NP-MRD: Showing NP-Card for 5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-4-yl acetate (NP0190975)

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Record Information

Version

2.0

Created at

2022-09-04 07:45:42 UTC

Updated at

2022-09-04 07:45:42 UTC

NP-MRD ID

NP0190975

Secondary Accession Numbers

None

Natural Product Identification

Common Name

5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-4-yl acetate

Description

5-{4,10-Dihydroxy-7,9-dimethoxy-3-methyl-1H,3H,4H-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1H,3H,4H-naphtho[2,3-c]pyran-4-yl acetate belongs to the class of organic compounds known as arylnaphthalene lignans. These are lignans containing the arylnaphthalene skeleton, especially 9-(2H-1,3-benzodioxol-5-yl)-1H,3H-naphtho[2,3-c]furan-1-one or a derivative thereof. Arylnaphthalene lignans occur in nature and exhibit diverse biological activities. 5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-4-yl acetate is found in Blackwellomyces pseudomilitaris. 5-{4,10-Dihydroxy-7,9-dimethoxy-3-methyl-1H,3H,4H-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1H,3H,4H-naphtho[2,3-c]pyran-4-yl acetate is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004241502052D          

 45 50  0  0  0  0            999 V2000
    0.0422    1.3573    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5236    0.9571    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4711    1.3573    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4711    2.1823    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
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    2.1856    3.4198    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4711    3.8323    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
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M  END

     RDKit          3D

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M  END


  Mrv1533004241502052D          

 45 50  0  0  0  0            999 V2000
    0.0422    1.3573    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5236    0.9571    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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    2.9000    2.1823    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6145    2.5948    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6145    3.4198    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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    5.0435    2.5948    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7579    2.1823    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.7579    1.3573    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4724    0.9448    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0435    0.9448    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0435    0.1198    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.3290    1.3573    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6145    0.9448    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6145    0.1198    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1665   -0.4933    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9735   -0.3217    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2285    0.4629    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.0354    0.6344    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.5875    0.0213    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.2904    1.4190    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5255   -0.9348    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3325   -0.7633    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2706   -1.7194    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.4636   -1.8910    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9116   -1.2779    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1046   -1.4494    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8497   -2.2340    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.5526   -0.8363    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7456   -1.0078    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4907   -1.7925    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.6837   -1.9640    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1936   -0.3947    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4485    0.3899    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8965    1.0030    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0895    0.8314    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2555    0.5614    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8075   -0.0517    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9000    1.3573    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1856    0.9448    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  5  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
  9 11  2  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 14 16  1  0  0  0  0
 16 17  1  0  0  0  0
 16 18  1  0  0  0  0
 11 18  1  0  0  0  0
 18 19  2  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  2  0  0  0  0
 24 26  1  0  0  0  0
 22 27  1  0  0  0  0
 27 28  1  0  0  0  0
 27 29  1  0  0  0  0
 29 30  1  0  0  0  0
 30 31  1  0  0  0  0
 21 31  2  0  0  0  0
 31 32  1  0  0  0  0
 32 33  1  0  0  0  0
 32 34  2  0  0  0  0
 34 35  1  0  0  0  0
 35 36  1  0  0  0  0
 36 37  1  0  0  0  0
 35 38  2  0  0  0  0
 38 39  1  0  0  0  0
 39 40  1  0  0  0  0
 40 41  1  0  0  0  0
 39 42  2  0  0  0  0
 42 43  1  0  0  0  0
 20 43  2  0  0  0  0
 34 43  1  0  0  0  0
 19 44  1  0  0  0  0
  8 44  1  0  0  0  0
 44 45  2  0  0  0  0
  3 45  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0190975

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC1=CC(OC)=C2C(O)=C3COC(C)C(O)C3=C(C2=C1)C1=C2C=C(OC)C=C(OC)C2=C(O)C2=C1C(OC(C)=O)C(C)OC2

> <INCHI_IDENTIFIER>
InChI=1S/C34H36O11/c1-14-31(36)29-21(12-43-14)32(37)25-19(8-17(39-4)10-23(25)41-6)27(29)28-20-9-18(40-5)11-24(42-7)26(20)33(38)22-13-44-15(2)34(30(22)28)45-16(3)35/h8-11,14-15,31,34,36-38H,12-13H2,1-7H3

> <INCHI_KEY>
UIXDBHLNQHECCU-UHFFFAOYSA-N

> <FORMULA>
C34H36O11

> <MOLECULAR_WEIGHT>
620.651

> <EXACT_MASS>
620.225761979

> <JCHEM_ACCEPTOR_COUNT>
10

> <JCHEM_ATOM_COUNT>
81

> <JCHEM_AVERAGE_POLARIZABILITY>
63.82601938669158

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
3

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1H,3H,4H-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1H,3H,4H-naphtho[2,3-c]pyran-4-yl acetate

> <ALOGPS_LOGP>
3.73

> <JCHEM_LOGP>
3.6292226363333326

> <ALOGPS_LOGS>
-4.56

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
6

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
8.572532624739475

> <JCHEM_PKA_STRONGEST_ACIDIC>
7.889932532483835

> <JCHEM_PKA_STRONGEST_BASIC>
-3.4948973929507607

> <JCHEM_POLAR_SURFACE_AREA>
142.37

> <JCHEM_REFRACTIVITY>
164.06669999999997

> <JCHEM_ROTATABLE_BOND_COUNT>
6

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
1.72e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1H,3H,4H-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1H,3H,4H-naphtho[2,3-c]pyran-4-yl acetate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 24-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   24-APR-15         0                                  
HETATM    1  C   UNK     0       0.079   2.534   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0       0.977   1.786   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0       2.746   2.534   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       2.746   4.074   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       4.080   4.844   0.000  0.00  0.00           C+0
HETATM    6  O   UNK     0       4.080   6.384   0.000  0.00  0.00           O+0
HETATM    7  C   UNK     0       2.746   7.154   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       5.413   4.074   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       6.747   4.844   0.000  0.00  0.00           C+0
HETATM   10  O   UNK     0       6.747   6.384   0.000  0.00  0.00           O+0
HETATM   11  C   UNK     0       8.081   4.074   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       9.414   4.844   0.000  0.00  0.00           C+0
HETATM   13  O   UNK     0      10.748   4.074   0.000  0.00  0.00           O+0
HETATM   14  C   UNK     0      10.748   2.534   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0      12.082   1.764   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       9.414   1.764   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0       9.414   0.224   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0       8.081   2.534   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       6.747   1.764   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       6.747   0.224   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       7.778  -0.921   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       9.284  -0.601   0.000  0.00  0.00           C+0
HETATM   23  O   UNK     0       9.760   0.864   0.000  0.00  0.00           O+0
HETATM   24  C   UNK     0      11.266   1.184   0.000  0.00  0.00           C+0
HETATM   25  O   UNK     0      12.297   0.040   0.000  0.00  0.00           O+0
HETATM   26  C   UNK     0      11.742   2.649   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0      10.314  -1.745   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0      11.821  -1.425   0.000  0.00  0.00           C+0
HETATM   29  O   UNK     0       9.838  -3.210   0.000  0.00  0.00           O+0
HETATM   30  C   UNK     0       8.332  -3.530   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       7.302  -2.385   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       5.795  -2.706   0.000  0.00  0.00           C+0
HETATM   33  O   UNK     0       5.319  -4.170   0.000  0.00  0.00           O+0
HETATM   34  C   UNK     0       4.765  -1.561   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       3.259  -1.881   0.000  0.00  0.00           C+0
HETATM   36  O   UNK     0       2.783  -3.346   0.000  0.00  0.00           O+0
HETATM   37  C   UNK     0       1.276  -3.666   0.000  0.00  0.00           C+0
HETATM   38  C   UNK     0       2.228  -0.737   0.000  0.00  0.00           C+0
HETATM   39  C   UNK     0       2.704   0.728   0.000  0.00  0.00           C+0
HETATM   40  O   UNK     0       1.673   1.872   0.000  0.00  0.00           O+0
HETATM   41  C   UNK     0       0.167   1.552   0.000  0.00  0.00           C+0
HETATM   42  C   UNK     0       4.210   1.048   0.000  0.00  0.00           C+0
HETATM   43  C   UNK     0       5.241  -0.096   0.000  0.00  0.00           C+0
HETATM   44  C   UNK     0       5.413   2.534   0.000  0.00  0.00           C+0
HETATM   45  C   UNK     0       4.080   1.764   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4   45                                                  
CONECT    4    3    5                                                       
CONECT    5    4    6    8                                                  
CONECT    6    5    7                                                       
CONECT    7    6                                                            
CONECT    8    5    9   44                                                  
CONECT    9    8   10   11                                                  
CONECT   10    9                                                            
CONECT   11    9   12   18                                                  
CONECT   12   11   13                                                       
CONECT   13   12   14                                                       
CONECT   14   13   15   16                                                  
CONECT   15   14                                                            
CONECT   16   14   17   18                                                  
CONECT   17   16                                                            
CONECT   18   16   11   19                                                  
CONECT   19   18   20   44                                                  
CONECT   20   19   21   43                                                  
CONECT   21   20   22   31                                                  
CONECT   22   21   23   27                                                  
CONECT   23   22   24                                                       
CONECT   24   23   25   26                                                  
CONECT   25   24                                                            
CONECT   26   24                                                            
CONECT   27   22   28   29                                                  
CONECT   28   27                                                            
CONECT   29   27   30                                                       
CONECT   30   29   31                                                       
CONECT   31   30   21   32                                                  
CONECT   32   31   33   34                                                  
CONECT   33   32                                                            
CONECT   34   32   35   43                                                  
CONECT   35   34   36   38                                                  
CONECT   36   35   37                                                       
CONECT   37   36                                                            
CONECT   38   35   39                                                       
CONECT   39   38   40   42                                                  
CONECT   40   39   41                                                       
CONECT   41   40                                                            
CONECT   42   39   43                                                       
CONECT   43   42   20   34                                                  
CONECT   44   19    8   45                                                  
CONECT   45   44    3                                                       
MASTER        0    0    0    0    0    0    0    0   45    0  100    0
END

View in JSmol

Synonyms

Value	Source
5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1H,3H,4H-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1H,3H,4H-naphtho[2,3-c]pyran-4-yl acetic acid	Generator

Chemical Formula

C₃₄H₃₆O₁₁

Average Mass

620.6510 Da

Monoisotopic Mass

620.22576 Da

IUPAC Name

5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1H,3H,4H-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1H,3H,4H-naphtho[2,3-c]pyran-4-yl acetate

Traditional Name

5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1H,3H,4H-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1H,3H,4H-naphtho[2,3-c]pyran-4-yl acetate

CAS Registry Number

Not Available

SMILES

COC1=CC(OC)=C2C(O)=C3COC(C)C(O)C3=C(C2=C1)C1=C2C=C(OC)C=C(OC)C2=C(O)C2=C1C(OC(C)=O)C(C)OC2

InChI Identifier

InChI=1S/C34H36O11/c1-14-31(36)29-21(12-43-14)32(37)25-19(8-17(39-4)10-23(25)41-6)27(29)28-20-9-18(40-5)11-24(42-7)26(20)33(38)22-13-44-15(2)34(30(22)28)45-16(3)35/h8-11,14-15,31,34,36-38H,12-13H2,1-7H3

InChI Key

UIXDBHLNQHECCU-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Blackwellomyces pseudomilitaris	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as arylnaphthalene lignans. These are lignans containing the arylnaphthalene skeleton, especially 9-(2H-1,3-benzodioxol-5-yl)-1H,3H-naphtho[2,3-c]furan-1-one or a derivative thereof. Arylnaphthalene lignans occur in nature and exhibit diverse biological activities.

Kingdom

Organic compounds

Super Class

Lignans, neolignans and related compounds

Class

Arylnaphthalene lignans

Sub Class

Not Available

Direct Parent

Arylnaphthalene lignans

Alternative Parents

Substituents

Arylnaphthalene lignan skeleton
Biphenol
Naphthopyran
1-naphthol
Benzopyran
Isochromane
2-benzopyran
Naphthalene
Anisole
Alkyl aryl ether
Benzenoid
Pyran
Secondary alcohol
Carboxylic acid ester
Ether
Dialkyl ether
Carboxylic acid derivative
Organoheterocyclic compound
Oxacycle
Monocarboxylic acid or derivatives
Organic oxygen compound
Carbonyl group
Alcohol
Hydrocarbon derivative
Organic oxide
Organooxygen compound
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	3.73	ALOGPS
logP	3.63	ChemAxon
logS	-4.6	ALOGPS
pKa (Strongest Acidic)	7.89	ChemAxon
pKa (Strongest Basic)	-3.5	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	10	ChemAxon
Hydrogen Donor Count	3	ChemAxon
Polar Surface Area	142.37 Å²	ChemAxon
Rotatable Bond Count	6	ChemAxon
Refractivity	164.07 m³·mol⁻¹	ChemAxon
Polarizability	63.83 Å³	ChemAxon
Number of Rings	6	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

10009031

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-4-yl acetate (NP0190975)

MOL for NP0190975 (5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-4-yl acetate)

3D MOL for NP0190975 (5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-4-yl acetate)

3D SDF for NP0190975 (5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-4-yl acetate)

3D-SDF for NP0190975 (5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-4-yl acetate)

PDB for NP0190975 (5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-4-yl acetate)

3D PDB for NP0190975 (5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-4-yl acetate)

SMILES for NP0190975 (5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-4-yl acetate)

INCHI for NP0190975 (5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-4-yl acetate)

Structure for NP0190975 (5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-4-yl acetate)

3D Structure for NP0190975 (5-{4,10-dihydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-5-yl}-10-hydroxy-7,9-dimethoxy-3-methyl-1h,3h,4h-naphtho[2,3-c]pyran-4-yl acetate)