NP-MRD: Showing NP-Card for (r)-stylopine (NP0164987)

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Record Information

Version

2.0

Created at

2022-09-02 23:59:05 UTC

Updated at

2022-09-02 23:59:05 UTC

NP-MRD ID

NP0164987

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(r)-stylopine

Description

L-Tetrahydrocoptisine, also known as stylopin, belongs to the class of organic compounds known as protoberberine alkaloids and derivatives. These are alkaloids with a structure based on a protoberberine moiety, which consists of a 5,6-dihydrodibenzene moiety fused to a quinolizinium and forming 5,6-Dihydrodibenzo(a,g)quinolizinium skeleton. (r)-stylopine is found in Corydalis intermedia, Corydalis saxicola and Fumaria vaillantii. (r)-stylopine was first documented in 1989 (PMID: 2576175). Based on a literature review very few articles have been published on l-Tetrahydrocoptisine (PMID: 7515744).

Structure

MOL 3D MOL SDF PDB SMILES InChI

     RDKit          3D

 41 46  0  0  0  0  0  0  0  0999 V2000
    2.2840   -2.4424    1.0629 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6654   -2.4437    1.1358 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3716   -1.4338    0.5070 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7444   -0.4236   -0.1915 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3856   -0.4172   -0.2666 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6706   -1.4297    0.3635 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1789   -1.3393    0.2260 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2486    0.0640    0.5022 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.7132    0.1976    0.1784 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5845   -0.8438    0.2135 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9189   -0.6709   -0.0920 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4021    0.5699   -0.4420 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5276    1.6171   -0.4776 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1821    1.4476   -0.1705 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3309    2.6554   -0.2435 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1364    2.3527   -0.1579 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4531    0.9972   -0.2585 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.5821    0.6053   -0.9824 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7737    0.4400   -0.6935 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1865   -0.8164   -0.1816 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9920   -1.5755   -0.1256 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.6708    0.4594   -0.7252 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.9470    0.0489   -0.2976 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7427   -1.1629    0.4000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.6943   -3.2142    1.5408 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2115   -3.2114    1.6702 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1696   -1.6800   -0.7534 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2614   -2.0129    1.0091 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1859    0.2216    1.6056 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2258   -1.8381    0.4882 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9210    2.5879   -0.7545 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6787    3.3362    0.5811 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5928    3.1666   -1.2158 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5486    2.7906    0.7925 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.6453    2.9165   -0.9820 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2496    0.1718   -1.9699 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.2078    1.4978   -1.2183 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.8921   -1.2698   -0.8944 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.6351   -0.6522    0.8186 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.4270    0.8197    0.3372 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6059   -0.0859   -1.1812 H   0  0  0  0  0  0  0  0  0  0  0  0
 20 19  1  0
 19 12  1  0
 12 11  2  0
 11 21  1  0
 11 10  1  0
 10  9  2  0
  9  8  1  0
  8  7  1  0
  7  6  1  0
  6  5  2  0
  5 18  1  0
 18 17  1  0
 17 16  1  0
 16 15  1  0
 15 14  1  0
 14 13  2  0
  5  4  1  0
  4  3  2  0
  3 24  1  0
 24 23  1  0
 23 22  1  0
  3  2  1  0
  2  1  2  0
 21 20  1  0
 14  9  1  0
 22  4  1  0
 13 12  1  0
 17  8  1  0
  1  6  1  0
 20 38  1  0
 20 39  1  0
 10 30  1  0
  8 29  1  1
  7 27  1  0
  7 28  1  0
 18 36  1  0
 18 37  1  0
 16 34  1  0
 16 35  1  0
 15 32  1  0
 15 33  1  0
 13 31  1  0
 23 40  1  0
 23 41  1  0
  2 26  1  0
  1 25  1  0
M  END


  Mrv1652309032201592D          

 24 29  0  0  1  0            999 V2000
    2.2863   -3.2061    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4650   -3.1275    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9863   -3.7994    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3289   -4.5499    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1501   -4.6285    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6288   -3.9566    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4501   -4.0352    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7926   -4.7857    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.6139   -4.8643    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0926   -4.1924    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9138   -4.2709    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2564   -5.0215    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7777   -5.6934    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9565   -5.6148    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4778   -6.2867    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6565   -6.2081    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3140   -5.4576    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.4927   -5.3790    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0760   -4.9276    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.2400   -4.1190    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.5217   -3.7132    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7210   -5.1077    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0027   -4.7018    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1667   -3.8933    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  1  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 11 12  2  0  0  0  0
 12 13  1  0  0  0  0
 13 14  2  0  0  0  0
  9 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
  8 17  1  6  0  0  0
 17 18  1  0  0  0  0
  5 18  1  0  0  0  0
 12 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 11 21  1  0  0  0  0
  4 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
  3 24  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0164987

> <DATABASE_NAME>
NP-MRD

> <SMILES>
C1OC2=C(O1)C=C1[C@H]3CC4=C(CN3CCC1=C2)C1=C(OCO1)C=C4

> <INCHI_IDENTIFIER>
InChI=1S/C19H17NO4/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14/h1-2,6-7,15H,3-5,8-10H2/t15-/m1/s1

> <INCHI_KEY>
UXYJCYXWJGAKQY-OAHLLOKOSA-N

> <FORMULA>
C19H17NO4

> <MOLECULAR_WEIGHT>
323.348

> <EXACT_MASS>
323.115758031

> <JCHEM_ACCEPTOR_COUNT>
5

> <JCHEM_ATOM_COUNT>
41

> <JCHEM_AVERAGE_POLARIZABILITY>
35.01992536616193

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
(1R)-5,7,17,19-tetraoxa-13-azahexacyclo[11.11.0.0^{2,10}.0^{4,8}.0^{15,23}.0^{16,20}]tetracosa-2(10),3,8,15(23),16(20),21-hexaene

> <ALOGPS_LOGP>
2.36

> <JCHEM_LOGP>
3.0251267183333326

> <ALOGPS_LOGS>
-3.27

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
6

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_BASIC>
5.264019913580592

> <JCHEM_POLAR_SURFACE_AREA>
40.160000000000004

> <JCHEM_REFRACTIVITY>
87.03650000000003

> <JCHEM_ROTATABLE_BOND_COUNT>
0

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
1.72e-01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(1R)-5,7,17,19-tetraoxa-13-azahexacyclo[11.11.0.0^{2,10}.0^{4,8}.0^{15,23}.0^{16,20}]tetracosa-2(10),3,8,15(23),16(20),21-hexaene

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 03-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   03-SEP-22         0                                  
HETATM    1  C   UNK     0       4.268  -5.985   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       2.735  -5.838   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       1.841  -7.092   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       2.481  -8.493   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       4.014  -8.640   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       4.907  -7.386   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       6.440  -7.532   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       7.080  -8.933   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       8.613  -9.080   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       9.506  -7.826   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0      11.039  -7.972   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0      11.679  -9.373   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      10.785 -10.628   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       9.252 -10.481   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       8.359 -11.735   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       6.826 -11.589   0.000  0.00  0.00           C+0
HETATM   17  N   UNK     0       6.186 -10.188   0.000  0.00  0.00           N+0
HETATM   18  C   UNK     0       4.653 -10.041   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0      13.209  -9.198   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0      13.515  -7.689   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0      12.174  -6.931   0.000  0.00  0.00           O+0
HETATM   22  O   UNK     0       1.346  -9.534   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0       0.005  -8.777   0.000  0.00  0.00           C+0
HETATM   24  O   UNK     0       0.311  -7.268   0.000  0.00  0.00           O+0
CONECT    1    2    6                                                       
CONECT    2    1    3                                                       
CONECT    3    2    4   24                                                  
CONECT    4    3    5   22                                                  
CONECT    5    4    6   18                                                  
CONECT    6    5    1    7                                                  
CONECT    7    6    8                                                       
CONECT    8    7    9   17                                                  
CONECT    9    8   10   14                                                  
CONECT   10    9   11                                                       
CONECT   11   10   12   21                                                  
CONECT   12   11   13   19                                                  
CONECT   13   12   14                                                       
CONECT   14   13    9   15                                                  
CONECT   15   14   16                                                       
CONECT   16   15   17                                                       
CONECT   17   16    8   18                                                  
CONECT   18   17    5                                                       
CONECT   19   12   20                                                       
CONECT   20   19   21                                                       
CONECT   21   20   11                                                       
CONECT   22    4   23                                                       
CONECT   23   22   24                                                       
CONECT   24   23    3                                                       
MASTER        0    0    0    0    0    0    0    0   24    0   58    0
END

View in JSmol

Synonyms

Value	Source
(12BS)-6,7,12b,13-Tetrahydro-4H-bis(1,3)benzodioxolo(5,6-a:4',5'-g)quinolizine	MeSH
6,7,12b,13-Tetrahydro-4H-bis(1,3)benzodioxolo(5,6-a:4',5'-g)quinolizine	MeSH
Stylopin	MeSH
Stylopine, (S)-isomer	MeSH
(-)-Stylopine	MeSH
Stylopine, 14C-labeled, (+,-)-isomer	MeSH
(+-)-Tetrahydrocoptisine	MeSH
(S)-Stylopine	MeSH
(+-)Stylopine	MeSH
(-)-Tetrahydrocoptisine	MeSH
Stylopine	MeSH
Tetrahydrocoptisine	MeSH

Chemical Formula

C₁₉H₁₇NO₄

Average Mass

323.3480 Da

Monoisotopic Mass

323.11576 Da

IUPAC Name

(1R)-5,7,17,19-tetraoxa-13-azahexacyclo[11.11.0.0^{2,10}.0^{4,8}.0^{15,23}.0^{16,20}]tetracosa-2(10),3,8,15(23),16(20),21-hexaene

Traditional Name

(1R)-5,7,17,19-tetraoxa-13-azahexacyclo[11.11.0.0^{2,10}.0^{4,8}.0^{15,23}.0^{16,20}]tetracosa-2(10),3,8,15(23),16(20),21-hexaene

CAS Registry Number

Not Available

SMILES

C1OC2=C(O1)C=C1[C@H]3CC4=C(CN3CCC1=C2)C1=C(OCO1)C=C4

InChI Identifier

InChI=1S/C19H17NO4/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14/h1-2,6-7,15H,3-5,8-10H2/t15-/m1/s1

InChI Key

UXYJCYXWJGAKQY-OAHLLOKOSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Corydalis intermedia	LOTUS Database	35616633
Corydalis saxicola	LOTUS Database	35616633
Fumaria vaillantii	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as protoberberine alkaloids and derivatives. These are alkaloids with a structure based on a protoberberine moiety, which consists of a 5,6-dihydrodibenzene moiety fused to a quinolizinium and forming 5,6-Dihydrodibenzo(a,g)quinolizinium skeleton.

Kingdom

Organic compounds

Super Class

Alkaloids and derivatives

Class

Protoberberine alkaloids and derivatives

Sub Class

Not Available

Direct Parent

Protoberberine alkaloids and derivatives

Alternative Parents

Substituents

Protoberberine skeleton
Tetrahydroprotoberberine skeleton
Tetrahydroisoquinoline
Benzodioxole
Aralkylamine
Benzenoid
Tertiary amine
Tertiary aliphatic amine
Acetal
Oxacycle
Azacycle
Organoheterocyclic compound
Organopnictogen compound
Organic oxygen compound
Organooxygen compound
Organonitrogen compound
Hydrocarbon derivative
Amine
Organic nitrogen compound
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	2.36	ALOGPS
logP	3.03	ChemAxon
logS	-3.3	ALOGPS
pKa (Strongest Basic)	5.26	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	5	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	40.16 Å²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	87.04 m³·mol⁻¹	ChemAxon
Polarizability	35.02 Å³	ChemAxon
Number of Rings	6	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

C00026095

Chemspider ID

607731

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Tetrahydrocoptisine

METLIN ID

Not Available

PubChem Compound

697545

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Kubo M, Matsuda H, Tokuoka K, Ma S, Shiomoto H: Anti-inflammatory activities of methanolic extract and alkaloidal components from Corydalis tuber. Biol Pharm Bull. 1994 Feb;17(2):262-5. doi: 10.1248/bpb.17.262. [PubMed:7515744 ]
Liu GQ, Han BY, Wang EH: [Blocking actions of l-stephanine, xylopine and 7 other tetrahydroisoquinoline alkaloids on alpha adrenoceptors]. Zhongguo Yao Li Xue Bao. 1989 Jul;10(4):302-6. [PubMed:2576175 ]
LOTUS database [Link]

Showing NP-Card for (r)-stylopine (NP0164987)

MOL for NP0164987 ((r)-stylopine)

3D MOL for NP0164987 ((r)-stylopine)

3D SDF for NP0164987 ((r)-stylopine)

3D-SDF for NP0164987 ((r)-stylopine)

PDB for NP0164987 ((r)-stylopine)

3D PDB for NP0164987 ((r)-stylopine)

SMILES for NP0164987 ((r)-stylopine)

INCHI for NP0164987 ((r)-stylopine)

Structure for NP0164987 ((r)-stylopine)

3D Structure for NP0164987 ((r)-stylopine)