NP-MRD: Showing NP-Card for (6r)-6-hydroxy-3-methoxy-6-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-7,8-dihydro-5h-anthracene-9,10-dione (NP0189346)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-04 05:49:04 UTC

Updated at

2022-09-04 05:49:04 UTC

NP-MRD ID

NP0189346

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(6r)-6-hydroxy-3-methoxy-6-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-7,8-dihydro-5h-anthracene-9,10-dione

Description

(2R)-2-hydroxy-7-methoxy-2-methyl-5-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-1,2,3,4,9,10-hexahydroanthracene-9,10-dione belongs to the class of organic compounds known as hydroxyanthraquinones. Hydroxyanthraquinones are compounds containing a hydroxyanthraquinone moiety, which consists of an anthracene bearing a quinone, and hydroxyl group. (6r)-6-hydroxy-3-methoxy-6-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-7,8-dihydro-5h-anthracene-9,10-dione is found in Cortinarius persplendidus. Based on a literature review very few articles have been published on (2R)-2-hydroxy-7-methoxy-2-methyl-5-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-1,2,3,4,9,10-hexahydroanthracene-9,10-dione.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309042207492D          

 43 47  0  0  1  0            999 V2000
    5.0013    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -1.6500    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.0013   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -1.6500    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.4302   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.8592   -1.2375    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    7.8592   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.5737   -0.0000    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    8.5737    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.2881    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.2881   -0.4125    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   10.0026   -0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.2881   -1.2375    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   10.0026   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.5737   -1.6500    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    8.5737   -2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -2.4750    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.4302   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -2.8875    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.0013   -3.7125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -2.4750    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.5724   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.8250    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.8125    0.6817    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2822    1.6002    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  7  6  1  6  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  6  0  0  0
 10 11  1  0  0  0  0
 12 11  1  6  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  6  0  0  0
 15 16  1  0  0  0  0
 14 17  1  0  0  0  0
 17 18  1  1  0  0  0
 17 19  1  0  0  0  0
 19 20  1  6  0  0  0
 19 21  1  0  0  0  0
 12 21  1  0  0  0  0
 21 22  1  1  0  0  0
  9 23  1  0  0  0  0
 23 24  1  1  0  0  0
 23 25  1  0  0  0  0
 25 26  1  6  0  0  0
 25 27  1  0  0  0  0
  7 27  1  0  0  0  0
 27 28  1  1  0  0  0
  5 29  2  0  0  0  0
 29 30  1  0  0  0  0
 30 31  2  0  0  0  0
  3 31  1  0  0  0  0
 30 32  1  0  0  0  0
 32 33  2  0  0  0  0
 32 34  1  0  0  0  0
 34 35  2  0  0  0  0
 35 36  1  0  0  0  0
 36 37  1  0  0  0  0
 37 38  1  0  0  0  0
 38 39  1  6  0  0  0
 38 40  1  1  0  0  0
 38 41  1  0  0  0  0
 34 41  1  0  0  0  0
 35 42  1  0  0  0  0
 29 42  1  0  0  0  0
 42 43  2  0  0  0  0
M  END

     RDKit          3D

 79 83  0  0  0  0  0  0  0  0999 V2000
   -3.5044   -5.9741    0.3099 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4664   -4.9854    0.1123 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1854   -3.6203    0.1509 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9232   -3.1868    0.3907 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6143   -1.8137    0.4345 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3927   -1.4689    0.6679 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1815   -1.0671    0.8977 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.6474   -1.4396   -0.2252 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8871   -0.7823    0.0345 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.4966   -0.4627   -1.3116 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6187    0.1803   -1.3415 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8312   -0.0524   -0.9262 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.1078    0.8790    0.1073 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.4241    0.9736    0.4444 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.4781    1.8470    1.7084 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9512    3.0969    1.4720 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.1228    1.7637   -0.6302 C   0  0  1  0  0  0  0  0  0  0  0  0
    8.4579    1.4178   -0.7671 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.4203    1.4795   -1.9659 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.3686    2.3682   -2.1832 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.9670    0.0411   -1.9047 C   0  0  1  0  0  0  0  0  0  0  0  0
    7.0559   -0.7130   -1.4685 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6577   -1.7137    0.8965 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.4870   -1.0845    1.8273 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.6662   -2.5264    1.7309 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.1797   -3.6279    1.0324 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.4928   -1.6666    2.1476 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.9359   -0.6980    3.0231 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6562   -0.9042    0.2216 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9200   -1.3587   -0.0183 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1793   -2.7100   -0.0525 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9865   -0.3913   -0.2324 C   0  0  0  0  0  0  0  0  0  0  0  0
   -7.1595   -0.7412   -0.4554 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6947    1.0624   -0.1888 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4881    1.5283    0.0395 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1415    2.9805    0.0936 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3241    3.8681   -0.0435 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.2665    3.2445   -1.0745 C   0  0  1  0  0  0  0  0  0  0  0  0
   -7.3571    4.2449   -1.3705 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5531    2.8742   -2.1892 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.8370    2.0131   -0.4126 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4153    0.5311    0.2550 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2828    0.9856    0.4690 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3154   -6.1956    1.3700 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8656   -6.9368   -0.1584 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5299   -5.7727   -0.1739 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1068   -3.9156    0.5581 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.0758    0.0323    0.9892 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6907    0.1379    0.6256 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6980    0.2120   -1.7874 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.3823   -1.3772   -1.9520 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.9456   -1.0393   -0.4326 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.9209    0.0424    0.7263 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.4890    1.8577    2.1215 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.8290    1.2972    2.4421 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.9852    2.9859    1.2769 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.9698    2.8443   -0.4395 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.7732    1.6212   -1.7026 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.1279    1.6493   -2.8090 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.9004    2.6623   -1.3811 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.7226   -0.3688   -2.9023 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.7524   -1.6558   -1.3229 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2241   -2.4497    0.3103 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.9943   -1.7912    2.2968 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1403   -2.9046    2.6556 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6265   -3.6326    0.1422 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2586   -2.3046    2.6281 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.7644   -0.9830    3.4717 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1882   -3.0399   -0.2453 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4206    3.2416   -0.7162 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6068    3.1662    1.0487 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.0017    4.8389   -0.4411 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8321    3.9716    0.9255 H   0  0  0  0  0  0  0  0  0  0  0  0
   -8.1430    3.7914   -1.9777 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.9211    5.0867   -1.9431 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.7563    4.5793   -0.3826 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9711    2.1181   -2.7018 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.2042    2.3121    0.5963 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.6153    1.5282   -1.0312 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  2  0
  4  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  8  9  1  0
  9 10  1  0
 10 11  1  0
 11 12  1  0
 12 13  1  0
 13 14  1  0
 14 15  1  0
 15 16  1  0
 14 17  1  0
 17 18  1  0
 17 19  1  0
 19 20  1  0
 19 21  1  0
 21 22  1  0
  9 23  1  0
 23 24  1  0
 23 25  1  0
 25 26  1  0
 25 27  1  0
 27 28  1  0
  5 29  2  0
 29 42  1  0
 42 43  2  0
 42 35  1  0
 35 34  2  0
 34 41  1  0
 41 38  1  0
 38 39  1  0
 38 40  1  6
 38 37  1  0
 37 36  1  0
 34 32  1  0
 32 33  2  0
 32 30  1  0
 30 31  2  0
 31  3  1  0
 27  7  1  0
 30 29  1  0
 21 12  1  0
 36 35  1  0
  1 44  1  0
  1 45  1  0
  1 46  1  0
  4 47  1  0
  7 48  1  1
  9 49  1  1
 10 50  1  0
 10 51  1  0
 12 52  1  1
 14 53  1  1
 15 54  1  0
 15 55  1  0
 16 56  1  0
 17 57  1  1
 18 58  1  0
 19 59  1  6
 20 60  1  0
 21 61  1  6
 22 62  1  0
 23 63  1  6
 24 64  1  0
 25 65  1  1
 26 66  1  0
 27 67  1  1
 28 68  1  0
 41 78  1  0
 41 79  1  0
 39 74  1  0
 39 75  1  0
 39 76  1  0
 40 77  1  0
 37 72  1  0
 37 73  1  0
 36 70  1  0
 36 71  1  0
 31 69  1  0
M  END


  Mrv1652309042207492D          

 43 47  0  0  1  0            999 V2000
    5.0013    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -1.6500    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.0013   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -1.6500    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.4302   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.8592   -1.2375    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    7.8592   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.5737   -0.0000    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    8.5737    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.2881    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.2881   -0.4125    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   10.0026   -0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.2881   -1.2375    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   10.0026   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.5737   -1.6500    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    8.5737   -2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -2.4750    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.4302   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -2.8875    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.0013   -3.7125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -2.4750    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.5724   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.8250    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.8125    0.6817    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2822    1.6002    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  7  6  1  6  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  6  0  0  0
 10 11  1  0  0  0  0
 12 11  1  6  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  6  0  0  0
 15 16  1  0  0  0  0
 14 17  1  0  0  0  0
 17 18  1  1  0  0  0
 17 19  1  0  0  0  0
 19 20  1  6  0  0  0
 19 21  1  0  0  0  0
 12 21  1  0  0  0  0
 21 22  1  1  0  0  0
  9 23  1  0  0  0  0
 23 24  1  1  0  0  0
 23 25  1  0  0  0  0
 25 26  1  6  0  0  0
 25 27  1  0  0  0  0
  7 27  1  0  0  0  0
 27 28  1  1  0  0  0
  5 29  2  0  0  0  0
 29 30  1  0  0  0  0
 30 31  2  0  0  0  0
  3 31  1  0  0  0  0
 30 32  1  0  0  0  0
 32 33  2  0  0  0  0
 32 34  1  0  0  0  0
 34 35  2  0  0  0  0
 35 36  1  0  0  0  0
 36 37  1  0  0  0  0
 37 38  1  0  0  0  0
 38 39  1  6  0  0  0
 38 40  1  1  0  0  0
 38 41  1  0  0  0  0
 34 41  1  0  0  0  0
 35 42  1  0  0  0  0
 29 42  1  0  0  0  0
 42 43  2  0  0  0  0
M  END
> <DATABASE_ID>
NP0189346

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC1=CC(O[C@@H]2O[C@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O)=C2C(=O)C3=C(C[C@](C)(O)CC3)C(=O)C2=C1

> <INCHI_IDENTIFIER>
InChI=1S/C28H36O15/c1-28(38)4-3-11-13(7-28)18(30)12-5-10(39-2)6-14(17(12)19(11)31)41-27-25(37)23(35)21(33)16(43-27)9-40-26-24(36)22(34)20(32)15(8-29)42-26/h5-6,15-16,20-27,29,32-38H,3-4,7-9H2,1-2H3/t15-,16-,20-,21-,22+,23+,24-,25-,26-,27-,28-/m1/s1

> <INCHI_KEY>
REOONKSLIIFQGV-DPOJXMLXSA-N

> <FORMULA>
C28H36O15

> <MOLECULAR_WEIGHT>
612.581

> <EXACT_MASS>
612.205420459

> <JCHEM_ACCEPTOR_COUNT>
15

> <JCHEM_ATOM_COUNT>
79

> <JCHEM_AVERAGE_POLARIZABILITY>
60.544358202960446

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
8

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2R)-2-hydroxy-7-methoxy-2-methyl-5-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-1,2,3,4,9,10-hexahydroanthracene-9,10-dione

> <JCHEM_LOGP>
-2.895451828333334

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
12.42721762108216

> <JCHEM_PKA_STRONGEST_ACIDIC>
11.904897133352517

> <JCHEM_PKA_STRONGEST_BASIC>
-2.8173885036682638

> <JCHEM_POLAR_SURFACE_AREA>
242.12999999999997

> <JCHEM_REFRACTIVITY>
141.6067

> <JCHEM_ROTATABLE_BOND_COUNT>
7

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
(6R)-6-hydroxy-3-methoxy-6-methyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-7,8-dihydro-5H-anthracene-9,10-dione

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 04-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   04-SEP-22         0                                  
HETATM    1  C   UNK     0       9.336   3.850   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0       9.336   2.310   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0       8.002   1.540   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       8.002  -0.000   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       6.668  -0.770   0.000  0.00  0.00           C+0
HETATM    6  O   UNK     0       6.668  -2.310   0.000  0.00  0.00           O+0
HETATM    7  C   UNK     0       8.002  -3.080   0.000  0.00  0.00           C+0
HETATM    8  O   UNK     0       9.336  -2.310   0.000  0.00  0.00           O+0
HETATM    9  C   UNK     0      10.669  -3.080   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      12.003  -2.310   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0      13.337  -3.080   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0      14.670  -2.310   0.000  0.00  0.00           C+0
HETATM   13  O   UNK     0      14.670  -0.770   0.000  0.00  0.00           O+0
HETATM   14  C   UNK     0      16.004  -0.000   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0      16.004   1.540   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0      17.338   2.310   0.000  0.00  0.00           O+0
HETATM   17  C   UNK     0      17.338  -0.770   0.000  0.00  0.00           C+0
HETATM   18  O   UNK     0      18.672  -0.000   0.000  0.00  0.00           O+0
HETATM   19  C   UNK     0      17.338  -2.310   0.000  0.00  0.00           C+0
HETATM   20  O   UNK     0      18.672  -3.080   0.000  0.00  0.00           O+0
HETATM   21  C   UNK     0      16.004  -3.080   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0      16.004  -4.620   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0      10.669  -4.620   0.000  0.00  0.00           C+0
HETATM   24  O   UNK     0      12.003  -5.390   0.000  0.00  0.00           O+0
HETATM   25  C   UNK     0       9.336  -5.390   0.000  0.00  0.00           C+0
HETATM   26  O   UNK     0       9.336  -6.930   0.000  0.00  0.00           O+0
HETATM   27  C   UNK     0       8.002  -4.620   0.000  0.00  0.00           C+0
HETATM   28  O   UNK     0       6.668  -5.390   0.000  0.00  0.00           O+0
HETATM   29  C   UNK     0       5.335  -0.000   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       5.335   1.540   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       6.668   2.310   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       4.001   2.310   0.000  0.00  0.00           C+0
HETATM   33  O   UNK     0       4.001   3.850   0.000  0.00  0.00           O+0
HETATM   34  C   UNK     0       2.667   1.540   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       2.667   0.000   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0       1.334  -0.770   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0       0.000  -0.000   0.000  0.00  0.00           C+0
HETATM   38  C   UNK     0       0.000   1.540   0.000  0.00  0.00           C+0
HETATM   39  C   UNK     0      -1.517   1.273   0.000  0.00  0.00           C+0
HETATM   40  O   UNK     0      -0.527   2.987   0.000  0.00  0.00           O+0
HETATM   41  C   UNK     0       1.334   2.310   0.000  0.00  0.00           C+0
HETATM   42  C   UNK     0       4.001  -0.770   0.000  0.00  0.00           C+0
HETATM   43  O   UNK     0       4.001  -2.310   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4   31                                                  
CONECT    4    3    5                                                       
CONECT    5    4    6   29                                                  
CONECT    6    5    7                                                       
CONECT    7    6    8   27                                                  
CONECT    8    7    9                                                       
CONECT    9    8   10   23                                                  
CONECT   10    9   11                                                       
CONECT   11   10   12                                                       
CONECT   12   11   13   21                                                  
CONECT   13   12   14                                                       
CONECT   14   13   15   17                                                  
CONECT   15   14   16                                                       
CONECT   16   15                                                            
CONECT   17   14   18   19                                                  
CONECT   18   17                                                            
CONECT   19   17   20   21                                                  
CONECT   20   19                                                            
CONECT   21   19   12   22                                                  
CONECT   22   21                                                            
CONECT   23    9   24   25                                                  
CONECT   24   23                                                            
CONECT   25   23   26   27                                                  
CONECT   26   25                                                            
CONECT   27   25    7   28                                                  
CONECT   28   27                                                            
CONECT   29    5   30   42                                                  
CONECT   30   29   31   32                                                  
CONECT   31   30    3                                                       
CONECT   32   30   33   34                                                  
CONECT   33   32                                                            
CONECT   34   32   35   41                                                  
CONECT   35   34   36   42                                                  
CONECT   36   35   37                                                       
CONECT   37   36   38                                                       
CONECT   38   37   39   40   41                                             
CONECT   39   38                                                            
CONECT   40   38                                                            
CONECT   41   38   34                                                       
CONECT   42   35   29   43                                                  
CONECT   43   42                                                            
MASTER        0    0    0    0    0    0    0    0   43    0   94    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₈H₃₆O₁₅

Average Mass

612.5810 Da

Monoisotopic Mass

612.20542 Da

IUPAC Name

Traditional Name

(6R)-6-hydroxy-3-methoxy-6-methyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-7,8-dihydro-5H-anthracene-9,10-dione

CAS Registry Number

Not Available

SMILES

COC1=CC(O[C@@H]2O[C@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O)=C2C(=O)C3=C(C[C@](C)(O)CC3)C(=O)C2=C1

InChI Identifier

InChI=1S/C28H36O15/c1-28(38)4-3-11-13(7-28)18(30)12-5-10(39-2)6-14(17(12)19(11)31)41-27-25(37)23(35)21(33)16(43-27)9-40-26-24(36)22(34)20(32)15(8-29)42-26/h5-6,15-16,20-27,29,32-38H,3-4,7-9H2,1-2H3/t15-,16-,20-,21-,22+,23+,24-,25-,26-,27-,28-/m1/s1

InChI Key

REOONKSLIIFQGV-DPOJXMLXSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Dermocybe splendida	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as hydroxyanthraquinones. Hydroxyanthraquinones are compounds containing a hydroxyanthraquinone moiety, which consists of an anthracene bearing a quinone, and hydroxyl group.

Kingdom

Super Class

Class

Sub Class

Direct Parent

Hydroxyanthraquinones

Alternative Parents

Substituents

Hydroxyanthraquinone
Phenolic glycoside
Disaccharide
Glycosyl compound
O-glycosyl compound
Anisole
Aryl ketone
Quinone
Alkyl aryl ether
Oxane
Tertiary alcohol
Ketone
Secondary alcohol
Polyol
Acetal
Organoheterocyclic compound
Oxacycle
Ether
Primary alcohol
Organooxygen compound
Hydrocarbon derivative
Organic oxide
Organic oxygen compound
Alcohol
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	-2.9	ChemAxon
pKa (Strongest Acidic)	11.9	ChemAxon
pKa (Strongest Basic)	-2.8	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	15	ChemAxon
Hydrogen Donor Count	8	ChemAxon
Polar Surface Area	242.13 Å²	ChemAxon
Rotatable Bond Count	7	ChemAxon
Refractivity	141.61 m³·mol⁻¹	ChemAxon
Polarizability	60.54 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

163040335

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for (6r)-6-hydroxy-3-methoxy-6-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-7,8-dihydro-5h-anthracene-9,10-dione (NP0189346)

MOL for NP0189346 ((6r)-6-hydroxy-3-methoxy-6-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-7,8-dihydro-5h-anthracene-9,10-dione)

3D MOL for NP0189346 ((6r)-6-hydroxy-3-methoxy-6-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-7,8-dihydro-5h-anthracene-9,10-dione)

3D SDF for NP0189346 ((6r)-6-hydroxy-3-methoxy-6-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-7,8-dihydro-5h-anthracene-9,10-dione)

3D-SDF for NP0189346 ((6r)-6-hydroxy-3-methoxy-6-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-7,8-dihydro-5h-anthracene-9,10-dione)

PDB for NP0189346 ((6r)-6-hydroxy-3-methoxy-6-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-7,8-dihydro-5h-anthracene-9,10-dione)

3D PDB for NP0189346 ((6r)-6-hydroxy-3-methoxy-6-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-7,8-dihydro-5h-anthracene-9,10-dione)

SMILES for NP0189346 ((6r)-6-hydroxy-3-methoxy-6-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-7,8-dihydro-5h-anthracene-9,10-dione)

INCHI for NP0189346 ((6r)-6-hydroxy-3-methoxy-6-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-7,8-dihydro-5h-anthracene-9,10-dione)

Structure for NP0189346 ((6r)-6-hydroxy-3-methoxy-6-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-7,8-dihydro-5h-anthracene-9,10-dione)

3D Structure for NP0189346 ((6r)-6-hydroxy-3-methoxy-6-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-7,8-dihydro-5h-anthracene-9,10-dione)