NP-MRD: Showing NP-Card for 2-{3,9,10-trihydroxy-3a,5a,5b,8,8,11a-hexamethyl-1h,2h,4h,5h,6h,7h,7ah,9h,10h,11h,11bh,12h,13bh-cyclopenta[a]chrysen-3-yl}propanoic acid (NP0186115)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-04 01:49:08 UTC

Updated at

2022-09-04 01:49:08 UTC

NP-MRD ID

NP0186115

Secondary Accession Numbers

None

Natural Product Identification

Common Name

2-{3,9,10-trihydroxy-3a,5a,5b,8,8,11a-hexamethyl-1h,2h,4h,5h,6h,7h,7ah,9h,10h,11h,11bh,12h,13bh-cyclopenta[a]chrysen-3-yl}propanoic acid

Description

2-{6,16,17-Trihydroxy-1,2,5,14,18,18-hexamethylpentacyclo[11.8.0.0²,¹⁰.0⁵,⁹.0¹⁴,¹⁹]Henicos-10-en-6-yl}propanoic acid belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units. 2-{3,9,10-trihydroxy-3a,5a,5b,8,8,11a-hexamethyl-1h,2h,4h,5h,6h,7h,7ah,9h,10h,11h,11bh,12h,13bh-cyclopenta[a]chrysen-3-yl}propanoic acid is found in Crotalaria emarginella. 2-{6,16,17-Trihydroxy-1,2,5,14,18,18-hexamethylpentacyclo[11.8.0.0²,¹⁰.0⁵,⁹.0¹⁴,¹⁹]Henicos-10-en-6-yl}propanoic acid is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004171520172D          

 35 39  0  0  0  0            999 V2000
   -0.9890   -5.5676    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5657   -4.8595    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9673   -4.1388    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7922   -4.1263    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5440   -3.4307    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.2592   -4.8720    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1605   -5.6911    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.1855   -4.0503    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9442   -3.7263    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4868   -4.3477    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3117   -4.3603    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7350   -3.6521    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5599   -3.6647    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9615   -4.3853    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7864   -4.3979    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3848   -3.6772    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2097   -3.6898    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0346   -3.7023    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4580   -2.9942    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.4362   -4.4230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.2611   -4.4355    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.0129   -5.1311    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.7838   -5.4250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.8573   -5.9413    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.1880   -5.1186    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7647   -5.8267    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9398   -5.8141    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5382   -5.0935    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1149   -5.8016    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7133   -5.0809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6146   -5.9000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2900   -5.7890    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4651   -5.7765    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0635   -5.0558    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5685   -5.7158    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  3  5  1  0  0  0  0
  2  6  1  0  0  0  0
  6  7  1  0  0  0  0
  6  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
 10 11  1  0  0  0  0
 11 12  2  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 15 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
 20 22  1  0  0  0  0
 22 23  1  0  0  0  0
 22 24  1  0  0  0  0
 22 25  1  0  0  0  0
 15 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 14 28  1  0  0  0  0
 28 29  1  0  0  0  0
 28 30  1  0  0  0  0
 11 30  1  0  0  0  0
 30 31  1  0  0  0  0
 30 32  1  0  0  0  0
 32 33  1  0  0  0  0
 33 34  1  0  0  0  0
  6 34  1  0  0  0  0
 10 34  1  0  0  0  0
 34 35  1  0  0  0  0
M  END

     RDKit          3D

 83 87  0  0  0  0  0  0  0  0999 V2000
    6.4972   -0.1744   -1.3858 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9506   -0.7315   -0.1317 C   0  0  1  0  0  0  0  0  0  0  0  0
    7.0550   -0.9385    0.8571 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.3183   -2.0720    1.3292 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.8381    0.1308    1.2933 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8428   -0.0889    0.5521 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.5809   -0.8755    1.7091 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.9303    1.3180    0.9875 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5101    1.9160    0.8874 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7133    0.6400    0.8861 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.3249    0.6974    0.5432 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6172    1.8068    0.7265 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8101    1.9349    0.3987 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4409    0.6385    0.0653 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.9326    0.6087    0.3145 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.3623    0.7334    1.7121 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4786    1.8353   -0.4386 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9678    1.8280   -0.5187 C   0  0  1  0  0  0  0  0  0  0  0  0
   -5.3145    2.8503   -1.4373 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5736    0.5717   -1.0234 C   0  0  2  0  0  0  0  0  0  0  0  0
   -6.9171    0.5442   -0.6043 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9368   -0.6941   -0.5050 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6094   -1.1963    0.7104 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1896   -1.7371   -1.6130 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4373   -0.5764   -0.4356 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.7953   -1.8751   -0.1137 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4213   -1.8622    0.3938 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7296   -0.5847    0.6079 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.5472   -0.3514    2.1160 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6755   -0.5359   -0.0173 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.4989   -0.5268   -1.4899 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5523   -1.6707    0.3830 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9211   -1.4959   -0.2454 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4868   -0.1337   -0.1801 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.5475    0.6268   -1.4689 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.8850   -0.4367   -2.2722 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.4693   -0.7298   -1.5761 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.7977    0.8769   -1.3754 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.6074   -1.7802   -0.3964 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.4930    0.7092    2.0404 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.8564   -0.4048    2.5204 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.6427    1.9500    0.4364 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.1961    1.4059    2.0624 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2861    2.5587    1.7598 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3986    2.5190   -0.0179 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9640    0.1346    1.8427 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1330    2.6615    1.1427 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3735    2.5281    1.1616 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8635    2.6008   -0.5134 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3745    0.5216   -1.0619 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4799    0.8948    1.7007 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1823   -0.0966    2.3838 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9896    1.7267    2.1009 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0511    1.8553   -1.4437 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1691    2.7129    0.1633 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.4607    2.1617    0.4420 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1893    3.2547   -1.2052 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6268    0.5900   -2.1461 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.4190   -0.1615   -1.0757 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.3687   -0.4225    1.0319 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9956   -1.4387    1.5699 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.2504   -2.1104    0.5250 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5390   -1.4537   -2.4559 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.2298   -1.6004   -1.9433 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9774   -2.7535   -1.2234 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1437   -0.3454   -1.5115 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9335   -2.5352   -1.0267 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4633   -2.3948    0.6388 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3353   -2.4949    1.3321 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7967   -2.4666   -0.3356 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8960    0.6236    2.4394 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0561   -1.1477    2.7051 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5220   -0.4208    2.3963 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.4906    0.5140   -1.8563 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4280   -1.0924   -1.7877 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.3039   -1.0556   -2.0603 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2062   -2.6666   -0.0102 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6929   -1.7970    1.4545 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.6109   -2.1743    0.3419 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9600   -1.9445   -1.2817 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.4516    1.2821   -1.4356 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.5236   -0.0683   -2.3208 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.7054    1.3514   -1.5804 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  5  1  0
  3  4  2  0
  2  6  1  0
  6  7  1  1
  6  8  1  0
  8  9  1  0
  9 10  1  0
 10 11  1  0
 11 12  2  0
 12 13  1  0
 13 14  1  0
 14 15  1  0
 15 16  1  1
 15 17  1  0
 17 18  1  0
 18 19  1  0
 18 20  1  0
 20 21  1  0
 20 22  1  0
 22 23  1  0
 22 24  1  0
 22 25  1  0
 25 26  1  0
 26 27  1  0
 27 28  1  0
 28 29  1  1
 28 30  1  0
 30 31  1  6
 30 32  1  0
 32 33  1  0
 33 34  1  0
 34 35  1  6
 34  6  1  0
 34 10  1  0
 30 11  1  0
 28 14  1  0
 25 15  1  0
  1 36  1  0
  1 37  1  0
  1 38  1  0
  2 39  1  6
  5 40  1  0
  7 41  1  0
  8 42  1  0
  8 43  1  0
  9 44  1  0
  9 45  1  0
 10 46  1  1
 12 47  1  0
 13 48  1  0
 13 49  1  0
 14 50  1  6
 16 51  1  0
 16 52  1  0
 16 53  1  0
 17 54  1  0
 17 55  1  0
 18 56  1  1
 19 57  1  0
 20 58  1  6
 21 59  1  0
 23 60  1  0
 23 61  1  0
 23 62  1  0
 24 63  1  0
 24 64  1  0
 24 65  1  0
 25 66  1  6
 26 67  1  0
 26 68  1  0
 27 69  1  0
 27 70  1  0
 29 71  1  0
 29 72  1  0
 29 73  1  0
 31 74  1  0
 31 75  1  0
 31 76  1  0
 32 77  1  0
 32 78  1  0
 33 79  1  0
 33 80  1  0
 35 81  1  0
 35 82  1  0
 35 83  1  0
M  END


  Mrv1533004171520172D          

 35 39  0  0  0  0            999 V2000
   -0.9890   -5.5676    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5657   -4.8595    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9673   -4.1388    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7922   -4.1263    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5440   -3.4307    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.2592   -4.8720    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1605   -5.6911    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.1855   -4.0503    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9442   -3.7263    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4868   -4.3477    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3117   -4.3603    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7350   -3.6521    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5599   -3.6647    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9615   -4.3853    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7864   -4.3979    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3848   -3.6772    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2097   -3.6898    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0346   -3.7023    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4580   -2.9942    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.4362   -4.4230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.2611   -4.4355    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.0129   -5.1311    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.7838   -5.4250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.8573   -5.9413    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.1880   -5.1186    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7647   -5.8267    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9398   -5.8141    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5382   -5.0935    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1149   -5.8016    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7133   -5.0809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6146   -5.9000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2900   -5.7890    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4651   -5.7765    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0635   -5.0558    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5685   -5.7158    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  3  5  1  0  0  0  0
  2  6  1  0  0  0  0
  6  7  1  0  0  0  0
  6  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
 10 11  1  0  0  0  0
 11 12  2  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 15 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
 20 22  1  0  0  0  0
 22 23  1  0  0  0  0
 22 24  1  0  0  0  0
 22 25  1  0  0  0  0
 15 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 14 28  1  0  0  0  0
 28 29  1  0  0  0  0
 28 30  1  0  0  0  0
 11 30  1  0  0  0  0
 30 31  1  0  0  0  0
 30 32  1  0  0  0  0
 32 33  1  0  0  0  0
 33 34  1  0  0  0  0
  6 34  1  0  0  0  0
 10 34  1  0  0  0  0
 34 35  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0186115

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(C(O)=O)C1(O)CCC2C3=CCC4C5(C)CC(O)C(O)C(C)(C)C5CCC4(C)C3(C)CCC12C

> <INCHI_IDENTIFIER>
InChI=1S/C30H48O5/c1-17(24(33)34)30(35)13-10-19-18-8-9-22-26(4)16-20(31)23(32)25(2,3)21(26)11-12-29(22,7)27(18,5)14-15-28(19,30)6/h8,17,19-23,31-32,35H,9-16H2,1-7H3,(H,33,34)

> <INCHI_KEY>
JWQDJXFGFNQZNP-UHFFFAOYSA-N

> <FORMULA>
C30H48O5

> <MOLECULAR_WEIGHT>
488.709

> <EXACT_MASS>
488.350174646

> <JCHEM_ACCEPTOR_COUNT>
5

> <JCHEM_ATOM_COUNT>
83

> <JCHEM_AVERAGE_POLARIZABILITY>
56.172592710971486

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
4

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
2-{6,16,17-trihydroxy-1,2,5,14,18,18-hexamethylpentacyclo[11.8.0.0²,¹⁰.0⁵,⁹.0¹⁴,¹⁹]henicos-10-en-6-yl}propanoic acid

> <ALOGPS_LOGP>
4.88

> <JCHEM_LOGP>
4.247542315666667

> <ALOGPS_LOGS>
-4.81

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA>
13.521991262795922

> <JCHEM_PKA_STRONGEST_ACIDIC>
4.592099673099513

> <JCHEM_PKA_STRONGEST_BASIC>
-3.1598164618201103

> <JCHEM_POLAR_SURFACE_AREA>
97.99000000000001

> <JCHEM_REFRACTIVITY>
136.40770000000003

> <JCHEM_ROTATABLE_BOND_COUNT>
2

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
7.61e-03 g/l

> <JCHEM_TRADITIONAL_IUPAC>
2-{6,16,17-trihydroxy-1,2,5,14,18,18-hexamethylpentacyclo[11.8.0.0²,¹⁰.0⁵,⁹.0¹⁴,¹⁹]henicos-10-en-6-yl}propanoic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 17-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   17-APR-15         0                                  
HETATM    1  C   UNK     0      -1.846 -10.393   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -1.056  -9.071   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -1.806  -7.726   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0      -3.345  -7.702   0.000  0.00  0.00           O+0
HETATM    5  O   UNK     0      -1.015  -6.404   0.000  0.00  0.00           O+0
HETATM    6  C   UNK     0       0.484  -9.094   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0       0.300 -10.623   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0       0.346  -7.561   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       1.762  -6.956   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       2.775  -8.116   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       4.315  -8.139   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       5.105  -6.817   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       6.645  -6.841   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       7.395  -8.186   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       8.935  -8.209   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       8.185  -6.864   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       9.725  -6.888   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      11.265  -6.911   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0      12.055  -5.589   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0      12.014  -8.256   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0      13.554  -8.280   0.000  0.00  0.00           O+0
HETATM   22  C   UNK     0      11.224  -9.578   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      12.663 -10.127   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      10.934 -11.090   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       9.684  -9.555   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       8.894 -10.876   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       7.354 -10.853   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       6.605  -9.508   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       5.814 -10.830   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       5.065  -9.484   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       4.881 -11.013   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       4.275 -10.806   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0       2.735 -10.783   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0       1.985  -9.438   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       1.061 -10.670   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3    6                                                  
CONECT    3    2    4    5                                                  
CONECT    4    3                                                            
CONECT    5    3                                                            
CONECT    6    2    7    8   34                                             
CONECT    7    6                                                            
CONECT    8    6    9                                                       
CONECT    9    8   10                                                       
CONECT   10    9   11   34                                                  
CONECT   11   10   12   30                                                  
CONECT   12   11   13                                                       
CONECT   13   12   14                                                       
CONECT   14   13   15   28                                                  
CONECT   15   14   16   17   25                                             
CONECT   16   15                                                            
CONECT   17   15   18                                                       
CONECT   18   17   19   20                                                  
CONECT   19   18                                                            
CONECT   20   18   21   22                                                  
CONECT   21   20                                                            
CONECT   22   20   23   24   25                                             
CONECT   23   22                                                            
CONECT   24   22                                                            
CONECT   25   22   15   26                                                  
CONECT   26   25   27                                                       
CONECT   27   26   28                                                       
CONECT   28   27   14   29   30                                             
CONECT   29   28                                                            
CONECT   30   28   11   31   32                                             
CONECT   31   30                                                            
CONECT   32   30   33                                                       
CONECT   33   32   34                                                       
CONECT   34   33    6   10   35                                             
CONECT   35   34                                                            
MASTER        0    0    0    0    0    0    0    0   35    0   78    0
END

View in JSmol

Synonyms

Value	Source
2-{6,16,17-trihydroxy-1,2,5,14,18,18-hexamethylpentacyclo[11.8.0.0,.0,.0,]henicos-10-en-6-yl}propanoate	Generator
2-{6,16,17-trihydroxy-1,2,5,14,18,18-hexamethylpentacyclo[11.8.0.0²,¹⁰.0⁵,⁹.0¹⁴,¹⁹]henicos-10-en-6-yl}propanoate	Generator

Chemical Formula

C₃₀H₄₈O₅

Average Mass

488.7090 Da

Monoisotopic Mass

488.35017 Da

IUPAC Name

2-{6,16,17-trihydroxy-1,2,5,14,18,18-hexamethylpentacyclo[11.8.0.0²,¹⁰.0⁵,⁹.0¹⁴,¹⁹]henicos-10-en-6-yl}propanoic acid

Traditional Name

2-{6,16,17-trihydroxy-1,2,5,14,18,18-hexamethylpentacyclo[11.8.0.0²,¹⁰.0⁵,⁹.0¹⁴,¹⁹]henicos-10-en-6-yl}propanoic acid

CAS Registry Number

Not Available

SMILES

CC(C(O)=O)C1(O)CCC2C3=CCC4C5(C)CC(O)C(O)C(C)(C)C5CCC4(C)C3(C)CCC12C

InChI Identifier

InChI=1S/C30H48O5/c1-17(24(33)34)30(35)13-10-19-18-8-9-22-26(4)16-20(31)23(32)25(2,3)21(26)11-12-29(22,7)27(18,5)14-15-28(19,30)6/h8,17,19-23,31-32,35H,9-16H2,1-7H3,(H,33,34)

InChI Key

JWQDJXFGFNQZNP-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Crotalaria emarginella	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Triterpenoids

Direct Parent

Triterpenoids

Alternative Parents

Substituents

Triterpenoid
Hydroxy bile acid, alcohol, or derivatives
Monohydroxy bile acid, alcohol, or derivatives
Bile acid, alcohol, or derivatives
Steroid acid
17-hydroxysteroid
Hydroxysteroid
Delta-7-steroid
Steroid
Cyclic alcohol
Tertiary alcohol
Secondary alcohol
Monocarboxylic acid or derivatives
Carboxylic acid
Carboxylic acid derivative
Polyol
Hydrocarbon derivative
Organic oxide
Alcohol
Carbonyl group
Organic oxygen compound
Organooxygen compound
Aliphatic homopolycyclic compound

Molecular Framework

Aliphatic homopolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	4.88	ALOGPS
logP	4.25	ChemAxon
logS	-4.8	ALOGPS
pKa (Strongest Acidic)	4.59	ChemAxon
pKa (Strongest Basic)	-3.2	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	5	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	97.99 Å²	ChemAxon
Rotatable Bond Count	2	ChemAxon
Refractivity	136.41 m³·mol⁻¹	ChemAxon
Polarizability	56.17 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

Not Available

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 2-{3,9,10-trihydroxy-3a,5a,5b,8,8,11a-hexamethyl-1h,2h,4h,5h,6h,7h,7ah,9h,10h,11h,11bh,12h,13bh-cyclopenta[a]chrysen-3-yl}propanoic acid (NP0186115)

MOL for NP0186115 (2-{3,9,10-trihydroxy-3a,5a,5b,8,8,11a-hexamethyl-1h,2h,4h,5h,6h,7h,7ah,9h,10h,11h,11bh,12h,13bh-cyclopenta[a]chrysen-3-yl}propanoic acid)

3D MOL for NP0186115 (2-{3,9,10-trihydroxy-3a,5a,5b,8,8,11a-hexamethyl-1h,2h,4h,5h,6h,7h,7ah,9h,10h,11h,11bh,12h,13bh-cyclopenta[a]chrysen-3-yl}propanoic acid)

3D SDF for NP0186115 (2-{3,9,10-trihydroxy-3a,5a,5b,8,8,11a-hexamethyl-1h,2h,4h,5h,6h,7h,7ah,9h,10h,11h,11bh,12h,13bh-cyclopenta[a]chrysen-3-yl}propanoic acid)

3D-SDF for NP0186115 (2-{3,9,10-trihydroxy-3a,5a,5b,8,8,11a-hexamethyl-1h,2h,4h,5h,6h,7h,7ah,9h,10h,11h,11bh,12h,13bh-cyclopenta[a]chrysen-3-yl}propanoic acid)

PDB for NP0186115 (2-{3,9,10-trihydroxy-3a,5a,5b,8,8,11a-hexamethyl-1h,2h,4h,5h,6h,7h,7ah,9h,10h,11h,11bh,12h,13bh-cyclopenta[a]chrysen-3-yl}propanoic acid)

3D PDB for NP0186115 (2-{3,9,10-trihydroxy-3a,5a,5b,8,8,11a-hexamethyl-1h,2h,4h,5h,6h,7h,7ah,9h,10h,11h,11bh,12h,13bh-cyclopenta[a]chrysen-3-yl}propanoic acid)

SMILES for NP0186115 (2-{3,9,10-trihydroxy-3a,5a,5b,8,8,11a-hexamethyl-1h,2h,4h,5h,6h,7h,7ah,9h,10h,11h,11bh,12h,13bh-cyclopenta[a]chrysen-3-yl}propanoic acid)

INCHI for NP0186115 (2-{3,9,10-trihydroxy-3a,5a,5b,8,8,11a-hexamethyl-1h,2h,4h,5h,6h,7h,7ah,9h,10h,11h,11bh,12h,13bh-cyclopenta[a]chrysen-3-yl}propanoic acid)

Structure for NP0186115 (2-{3,9,10-trihydroxy-3a,5a,5b,8,8,11a-hexamethyl-1h,2h,4h,5h,6h,7h,7ah,9h,10h,11h,11bh,12h,13bh-cyclopenta[a]chrysen-3-yl}propanoic acid)

3D Structure for NP0186115 (2-{3,9,10-trihydroxy-3a,5a,5b,8,8,11a-hexamethyl-1h,2h,4h,5h,6h,7h,7ah,9h,10h,11h,11bh,12h,13bh-cyclopenta[a]chrysen-3-yl}propanoic acid)