT_MASS>
435.13180202

> <JCHEM_ACCEPTOR_COUNT>
7

> <JCHEM_ATOM_COUNT>
53

> <JCHEM_AVERAGE_POLARIZABILITY>
42.629015509277835

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
2

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid

> <JCHEM_LOGP>
2.381160492666666

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-2

> <JCHEM_PKA>
4.384006229083443

> <JCHEM_PKA_STRONGEST_ACIDIC>
3.317578642297963

> <JCHEM_PKA_STRONGEST_BASIC>
-0.14685100191590872

> <JCHEM_POLAR_SURFACE_AREA>
113.37000000000002

> <JCHEM_REFRACTIVITY>
114.94380000000004

> <JCHEM_ROTATABLE_BOND_COUNT>
5

> <JCHEM_RULE_OF_FIVE>
1

> <JCHEM_TRADITIONAL_IUPAC>
1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 05-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   05-SEP-22         0                                  
HETATM    1  O   UNK     0       1.533  -0.885   0.000  0.00  0.00           O+0
HETATM    2  C   UNK     0       0.199  -0.115   0.000  0.00  0.00           C+0
HETATM    3  O   UNK     0       0.199   1.425   0.000  0.00  0.00           O+0
HETATM    4  C   UNK     0      -1.134  -0.885   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -1.134  -2.425   0.000  0.00  0.00           C+0
HETATM    6  O   UNK     0      -2.380  -3.330   0.000  0.00  0.00           O+0
HETATM    7  C   UNK     0      -1.904  -4.795   0.000  0.00  0.00           C+0
HETATM    8  O   UNK     0      -0.364  -4.795   0.000  0.00  0.00           O+0
HETATM    9  C   UNK     0       0.111  -3.330   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       1.576  -2.854   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       1.896  -1.348   0.000  0.00  0.00           C+0
HETATM   12  O   UNK     0       2.523   0.059   0.000  0.00  0.00           O+0
HETATM   13  N   UNK     0       3.361  -0.872   0.000  0.00  0.00           N+0
HETATM   14  C   UNK     0       4.607  -1.777   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       5.853  -0.872   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       5.377   0.593   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       3.837   0.593   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       2.932   1.838   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0       3.558   3.245   0.000  0.00  0.00           O+0
HETATM   20  O   UNK     0       1.400   1.677   0.000  0.00  0.00           O+0
HETATM   21  C   UNK     0       2.720  -3.885   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       4.185  -3.409   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       5.330  -4.439   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0       5.009  -5.946   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       3.545  -6.422   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       2.400  -5.391   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0      -2.468  -0.115   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0      -3.802  -0.885   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0      -5.136  -0.115   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0      -5.136   1.425   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0      -3.802   2.195   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0      -2.468   1.425   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3    4                                                  
CONECT    3    2                                                            
CONECT    4    2    5   27                                                  
CONECT    5    4    6    9                                                  
CONECT    6    5    7                                                       
CONECT    7    6    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8    5   10                                                  
CONECT   10    9   11   21                                                  
CONECT   11   10   12   13                                                  
CONECT   12   11                                                            
CONECT   13   11   14   17                                                  
CONECT   14   13   15                                                       
CONECT   15   14   16                                                       
CONECT   16   15   17                                                       
CONECT   17   16   13   18                                                  
CONECT   18   17   19   20                                                  
CONECT   19   18                                                            
CONECT   20   18                                                            
CONECT   21   10   22   26                                                  
CONECT   22   21   23                                                       
CONECT   23   22   24                                                       
CONECT   24   23   25                                                       
CONECT   25   24   26                                                       
CONECT   26   25   21                                                       
CONECT   27    4   28   32                                                  
CONECT   28   27   29                                                       
CONECT   29   28   30                                                       
CONECT   30   29   31                                                       
CONECT   31   30   32                                                       
CONECT   32   31   27                                                       
MASTER        0    0    0    0    0    0    0    0   32    0   70    0
END

View in JSmol

Synonyms

Value	Source
1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylate	Generator

Chemical Formula

C₂₄H₂₁NO₇

Average Mass

435.4320 Da

Monoisotopic Mass

435.13180 Da

IUPAC Name

1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid

Traditional Name

1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid

CAS Registry Number

Not Available

SMILES

OC(=O)C1CCCN1C(=O)C(=C1OCOC1=C(C(O)=O)C1=CC=CC=C1)C1=CC=CC=C1

InChI Identifier

InChI=1S/C24H21NO7/c26-22(25-13-7-12-17(25)23(27)28)18(15-8-3-1-4-9-15)20-21(32-14-31-20)19(24(29)30)16-10-5-2-6-11-16/h1-6,8-11,17H,7,12-14H2,(H,27,28)(H,29,30)

InChI Key

KESWVSRYMSRQLW-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Tricholoma ustale	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as n-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Carboxylic acids and derivatives

Sub Class

Amino acids, peptides, and analogues

Direct Parent

N-acyl-alpha amino acids

Alternative Parents

Substituents

N-acyl-alpha-amino acid
Proline or derivatives
Phenylacetamide
N-acylpyrrolidine
Pyrrolidine carboxylic acid
Pyrrolidine carboxylic acid or derivatives
Monocyclic benzene moiety
Dicarboxylic acid or derivatives
Benzenoid
Meta-dioxolane
Pyrrolidine
Tertiary carboxylic acid amide
Vinylogous ester
Carboxamide group
Acetal
Oxacycle
Carboxylic acid
Azacycle
Organoheterocyclic compound
Hydrocarbon derivative
Organooxygen compound
Organonitrogen compound
Organic oxide
Organopnictogen compound
Organic oxygen compound
Carbonyl group
Organic nitrogen compound
Aromatic heteromonocyclic compound

Molecular Framework

Aromatic heteromonocyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	2.38	ChemAxon
pKa (Strongest Acidic)	3.32	ChemAxon
pKa (Strongest Basic)	-0.15	ChemAxon
Physiological Charge	-2	ChemAxon
Hydrogen Acceptor Count	7	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	113.37 Å²	ChemAxon
Rotatable Bond Count	5	ChemAxon
Refractivity	114.94 m³·mol⁻¹	ChemAxon
Polarizability	42.63 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

163005807

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid (NP0209642)

MOL for NP0209642 (1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid)

3D MOL for NP0209642 (1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid)

3D SDF for NP0209642 (1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid)

3D-SDF for NP0209642 (1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid)

PDB for NP0209642 (1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid)

3D PDB for NP0209642 (1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid)

SMILES for NP0209642 (1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid)

INCHI for NP0209642 (1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid)

Structure for NP0209642 (1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid)

3D Structure for NP0209642 (1-(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-2-phenylacetyl)pyrrolidine-2-carboxylic acid)