NP-MRD: Showing NP-Card for 2-{[(1-{[(3z,9z)-2,7-dihydroxy-5-isopropyl-1,6-diazacyclododeca-1,3,6,9-tetraen-8-yl]-c-hydroxycarbonimidoyl}-2-methylpropyl)-c-hydroxycarbonimidoyl]amino}-3-methylbutanoic acid (NP0185336)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-04 00:42:45 UTC

Updated at

2022-09-04 00:42:45 UTC

NP-MRD ID

NP0185336

Secondary Accession Numbers

None

Natural Product Identification

Common Name

2-{[(1-{[(3z,9z)-2,7-dihydroxy-5-isopropyl-1,6-diazacyclododeca-1,3,6,9-tetraen-8-yl]-c-hydroxycarbonimidoyl}-2-methylpropyl)-c-hydroxycarbonimidoyl]amino}-3-methylbutanoic acid

Description

2-[3-[1-(2,7-Dioxo-5-isopropyl-1,6-diaza-3,9-cyclododecadiene-8-ylcarbamoyl)-2-methylpropyl]ureido]isovaleric acid belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond. Based on a literature review very few articles have been published on 2-[3-[1-(2,7-Dioxo-5-isopropyl-1,6-diaza-3,9-cyclododecadiene-8-ylcarbamoyl)-2-methylpropyl]ureido]isovaleric acid.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309042202422D          

 35 35  0  0  0  0            999 V2000
    0.8250    3.2438    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395    2.8313    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2539    3.2438    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395    2.0063    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3364    1.7928    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9197    1.2094    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1332    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9582    0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.9197   -0.3844    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.3364   -0.9678    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395   -1.1813    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7426   -0.9678    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1592   -0.3844    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0543    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8793    0.4125    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2918   -0.3020    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8793   -1.0164    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1168   -0.3020    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5293   -1.0164    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3543   -1.0164    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7668   -0.3020    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7668   -1.7309    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3543   -2.4454    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7668   -3.1599    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3543   -3.8743    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5918   -3.1599    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5293   -2.4454    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1168   -3.1599    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1168   -1.7309    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5293    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3543    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1168    1.1270    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1592    1.2094    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5553    1.6219    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7426    1.7928    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  2  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  7  9  2  0  0  0  0
  9 10  1  4  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  2  0  0  0  0
 13 14  1  0  0  0  0
 15 14  1  4  0  0  0
 15 16  2  0  0  0  0
 16 17  1  0  0  0  0
 16 18  1  0  0  0  0
 19 18  1  4  0  0  0
 19 20  2  0  0  0  0
 20 21  1  0  0  0  0
 20 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  2  0  0  0  0
 24 26  1  0  0  0  0
 23 27  1  0  0  0  0
 27 28  1  0  0  0  0
 27 29  1  0  0  0  0
 18 30  1  0  0  0  0
 30 31  1  0  0  0  0
 30 32  1  0  0  0  0
 14 33  1  0  0  0  0
 33 34  1  0  0  0  0
 33 35  2  0  0  0  0
 35  4  1  4  0  0  0
M  END

     RDKit          3D

 74 74  0  0  0  0  0  0  0  0999 V2000
   -6.1348   -1.1562    1.8350 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7489   -1.1899    0.3889 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1285   -2.4586   -0.0790 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7924   -0.0175    0.0658 C   0  0  1  0  0  0  0  0  0  0  0  0
   -5.6382    1.1835    0.4104 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7776    2.1955   -0.4188 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1482    2.2851   -1.7352 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0863    2.5086   -2.7864 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9409    2.1717   -1.8462 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6765    2.0881   -2.2641 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7649    1.1159   -1.4559 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9389   -0.1834   -2.0304 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9549   -1.2509   -1.3035 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8085   -1.3019    0.1107 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.4005   -1.4433    0.4036 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.4451   -0.6627    0.8517 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2044    0.6343    1.2023 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8511   -1.1673    1.0303 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.8206   -0.3874    0.3287 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.7863    0.0165   -0.8741 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7422   -0.2512   -1.7488 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.8763    0.7873   -1.3598 N   0  0  0  0  0  0  0  0  0  0  0  0
    5.2216    0.5423   -0.8943 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.5733   -0.8555   -1.2114 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7581   -1.6219   -1.7984 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.8079   -1.4065   -0.8870 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.1957    1.5202   -1.5351 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7703    2.9128   -1.1532 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.5795    1.2737   -0.9780 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1484   -1.0535    2.5232 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5483   -1.5869    2.7347 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2013   -1.8688    3.3466 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5827   -0.5401    1.0508 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9389   -0.2668    2.2893 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7385   -0.0688    0.9755 N   0  0  0  0  0  0  0  0  0  0  0  0
   -7.2109   -0.8840    1.8966 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5432   -0.4611    2.4501 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0508   -2.1861    2.2511 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.6354   -0.9864   -0.2743 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9471   -3.2326   -0.1954 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4625   -2.8470    0.7092 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5906   -2.3514   -1.0223 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6108   -0.1025   -0.9944 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1277    1.1780    1.3832 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4348    3.0048   -0.0385 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4172    1.7477   -3.3635 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1734    3.1084   -2.1803 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4324    1.8124   -3.3181 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7244    1.4783   -1.7441 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8235    1.3004   -0.4104 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0618   -0.2512   -3.1356 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0939   -2.2122   -1.8470 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1530   -2.3993    0.3936 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.9127    1.2911    1.5062 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9536   -2.2196    0.6861 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4387    0.4027   -2.4406 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.7082    1.5270   -2.0495 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.2125    0.6644    0.2076 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.3175   -1.8528   -1.6420 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.1936    1.3820   -2.6298 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.1180    2.8683   -0.2769 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6850    3.5268   -0.9801 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.1858    3.3318   -1.9958 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.0875    2.2738   -0.8911 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.5140    0.8321    0.0297 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.1910    0.6403   -1.6668 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1383    0.0174    2.7836 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.8814   -2.1793    1.8749 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.5725   -2.2482    3.6345 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2479   -0.7504    2.9789 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7276   -2.6844    2.7703 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.7686   -2.3295    4.1969 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.3796   -1.2712    3.7881 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0708    0.5651    2.8103 H   0  0  0  0  0  0  0  0  0  0  0  0
 28 27  1  0
 27 29  1  0
 27 23  1  0
 23 22  1  0
 22 20  1  0
 20 21  1  0
 20 19  2  0
 19 18  1  0
 18 30  1  0
 30 31  1  0
 30 32  1  0
 18 16  1  0
 16 17  1  0
 16 15  2  0
 15 14  1  0
 14 13  1  0
 13 12  2  0
 12 11  1  0
 11 10  1  0
 10  9  1  0
  9  7  2  0
  7  8  1  0
  7  6  1  0
  6  5  2  0
  5  4  1  0
  4 35  1  0
 35 33  2  0
 33 34  1  0
  4  2  1  0
  2  1  1  0
  2  3  1  0
 23 24  1  0
 24 26  1  0
 24 25  2  0
 33 14  1  0
 28 61  1  0
 28 62  1  0
 28 63  1  0
 27 60  1  0
 29 64  1  0
 29 65  1  0
 29 66  1  0
 23 58  1  1
 22 57  1  0
 21 56  1  0
 18 55  1  6
 30 67  1  0
 31 68  1  0
 31 69  1  0
 31 70  1  0
 32 71  1  0
 32 72  1  0
 32 73  1  0
 17 54  1  0
 14 53  1  1
 13 52  1  0
 12 51  1  0
 11 49  1  0
 11 50  1  0
 10 47  1  0
 10 48  1  0
  8 46  1  0
  6 45  1  0
  5 44  1  0
  4 43  1  6
 34 74  1  0
  2 39  1  0
  1 36  1  0
  1 37  1  0
  1 38  1  0
  3 40  1  0
  3 41  1  0
  3 42  1  0
 26 59  1  0
M  END


  Mrv1652309042202422D          

 35 35  0  0  0  0            999 V2000
    0.8250    3.2438    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395    2.8313    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2539    3.2438    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395    2.0063    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3364    1.7928    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9197    1.2094    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1332    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9582    0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.9197   -0.3844    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.3364   -0.9678    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395   -1.1813    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7426   -0.9678    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1592   -0.3844    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0543    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8793    0.4125    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2918   -0.3020    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8793   -1.0164    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1168   -0.3020    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5293   -1.0164    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3543   -1.0164    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7668   -0.3020    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7668   -1.7309    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3543   -2.4454    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7668   -3.1599    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3543   -3.8743    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5918   -3.1599    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5293   -2.4454    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1168   -3.1599    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1168   -1.7309    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5293    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3543    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1168    1.1270    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1592    1.2094    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5553    1.6219    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7426    1.7928    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  2  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  7  9  2  0  0  0  0
  9 10  1  4  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  2  0  0  0  0
 13 14  1  0  0  0  0
 15 14  1  4  0  0  0
 15 16  2  0  0  0  0
 16 17  1  0  0  0  0
 16 18  1  0  0  0  0
 19 18  1  4  0  0  0
 19 20  2  0  0  0  0
 20 21  1  0  0  0  0
 20 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  2  0  0  0  0
 24 26  1  0  0  0  0
 23 27  1  0  0  0  0
 27 28  1  0  0  0  0
 27 29  1  0  0  0  0
 18 30  1  0  0  0  0
 30 31  1  0  0  0  0
 30 32  1  0  0  0  0
 14 33  1  0  0  0  0
 33 34  1  0  0  0  0
 33 35  2  0  0  0  0
 35  4  1  4  0  0  0
M  END
> <DATABASE_ID>
NP0185336

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(C)C(NC(O)=NC(C(C)C)C(O)=NC1\C=C/CCN=C(O)\C=C/C(N=C1O)C(C)C)C(O)=O

> <INCHI_IDENTIFIER>
InChI=1S/C24H39N5O6/c1-13(2)16-10-11-18(30)25-12-8-7-9-17(21(31)26-16)27-22(32)19(14(3)4)28-24(35)29-20(15(5)6)23(33)34/h7,9-11,13-17,19-20H,8,12H2,1-6H3,(H,25,30)(H,26,31)(H,27,32)(H,33,34)(H2,28,29,35)/b9-7-,11-10-

> <INCHI_KEY>
RUWSLQOIGKYPEZ-MNAJIYKBSA-N

> <FORMULA>
C24H39N5O6

> <MOLECULAR_WEIGHT>
493.605

> <EXACT_MASS>
493.290033996

> <JCHEM_ACCEPTOR_COUNT>
11

> <JCHEM_ATOM_COUNT>
74

> <JCHEM_AVERAGE_POLARIZABILITY>
52.22901459874713

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
6

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
2-{[(1-{[(3Z,9Z)-2,7-dihydroxy-5-(propan-2-yl)-1,6-diazacyclododeca-1,3,6,9-tetraen-8-yl]-C-hydroxycarbonimidoyl}-2-methylpropyl)-C-hydroxycarbonimidoyl]amino}-3-methylbutanoic acid

> <JCHEM_LOGP>
-1.5005137868077196

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
1

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA>
-0.2733999299103038

> <JCHEM_PKA_STRONGEST_ACIDIC>
-6.073833617203239

> <JCHEM_PKA_STRONGEST_BASIC>
15.361193793675492

> <JCHEM_POLAR_SURFACE_AREA>
179.69

> <JCHEM_REFRACTIVITY>
133.15490000000003

> <JCHEM_ROTATABLE_BOND_COUNT>
8

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
2-{[(1-{[(3Z,9Z)-2,7-dihydroxy-5-isopropyl-1,6-diazacyclododeca-1,3,6,9-tetraen-8-yl]-C-hydroxycarbonimidoyl}-2-methylpropyl)-C-hydroxycarbonimidoyl]amino}-3-methylbutanoic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 04-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   04-SEP-22         0                                  
HETATM    1  C   UNK     0       1.540   6.055   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       2.874   5.285   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       4.207   6.055   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       2.874   3.745   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       4.361   3.346   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       5.450   2.258   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       5.849   0.770   0.000  0.00  0.00           C+0
HETATM    8  O   UNK     0       7.389   0.770   0.000  0.00  0.00           O+0
HETATM    9  N   UNK     0       5.450  -0.718   0.000  0.00  0.00           N+0
HETATM   10  C   UNK     0       4.361  -1.806   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       2.874  -2.205   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       1.386  -1.806   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       0.297  -0.718   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0      -0.101   0.770   0.000  0.00  0.00           C+0
HETATM   15  N   UNK     0      -1.641   0.770   0.000  0.00  0.00           N+0
HETATM   16  C   UNK     0      -2.411  -0.564   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0      -1.641  -1.897   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0      -3.951  -0.564   0.000  0.00  0.00           C+0
HETATM   19  N   UNK     0      -4.721  -1.897   0.000  0.00  0.00           N+0
HETATM   20  C   UNK     0      -6.261  -1.897   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0      -7.031  -0.564   0.000  0.00  0.00           O+0
HETATM   22  N   UNK     0      -7.031  -3.231   0.000  0.00  0.00           N+0
HETATM   23  C   UNK     0      -6.261  -4.565   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      -7.031  -5.898   0.000  0.00  0.00           C+0
HETATM   25  O   UNK     0      -6.261  -7.232   0.000  0.00  0.00           O+0
HETATM   26  O   UNK     0      -8.571  -5.898   0.000  0.00  0.00           O+0
HETATM   27  C   UNK     0      -4.721  -4.565   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0      -3.951  -5.898   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0      -3.951  -3.231   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0      -4.721   0.770   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0      -6.261   0.770   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0      -3.951   2.104   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0       0.297   2.258   0.000  0.00  0.00           C+0
HETATM   34  O   UNK     0      -1.036   3.028   0.000  0.00  0.00           O+0
HETATM   35  N   UNK     0       1.386   3.346   0.000  0.00  0.00           N+0
CONECT    1    2                                                            
CONECT    2    1    3    4                                                  
CONECT    3    2                                                            
CONECT    4    2    5   35                                                  
CONECT    5    4    6                                                       
CONECT    6    5    7                                                       
CONECT    7    6    8    9                                                  
CONECT    8    7                                                            
CONECT    9    7   10                                                       
CONECT   10    9   11                                                       
CONECT   11   10   12                                                       
CONECT   12   11   13                                                       
CONECT   13   12   14                                                       
CONECT   14   13   15   33                                                  
CONECT   15   14   16                                                       
CONECT   16   15   17   18                                                  
CONECT   17   16                                                            
CONECT   18   16   19   30                                                  
CONECT   19   18   20                                                       
CONECT   20   19   21   22                                                  
CONECT   21   20                                                            
CONECT   22   20   23                                                       
CONECT   23   22   24   27                                                  
CONECT   24   23   25   26                                                  
CONECT   25   24                                                            
CONECT   26   24                                                            
CONECT   27   23   28   29                                                  
CONECT   28   27                                                            
CONECT   29   27                                                            
CONECT   30   18   31   32                                                  
CONECT   31   30                                                            
CONECT   32   30                                                            
CONECT   33   14   34   35                                                  
CONECT   34   33                                                            
CONECT   35   33    4                                                       
MASTER        0    0    0    0    0    0    0    0   35    0   70    0
END

View in JSmol

Synonyms

Value	Source
2-[3-[1-(2,7-Dioxo-5-isopropyl-1,6-diaza-3,9-cyclododecadiene-8-ylcarbamoyl)-2-methylpropyl]ureido]isovalerate	Generator

Chemical Formula

C₂₄H₃₉N₅O₆

Average Mass

493.6050 Da

Monoisotopic Mass

493.29003 Da

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

Not Available

SMILES

CC(C)C(NC(O)=NC(C(C)C)C(O)=NC1\C=C/CCN=C(O)\C=C/C(N=C1O)C(C)C)C(O)=O

InChI Identifier

InChI=1S/C24H39N5O6/c1-13(2)16-10-11-18(30)25-12-8-7-9-17(21(31)26-16)27-22(32)19(14(3)4)28-24(35)29-20(15(5)6)23(33)34/h7,9-11,13-17,19-20H,8,12H2,1-6H3,(H,25,30)(H,26,31)(H,27,32)(H,33,34)(H2,28,29,35)/b9-7-,11-10-

InChI Key

RUWSLQOIGKYPEZ-MNAJIYKBSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Not Available

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Carboxylic acids and derivatives

Sub Class

Amino acids, peptides, and analogues

Direct Parent

Dipeptides

Alternative Parents

Substituents

Alpha-dipeptide
Valine or derivatives
N-carbamoyl-alpha-amino acid or derivatives
N-carbamoyl-alpha-amino acid
N-acyl-alpha amino acid or derivatives
Macrolactam
Alpha-amino acid amide
Alpha-amino acid or derivatives
N-substituted-alpha-amino acid
Methyl-branched fatty acid
Heterocyclic fatty acid
Branched fatty acid
Fatty acyl
N-acyl-amine
Fatty amide
Urea
Secondary carboxylic acid amide
Carbonic acid derivative
Lactam
Carboxamide group
Azacycle
Organoheterocyclic compound
Monocarboxylic acid or derivatives
Carboxylic acid
Organic nitrogen compound
Organic oxygen compound
Organopnictogen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Organonitrogen compound
Carbonyl group
Aliphatic heteromonocyclic compound

Molecular Framework

Aliphatic heteromonocyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

78444161

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

102012801

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 2-{[(1-{[(3z,9z)-2,7-dihydroxy-5-isopropyl-1,6-diazacyclododeca-1,3,6,9-tetraen-8-yl]-c-hydroxycarbonimidoyl}-2-methylpropyl)-c-hydroxycarbonimidoyl]amino}-3-methylbutanoic acid (NP0185336)

MOL for NP0185336 (2-{[(1-{[(3z,9z)-2,7-dihydroxy-5-isopropyl-1,6-diazacyclododeca-1,3,6,9-tetraen-8-yl]-c-hydroxycarbonimidoyl}-2-methylpropyl)-c-hydroxycarbonimidoyl]amino}-3-methylbutanoic acid)

3D MOL for NP0185336 (2-{[(1-{[(3z,9z)-2,7-dihydroxy-5-isopropyl-1,6-diazacyclododeca-1,3,6,9-tetraen-8-yl]-c-hydroxycarbonimidoyl}-2-methylpropyl)-c-hydroxycarbonimidoyl]amino}-3-methylbutanoic acid)

3D SDF for NP0185336 (2-{[(1-{[(3z,9z)-2,7-dihydroxy-5-isopropyl-1,6-diazacyclododeca-1,3,6,9-tetraen-8-yl]-c-hydroxycarbonimidoyl}-2-methylpropyl)-c-hydroxycarbonimidoyl]amino}-3-methylbutanoic acid)

3D-SDF for NP0185336 (2-{[(1-{[(3z,9z)-2,7-dihydroxy-5-isopropyl-1,6-diazacyclododeca-1,3,6,9-tetraen-8-yl]-c-hydroxycarbonimidoyl}-2-methylpropyl)-c-hydroxycarbonimidoyl]amino}-3-methylbutanoic acid)

PDB for NP0185336 (2-{[(1-{[(3z,9z)-2,7-dihydroxy-5-isopropyl-1,6-diazacyclododeca-1,3,6,9-tetraen-8-yl]-c-hydroxycarbonimidoyl}-2-methylpropyl)-c-hydroxycarbonimidoyl]amino}-3-methylbutanoic acid)

3D PDB for NP0185336 (2-{[(1-{[(3z,9z)-2,7-dihydroxy-5-isopropyl-1,6-diazacyclododeca-1,3,6,9-tetraen-8-yl]-c-hydroxycarbonimidoyl}-2-methylpropyl)-c-hydroxycarbonimidoyl]amino}-3-methylbutanoic acid)

SMILES for NP0185336 (2-{[(1-{[(3z,9z)-2,7-dihydroxy-5-isopropyl-1,6-diazacyclododeca-1,3,6,9-tetraen-8-yl]-c-hydroxycarbonimidoyl}-2-methylpropyl)-c-hydroxycarbonimidoyl]amino}-3-methylbutanoic acid)

INCHI for NP0185336 (2-{[(1-{[(3z,9z)-2,7-dihydroxy-5-isopropyl-1,6-diazacyclododeca-1,3,6,9-tetraen-8-yl]-c-hydroxycarbonimidoyl}-2-methylpropyl)-c-hydroxycarbonimidoyl]amino}-3-methylbutanoic acid)

Structure for NP0185336 (2-{[(1-{[(3z,9z)-2,7-dihydroxy-5-isopropyl-1,6-diazacyclododeca-1,3,6,9-tetraen-8-yl]-c-hydroxycarbonimidoyl}-2-methylpropyl)-c-hydroxycarbonimidoyl]amino}-3-methylbutanoic acid)

3D Structure for NP0185336 (2-{[(1-{[(3z,9z)-2,7-dihydroxy-5-isopropyl-1,6-diazacyclododeca-1,3,6,9-tetraen-8-yl]-c-hydroxycarbonimidoyl}-2-methylpropyl)-c-hydroxycarbonimidoyl]amino}-3-methylbutanoic acid)