NP-MRD: Showing NP-Card for [(2r,3s,4s,5r,6s)-6-[(3s,3'r,3ar,6s,6ar)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-dihydro-5h-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate (NP0168436)

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Record Information

Version

2.0

Created at

2022-09-03 04:15:01 UTC

Updated at

2022-09-03 04:15:01 UTC

NP-MRD ID

NP0168436

Secondary Accession Numbers

None

Natural Product Identification

Common Name

[(2r,3s,4s,5r,6s)-6-[(3s,3'r,3ar,6s,6ar)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-dihydro-5h-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate

Description

[(2R,3S,4S,5R,6S)-6-[(3S,3'R,3aR,6S,6aR)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-tetrahydro-2H-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate belongs to the class of organic compounds known as hexacarboxylic acids and derivatives. These are carboxylic acids containing exactly six carboxyl groups. Based on a literature review very few articles have been published on [(2R,3S,4S,5R,6S)-6-[(3S,3'R,3aR,6S,6aR)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-tetrahydro-2H-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309032206152D          

 46 50  0  0  1  0            999 V2000
   -0.4693   -3.0187    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1340   -2.4560    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
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   -0.0516   -1.6522    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5904   -1.0535    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9548   -0.1521    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
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    1.9846    0.8385    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.8774    1.0413    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.3319    0.3624    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.6491    1.0388    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.5649    0.8741    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
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    5.3591   -0.4432    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.2070   -0.2603    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.7530    0.3939    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.9167   -0.7693    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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    2.5699    0.0462    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.8080   -0.2700    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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  1  2  1  0  0  0  0
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  8 35  1  0  0  0  0
 35 36  1  1  0  0  0
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  6 42  1  0  0  0  0
 42 43  1  1  0  0  0
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 44 45  1  0  0  0  0
 44 46  2  0  0  0  0
M  END

     RDKit          3D

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M  END


  Mrv1652309032206152D          

 46 50  0  0  1  0            999 V2000
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    6.9167   -0.7693    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.8681   -0.2645    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.4376   -0.9683    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6352   -0.7762    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6352   -1.6841    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.5699    0.0462    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.8080   -0.2700    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.2717    0.3570    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3993   -0.1518    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7023    1.0607    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5047    0.8686    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.1316    1.4048    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9808    2.2159    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6077    2.7521    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3856    2.4773    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0031    3.0800    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.5365    1.6662    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9095    1.1300    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4127    1.4331    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.3114    2.4266    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.6307    2.9943    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1297    2.5821    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5565    3.8712    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.6118    1.2350    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.1138    1.8095    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3829    0.4424    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.5621    0.4030    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3141    0.8021    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3435    1.6266    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0135    0.3644    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  2  4  1  0  0  0  0
  4  5  1  0  0  0  0
  6  5  1  6  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  6  0  0  0
 10  9  1  6  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  6  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 15 17  2  0  0  0  0
 13 18  1  0  0  0  0
 10 18  1  0  0  0  0
 18 19  1  1  0  0  0
 19 20  1  0  0  0  0
 20 21  2  0  0  0  0
 20 22  1  0  0  0  0
 10 22  1  0  0  0  0
 22 23  1  1  0  0  0
 23 24  1  0  0  0  0
 24 25  2  0  0  0  0
 24 26  1  0  0  0  0
 26 27  1  0  0  0  0
 22 27  1  0  0  0  0
 27 28  1  6  0  0  0
 28 29  2  0  0  0  0
 29 30  1  0  0  0  0
 30 31  2  0  0  0  0
 31 32  1  0  0  0  0
 31 33  1  0  0  0  0
 33 34  2  0  0  0  0
 28 34  1  0  0  0  0
  8 35  1  0  0  0  0
 35 36  1  1  0  0  0
 36 37  1  0  0  0  0
 37 38  1  0  0  0  0
 37 39  2  0  0  0  0
 35 40  1  0  0  0  0
 40 41  1  6  0  0  0
 40 42  1  0  0  0  0
  6 42  1  0  0  0  0
 42 43  1  1  0  0  0
 43 44  1  0  0  0  0
 44 45  1  0  0  0  0
 44 46  2  0  0  0  0
M  END
> <DATABASE_ID>
NP0168436

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(=O)OC[C@H]1O[C@@H](O[C@]23OC[C@H](OC(C)=O)[C@H]2OC(=O)[C@@]32OC(=O)C[C@@H]2C2=CC=C(O)C=C2)[C@H](OC(C)=O)[C@@H](O)[C@@H]1OC(C)=O

> <INCHI_IDENTIFIER>
InChI=1S/C29H32O17/c1-12(30)38-10-19-23(41-14(3)32)22(36)24(42-15(4)33)26(43-19)46-29-25(20(11-39-29)40-13(2)31)44-27(37)28(29)18(9-21(35)45-28)16-5-7-17(34)8-6-16/h5-8,18-20,22-26,34,36H,9-11H2,1-4H3/t18-,19-,20+,22+,23-,24-,25-,26+,28-,29-/m1/s1

> <INCHI_KEY>
IFUGOZKKYGPOOE-XJHLMOCLSA-N

> <FORMULA>
C29H32O17

> <MOLECULAR_WEIGHT>
652.558

> <EXACT_MASS>
652.16394957

> <JCHEM_ACCEPTOR_COUNT>
11

> <JCHEM_ATOM_COUNT>
78

> <JCHEM_AVERAGE_POLARIZABILITY>
60.897887573146626

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
2

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
[(2R,3S,4S,5R,6S)-6-[(3S,3'R,3aR,6S,6aR)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-tetrahydro-2H-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate

> <ALOGPS_LOGP>
0.90

> <JCHEM_LOGP>
0.15971012333333323

> <ALOGPS_LOGS>
-2.86

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
12.920762126303593

> <JCHEM_PKA_STRONGEST_ACIDIC>
9.498491199884933

> <JCHEM_PKA_STRONGEST_BASIC>
-3.708330531021571

> <JCHEM_POLAR_SURFACE_AREA>
225.95

> <JCHEM_REFRACTIVITY>
140.31430000000003

> <JCHEM_ROTATABLE_BOND_COUNT>
12

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
9.09e-01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
[(2R,3S,4S,5R,6S)-6-[(3S,3'R,3aR,6S,6aR)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-dihydro-5H-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 03-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   03-SEP-22         0                                  
HETATM    1  C   UNK     0      -0.876  -5.635   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       0.250  -4.585   0.000  0.00  0.00           C+0
HETATM    3  O   UNK     0       1.723  -5.035   0.000  0.00  0.00           O+0
HETATM    4  O   UNK     0      -0.096  -3.084   0.000  0.00  0.00           O+0
HETATM    5  C   UNK     0       1.102  -1.966   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       1.782  -0.284   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0       3.277   0.086   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0       3.705   1.565   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0       5.371   1.944   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0       6.220   0.677   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0       6.812   1.939   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0       8.521   1.632   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       8.643   0.096   0.000  0.00  0.00           C+0
HETATM   14  O   UNK     0      10.004  -0.827   0.000  0.00  0.00           O+0
HETATM   15  C   UNK     0      11.586  -0.486   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0      12.606   0.735   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0      12.911  -1.436   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0       7.221  -0.494   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0       6.417  -1.807   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0       4.919  -1.449   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0       4.919  -3.144   0.000  0.00  0.00           O+0
HETATM   22  C   UNK     0       4.797   0.086   0.000  0.00  0.00           C+0
HETATM   23  O   UNK     0       3.375  -0.504   0.000  0.00  0.00           O+0
HETATM   24  C   UNK     0       2.374   0.666   0.000  0.00  0.00           C+0
HETATM   25  O   UNK     0       0.745  -0.283   0.000  0.00  0.00           O+0
HETATM   26  C   UNK     0       3.178   1.980   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       4.675   1.621   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       5.846   2.622   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       5.564   4.136   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       6.734   5.137   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       8.186   4.624   0.000  0.00  0.00           C+0
HETATM   32  O   UNK     0       9.339   5.749   0.000  0.00  0.00           O+0
HETATM   33  C   UNK     0       8.468   3.110   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0       7.298   2.109   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       2.637   2.675   0.000  0.00  0.00           C+0
HETATM   36  O   UNK     0       2.448   4.530   0.000  0.00  0.00           O+0
HETATM   37  C   UNK     0       1.177   5.589   0.000  0.00  0.00           C+0
HETATM   38  C   UNK     0      -0.242   4.820   0.000  0.00  0.00           C+0
HETATM   39  O   UNK     0       1.039   7.226   0.000  0.00  0.00           O+0
HETATM   40  C   UNK     0       1.142   2.305   0.000  0.00  0.00           C+0
HETATM   41  O   UNK     0      -0.212   3.378   0.000  0.00  0.00           O+0
HETATM   42  C   UNK     0       0.715   0.826   0.000  0.00  0.00           C+0
HETATM   43  O   UNK     0      -1.049   0.752   0.000  0.00  0.00           O+0
HETATM   44  C   UNK     0      -2.453   1.497   0.000  0.00  0.00           C+0
HETATM   45  C   UNK     0      -2.508   3.036   0.000  0.00  0.00           C+0
HETATM   46  O   UNK     0      -3.758   0.680   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3    4                                                  
CONECT    3    2                                                            
CONECT    4    2    5                                                       
CONECT    5    4    6                                                       
CONECT    6    5    7   42                                                  
CONECT    7    6    8                                                       
CONECT    8    7    9   35                                                  
CONECT    9    8   10                                                       
CONECT   10    9   11   18   22                                             
CONECT   11   10   12                                                       
CONECT   12   11   13                                                       
CONECT   13   12   14   18                                                  
CONECT   14   13   15                                                       
CONECT   15   14   16   17                                                  
CONECT   16   15                                                            
CONECT   17   15                                                            
CONECT   18   13   10   19                                                  
CONECT   19   18   20                                                       
CONECT   20   19   21   22                                                  
CONECT   21   20                                                            
CONECT   22   20   10   23   27                                             
CONECT   23   22   24                                                       
CONECT   24   23   25   26                                                  
CONECT   25   24                                                            
CONECT   26   24   27                                                       
CONECT   27   26   22   28                                                  
CONECT   28   27   29   34                                                  
CONECT   29   28   30                                                       
CONECT   30   29   31                                                       
CONECT   31   30   32   33                                                  
CONECT   32   31                                                            
CONECT   33   31   34                                                       
CONECT   34   33   28                                                       
CONECT   35    8   36   40                                                  
CONECT   36   35   37                                                       
CONECT   37   36   38   39                                                  
CONECT   38   37                                                            
CONECT   39   37                                                            
CONECT   40   35   41   42                                                  
CONECT   41   40                                                            
CONECT   42   40    6   43                                                  
CONECT   43   42   44                                                       
CONECT   44   43   45   46                                                  
CONECT   45   44                                                            
CONECT   46   44                                                            
MASTER        0    0    0    0    0    0    0    0   46    0  100    0
END

View in JSmol

Synonyms

Value	Source
[(2R,3S,4S,5R,6S)-6-[(3S,3'r,3AR,6S,6ar)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-tetrahydro-2H-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetic acid	Generator

Chemical Formula

C₂₉H₃₂O₁₇

Average Mass

652.5580 Da

Monoisotopic Mass

652.16395 Da

IUPAC Name

[(2R,3S,4S,5R,6S)-6-[(3S,3'R,3aR,6S,6aR)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-tetrahydro-2H-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate

Traditional Name

[(2R,3S,4S,5R,6S)-6-[(3S,3'R,3aR,6S,6aR)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-dihydro-5H-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate

CAS Registry Number

Not Available

SMILES

CC(=O)OC[C@H]1O[C@@H](O[C@]23OC[C@H](OC(C)=O)[C@H]2OC(=O)[C@@]32OC(=O)C[C@@H]2C2=CC=C(O)C=C2)[C@H](OC(C)=O)[C@@H](O)[C@@H]1OC(C)=O

InChI Identifier

InChI=1S/C29H32O17/c1-12(30)38-10-19-23(41-14(3)32)22(36)24(42-15(4)33)26(43-19)46-29-25(20(11-39-29)40-13(2)31)44-27(37)28(29)18(9-21(35)45-28)16-5-7-17(34)8-6-16/h5-8,18-20,22-26,34,36H,9-11H2,1-4H3/t18-,19-,20+,22+,23-,24-,25-,26+,28-,29-/m1/s1

InChI Key

IFUGOZKKYGPOOE-XJHLMOCLSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Not Available

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as hexacarboxylic acids and derivatives. These are carboxylic acids containing exactly six carboxyl groups.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Carboxylic acids and derivatives

Sub Class

Hexacarboxylic acids and derivatives

Direct Parent

Hexacarboxylic acids and derivatives

Alternative Parents

Substituents

Hexacarboxylic acid or derivatives
Disaccharide
Glycosyl compound
O-glycosyl compound
Isosorbide
Furofuran
Ketal
1-hydroxy-2-unsubstituted benzenoid
Phenol
Oxane
Benzenoid
Monocyclic benzene moiety
Gamma butyrolactone
Tetrahydrofuran
Secondary alcohol
Lactone
Carboxylic acid ester
Organoheterocyclic compound
Oxacycle
Acetal
Organic oxide
Hydrocarbon derivative
Alcohol
Carbonyl group
Organic oxygen compound
Organooxygen compound
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	0.9	ALOGPS
logP	0.16	ChemAxon
logS	-2.9	ALOGPS
pKa (Strongest Acidic)	9.5	ChemAxon
pKa (Strongest Basic)	-3.7	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	11	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	225.95 Å²	ChemAxon
Rotatable Bond Count	12	ChemAxon
Refractivity	140.31 m³·mol⁻¹	ChemAxon
Polarizability	60.9 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

162898754

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for [(2r,3s,4s,5r,6s)-6-[(3s,3'r,3ar,6s,6ar)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-dihydro-5h-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate (NP0168436)

MOL for NP0168436 ([(2r,3s,4s,5r,6s)-6-[(3s,3'r,3ar,6s,6ar)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-dihydro-5h-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate)

3D MOL for NP0168436 ([(2r,3s,4s,5r,6s)-6-[(3s,3'r,3ar,6s,6ar)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-dihydro-5h-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate)

3D SDF for NP0168436 ([(2r,3s,4s,5r,6s)-6-[(3s,3'r,3ar,6s,6ar)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-dihydro-5h-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate)

3D-SDF for NP0168436 ([(2r,3s,4s,5r,6s)-6-[(3s,3'r,3ar,6s,6ar)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-dihydro-5h-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate)

PDB for NP0168436 ([(2r,3s,4s,5r,6s)-6-[(3s,3'r,3ar,6s,6ar)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-dihydro-5h-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate)

3D PDB for NP0168436 ([(2r,3s,4s,5r,6s)-6-[(3s,3'r,3ar,6s,6ar)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-dihydro-5h-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate)

SMILES for NP0168436 ([(2r,3s,4s,5r,6s)-6-[(3s,3'r,3ar,6s,6ar)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-dihydro-5h-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate)

INCHI for NP0168436 ([(2r,3s,4s,5r,6s)-6-[(3s,3'r,3ar,6s,6ar)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-dihydro-5h-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate)

Structure for NP0168436 ([(2r,3s,4s,5r,6s)-6-[(3s,3'r,3ar,6s,6ar)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-dihydro-5h-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate)

3D Structure for NP0168436 ([(2r,3s,4s,5r,6s)-6-[(3s,3'r,3ar,6s,6ar)-6-(acetyloxy)-3'-(4-hydroxyphenyl)-dihydro-5h-spiro[furo[3,2-b]furan-3,2'-oxolane]-2,5'-dioneoxy]-3,5-bis(acetyloxy)-4-hydroxyoxan-2-yl]methyl acetate)