NP-MRD: Showing NP-Card for {7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1h,4ah,5h,6h,7ah-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate (NP0162046)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-02 20:22:39 UTC

Updated at

2022-09-02 20:22:40 UTC

NP-MRD ID

NP0162046

Secondary Accession Numbers

None

Natural Product Identification

Common Name

{7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1h,4ah,5h,6h,7ah-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate

Description

{7-[(Acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate belongs to the class of organic compounds known as iridoids and derivatives. These are monoterpenes containing a skeleton structurally characterized by the presence of a cylopentane fused to a pyran ( forming a 4,7-dimethylcyclopenta[c]pyran), or a derivative where the pentane moiety is open. {7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1h,4ah,5h,6h,7ah-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate is found in Valeriana jatamansi. {7-[(Acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004261501102D          

 31 32  0  0  0  0            999 V2000
   -2.8579   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    3.3000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    3.3000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2136   -0.2549    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6985    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5235    0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.2136    1.0799    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8208    1.6384    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.0505    1.8887    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6693    2.4342    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.5063    3.2430    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7244    3.5061    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.1251    3.7886    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  2  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  5  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  2  0  0  0  0
 14 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 17 19  1  0  0  0  0
 12 20  1  0  0  0  0
 20 21  1  0  0  0  0
  9 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 23 25  1  0  0  0  0
 20 25  1  0  0  0  0
 25 26  1  0  0  0  0
 25 27  1  0  0  0  0
 27 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  2  0  0  0  0
 29 31  1  0  0  0  0
M  END

     RDKit          3D

 65 66  0  0  0  0  0  0  0  0999 V2000
   -3.4298    5.5134    0.2828 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2355    4.1484    0.8277 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9627    3.7782    1.7786 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2920    3.2573    0.3421 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1477    1.9523    0.9055 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0381    1.2783    0.1319 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.3609    1.1971   -1.1961 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.2161    2.1428    0.2183 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.1786    2.7540    1.4756 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.3913    1.1563    0.1374 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7543   -0.1983   -0.0377 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.4713   -1.2794    0.6761 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8891   -1.2662    1.0119 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6728   -1.1669   -0.1764 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0615   -1.1346   -0.1214 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5842   -1.1958    1.0048 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.9100   -1.0327   -1.3272 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.3537   -1.0213   -0.9032 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.5879    0.1629   -0.0037 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.2778   -0.9636   -2.0828 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7204   -2.3253    1.0181 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6184   -2.3226    0.6935 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4222   -1.1344    0.7881 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.4134   -1.2334   -0.1816 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7613   -1.4024    0.0826 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0981   -1.4696    1.2893 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.8037   -1.5061   -0.9541 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1514   -1.6847   -0.2937 C   0  0  0  0  0  0  0  0  0  0  0  0
   -7.2236   -1.7913   -1.3754 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1915   -2.8830    0.6096 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5470    0.0230    0.7492 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.5327    5.7245    0.3414 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1525    5.5588   -0.7986 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9040    6.2419    0.9031 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9084    2.0573    1.9713 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1101    1.4353    0.7031 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2626    0.8751   -1.3923 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2676    2.8845   -0.5952 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.6790    3.5996    1.5063 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9455    1.2188    1.0901 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.0458    1.4212   -0.7118 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5549   -0.4618   -1.0774 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.1619   -2.2063    1.5212 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.1922   -0.4314    1.6740 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.7408   -1.8783   -2.0245 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.6964   -0.0699   -1.8502 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.5830   -1.9358   -0.2945 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.0232   -0.1287    0.9794 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6490    0.7450    0.1365 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.3036    0.8424   -0.4870 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.8134   -0.3883   -2.8825 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.4421   -2.0160   -2.4422 H   0  0  0  0  0  0  0  0  0  0  0  0
    9.2476   -0.5540   -1.7210 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1178   -3.1821    1.5427 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9025   -1.2146    1.8064 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6424   -2.3565   -1.6469 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.8031   -0.5539   -1.5345 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4294   -0.8021    0.3272 H   0  0  0  0  0  0  0  0  0  0  0  0
   -8.0900   -2.3147   -0.9207 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.5005   -0.7637   -1.6542 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.7674   -2.3598   -2.2111 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3389   -3.5628    0.4051 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1469   -2.6070    1.6966 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.1460   -3.4403    0.4824 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1982    0.2714    1.7880 H   0  0  0  0  0  0  0  0  0  0  0  0
 19 18  1  0
 18 20  1  0
 18 17  1  0
 17 15  1  0
 15 16  2  0
 15 14  1  0
 14 13  1  0
 13 12  1  0
 12 21  2  0
 21 22  1  0
 22 23  1  0
 23 24  1  0
 24 25  1  0
 25 26  2  0
 25 27  1  0
 27 28  1  0
 28 29  1  0
 28 30  1  0
 23 31  1  0
 31 11  1  0
 11 10  1  0
 10  8  1  0
  8  9  1  0
  8  6  1  0
  6  7  1  6
  6  5  1  0
  5  4  1  0
  4  2  1  0
  2  1  1  0
  2  3  2  0
 11 12  1  0
  6 31  1  0
 19 48  1  0
 19 49  1  0
 19 50  1  0
 18 47  1  0
 20 51  1  0
 20 52  1  0
 20 53  1  0
 17 45  1  0
 17 46  1  0
 13 43  1  0
 13 44  1  0
 21 54  1  0
 23 55  1  1
 27 56  1  0
 27 57  1  0
 28 58  1  0
 29 59  1  0
 29 60  1  0
 29 61  1  0
 30 62  1  0
 30 63  1  0
 30 64  1  0
 31 65  1  1
 11 42  1  6
 10 40  1  0
 10 41  1  0
  8 38  1  6
  9 39  1  0
  7 37  1  0
  5 35  1  0
  5 36  1  0
  1 32  1  0
  1 33  1  0
  1 34  1  0
M  END


  Mrv1533004261501102D          

 31 32  0  0  0  0            999 V2000
   -2.8579   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    3.3000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    3.3000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2136   -0.2549    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6985    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5235    0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.2136    1.0799    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8208    1.6384    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.0505    1.8887    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6693    2.4342    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.5063    3.2430    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7244    3.5061    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.1251    3.7886    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  2  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  5  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  2  0  0  0  0
 14 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 17 19  1  0  0  0  0
 12 20  1  0  0  0  0
 20 21  1  0  0  0  0
  9 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 23 25  1  0  0  0  0
 20 25  1  0  0  0  0
 25 26  1  0  0  0  0
 25 27  1  0  0  0  0
 27 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  2  0  0  0  0
 29 31  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0162046

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(C)CC(=O)OCC1=COC(OC(=O)CC(C)C)C2C1CC(O)C2(O)COC(C)=O

> <INCHI_IDENTIFIER>
InChI=1S/C22H34O9/c1-12(2)6-18(25)28-9-15-10-29-21(31-19(26)7-13(3)4)20-16(15)8-17(24)22(20,27)11-30-14(5)23/h10,12-13,16-17,20-21,24,27H,6-9,11H2,1-5H3

> <INCHI_KEY>
XMMXYMRDMCRIGT-UHFFFAOYSA-N

> <FORMULA>
C22H34O9

> <MOLECULAR_WEIGHT>
442.505

> <EXACT_MASS>
442.220282675

> <JCHEM_ACCEPTOR_COUNT>
6

> <JCHEM_ATOM_COUNT>
65

> <JCHEM_AVERAGE_POLARIZABILITY>
46.903692542732486

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
2

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
{7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate

> <ALOGPS_LOGP>
1.53

> <JCHEM_LOGP>
1.3244919033333324

> <ALOGPS_LOGS>
-2.78

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
14.704664449716116

> <JCHEM_PKA_STRONGEST_ACIDIC>
12.6630062307642

> <JCHEM_PKA_STRONGEST_BASIC>
-3.2836869753009985

> <JCHEM_POLAR_SURFACE_AREA>
128.59

> <JCHEM_REFRACTIVITY>
108.068

> <JCHEM_ROTATABLE_BOND_COUNT>
12

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
7.32e-01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
{7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1H,4aH,5H,6H,7aH-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 26-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   26-APR-15         0                                  
HETATM    1  C   UNK     0      -5.335  -3.080   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -4.001  -2.310   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -4.001  -0.770   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -2.667  -3.080   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -1.334  -2.310   0.000  0.00  0.00           C+0
HETATM    6  O   UNK     0      -1.334  -0.770   0.000  0.00  0.00           O+0
HETATM    7  O   UNK     0       0.000  -3.080   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0       1.334  -2.310   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       1.334  -0.770   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      -0.000   0.000   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0      -0.000   1.540   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0       1.334   2.310   0.000  0.00  0.00           C+0
HETATM   13  O   UNK     0       1.334   3.850   0.000  0.00  0.00           O+0
HETATM   14  C   UNK     0      -0.000   4.620   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0      -0.000   6.160   0.000  0.00  0.00           O+0
HETATM   16  C   UNK     0      -1.334   3.850   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0      -2.667   4.620   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      -4.001   3.850   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      -2.667   6.160   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       2.667   1.540   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       2.667   0.000   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       4.132  -0.476   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       5.037   0.770   0.000  0.00  0.00           C+0
HETATM   24  O   UNK     0       6.577   0.770   0.000  0.00  0.00           O+0
HETATM   25  C   UNK     0       4.132   2.016   0.000  0.00  0.00           C+0
HETATM   26  O   UNK     0       5.266   3.058   0.000  0.00  0.00           O+0
HETATM   27  C   UNK     0       3.828   3.526   0.000  0.00  0.00           C+0
HETATM   28  O   UNK     0       4.983   4.544   0.000  0.00  0.00           O+0
HETATM   29  C   UNK     0       4.678   6.054   0.000  0.00  0.00           C+0
HETATM   30  O   UNK     0       3.219   6.545   0.000  0.00  0.00           O+0
HETATM   31  C   UNK     0       5.834   7.072   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3    4                                                  
CONECT    3    2                                                            
CONECT    4    2    5                                                       
CONECT    5    4    6    7                                                  
CONECT    6    5                                                            
CONECT    7    5    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8   10   21                                                  
CONECT   10    9   11                                                       
CONECT   11   10   12                                                       
CONECT   12   11   13   20                                                  
CONECT   13   12   14                                                       
CONECT   14   13   15   16                                                  
CONECT   15   14                                                            
CONECT   16   14   17                                                       
CONECT   17   16   18   19                                                  
CONECT   18   17                                                            
CONECT   19   17                                                            
CONECT   20   12   21   25                                                  
CONECT   21   20    9   22                                                  
CONECT   22   21   23                                                       
CONECT   23   22   24   25                                                  
CONECT   24   23                                                            
CONECT   25   23   20   26   27                                             
CONECT   26   25                                                            
CONECT   27   25   28                                                       
CONECT   28   27   29                                                       
CONECT   29   28   30   31                                                  
CONECT   30   29                                                            
CONECT   31   29                                                            
MASTER        0    0    0    0    0    0    0    0   31    0   64    0
END

View in JSmol

Synonyms

Value	Source
{7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1H,4ah,5H,6H,7H,7ah-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoic acid	Generator

Chemical Formula

C₂₂H₃₄O₉

Average Mass

442.5050 Da

Monoisotopic Mass

442.22028 Da

IUPAC Name

{7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate

Traditional Name

{7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1H,4aH,5H,6H,7aH-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate

CAS Registry Number

Not Available

SMILES

CC(C)CC(=O)OCC1=COC(OC(=O)CC(C)C)C2C1CC(O)C2(O)COC(C)=O

InChI Identifier

InChI=1S/C22H34O9/c1-12(2)6-18(25)28-9-15-10-29-21(31-19(26)7-13(3)4)20-16(15)8-17(24)22(20,27)11-30-14(5)23/h10,12-13,16-17,20-21,24,27H,6-9,11H2,1-5H3

InChI Key

XMMXYMRDMCRIGT-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Valeriana jatamansi	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as iridoids and derivatives. These are monoterpenes containing a skeleton structurally characterized by the presence of a cylopentane fused to a pyran ( forming a 4,7-dimethylcyclopenta[c]pyran), or a derivative where the pentane moiety is open.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Monoterpenoids

Direct Parent

Iridoids and derivatives

Alternative Parents

Substituents

Iridoid-skeleton
Bicyclic monoterpenoid
Tricarboxylic acid or derivatives
Fatty acid ester
Fatty acyl
Cyclic alcohol
Tertiary alcohol
1,2-diol
Carboxylic acid ester
Secondary alcohol
Acetal
Carboxylic acid derivative
Oxacycle
Organoheterocyclic compound
Organic oxygen compound
Carbonyl group
Organic oxide
Hydrocarbon derivative
Alcohol
Organooxygen compound
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	1.53	ALOGPS
logP	1.32	ChemAxon
logS	-2.8	ALOGPS
pKa (Strongest Acidic)	12.66	ChemAxon
pKa (Strongest Basic)	-3.3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	6	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	128.59 Å²	ChemAxon
Rotatable Bond Count	12	ChemAxon
Refractivity	108.07 m³·mol⁻¹	ChemAxon
Polarizability	46.9 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

56663817

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for {7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1h,4ah,5h,6h,7ah-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate (NP0162046)

MOL for NP0162046 ({7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1h,4ah,5h,6h,7ah-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate)

3D MOL for NP0162046 ({7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1h,4ah,5h,6h,7ah-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate)

3D SDF for NP0162046 ({7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1h,4ah,5h,6h,7ah-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate)

3D-SDF for NP0162046 ({7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1h,4ah,5h,6h,7ah-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate)

PDB for NP0162046 ({7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1h,4ah,5h,6h,7ah-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate)

3D PDB for NP0162046 ({7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1h,4ah,5h,6h,7ah-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate)

SMILES for NP0162046 ({7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1h,4ah,5h,6h,7ah-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate)

INCHI for NP0162046 ({7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1h,4ah,5h,6h,7ah-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate)

Structure for NP0162046 ({7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1h,4ah,5h,6h,7ah-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate)

3D Structure for NP0162046 ({7-[(acetyloxy)methyl]-6,7-dihydroxy-1-[(3-methylbutanoyl)oxy]-1h,4ah,5h,6h,7ah-cyclopenta[c]pyran-4-yl}methyl 3-methylbutanoate)