NP-MRD: Showing NP-Card for (2s,6s)-6-hydroxy-2-methyl-4-oxo-6-[(1s,3s,5r,7r,8r,10s,14r,17r,18s)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadeca-11,15-dien-15-yl]heptanoic acid (NP0205018)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-05 00:49:55 UTC

Updated at

2022-09-05 00:49:55 UTC

NP-MRD ID

NP0205018

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(2s,6s)-6-hydroxy-2-methyl-4-oxo-6-[(1s,3s,5r,7r,8r,10s,14r,17r,18s)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadeca-11,15-dien-15-yl]heptanoic acid

Description

(2S,6S)-6-hydroxy-2-methyl-4-oxo-6-[(1S,3S,5R,7R,8R,10S,14R,17R,18S)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]Octadeca-11,15-dien-15-yl]heptanoic acid belongs to the class of organic compounds known as bile acids, alcohols and derivatives. These are organic compounds containing an alcohol or acid derivative of cholic acid. (2s,6s)-6-hydroxy-2-methyl-4-oxo-6-[(1s,3s,5r,7r,8r,10s,14r,17r,18s)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadeca-11,15-dien-15-yl]heptanoic acid is found in Ganoderma applanatum. Based on a literature review very few articles have been published on (2S,6S)-6-hydroxy-2-methyl-4-oxo-6-[(1S,3S,5R,7R,8R,10S,14R,17R,18S)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]Octadeca-11,15-dien-15-yl]heptanoic acid.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309052202492D          

 39 43  0  0  1  0            999 V2000
    0.2771   -6.0847    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5402   -5.9718    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.8511   -5.2077    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3447   -4.5563    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4725   -4.6692    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6556   -3.7922    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1493   -3.1408    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.8006   -2.6345    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5021   -3.6472    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3571   -2.4895    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1278   -1.6970    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8106   -1.2340    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.8374   -0.4095    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4620   -1.7404    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.4024   -0.9175    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2741   -1.5952    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.7423   -0.9645    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.5544   -0.8192    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.3665   -0.6740    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8983   -1.3047    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.7104   -1.1595    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4264   -0.3850    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4239   -0.7453    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2423   -1.7902    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.0544   -1.6450    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.9620   -2.5662    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.4938   -3.1969    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.1498   -2.7114    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6180   -2.0807    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.3377   -2.8566    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8059   -2.2259    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5256   -3.0018    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7135   -3.1470    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4332   -3.9229    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.1817   -2.5163    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.8218   -3.2587    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0465   -6.6232    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7356   -7.3874    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8638   -6.5103    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  2  1  1  6  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  2  0  0  0  0
  4  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  6  0  0  0
  7  9  1  6  0  0  0
  7 10  1  0  0  0  0
 10 11  2  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  1  0  0  0
 12 14  1  0  0  0  0
 14 15  1  6  0  0  0
 14 16  1  0  0  0  0
 16 17  1  1  0  0  0
 18 17  1  1  0  0  0
 16 18  1  0  0  0  0
 18 19  1  0  0  0  0
 20 19  1  1  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 21 23  1  0  0  0  0
 21 24  1  0  0  0  0
 24 25  1  1  0  0  0
 24 26  1  0  0  0  0
 26 27  1  6  0  0  0
 26 28  1  0  0  0  0
 28 29  1  0  0  0  0
 20 29  1  0  0  0  0
 29 30  1  1  0  0  0
 29 31  1  0  0  0  0
 16 31  1  0  0  0  0
 31 32  2  0  0  0  0
 32 33  1  0  0  0  0
 33 34  2  0  0  0  0
 33 35  1  0  0  0  0
 10 35  1  0  0  0  0
 14 35  1  0  0  0  0
 35 36  1  1  0  0  0
  2 37  1  0  0  0  0
 37 38  2  0  0  0  0
 37 39  1  0  0  0  0
M  END

     RDKit          3D

 81 85  0  0  0  0  0  0  0  0999 V2000
    8.2019   -2.3491   -0.8166 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.9454   -1.5771   -1.1390 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.1227   -1.4092    0.1364 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8940   -0.6380   -0.2460 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2035   -1.1083   -1.1195 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.6587    0.6179    0.4870 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3512    1.3068    0.0978 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.4649    1.5537   -1.3799 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4422    2.5761    0.7438 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1714    0.5770    0.5665 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3092   -0.6235    1.1983 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9755   -1.1631    1.5753 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.6230   -0.8402    2.8664 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.1173   -0.4993    0.5437 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.3043   -1.1465   -0.8000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3128   -0.3878    0.8818 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.7099   -0.7208    2.1657 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0933   -1.5594    1.0880 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.5363   -1.5844    0.7185 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9454   -0.4574   -0.1651 C   0  0  1  0  0  0  0  0  0  0  0  0
   -5.3870   -0.4752   -0.4852 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6327   -1.7238   -1.3571 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.2735   -0.7292    0.7407 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8728    0.6904   -1.2845 C   0  0  1  0  0  0  0  0  0  0  0  0
   -6.8858    1.4061   -0.6591 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7514    1.6755   -1.5566 C   0  0  2  0  0  0  0  0  0  0  0  0
   -3.8429    1.2415   -2.4865 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1160    2.0221   -0.2053 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4413    0.8535    0.4018 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.6483    0.9690    1.9048 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9530    0.7770    0.2147 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3221    1.6877   -0.4772 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1561    1.5519   -0.6072 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6442    2.0084   -1.6420 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7693    0.8924    0.5328 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.4272    1.6051    1.8442 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.2557   -0.2302   -1.6787 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.9146    0.1200   -2.8230 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.9548    0.6513   -0.8542 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.0425   -1.8474   -1.3580 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.0972   -3.3806   -1.1742 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.3863   -2.3732    0.2852 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.3495   -2.1421   -1.8578 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.7761   -2.4299    0.4716 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.7144   -0.9236    0.9164 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.6653    0.3724    1.5666 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.4688    1.3432    0.2852 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9653    0.7936   -1.9976 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.5706    1.5055   -1.6990 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2147    2.6097   -1.6419 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.7300    3.2739    0.1228 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2157   -1.1615    1.4319 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.9644   -2.2546    1.3760 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.3258   -1.6607    3.3368 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.3287   -1.6170   -0.8741 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4054   -2.0246   -0.8312 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.0549   -0.5114   -1.6508 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5480   -2.5516    1.1039 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6811   -2.5204    0.0950 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2140   -1.7675    1.5867 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3701   -0.5981   -1.1298 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.6521   -1.6347   -1.7835 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6304   -2.6335   -0.7117 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.8508   -1.8350   -2.1218 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.3229   -0.6121    0.3982 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1649   -1.7986    1.0151 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1056   -0.0277    1.5479 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.2772    0.4006   -2.2807 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.8546    1.4098    0.3079 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2416    2.6072   -1.9171 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2068    1.3831   -3.3832 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5650    2.9578   -0.2918 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.0362    2.3304    0.4057 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5174    1.6587    2.1218 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7832    1.5054    2.3667 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8761    0.0440    2.4149 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8190    2.5240   -0.9664 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2192    2.6808    1.6751 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2952    1.5793    2.5306 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4249    1.1867    2.3667 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.9803    0.5789    0.1558 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  4  5  2  0
  4  6  1  0
  6  7  1  0
  7  8  1  0
  7  9  1  1
  7 10  1  0
 10 11  2  0
 11 12  1  0
 12 13  1  0
 12 14  1  0
 14 15  1  6
 14 16  1  0
 16 17  1  1
 17 18  1  0
 18 19  1  0
 19 20  1  0
 20 21  1  0
 21 22  1  0
 21 23  1  0
 21 24  1  0
 24 25  1  0
 24 26  1  0
 26 27  1  0
 26 28  1  0
 28 29  1  0
 29 30  1  1
 29 31  1  0
 31 32  2  0
 32 33  1  0
 33 34  2  0
 33 35  1  0
 35 36  1  1
  2 37  1  0
 37 39  1  0
 37 38  2  0
 35 10  1  0
 35 14  1  0
 18 16  1  0
 29 20  1  0
 31 16  1  0
  1 40  1  0
  1 41  1  0
  1 42  1  0
  2 43  1  6
  3 44  1  0
  3 45  1  0
  6 46  1  0
  6 47  1  0
  8 48  1  0
  8 49  1  0
  8 50  1  0
  9 51  1  0
 11 52  1  0
 12 53  1  1
 13 54  1  0
 15 55  1  0
 15 56  1  0
 15 57  1  0
 18 58  1  1
 19 59  1  0
 19 60  1  0
 20 61  1  6
 22 62  1  0
 22 63  1  0
 22 64  1  0
 23 65  1  0
 23 66  1  0
 23 67  1  0
 24 68  1  6
 25 69  1  0
 26 70  1  6
 27 71  1  0
 28 72  1  0
 28 73  1  0
 30 74  1  0
 30 75  1  0
 30 76  1  0
 32 77  1  0
 36 78  1  0
 36 79  1  0
 36 80  1  0
 39 81  1  0
M  END


  Mrv1652309052202492D          

 39 43  0  0  1  0            999 V2000
    0.2771   -6.0847    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5402   -5.9718    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.8511   -5.2077    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3447   -4.5563    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4725   -4.6692    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6556   -3.7922    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1493   -3.1408    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.8006   -2.6345    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5021   -3.6472    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3571   -2.4895    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1278   -1.6970    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8106   -1.2340    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.8374   -0.4095    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4620   -1.7404    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.4024   -0.9175    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2741   -1.5952    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.7423   -0.9645    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.5544   -0.8192    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.3665   -0.6740    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8983   -1.3047    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.7104   -1.1595    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4264   -0.3850    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4239   -0.7453    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2423   -1.7902    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.0544   -1.6450    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.9620   -2.5662    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.4938   -3.1969    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.1498   -2.7114    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6180   -2.0807    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.3377   -2.8566    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8059   -2.2259    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5256   -3.0018    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7135   -3.1470    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4332   -3.9229    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.1817   -2.5163    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.8218   -3.2587    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0465   -6.6232    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7356   -7.3874    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8638   -6.5103    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  2  1  1  6  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  2  0  0  0  0
  4  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  6  0  0  0
  7  9  1  6  0  0  0
  7 10  1  0  0  0  0
 10 11  2  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  1  0  0  0
 12 14  1  0  0  0  0
 14 15  1  6  0  0  0
 14 16  1  0  0  0  0
 16 17  1  1  0  0  0
 18 17  1  1  0  0  0
 16 18  1  0  0  0  0
 18 19  1  0  0  0  0
 20 19  1  1  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 21 23  1  0  0  0  0
 21 24  1  0  0  0  0
 24 25  1  1  0  0  0
 24 26  1  0  0  0  0
 26 27  1  6  0  0  0
 26 28  1  0  0  0  0
 28 29  1  0  0  0  0
 20 29  1  0  0  0  0
 29 30  1  1  0  0  0
 29 31  1  0  0  0  0
 16 31  1  0  0  0  0
 31 32  2  0  0  0  0
 32 33  1  0  0  0  0
 33 34  2  0  0  0  0
 33 35  1  0  0  0  0
 10 35  1  0  0  0  0
 14 35  1  0  0  0  0
 35 36  1  1  0  0  0
  2 37  1  0  0  0  0
 37 38  2  0  0  0  0
 37 39  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0205018

> <DATABASE_NAME>
NP-MRD

> <SMILES>
C[C@@H](CC(=O)C[C@](C)(O)C1=C[C@@H](O)[C@@]2(C)[C@]34O[C@H]3C[C@H]3C(C)(C)[C@@H](O)[C@H](O)C[C@]3(C)C4=CC(=O)[C@]12C)C(O)=O

> <INCHI_IDENTIFIER>
InChI=1S/C30H42O9/c1-14(24(36)37)8-15(31)12-27(5,38)19-10-21(34)29(7)28(19,6)20(33)9-18-26(4)13-16(32)23(35)25(2,3)17(26)11-22-30(18,29)39-22/h9-10,14,16-17,21-23,32,34-35,38H,8,11-13H2,1-7H3,(H,36,37)/t14-,16+,17-,21+,22-,23-,26-,27-,28-,29+,30+/m0/s1

> <INCHI_KEY>
DRCONWGQHWLZJX-VFCZRXNFSA-N

> <FORMULA>
C30H42O9

> <MOLECULAR_WEIGHT>
546.657

> <EXACT_MASS>
546.282882932

> <JCHEM_ACCEPTOR_COUNT>
9

> <JCHEM_ATOM_COUNT>
81

> <JCHEM_AVERAGE_POLARIZABILITY>
58.10068523265816

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
5

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2S,6S)-6-hydroxy-2-methyl-4-oxo-6-[(1S,3S,5R,7R,8R,10S,14R,17R,18S)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0^{1,3}.0^{5,10}.0^{14,18}]octadeca-11,15-dien-15-yl]heptanoic acid

> <JCHEM_LOGP>
1.0515542336666654

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA>
13.43509401028276

> <JCHEM_PKA_STRONGEST_ACIDIC>
4.0071433002510926

> <JCHEM_PKA_STRONGEST_BASIC>
-3.1390339498292406

> <JCHEM_POLAR_SURFACE_AREA>
164.89

> <JCHEM_REFRACTIVITY>
141.2135

> <JCHEM_ROTATABLE_BOND_COUNT>
6

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
(2S,6S)-6-hydroxy-2-methyl-4-oxo-6-[(1S,3S,5R,7R,8R,10S,14R,17R,18S)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0^{1,3}.0^{5,10}.0^{14,18}]octadeca-11,15-dien-15-yl]heptanoic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 05-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   05-SEP-22         0                                  
HETATM    1  C   UNK     0       0.517 -11.358   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -1.008 -11.147   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -1.589  -9.721   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -0.643  -8.505   0.000  0.00  0.00           C+0
HETATM    5  O   UNK     0       0.882  -8.716   0.000  0.00  0.00           O+0
HETATM    6  C   UNK     0      -1.224  -7.079   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      -0.279  -5.863   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      -1.494  -4.918   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0       0.937  -6.808   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0       0.667  -4.647   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       0.239  -3.168   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       1.513  -2.304   0.000  0.00  0.00           C+0
HETATM   13  O   UNK     0       1.563  -0.764   0.000  0.00  0.00           O+0
HETATM   14  C   UNK     0       2.729  -3.249   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       2.618  -1.713   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       4.245  -2.978   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0       3.252  -1.800   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0       4.768  -1.529   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       6.284  -1.258   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       7.277  -2.436   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       8.793  -2.164   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       8.263  -0.719   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      10.125  -1.391   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0       9.786  -3.342   0.000  0.00  0.00           C+0
HETATM   25  O   UNK     0      11.302  -3.071   0.000  0.00  0.00           O+0
HETATM   26  C   UNK     0       9.262  -4.790   0.000  0.00  0.00           C+0
HETATM   27  O   UNK     0      10.255  -5.967   0.000  0.00  0.00           O+0
HETATM   28  C   UNK     0       7.746  -5.061   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       6.754  -3.884   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       6.230  -5.332   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       5.238  -4.155   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       4.714  -5.603   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0       3.198  -5.874   0.000  0.00  0.00           C+0
HETATM   34  O   UNK     0       2.675  -7.323   0.000  0.00  0.00           O+0
HETATM   35  C   UNK     0       2.206  -4.697   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0       1.534  -6.083   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0      -1.954 -12.363   0.000  0.00  0.00           C+0
HETATM   38  O   UNK     0      -1.373 -13.790   0.000  0.00  0.00           O+0
HETATM   39  O   UNK     0      -3.479 -12.153   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3   37                                                  
CONECT    3    2    4                                                       
CONECT    4    3    5    6                                                  
CONECT    5    4                                                            
CONECT    6    4    7                                                       
CONECT    7    6    8    9   10                                             
CONECT    8    7                                                            
CONECT    9    7                                                            
CONECT   10    7   11   35                                                  
CONECT   11   10   12                                                       
CONECT   12   11   13   14                                                  
CONECT   13   12                                                            
CONECT   14   12   15   16   35                                             
CONECT   15   14                                                            
CONECT   16   14   17   18   31                                             
CONECT   17   16   18                                                       
CONECT   18   17   16   19                                                  
CONECT   19   18   20                                                       
CONECT   20   19   21   29                                                  
CONECT   21   20   22   23   24                                             
CONECT   22   21                                                            
CONECT   23   21                                                            
CONECT   24   21   25   26                                                  
CONECT   25   24                                                            
CONECT   26   24   27   28                                                  
CONECT   27   26                                                            
CONECT   28   26   29                                                       
CONECT   29   28   20   30   31                                             
CONECT   30   29                                                            
CONECT   31   29   16   32                                                  
CONECT   32   31   33                                                       
CONECT   33   32   34   35                                                  
CONECT   34   33                                                            
CONECT   35   33   10   14   36                                             
CONECT   36   35                                                            
CONECT   37    2   38   39                                                  
CONECT   38   37                                                            
CONECT   39   37                                                            
MASTER        0    0    0    0    0    0    0    0   39    0   86    0
END

View in JSmol

Synonyms

Value	Source
(2S,6S)-6-Hydroxy-2-methyl-4-oxo-6-[(1S,3S,5R,7R,8R,10S,14R,17R,18S)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0,.0,.0,]octadeca-11,15-dien-15-yl]heptanoate	Generator

Chemical Formula

C₃₀H₄₂O₉

Average Mass

546.6570 Da

Monoisotopic Mass

546.28288 Da

IUPAC Name

(2S,6S)-6-hydroxy-2-methyl-4-oxo-6-[(1S,3S,5R,7R,8R,10S,14R,17R,18S)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0^{1,3}.0^{5,10}.0^{14,18}]octadeca-11,15-dien-15-yl]heptanoic acid

Traditional Name

CAS Registry Number

Not Available

SMILES

C[C@@H](CC(=O)C[C@](C)(O)C1=C[C@@H](O)[C@@]2(C)[C@]34O[C@H]3C[C@H]3C(C)(C)[C@@H](O)[C@H](O)C[C@]3(C)C4=CC(=O)[C@]12C)C(O)=O

InChI Identifier

InChI=1S/C30H42O9/c1-14(24(36)37)8-15(31)12-27(5,38)19-10-21(34)29(7)28(19,6)20(33)9-18-26(4)13-16(32)23(35)25(2,3)17(26)11-22-30(18,29)39-22/h9-10,14,16-17,21-23,32,34-35,38H,8,11-13H2,1-7H3,(H,36,37)/t14-,16+,17-,21+,22-,23-,26-,27-,28-,29+,30+/m0/s1

InChI Key

DRCONWGQHWLZJX-VFCZRXNFSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Ganoderma applanatum	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as bile acids, alcohols and derivatives. These are organic compounds containing an alcohol or acid derivative of cholic acid.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Steroids and steroid derivatives

Sub Class

Bile acids, alcohols and derivatives

Direct Parent

Bile acids, alcohols and derivatives

Alternative Parents

Substituents

Bile acid, alcohol, or derivatives
Medium-chain keto acid
Gamma-keto acid
Cyclohexenone
Oxepane
Beta-hydroxy ketone
Keto acid
Cyclic alcohol
Tertiary alcohol
Ketone
Secondary alcohol
Monocarboxylic acid or derivatives
Organoheterocyclic compound
Oxacycle
Ether
Oxirane
Dialkyl ether
Carboxylic acid
Carboxylic acid derivative
Polyol
Alcohol
Hydrocarbon derivative
Carbonyl group
Organic oxide
Organic oxygen compound
Organooxygen compound
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	1.05	ChemAxon
pKa (Strongest Acidic)	4.01	ChemAxon
pKa (Strongest Basic)	-3.1	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	9	ChemAxon
Hydrogen Donor Count	5	ChemAxon
Polar Surface Area	164.89 Å²	ChemAxon
Rotatable Bond Count	6	ChemAxon
Refractivity	141.21 m³·mol⁻¹	ChemAxon
Polarizability	58.1 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

162969449

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for (2s,6s)-6-hydroxy-2-methyl-4-oxo-6-[(1s,3s,5r,7r,8r,10s,14r,17r,18s)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadeca-11,15-dien-15-yl]heptanoic acid (NP0205018)

MOL for NP0205018 ((2s,6s)-6-hydroxy-2-methyl-4-oxo-6-[(1s,3s,5r,7r,8r,10s,14r,17r,18s)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadeca-11,15-dien-15-yl]heptanoic acid)

3D MOL for NP0205018 ((2s,6s)-6-hydroxy-2-methyl-4-oxo-6-[(1s,3s,5r,7r,8r,10s,14r,17r,18s)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadeca-11,15-dien-15-yl]heptanoic acid)

3D SDF for NP0205018 ((2s,6s)-6-hydroxy-2-methyl-4-oxo-6-[(1s,3s,5r,7r,8r,10s,14r,17r,18s)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadeca-11,15-dien-15-yl]heptanoic acid)

3D-SDF for NP0205018 ((2s,6s)-6-hydroxy-2-methyl-4-oxo-6-[(1s,3s,5r,7r,8r,10s,14r,17r,18s)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadeca-11,15-dien-15-yl]heptanoic acid)

PDB for NP0205018 ((2s,6s)-6-hydroxy-2-methyl-4-oxo-6-[(1s,3s,5r,7r,8r,10s,14r,17r,18s)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadeca-11,15-dien-15-yl]heptanoic acid)

3D PDB for NP0205018 ((2s,6s)-6-hydroxy-2-methyl-4-oxo-6-[(1s,3s,5r,7r,8r,10s,14r,17r,18s)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadeca-11,15-dien-15-yl]heptanoic acid)

SMILES for NP0205018 ((2s,6s)-6-hydroxy-2-methyl-4-oxo-6-[(1s,3s,5r,7r,8r,10s,14r,17r,18s)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadeca-11,15-dien-15-yl]heptanoic acid)

INCHI for NP0205018 ((2s,6s)-6-hydroxy-2-methyl-4-oxo-6-[(1s,3s,5r,7r,8r,10s,14r,17r,18s)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadeca-11,15-dien-15-yl]heptanoic acid)

Structure for NP0205018 ((2s,6s)-6-hydroxy-2-methyl-4-oxo-6-[(1s,3s,5r,7r,8r,10s,14r,17r,18s)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadeca-11,15-dien-15-yl]heptanoic acid)

3D Structure for NP0205018 ((2s,6s)-6-hydroxy-2-methyl-4-oxo-6-[(1s,3s,5r,7r,8r,10s,14r,17r,18s)-7,8,17-trihydroxy-6,6,10,14,18-pentamethyl-13-oxo-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadeca-11,15-dien-15-yl]heptanoic acid)