NP-MRD: Showing NP-Card for {[(4e,6z,8s,9s,10e,12s,13r,14s,16s,17r)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid (NP0205767)

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Record Information

Version

1.0

Created at

2022-09-05 01:45:34 UTC

Updated at

2022-09-05 01:45:34 UTC

NP-MRD ID

NP0205767

Secondary Accession Numbers

None

Natural Product Identification

Common Name

{[(4e,6z,8s,9s,10e,12s,13r,14s,16s,17r)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid

Description

Dihydro-herbimycin A belongs to the class of organic compounds known as macrolactams. These are cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. They are nitrogen analogues (the a nitrogen atom replacing the o atom of the cyclic carboxylic acid group ) of the naturally occurring macrolides. {[(4e,6z,8s,9s,10e,12s,13r,14s,16s,17r)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid is found in Streptomyces hygroscopicus. It was first documented in 2022 (PMID: 36051722). Based on a literature review a significant number of articles have been published on dihydro-herbimycin A (PMID: 36050584) (PMID: 36044365) (PMID: 36043368) (PMID: 36038174).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309052203452D          

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M  END

     RDKit          3D

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M  END


  Mrv1652309052203452D          

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    2.5032    2.3949    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3256    2.3296    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6803    1.5847    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5027    1.5194    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.7934    3.0092    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.9710    3.0745    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6163    3.8193    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4387    3.7540    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.8117    4.2903    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9065    4.4336    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7289    4.3683    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.1966    5.0479    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8420    5.7928    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0835    3.6235    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.5513    4.3031    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.3737    4.2378    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9060    3.5582    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.6838    3.8330    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2606    2.8133    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7929    2.1337    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9705    2.1990    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.1475    1.3888    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.9699    1.3236    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.4377    2.0031    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0830    2.7480    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    8.2601    1.9379    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  3  2  1  6  0  0  0
  3  4  1  0  0  0  0
  4  5  2  0  0  0  0
  5  6  1  0  0  0  0
  6  7  2  0  0  0  0
  7  8  1  0  0  0  0
  7  9  1  0  0  0  0
  9 10  1  0  0  0  0
  9 11  2  0  0  0  0
 11 12  1  4  0  0  0
 12 13  2  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 14 16  2  0  0  0  0
 16 17  1  0  0  0  0
 17 18  2  0  0  0  0
 12 18  1  0  0  0  0
 18 19  1  0  0  0  0
 17 20  1  0  0  0  0
 20 21  1  1  0  0  0
 21 22  1  0  0  0  0
 20 23  1  0  0  0  0
 23 24  1  1  0  0  0
 23 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  6  0  0  0
 27 28  1  0  0  0  0
 26 29  1  0  0  0  0
 29 30  1  1  0  0  0
 30 31  1  0  0  0  0
 29 32  1  0  0  0  0
 32 33  1  1  0  0  0
 32 34  1  0  0  0  0
 34 35  2  0  0  0  0
 35 36  1  0  0  0  0
 35 37  1  0  0  0  0
  3 37  1  0  0  0  0
 37 38  1  6  0  0  0
 38 39  1  0  0  0  0
 39 40  2  0  0  0  0
 39 41  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0205767

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CO[C@H]1C[C@H](C)[C@@H](OC)C2=C(O)C(=CC(O)=C2)N=C(O)\C(C)=C\C=C/[C@H](OC)[C@@H](OC(O)=N)\C(C)=C\[C@H](C)[C@H]1OC

> <INCHI_IDENTIFIER>
InChI=1S/C30H44N2O9/c1-16-10-9-11-23(37-5)28(41-30(31)36)18(3)12-17(2)27(40-8)24(38-6)13-19(4)26(39-7)21-14-20(33)15-22(25(21)34)32-29(16)35/h9-12,14-15,17,19,23-24,26-28,33-34H,13H2,1-8H3,(H2,31,36)(H,32,35)/b11-9-,16-10+,18-12+/t17-,19-,23-,24-,26+,27+,28-/m0/s1

> <INCHI_KEY>
QANBQEQVJJKJTJ-BVXDHVRPSA-N

> <FORMULA>
C30H44N2O9

> <MOLECULAR_WEIGHT>
576.687

> <EXACT_MASS>
576.304681005

> <JCHEM_ACCEPTOR_COUNT>
11

> <JCHEM_ATOM_COUNT>
85

> <JCHEM_AVERAGE_POLARIZABILITY>
60.271482987157334

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
5

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
{[(4E,6Z,8S,9S,10E,12S,13R,14S,16S,17R)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid

> <JCHEM_LOGP>
2.1316664389554836

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
-0.6195081500376522

> <JCHEM_PKA_STRONGEST_ACIDIC>
-2.893786968327265

> <JCHEM_PKA_STRONGEST_BASIC>
15.791561429346967

> <JCHEM_POLAR_SURFACE_AREA>
163.27999999999997

> <JCHEM_REFRACTIVITY>
170.33160000000004

> <JCHEM_ROTATABLE_BOND_COUNT>
6

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
{[(4E,6Z,8S,9S,10E,12S,13R,14S,16S,17R)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 05-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   05-SEP-22         0                                  
HETATM    1  C   UNK     0      12.799  -0.188   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0      12.137   1.202   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0      10.602   1.324   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      11.264  -0.066   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      10.391  -1.335   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       8.707  -1.275   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       7.485  -2.211   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       7.524  -3.751   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       6.216  -1.338   0.000  0.00  0.00           C+0
HETATM   10  O   UNK     0       4.764  -1.851   0.000  0.00  0.00           O+0
HETATM   11  N   UNK     0       6.654   0.138   0.000  0.00  0.00           N+0
HETATM   12  C   UNK     0       5.997   1.690   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       4.462   1.811   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       3.800   3.202   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0       2.264   3.324   0.000  0.00  0.00           O+0
HETATM   16  C   UNK     0       4.673   4.470   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       6.208   4.349   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       6.870   2.958   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0       8.405   2.836   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0       7.081   5.617   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0       5.546   5.739   0.000  0.00  0.00           O+0
HETATM   22  C   UNK     0       4.884   7.129   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       6.419   7.008   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0       5.249   8.008   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       7.292   8.276   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       8.827   8.154   0.000  0.00  0.00           C+0
HETATM   27  O   UNK     0       9.700   9.423   0.000  0.00  0.00           O+0
HETATM   28  C   UNK     0       9.038  10.813   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       9.489   6.764   0.000  0.00  0.00           C+0
HETATM   30  O   UNK     0      10.362   8.032   0.000  0.00  0.00           O+0
HETATM   31  C   UNK     0      11.898   7.910   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0      11.024   6.642   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0      12.476   7.155   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0      11.686   5.252   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0      10.813   3.983   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0       9.278   4.105   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0      11.475   2.593   0.000  0.00  0.00           C+0
HETATM   38  O   UNK     0      13.011   2.471   0.000  0.00  0.00           O+0
HETATM   39  C   UNK     0      13.884   3.739   0.000  0.00  0.00           C+0
HETATM   40  N   UNK     0      13.222   5.130   0.000  0.00  0.00           N+0
HETATM   41  O   UNK     0      15.419   3.617   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4   37                                                  
CONECT    4    3    5                                                       
CONECT    5    4    6                                                       
CONECT    6    5    7                                                       
CONECT    7    6    8    9                                                  
CONECT    8    7                                                            
CONECT    9    7   10   11                                                  
CONECT   10    9                                                            
CONECT   11    9   12                                                       
CONECT   12   11   13   18                                                  
CONECT   13   12   14                                                       
CONECT   14   13   15   16                                                  
CONECT   15   14                                                            
CONECT   16   14   17                                                       
CONECT   17   16   18   20                                                  
CONECT   18   17   12   19                                                  
CONECT   19   18                                                            
CONECT   20   17   21   23                                                  
CONECT   21   20   22                                                       
CONECT   22   21                                                            
CONECT   23   20   24   25                                                  
CONECT   24   23                                                            
CONECT   25   23   26                                                       
CONECT   26   25   27   29                                                  
CONECT   27   26   28                                                       
CONECT   28   27                                                            
CONECT   29   26   30   32                                                  
CONECT   30   29   31                                                       
CONECT   31   30                                                            
CONECT   32   29   33   34                                                  
CONECT   33   32                                                            
CONECT   34   32   35                                                       
CONECT   35   34   36   37                                                  
CONECT   36   35                                                            
CONECT   37   35    3   38                                                  
CONECT   38   37   39                                                       
CONECT   39   38   40   41                                                  
CONECT   40   39                                                            
CONECT   41   39                                                            
MASTER        0    0    0    0    0    0    0    0   41    0   84    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₃₀H₄₄N₂O₉

Average Mass

576.6870 Da

Monoisotopic Mass

576.30468 Da

IUPAC Name

{[(4E,6Z,8S,9S,10E,12S,13R,14S,16S,17R)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid

Traditional Name

{[(4E,6Z,8S,9S,10E,12S,13R,14S,16S,17R)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid

CAS Registry Number

Not Available

SMILES

CO[C@H]1C[C@H](C)[C@@H](OC)C2=C(O)C(=CC(O)=C2)N=C(O)\C(C)=C\C=C/[C@H](OC)[C@@H](OC(O)=N)\C(C)=C\[C@H](C)[C@H]1OC

InChI Identifier

InChI=1S/C30H44N2O9/c1-16-10-9-11-23(37-5)28(41-30(31)36)18(3)12-17(2)27(40-8)24(38-6)13-19(4)26(39-7)21-14-20(33)15-22(25(21)34)32-29(16)35/h9-12,14-15,17,19,23-24,26-28,33-34H,13H2,1-8H3,(H2,31,36)(H,32,35)/b11-9-,16-10+,18-12+/t17-,19-,23-,24-,26+,27+,28-/m0/s1

InChI Key

QANBQEQVJJKJTJ-BVXDHVRPSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Streptomyces hygroscopicus	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as macrolactams. These are cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. They are nitrogen analogues (the a nitrogen atom replacing the o atom of the cyclic carboxylic acid group ) of the naturally occurring macrolides.

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Macrolactams

Sub Class

Not Available

Direct Parent

Macrolactams

Alternative Parents

Substituents

Macrolactam
1-hydroxy-2-unsubstituted benzenoid
Phenol
Benzenoid
Carbamic acid ester
Carboxamide group
Lactam
Secondary carboxylic acid amide
Carboxylic acid derivative
Dialkyl ether
Ether
Azacycle
Organoheterocyclic compound
Organic oxide
Organic oxygen compound
Organic nitrogen compound
Organonitrogen compound
Organooxygen compound
Hydrocarbon derivative
Carbonyl group
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	2.13	ChemAxon
pKa (Strongest Acidic)	-2.9	ChemAxon
pKa (Strongest Basic)	15.79	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	11	ChemAxon
Hydrogen Donor Count	5	ChemAxon
Polar Surface Area	163.28 Å²	ChemAxon
Rotatable Bond Count	6	ChemAxon
Refractivity	170.33 m³·mol⁻¹	ChemAxon
Polarizability	60.27 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

23327406

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

13491580

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Wako M, Kono H, Koyama K, Fujimaki T, Furuya N, Haro H: The Anatomical Position of Graf's Standard Plane and Its Relationship With Pelvic Morphology: A Computed Tomography-Based Study. Cureus. 2022 Jul 28;14(7):e27424. doi: 10.7759/cureus.27424. eCollection 2022 Jul. [PubMed:36051722 ]
Jayroe M, Aguilar DR, Porter A, Cima M, Chai S, Hayman K: Transmission Analysis of COVID-19 Outbreaks Associated with Places of Worship, Arkansas, May 2020-December 2020. J Relig Health. 2022 Sep 1. pii: 10.1007/s10943-022-01653-y. doi: 10.1007/s10943-022-01653-y. [PubMed:36050584 ]
Belik AA, Khalyavin DD, Matsushita Y, Yamaura K: Triple A-Site Cation Ordering in the Ferrimagnetic Y2CuGaMn4O12 Perovskite. Inorg Chem. 2022 Sep 12;61(36):14428-14435. doi: 10.1021/acs.inorgchem.2c02343. Epub 2022 Aug 31. [PubMed:36044365 ]
Siwach P, Sikarwar P, Rajput SA, Antharjanam S, Chandiran AK: The effect of halogenated spacer cations on structural symmetry-breaking in 2D halide double perovskites. Chem Commun (Camb). 2022 Aug 31. doi: 10.1039/d2cc02747j. [PubMed:36043368 ]
Abukhadijah HJ, Turk-Adawi KI, Dewart N, Grace SL: Qualitative study measuring the usability of the International Cardiac Rehabilitation Registry. BMJ Open. 2022 Aug 29;12(8):e064255. doi: 10.1136/bmjopen-2022-064255. [PubMed:36038174 ]
LOTUS database [Link]

Showing NP-Card for {[(4e,6z,8s,9s,10e,12s,13r,14s,16s,17r)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid (NP0205767)

MOL for NP0205767 ({[(4e,6z,8s,9s,10e,12s,13r,14s,16s,17r)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid)

3D MOL for NP0205767 ({[(4e,6z,8s,9s,10e,12s,13r,14s,16s,17r)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid)

3D SDF for NP0205767 ({[(4e,6z,8s,9s,10e,12s,13r,14s,16s,17r)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid)

3D-SDF for NP0205767 ({[(4e,6z,8s,9s,10e,12s,13r,14s,16s,17r)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid)

PDB for NP0205767 ({[(4e,6z,8s,9s,10e,12s,13r,14s,16s,17r)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid)

3D PDB for NP0205767 ({[(4e,6z,8s,9s,10e,12s,13r,14s,16s,17r)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid)

SMILES for NP0205767 ({[(4e,6z,8s,9s,10e,12s,13r,14s,16s,17r)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid)

INCHI for NP0205767 ({[(4e,6z,8s,9s,10e,12s,13r,14s,16s,17r)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid)

Structure for NP0205767 ({[(4e,6z,8s,9s,10e,12s,13r,14s,16s,17r)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid)

3D Structure for NP0205767 ({[(4e,6z,8s,9s,10e,12s,13r,14s,16s,17r)-3,20,22-trihydroxy-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18(22),19-heptaen-9-yl]oxy}methanimidic acid)