NP-MRD: Showing NP-Card for 1-(2h-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one (NP0180968)

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Record Information

Version

2.0

Created at

2022-09-03 19:24:21 UTC

Updated at

2022-09-03 19:24:22 UTC

NP-MRD ID

NP0180968

Secondary Accession Numbers

None

Natural Product Identification

Common Name

1-(2h-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one

Description

1-(2H-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one belongs to the class of organic compounds known as stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 ) are derived from the common phenylpropene (C6-C3) skeleton building block. The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. 1-(2h-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one is found in Ocotea porosa. 1-(2H-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004191513322D          

 25 27  0  0  0  0            999 V2000
    7.6391    3.5854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.9246    3.1729    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.2102    3.5854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4957    3.1729    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7812    3.5854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7812    4.4104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4957    4.8229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4957    5.6479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2102    6.0604    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2102    6.8854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2102    4.4104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.9246    4.8229    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.0668    3.1729    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523    3.5854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0668    2.3479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7812    1.9354    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523    1.9354    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523    1.1104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378    0.6979    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9233    1.1104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1387    0.8555    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.6538    1.5229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1387    2.1904    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9233    1.9354    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378    2.3479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
  7 11  2  0  0  0  0
  3 11  1  0  0  0  0
 11 12  1  0  0  0  0
  5 13  1  0  0  0  0
 13 14  1  0  0  0  0
 13 15  1  0  0  0  0
 15 16  2  0  0  0  0
 15 17  1  0  0  0  0
 17 18  2  0  0  0  0
 18 19  1  0  0  0  0
 19 20  2  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 20 24  1  0  0  0  0
 24 25  2  0  0  0  0
 17 25  1  0  0  0  0
M  END

     RDKit          3D

 45 47  0  0  0  0  0  0  0  0999 V2000
   -5.9526    2.6890   -1.1385 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6530    2.6387   -0.9266 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7444    1.7855   -1.7335 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9976    0.8173   -0.8914 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6783    1.0804   -0.5446 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9116    0.2519    0.2436 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5121    0.5935    0.5782 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.6646    0.6564    2.0790 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4249   -0.3829   -0.0191 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9506   -1.3670   -0.6475 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8620   -0.2588    0.0851 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4670    0.7910    0.7399 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8516    0.8410    0.7988 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6730   -0.1016    0.2386 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0741   -1.1555   -0.4187 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7021   -1.2212   -0.4869 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.1034   -1.9833   -0.9042 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.2247   -1.1126   -1.0376 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0466   -0.3093    0.1396 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4804   -0.9100    0.7208 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7849   -1.2093    0.4008 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4279   -2.3476    0.8360 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8132   -3.3226    1.6550 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5355   -0.3474   -0.4016 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.8546   -0.6605   -0.7215 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.5744    3.3247   -0.5258 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4394    2.0949   -1.9327 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2385    3.2471   -0.1306 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0442    2.4091   -2.3460 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3864    1.2389   -2.4783 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2589    2.0093   -0.9395 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7305    1.5920    0.1717 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2501    0.2116    2.5412 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.8339    1.6902    2.4174 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5125    0.0261    2.3872 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.8833    1.5756    1.2038 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3101    1.6710    1.3169 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2232   -2.0352   -0.9950 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.1753   -1.6473   -1.0411 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.0769   -0.4183   -1.8897 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9107   -1.6022    1.3529 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7641   -3.4513    1.3033 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7974   -3.0032    2.7337 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3653   -4.2838    1.6399 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.4393   -0.1043   -1.2909 H   0  0  0  0  0  0  0  0  0  0  0  0
 23 22  1  0
 22 21  1  0
 21 20  2  0
 20  6  1  0
  6  5  2  0
  5  4  1  0
  4  3  1  0
  3  2  1  0
  2  1  2  3
  4 24  2  0
 24 25  1  0
  6  7  1  0
  7  8  1  0
  7  9  1  0
  9 10  2  0
  9 11  1  0
 11 12  2  0
 12 13  1  0
 13 14  2  0
 14 19  1  0
 19 18  1  0
 18 17  1  0
 17 15  1  0
 15 16  2  0
 24 21  1  0
 16 11  1  0
 15 14  1  0
 23 42  1  0
 23 43  1  0
 23 44  1  0
 20 41  1  0
  5 31  1  0
  3 29  1  0
  3 30  1  0
  2 28  1  0
  1 26  1  0
  1 27  1  0
 25 45  1  0
  7 32  1  6
  8 33  1  0
  8 34  1  0
  8 35  1  0
 12 36  1  0
 13 37  1  0
 18 39  1  0
 18 40  1  0
 16 38  1  0
M  END


  Mrv1533004191513322D          

 25 27  0  0  0  0            999 V2000
    7.6391    3.5854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.9246    3.1729    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.2102    3.5854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4957    3.1729    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7812    3.5854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7812    4.4104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4957    4.8229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4957    5.6479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2102    6.0604    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2102    6.8854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2102    4.4104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.9246    4.8229    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.0668    3.1729    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523    3.5854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0668    2.3479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7812    1.9354    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523    1.9354    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523    1.1104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378    0.6979    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9233    1.1104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1387    0.8555    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.6538    1.5229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1387    2.1904    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9233    1.9354    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378    2.3479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
  7 11  2  0  0  0  0
  3 11  1  0  0  0  0
 11 12  1  0  0  0  0
  5 13  1  0  0  0  0
 13 14  1  0  0  0  0
 13 15  1  0  0  0  0
 15 16  2  0  0  0  0
 15 17  1  0  0  0  0
 17 18  2  0  0  0  0
 18 19  1  0  0  0  0
 19 20  2  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 20 24  1  0  0  0  0
 24 25  2  0  0  0  0
 17 25  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0180968

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC1=CC(=CC(CC=C)=C1O)C(C)C(=O)C1=CC=C2OCOC2=C1

> <INCHI_IDENTIFIER>
InChI=1S/C20H20O5/c1-4-5-13-8-15(10-18(23-3)20(13)22)12(2)19(21)14-6-7-16-17(9-14)25-11-24-16/h4,6-10,12,22H,1,5,11H2,2-3H3

> <INCHI_KEY>
KMKJYXJQJSQMJU-UHFFFAOYSA-N

> <FORMULA>
C20H20O5

> <MOLECULAR_WEIGHT>
340.375

> <EXACT_MASS>
340.131073744

> <JCHEM_ACCEPTOR_COUNT>
5

> <JCHEM_ATOM_COUNT>
45

> <JCHEM_AVERAGE_POLARIZABILITY>
35.92880486731798

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
1-(2H-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one

> <ALOGPS_LOGP>
4.00

> <JCHEM_LOGP>
4.168787045999999

> <ALOGPS_LOGS>
-4.52

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
3

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
17.850596338023113

> <JCHEM_PKA_STRONGEST_ACIDIC>
9.745693765972888

> <JCHEM_PKA_STRONGEST_BASIC>
-4.515728500106891

> <JCHEM_POLAR_SURFACE_AREA>
64.99000000000001

> <JCHEM_REFRACTIVITY>
94.25550000000001

> <JCHEM_ROTATABLE_BOND_COUNT>
6

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
1.04e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
1-(2H-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 19-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   19-APR-15         0                                  
HETATM    1  C   UNK     0      14.260   6.693   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0      12.926   5.923   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0      11.592   6.693   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      10.259   5.923   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       8.925   6.693   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       8.925   8.233   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      10.259   9.003   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      10.259  10.543   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      11.592  11.313   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      11.592  12.853   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0      11.592   8.233   0.000  0.00  0.00           C+0
HETATM   12  O   UNK     0      12.926   9.003   0.000  0.00  0.00           O+0
HETATM   13  C   UNK     0       7.591   5.923   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       6.258   6.693   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       7.591   4.383   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0       8.925   3.613   0.000  0.00  0.00           O+0
HETATM   17  C   UNK     0       6.258   3.613   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       6.258   2.073   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       4.924   1.303   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       3.590   2.073   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0       2.126   1.597   0.000  0.00  0.00           O+0
HETATM   22  C   UNK     0       1.220   2.843   0.000  0.00  0.00           C+0
HETATM   23  O   UNK     0       2.126   4.089   0.000  0.00  0.00           O+0
HETATM   24  C   UNK     0       3.590   3.613   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       4.924   4.383   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4   11                                                  
CONECT    4    3    5                                                       
CONECT    5    4    6   13                                                  
CONECT    6    5    7                                                       
CONECT    7    6    8   11                                                  
CONECT    8    7    9                                                       
CONECT    9    8   10                                                       
CONECT   10    9                                                            
CONECT   11    7    3   12                                                  
CONECT   12   11                                                            
CONECT   13    5   14   15                                                  
CONECT   14   13                                                            
CONECT   15   13   16   17                                                  
CONECT   16   15                                                            
CONECT   17   15   18   25                                                  
CONECT   18   17   19                                                       
CONECT   19   18   20                                                       
CONECT   20   19   21   24                                                  
CONECT   21   20   22                                                       
CONECT   22   21   23                                                       
CONECT   23   22   24                                                       
CONECT   24   23   20   25                                                  
CONECT   25   24   17                                                       
MASTER        0    0    0    0    0    0    0    0   25    0   54    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₀H₂₀O₅

Average Mass

340.3750 Da

Monoisotopic Mass

340.13107 Da

IUPAC Name

1-(2H-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one

Traditional Name

1-(2H-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one

CAS Registry Number

Not Available

SMILES

COC1=CC(=CC(CC=C)=C1O)C(C)C(=O)C1=CC=C2OCOC2=C1

InChI Identifier

InChI=1S/C20H20O5/c1-4-5-13-8-15(10-18(23-3)20(13)22)12(2)19(21)14-6-7-16-17(9-14)25-11-24-16/h4,6-10,12,22H,1,5,11H2,2-3H3

InChI Key

KMKJYXJQJSQMJU-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Ocotea porosa	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 ) are derived from the common phenylpropene (C6-C3) skeleton building block. The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids.

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Stilbenes

Sub Class

Not Available

Direct Parent

Stilbenes

Alternative Parents

Substituents

Stilbene
Methoxyphenol
Benzodioxole
Phenoxy compound
Anisole
Phenol ether
Methoxybenzene
Aryl alkyl ketone
Aryl ketone
Alkyl aryl ether
Phenol
Monocyclic benzene moiety
Benzenoid
Ketone
Acetal
Oxacycle
Ether
Organoheterocyclic compound
Organooxygen compound
Hydrocarbon derivative
Organic oxide
Organic oxygen compound
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	4	ALOGPS
logP	4.17	ChemAxon
logS	-4.5	ALOGPS
pKa (Strongest Acidic)	9.75	ChemAxon
pKa (Strongest Basic)	-4.5	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	5	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	64.99 Å²	ChemAxon
Rotatable Bond Count	6	ChemAxon
Refractivity	94.26 m³·mol⁻¹	ChemAxon
Polarizability	35.93 Å³	ChemAxon
Number of Rings	3	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

14132424

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 1-(2h-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one (NP0180968)

MOL for NP0180968 (1-(2h-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one)

3D MOL for NP0180968 (1-(2h-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one)

3D SDF for NP0180968 (1-(2h-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one)

3D-SDF for NP0180968 (1-(2h-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one)

PDB for NP0180968 (1-(2h-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one)

3D PDB for NP0180968 (1-(2h-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one)

SMILES for NP0180968 (1-(2h-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one)

INCHI for NP0180968 (1-(2h-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one)

Structure for NP0180968 (1-(2h-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one)

3D Structure for NP0180968 (1-(2h-1,3-benzodioxol-5-yl)-2-[4-hydroxy-3-methoxy-5-(prop-2-en-1-yl)phenyl]propan-1-one)