NP-MRD: Showing NP-Card for (1r,2r,4s,5s,9r,10s,12s,13r,14r,16r)-2,12,16-trihydroxy-5,9,14-trimethyl-5-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)tetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecan-15-one (NP0200267)

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Record Information

Version

2.0

Created at

2022-09-04 19:04:07 UTC

Updated at

2022-09-04 19:04:07 UTC

NP-MRD ID

NP0200267

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(1r,2r,4s,5s,9r,10s,12s,13r,14r,16r)-2,12,16-trihydroxy-5,9,14-trimethyl-5-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)tetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecan-15-one

Description

ALBOPILOSIN J belongs to the class of organic compounds known as diterpene glycosides. These are diterpenoids in which an isoprene unit is glycosylated. (1r,2r,4s,5s,9r,10s,12s,13r,14r,16r)-2,12,16-trihydroxy-5,9,14-trimethyl-5-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)tetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecan-15-one is found in Isodon albopilosus. Based on a literature review very few articles have been published on ALBOPILOSIN J.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309042221042D          

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M  END

     RDKit          3D

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M  END


  Mrv1652309042221042D          

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    3.8103    2.8814    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.6283    2.7748    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.9551    0.4164    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.4015    1.0407    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5925    0.8721    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.0585    1.5009    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  2  1  1  1  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  5  3  1  1  0  0  0
  5  6  1  0  0  0  0
  6  7  1  6  0  0  0
  7  8  1  0  0  0  0
  8  9  1  6  0  0  0
  8 10  1  0  0  0  0
 10  2  1  1  0  0  0
 10 11  1  0  0  0  0
  5 11  1  0  0  0  0
 11 12  1  6  0  0  0
  6 13  1  0  0  0  0
 13 14  1  6  0  0  0
 13 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  6  0  0  0
 18 20  1  1  0  0  0
 20 21  1  0  0  0  0
 22 21  1  6  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  1  6  0  0  0
 25 26  1  0  0  0  0
 24 27  1  0  0  0  0
 27 28  1  1  0  0  0
 27 29  1  0  0  0  0
 29 30  1  6  0  0  0
 29 31  1  0  0  0  0
 22 31  1  0  0  0  0
 31 32  1  1  0  0  0
 18 33  1  0  0  0  0
 13 33  1  0  0  0  0
 33 34  1  6  0  0  0
 34 35  1  0  0  0  0
  5 35  1  0  0  0  0
 35 36  1  6  0  0  0
M  END
> <DATABASE_ID>
NP0200267

> <DATABASE_NAME>
NP-MRD

> <SMILES>
C[C@@H]1[C@H]2[C@@H](O)[C@@]3([C@H](O)C[C@@H]4[C@@](C)(CO[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)CCC[C@@]4(C)[C@@H]3C[C@@H]2O)C1=O

> <INCHI_IDENTIFIER>
InChI=1S/C26H42O10/c1-11-17-12(28)7-15-25(3)6-4-5-24(2,14(25)8-16(29)26(15,21(11)33)22(17)34)10-35-23-20(32)19(31)18(30)13(9-27)36-23/h11-20,22-23,27-32,34H,4-10H2,1-3H3/t11-,12+,13-,14-,15+,16-,17-,18-,19+,20-,22-,23-,24-,25-,26+/m1/s1

> <INCHI_KEY>
JQJBEHOGHZETSG-IWHWUFCXSA-N

> <FORMULA>
C26H42O10

> <MOLECULAR_WEIGHT>
514.612

> <EXACT_MASS>
514.277797552

> <JCHEM_ACCEPTOR_COUNT>
10

> <JCHEM_ATOM_COUNT>
78

> <JCHEM_AVERAGE_POLARIZABILITY>
54.63214258756111

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
7

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(1R,2R,4S,5S,9R,10S,12S,13R,14R,16R)-2,12,16-trihydroxy-5,9,14-trimethyl-5-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)tetracyclo[11.2.1.0^{1,10}.0^{4,9}]hexadecan-15-one

> <JCHEM_LOGP>
-1.2279692093333336

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
13.103277055788979

> <JCHEM_PKA_STRONGEST_ACIDIC>
12.198434666687909

> <JCHEM_PKA_STRONGEST_BASIC>
-2.8726307592930507

> <JCHEM_POLAR_SURFACE_AREA>
177.14

> <JCHEM_REFRACTIVITY>
125.30069999999996

> <JCHEM_ROTATABLE_BOND_COUNT>
4

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
(1R,2R,4S,5S,9R,10S,12S,13R,14R,16R)-2,12,16-trihydroxy-5,9,14-trimethyl-5-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)tetracyclo[11.2.1.0^{1,10}.0^{4,9}]hexadecan-15-one

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 04-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   04-SEP-22         0                                  
HETATM    1  C   UNK     0       0.081  -0.006   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       1.599  -0.265   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       2.759   0.870   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0       2.503   2.388   0.000  0.00  0.00           O+0
HETATM    5  C   UNK     0       4.273   0.158   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       5.393  -1.060   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       4.939  -2.638   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       3.361  -2.938   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0       2.850  -4.390   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0       2.313  -1.709   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       3.387  -0.838   0.000  0.00  0.00           C+0
HETATM   12  O   UNK     0       4.451  -1.951   0.000  0.00  0.00           O+0
HETATM   13  C   UNK     0       6.922  -0.692   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       6.473  -2.165   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       7.963  -1.826   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       9.466  -1.491   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       9.928  -0.022   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       8.886   1.113   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      10.184   1.942   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       8.295   2.535   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0       6.768   2.734   0.000  0.00  0.00           O+0
HETATM   22  C   UNK     0       6.177   4.156   0.000  0.00  0.00           C+0
HETATM   23  O   UNK     0       4.649   4.355   0.000  0.00  0.00           O+0
HETATM   24  C   UNK     0       4.058   5.777   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       2.531   5.976   0.000  0.00  0.00           C+0
HETATM   26  O   UNK     0       1.595   4.753   0.000  0.00  0.00           O+0
HETATM   27  C   UNK     0       4.994   7.000   0.000  0.00  0.00           C+0
HETATM   28  O   UNK     0       4.403   8.422   0.000  0.00  0.00           O+0
HETATM   29  C   UNK     0       6.521   6.801   0.000  0.00  0.00           C+0
HETATM   30  O   UNK     0       7.457   8.024   0.000  0.00  0.00           O+0
HETATM   31  C   UNK     0       7.112   5.379   0.000  0.00  0.00           C+0
HETATM   32  O   UNK     0       8.640   5.180   0.000  0.00  0.00           O+0
HETATM   33  C   UNK     0       7.383   0.777   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0       6.349   1.943   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       4.839   1.628   0.000  0.00  0.00           C+0
HETATM   36  O   UNK     0       3.842   2.802   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3   10                                                  
CONECT    3    2    4    5                                                  
CONECT    4    3                                                            
CONECT    5    3    6   11   35                                             
CONECT    6    5    7   13                                                  
CONECT    7    6    8                                                       
CONECT    8    7    9   10                                                  
CONECT    9    8                                                            
CONECT   10    8    2   11                                                  
CONECT   11   10    5   12                                                  
CONECT   12   11                                                            
CONECT   13    6   14   15   33                                             
CONECT   14   13                                                            
CONECT   15   13   16                                                       
CONECT   16   15   17                                                       
CONECT   17   16   18                                                       
CONECT   18   17   19   20   33                                             
CONECT   19   18                                                            
CONECT   20   18   21                                                       
CONECT   21   20   22                                                       
CONECT   22   21   23   31                                                  
CONECT   23   22   24                                                       
CONECT   24   23   25   27                                                  
CONECT   25   24   26                                                       
CONECT   26   25                                                            
CONECT   27   24   28   29                                                  
CONECT   28   27                                                            
CONECT   29   27   30   31                                                  
CONECT   30   29                                                            
CONECT   31   29   22   32                                                  
CONECT   32   31                                                            
CONECT   33   18   13   34                                                  
CONECT   34   33   35                                                       
CONECT   35   34    5   36                                                  
CONECT   36   35                                                            
MASTER        0    0    0    0    0    0    0    0   36    0   80    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₆H₄₂O₁₀

Average Mass

514.6120 Da

Monoisotopic Mass

514.27780 Da

IUPAC Name

(1R,2R,4S,5S,9R,10S,12S,13R,14R,16R)-2,12,16-trihydroxy-5,9,14-trimethyl-5-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)tetracyclo[11.2.1.0^{1,10}.0^{4,9}]hexadecan-15-one

Traditional Name

CAS Registry Number

Not Available

SMILES

C[C@@H]1[C@H]2[C@@H](O)[C@@]3([C@H](O)C[C@@H]4[C@@](C)(CO[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)CCC[C@@]4(C)[C@@H]3C[C@@H]2O)C1=O

InChI Identifier

InChI=1S/C26H42O10/c1-11-17-12(28)7-15-25(3)6-4-5-24(2,14(25)8-16(29)26(15,21(11)33)22(17)34)10-35-23-20(32)19(31)18(30)13(9-27)36-23/h11-20,22-23,27-32,34H,4-10H2,1-3H3/t11-,12+,13-,14-,15+,16-,17-,18-,19+,20-,22-,23-,24-,25-,26+/m1/s1

InChI Key

JQJBEHOGHZETSG-IWHWUFCXSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Isodon albopilosus	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as diterpene glycosides. These are diterpenoids in which an isoprene unit is glycosylated.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Terpene glycosides

Direct Parent

Diterpene glycosides

Alternative Parents

Substituents

Diterpene glycoside
Diterpenoid
Kaurane diterpenoid
Hexose monosaccharide
Glycosyl compound
O-glycosyl compound
Oxane
Monosaccharide
Cyclic alcohol
Secondary alcohol
Ketone
Organoheterocyclic compound
Polyol
Oxacycle
Acetal
Primary alcohol
Hydrocarbon derivative
Organic oxide
Organic oxygen compound
Alcohol
Carbonyl group
Organooxygen compound
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	-1.2	ChemAxon
pKa (Strongest Acidic)	12.2	ChemAxon
pKa (Strongest Basic)	-2.9	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	10	ChemAxon
Hydrogen Donor Count	7	ChemAxon
Polar Surface Area	177.14 Å²	ChemAxon
Rotatable Bond Count	4	ChemAxon
Refractivity	125.3 m³·mol⁻¹	ChemAxon
Polarizability	54.63 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

C00042216

Chemspider ID

9895180

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

11720463

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for (1r,2r,4s,5s,9r,10s,12s,13r,14r,16r)-2,12,16-trihydroxy-5,9,14-trimethyl-5-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)tetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecan-15-one (NP0200267)

MOL for NP0200267 ((1r,2r,4s,5s,9r,10s,12s,13r,14r,16r)-2,12,16-trihydroxy-5,9,14-trimethyl-5-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)tetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecan-15-one)

3D MOL for NP0200267 ((1r,2r,4s,5s,9r,10s,12s,13r,14r,16r)-2,12,16-trihydroxy-5,9,14-trimethyl-5-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)tetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecan-15-one)

3D SDF for NP0200267 ((1r,2r,4s,5s,9r,10s,12s,13r,14r,16r)-2,12,16-trihydroxy-5,9,14-trimethyl-5-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)tetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecan-15-one)

3D-SDF for NP0200267 ((1r,2r,4s,5s,9r,10s,12s,13r,14r,16r)-2,12,16-trihydroxy-5,9,14-trimethyl-5-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)tetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecan-15-one)

PDB for NP0200267 ((1r,2r,4s,5s,9r,10s,12s,13r,14r,16r)-2,12,16-trihydroxy-5,9,14-trimethyl-5-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)tetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecan-15-one)

3D PDB for NP0200267 ((1r,2r,4s,5s,9r,10s,12s,13r,14r,16r)-2,12,16-trihydroxy-5,9,14-trimethyl-5-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)tetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecan-15-one)

SMILES for NP0200267 ((1r,2r,4s,5s,9r,10s,12s,13r,14r,16r)-2,12,16-trihydroxy-5,9,14-trimethyl-5-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)tetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecan-15-one)

INCHI for NP0200267 ((1r,2r,4s,5s,9r,10s,12s,13r,14r,16r)-2,12,16-trihydroxy-5,9,14-trimethyl-5-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)tetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecan-15-one)

Structure for NP0200267 ((1r,2r,4s,5s,9r,10s,12s,13r,14r,16r)-2,12,16-trihydroxy-5,9,14-trimethyl-5-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)tetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecan-15-one)

3D Structure for NP0200267 ((1r,2r,4s,5s,9r,10s,12s,13r,14r,16r)-2,12,16-trihydroxy-5,9,14-trimethyl-5-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)tetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecan-15-one)