NP-MRD: Showing NP-Card for ent-pimara-8(14),15-diene (NP0207383)

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Record Information

Version

2.0

Created at

2022-09-05 03:58:18 UTC

Updated at

2022-09-05 03:58:18 UTC

NP-MRD ID

NP0207383

Secondary Accession Numbers

None

Natural Product Identification

Common Name

ent-pimara-8(14),15-diene

Description

Ent-pimara-8(14),15-diene belongs to the class of organic compounds known as diterpenoids. These are terpene compounds formed by four isoprene units. Thus, ent-pimara-8(14),15-diene is considered to be an isoprenoid. ent-pimara-8(14),15-diene is found in Aldama arenaria, Sideritis discolor and Viguiera arenaria. ent-pimara-8(14),15-diene was first documented in 2009 (PMID: 19898803). Based on a literature review a significant number of articles have been published on ent-pimara-8(14),15-diene (PMID: 31690022) (PMID: 30829053) (PMID: 29665732) (PMID: 27098256) (PMID: 27093248) (PMID: 23604820).

Structure

MOL 3D MOL SDF PDB SMILES InChI

     RDKit          3D

 52 54  0  0  0  0  0  0  0  0999 V2000
    5.1879   -1.7501   -0.3167 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7211   -0.5348   -0.5398 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3768   -0.2030    0.0260 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.4553   -0.5310    1.5054 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4083   -1.1521   -0.5662 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1264   -0.8297   -0.6002 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0799   -1.6908   -1.1597 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0479   -1.7566   -0.1539 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4710   -0.4103    0.3650 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.9389   -0.2191    0.4555 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7356   -1.1881   -0.3946 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4237   -0.5156    1.8884 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4387    1.1577    0.1234 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5417    2.2696    0.4948 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0950    1.9524    0.5744 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7217    0.7382   -0.2903 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.0863    1.0301   -1.6754 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7423    0.4877   -0.0312 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.6497    1.5074   -0.6651 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0380    1.2368   -0.1310 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6511   -2.5097    0.2495 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.1677   -2.0743   -0.6976 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3135    0.1499   -1.1060 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.5013   -0.6715    1.8450 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9278   -1.4772    1.7583 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.0230    0.2883    2.1269 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.7546   -2.0906   -0.9599 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2560   -1.4134   -2.1727 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.4814   -2.7331   -1.2533 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8698   -2.3342   -0.6251 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6637   -2.4416    0.6613 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0762   -0.3751    1.4295 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4125   -1.2732   -1.4219 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7889   -2.2045    0.0456 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.8062   -0.8338   -0.4258 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5349   -0.5784    1.8107 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0811   -1.5479    2.1527 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0729    0.2536    2.5825 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7365    1.2549   -0.9627 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4190    1.3138    0.6667 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8507    2.7522    1.4675 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6600    3.1050   -0.2578 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4572    2.8115    0.3821 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8741    1.6215    1.6315 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8427    0.3851   -2.1468 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4735    2.0835   -1.8117 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1909    0.9795   -2.3311 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.8895    0.5266    1.0593 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4023    2.5467   -0.4123 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.7066    1.4356   -1.7626 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.7597    1.6696   -0.8788 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2030    1.7827    0.8235 H   0  0  0  0  0  0  0  0  0  0  0  0
 11 10  1  0
 10 12  1  0
 10 13  1  0
 13 14  1  0
 14 15  1  0
 15 16  1  0
 16 17  1  6
 16 18  1  0
 18 19  1  0
 19 20  1  0
 20  3  1  0
  3  4  1  0
  3  2  1  6
  2  1  2  3
  3  5  1  0
  5  6  2  0
  6  7  1  0
  7  8  1  0
  8  9  1  0
  9 10  1  0
  9 16  1  0
  6 18  1  0
 11 33  1  0
 11 34  1  0
 11 35  1  0
 12 36  1  0
 12 37  1  0
 12 38  1  0
 13 39  1  0
 13 40  1  0
 14 41  1  0
 14 42  1  0
 15 43  1  0
 15 44  1  0
 17 45  1  0
 17 46  1  0
 17 47  1  0
 18 48  1  1
 19 49  1  0
 19 50  1  0
 20 51  1  0
 20 52  1  0
  4 24  1  0
  4 25  1  0
  4 26  1  0
  2 23  1  0
  1 21  1  0
  1 22  1  0
  5 27  1  0
  7 28  1  0
  7 29  1  0
  8 30  1  0
  8 31  1  0
  9 32  1  1
M  END


  Mrv1652309052205582D          

 20 22  0  0  1  0            999 V2000
    1.5442    0.5178    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4009   -0.2947    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0329   -0.8250    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.4009   -1.3553    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4454   -0.1105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2704   -0.1105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6829    0.6039    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5079    0.6039    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9204   -0.1105    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.7454   -0.1105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6021    0.7019    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.5206    0.1716    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.1579   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7454   -1.5395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9204   -1.5395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5079   -0.8250    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.0954   -1.5395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6829   -0.8250    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.2704   -1.5395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4454   -1.5395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  3  2  1  6  0  0  0
  3  4  1  1  0  0  0
  3  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  9  8  1  6  0  0  0
  9 10  1  0  0  0  0
 10 11  1  0  0  0  0
 10 12  1  0  0  0  0
 10 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
  9 16  1  0  0  0  0
 16 17  1  6  0  0  0
 16 18  1  0  0  0  0
 18  6  1  6  0  0  0
 18 19  1  0  0  0  0
 19 20  1  0  0  0  0
  3 20  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0207383

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC1(C)CCC[C@@]2(C)[C@@H]3CC[C@](C)(C=C)C=C3CC[C@H]12

> <INCHI_IDENTIFIER>
InChI=1S/C20H32/c1-6-19(4)13-10-16-15(14-19)8-9-17-18(2,3)11-7-12-20(16,17)5/h6,14,16-17H,1,7-13H2,2-5H3/t16-,17-,19+,20+/m1/s1

> <INCHI_KEY>
XDSYKASBVOZOAG-JYBIWHBTSA-N

> <FORMULA>
C20H32

> <MOLECULAR_WEIGHT>
272.476

> <EXACT_MASS>
272.25040103

> <JCHEM_ACCEPTOR_COUNT>
0

> <JCHEM_ATOM_COUNT>
52

> <JCHEM_AVERAGE_POLARIZABILITY>
34.67492919568705

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(4aR,4bR,7R,10aR)-7-ethenyl-1,1,4a,7-tetramethyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydrophenanthrene

> <JCHEM_LOGP>
5.8754919800000005

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
3

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_POLAR_SURFACE_AREA>
0.0

> <JCHEM_REFRACTIVITY>
88.61759999999998

> <JCHEM_ROTATABLE_BOND_COUNT>
1

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
ent-pimara-8(14),15-diene

> <JCHEM_VEBER_RULE>
1

$$$$

HEADER    PROTEIN                                 05-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   05-SEP-22         0                                  
HETATM    1  C   UNK     0       2.882   0.966   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       2.615  -0.550   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       3.795  -1.540   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       2.615  -2.530   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       4.565  -0.206   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       6.105  -0.206   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       6.875   1.127   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       8.415   1.127   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       9.185  -0.206   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      10.725  -0.206   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0      10.457   1.310   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0      12.172   0.320   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      11.495  -1.540   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0      10.725  -2.874   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       9.185  -2.874   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       8.415  -1.540   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       7.645  -2.874   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       6.875  -1.540   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       6.105  -2.874   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       4.565  -2.874   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4    5   20                                             
CONECT    4    3                                                            
CONECT    5    3    6                                                       
CONECT    6    5    7   18                                                  
CONECT    7    6    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8   10   16                                                  
CONECT   10    9   11   12   13                                             
CONECT   11   10                                                            
CONECT   12   10                                                            
CONECT   13   10   14                                                       
CONECT   14   13   15                                                       
CONECT   15   14   16                                                       
CONECT   16   15    9   17   18                                             
CONECT   17   16                                                            
CONECT   18   16    6   19                                                  
CONECT   19   18   20                                                       
CONECT   20   19    3                                                       
MASTER        0    0    0    0    0    0    0    0   20    0   44    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₀H₃₂

Average Mass

272.4760 Da

Monoisotopic Mass

272.25040 Da

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

Not Available

SMILES

CC1(C)CCC[C@@]2(C)[C@@H]3CC[C@](C)(C=C)C=C3CC[C@H]12

InChI Identifier

InChI=1S/C20H32/c1-6-19(4)13-10-16-15(14-19)8-9-17-18(2,3)11-7-12-20(16,17)5/h6,14,16-17H,1,7-13H2,2-5H3/t16-,17-,19+,20+/m1/s1

InChI Key

XDSYKASBVOZOAG-JYBIWHBTSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Aldama arenaria	LOTUS Database	35616633
Sideritis discolor	LOTUS Database	35616633
Viguiera arenaria	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as diterpenoids. These are terpene compounds formed by four isoprene units.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Diterpenoids

Direct Parent

Diterpenoids

Alternative Parents

Substituents

Pimarane diterpenoid
Diterpenoid
Phenanthrene
Hydrophenanthrene
Polycyclic hydrocarbon
Cyclic olefin
Unsaturated aliphatic hydrocarbon
Unsaturated hydrocarbon
Olefin
Hydrocarbon
Aliphatic homopolycyclic compound

Molecular Framework

Aliphatic homopolycyclic compounds

External Descriptors

pimaradiene (CHEBI:50063 )
Pimarane diterpenoids (LMPR0104080004 )

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

C00048379

Chemspider ID

21865696

KEGG Compound ID

C18228

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

12314280

PDB ID

Not Available

ChEBI ID

50063

Good Scents ID

Not Available

References

General References

Jung HA, Lee EJ, Kim JS, Kang SS, Lee JH, Min BS, Choi JS: Cholinesterase and BACE1 inhibitory diterpenoids from Aralia cordata. Arch Pharm Res. 2009 Oct;32(10):1399-408. doi: 10.1007/s12272-009-2009-0. Epub 2009 Nov 8. [PubMed:19898803 ]
Hong R, Kim KS, Choi GM, Yeom M, Lee B, Lee S, Kang KS, Lee HS, Park HJ, Hahm DH: Continentalic Acid Rather Than Kaurenoic Acid Is Responsible for the Anti-Arthritic Activity of Manchurian Spikenard In Vitro and In Vivo. Int J Mol Sci. 2019 Nov 4;20(21). pii: ijms20215488. doi: 10.3390/ijms20215488. [PubMed:31690022 ]
Li YH, Li HR, Yang CT, Tian K, Yang C, Sun JX, Wang W, Huang XZ: Three new diterpenoids from Aralia dumetorum. J Asian Nat Prod Res. 2019 Apr;21(4):308-315. doi: 10.1080/10286020.2019.1567503. Epub 2019 Mar 4. [PubMed:30829053 ]
Zhang SN, Zeng J, Tan YN, Ma RJ, Zhang GJ, Wang HS, Tan QG: 3alpha,19-Dihydroxyl-ent-pimara-8(14),15-diene, a new diterpenoid from the rhizomes of Ricinus communis. J Asian Nat Prod Res. 2019 Jun;21(6):522-527. doi: 10.1080/10286020.2018.1461087. Epub 2018 Apr 18. [PubMed:29665732 ]
Bromann K, Toivari M, Viljanen K, Ruohonen L, Nakari-Setala T: Engineering Aspergillus nidulans for heterologous ent-kaurene and gamma-terpinene production. Appl Microbiol Biotechnol. 2016 Jul;100(14):6345-6359. doi: 10.1007/s00253-016-7517-5. Epub 2016 Apr 20. [PubMed:27098256 ]
Jiang ZY, Yang CT, Hou SQ, Tian K, Wang W, Hu QF, Huang XZ: Cytotoxic Diterpenoids from the Roots of Aralia melanocarpa. Planta Med. 2016 May;82(8):742-6. doi: 10.1055/s-0042-104349. Epub 2016 Apr 19. [PubMed:27093248 ]
Jung HA, Cho YS, Oh SH, Lee S, Min BS, Moon KH, Choi JS: Kinetics and molecular docking studies of pimarane-type diterpenes as protein tyrosine phosphatase (PTP1B) inhibitors from Aralia continentalis roots. Arch Pharm Res. 2013 Aug;36(8):957-65. doi: 10.1007/s12272-013-0131-5. Epub 2013 Apr 21. [PubMed:23604820 ]
Jung HJ, Jung HA, Kang SS, Lee JH, Cho YS, Moon KH, Choi JS: Inhibitory activity of Aralia continentalis roots on protein tyrosine phosphatase 1B and rat lens aldose reductase. Arch Pharm Res. 2012 Oct;35(10):1771-7. doi: 10.1007/s12272-012-1009-7. Epub 2012 Nov 9. [PubMed:23139128 ]
Bromann K, Toivari M, Viljanen K, Vuoristo A, Ruohonen L, Nakari-Setala T: Identification and characterization of a novel diterpene gene cluster in Aspergillus nidulans. PLoS One. 2012;7(4):e35450. doi: 10.1371/journal.pone.0035450. Epub 2012 Apr 10. [PubMed:22506079 ]
Lim H, Jung HA, Choi JS, Kim YS, Kang SS, Kim HP: Anti-inflammatory activity of the constituents of the roots of Aralia continentalis. Arch Pharm Res. 2009 Sep;32(9):1237-43. doi: 10.1007/s12272-009-1909-3. Epub 2009 Sep 26. [PubMed:19784580 ]
LOTUS database [Link]

Showing NP-Card for ent-pimara-8(14),15-diene (NP0207383)

MOL for NP0207383 (ent-pimara-8(14),15-diene)

3D MOL for NP0207383 (ent-pimara-8(14),15-diene)

3D SDF for NP0207383 (ent-pimara-8(14),15-diene)

3D-SDF for NP0207383 (ent-pimara-8(14),15-diene)

PDB for NP0207383 (ent-pimara-8(14),15-diene)

3D PDB for NP0207383 (ent-pimara-8(14),15-diene)

SMILES for NP0207383 (ent-pimara-8(14),15-diene)

INCHI for NP0207383 (ent-pimara-8(14),15-diene)

Structure for NP0207383 (ent-pimara-8(14),15-diene)

3D Structure for NP0207383 (ent-pimara-8(14),15-diene)