NP-MRD: Showing NP-Card for 13-hydroxy-6,14-dimethoxy-7-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione (NP0152741)

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Record Information

Version

2.0

Created at

2022-09-02 09:16:30 UTC

Updated at

2022-09-02 09:16:30 UTC

NP-MRD ID

NP0152741

Secondary Accession Numbers

None

Natural Product Identification

Common Name

13-hydroxy-6,14-dimethoxy-7-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione

Description

4',6,6'-Trihydroxy-4,5'-dimethoxy-5-(beta-D-xylopyranosyloxy)biphenyl-2,2'-dicarboxylic acid 2,6':2',6-Dilactone belongs to the class of organic compounds known as hydrolyzable tannins. These are tannins with a structure characterized by either of the following models. In model 1, the structure contains galloyl units (in some cases, shikimic acid units) that are linked to diverse polyol carbohydrate-, catechin-, or triterpenoid units. In model 2, contains at least two galloyl units C-C coupled to each other, and do not contain a glycosidically linked catechin unit. 13-hydroxy-6,14-dimethoxy-7-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione is found in Terminalia superba. Based on a literature review very few articles have been published on 4',6,6'-Trihydroxy-4,5'-dimethoxy-5-(beta-D-xylopyranosyloxy)biphenyl-2,2'-dicarboxylic acid 2,6':2',6-Dilactone.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309022211162D          

 33 37  0  0  1  0            999 V2000
    5.9664   -1.5395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5539   -0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.7289   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3164   -1.5395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4914   -1.5395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0789   -2.2539    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4914   -2.9684    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.2539   -2.2539    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8414   -1.5395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0164   -1.5395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6039   -2.2539    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2211   -2.2539    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6039   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2211   -0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0164   -0.1105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8414   -0.1105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2539    0.6039    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8414    1.3184    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.0789    0.6039    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.4914   -0.1105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3164   -0.1105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7289    0.6039    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.5539    0.6039    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.9664   -0.1105    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.7914   -0.1105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.2039    0.6039    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    8.0289    0.6039    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.7914    1.3184    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    7.2039    2.0329    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.9664    1.3184    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.5539    2.0329    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.0789   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2539   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  2  0  0  0  0
  5  6  1  0  0  0  0
  6  7  2  0  0  0  0
  6  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 10 13  1  0  0  0  0
 13 14  1  0  0  0  0
 13 15  2  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  2  0  0  0  0
 17 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
  3 21  2  0  0  0  0
 21 22  1  0  0  0  0
 23 22  1  1  0  0  0
 23 24  1  0  0  0  0
 24 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  6  0  0  0
 26 28  1  0  0  0  0
 28 29  1  1  0  0  0
 28 30  1  0  0  0  0
 23 30  1  0  0  0  0
 30 31  1  6  0  0  0
 20 32  2  0  0  0  0
  5 32  1  0  0  0  0
 32 33  1  0  0  0  0
  9 33  1  0  0  0  0
 16 33  2  0  0  0  0
M  END

     RDKit          3D

 51 55  0  0  0  0  0  0  0  0999 V2000
    1.7105    0.6074   -4.2288 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8491    0.3225   -2.8577 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7315    0.1269   -2.0827 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5314    0.2002   -2.6044 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6357    0.0039   -1.8247 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9257    0.0689   -2.3104 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0396    0.3277   -3.5546 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9735   -0.1229   -1.5444 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8642   -0.3896   -0.2631 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9445   -0.5923    0.5506 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.2140   -0.5143    0.0056 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.9222    0.7148   -0.0335 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7611   -0.8712    1.8993 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8820   -1.0700    2.6890 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4888   -0.9496    2.4466 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3944   -0.7474    1.6374 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0972   -0.8116    2.1203 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9606   -1.0666    3.3495 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0563   -0.6167    1.3382 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1850   -0.3501    0.0550 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9351   -0.1510   -0.7357 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2213   -0.2219   -0.2222 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8159    0.9690    0.2875 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.0010    1.2606   -0.4148 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.7933    0.1356   -0.5243 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.1314   -0.5166    0.7683 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.3135   -0.0390    1.3344 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.0594   -0.4712    1.8013 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.1741   -1.5631    1.7113 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.2361    0.7975    1.7369 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.1051    1.8525    2.0388 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4527   -0.2752   -0.4744 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5880   -0.4697    0.2923 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7112    0.8520   -4.6686 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.3294   -0.3155   -4.7134 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.9770    1.4113   -4.4182 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7046    0.4181   -3.6626 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.7205    0.6774   -0.8061 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.4299    0.9395    0.9298 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.2481    1.5588   -0.3457 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.7991   -1.0138    2.2962 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3808   -1.1669    3.4930 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1495    1.8323    0.2057 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.3201   -0.5354   -1.2643 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.7555    0.4690   -0.9961 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3295   -1.6073    0.5485 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.8628    0.4706    0.6864 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.5023   -0.5107    2.8249 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3064   -2.0465    0.8404 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.3895    0.7289    2.4252 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.4891    2.2609    1.2251 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3 21  2  0
 21 22  1  0
 22 23  1  0
 23 24  1  0
 24 25  1  0
 25 26  1  0
 26 27  1  0
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 28 29  1  0
 28 30  1  0
 30 31  1  0
 21 20  1  0
 20 32  2  0
 32  5  1  0
  5  4  2  0
  5  6  1  0
  6  7  2  0
  6  8  1  0
  8  9  1  0
  9 10  2  0
 10 11  1  0
 11 12  1  0
 10 13  1  0
 13 14  1  0
 13 15  2  0
 15 16  1  0
 16 17  1  0
 17 18  2  0
 17 19  1  0
 16 33  2  0
  4  3  1  0
 33  9  1  0
 30 23  1  0
 19 20  1  0
 33 32  1  0
  1 34  1  0
  1 35  1  0
  1 36  1  0
 23 43  1  1
 25 44  1  0
 25 45  1  0
 26 46  1  6
 27 47  1  0
 28 48  1  1
 29 49  1  0
 30 50  1  1
 31 51  1  0
  4 37  1  0
 12 38  1  0
 12 39  1  0
 12 40  1  0
 14 41  1  0
 15 42  1  0
M  END


  Mrv1652309022211162D          

 33 37  0  0  1  0            999 V2000
    5.9664   -1.5395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5539   -0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.7289   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3164   -1.5395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4914   -1.5395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0789   -2.2539    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4914   -2.9684    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.2539   -2.2539    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8414   -1.5395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0164   -1.5395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6039   -2.2539    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2211   -2.2539    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6039   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2211   -0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0164   -0.1105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8414   -0.1105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2539    0.6039    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8414    1.3184    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.0789    0.6039    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.4914   -0.1105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3164   -0.1105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7289    0.6039    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.5539    0.6039    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.9664   -0.1105    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.7914   -0.1105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.2039    0.6039    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    8.0289    0.6039    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.7914    1.3184    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    7.2039    2.0329    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.9664    1.3184    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.5539    2.0329    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.0789   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2539   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  2  0  0  0  0
  5  6  1  0  0  0  0
  6  7  2  0  0  0  0
  6  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 10 13  1  0  0  0  0
 13 14  1  0  0  0  0
 13 15  2  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  2  0  0  0  0
 17 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
  3 21  2  0  0  0  0
 21 22  1  0  0  0  0
 23 22  1  1  0  0  0
 23 24  1  0  0  0  0
 24 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  6  0  0  0
 26 28  1  0  0  0  0
 28 29  1  1  0  0  0
 28 30  1  0  0  0  0
 23 30  1  0  0  0  0
 30 31  1  6  0  0  0
 20 32  2  0  0  0  0
  5 32  1  0  0  0  0
 32 33  1  0  0  0  0
  9 33  1  0  0  0  0
 16 33  2  0  0  0  0
M  END
> <DATABASE_ID>
NP0152741

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC1=C(O[C@@H]2OC[C@@H](O)[C@H](O)[C@H]2O)C2=C3C(=C1)C(=O)OC1=C(OC)C(O)=CC(C(=O)O2)=C31

> <INCHI_IDENTIFIER>
InChI=1S/C21H18O12/c1-28-10-4-7-12-11-6(3-8(22)15(29-2)17(11)31-20(7)27)19(26)32-18(12)16(10)33-21-14(25)13(24)9(23)5-30-21/h3-4,9,13-14,21-25H,5H2,1-2H3/t9-,13+,14-,21+/m1/s1

> <INCHI_KEY>
ZCQGHISGOMVSGJ-LAPUEANGSA-N

> <FORMULA>
C21H18O12

> <MOLECULAR_WEIGHT>
462.363

> <EXACT_MASS>
462.07982602

> <JCHEM_ACCEPTOR_COUNT>
10

> <JCHEM_ATOM_COUNT>
51

> <JCHEM_AVERAGE_POLARIZABILITY>
43.04279951782398

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
4

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
6-hydroxy-7,13-dimethoxy-14-{[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione

> <ALOGPS_LOGP>
0.53

> <JCHEM_LOGP>
-0.3300226213333333

> <ALOGPS_LOGS>
-2.56

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA>
12.234745672878496

> <JCHEM_PKA_STRONGEST_ACIDIC>
6.176445239614781

> <JCHEM_PKA_STRONGEST_BASIC>
-3.5265985443357293

> <JCHEM_POLAR_SURFACE_AREA>
170.44

> <JCHEM_REFRACTIVITY>
105.75410000000001

> <JCHEM_ROTATABLE_BOND_COUNT>
4

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
1.29e+00 g/l

> <JCHEM_TRADITIONAL_IUPAC>
6-hydroxy-7,13-dimethoxy-14-{[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 02-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   02-SEP-22         0                                  
HETATM    1  C   UNK     0      11.137  -2.874   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0      10.367  -1.540   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0       8.827  -1.540   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       8.057  -2.874   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       6.517  -2.874   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       5.747  -4.207   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0       6.517  -5.541   0.000  0.00  0.00           O+0
HETATM    8  O   UNK     0       4.207  -4.207   0.000  0.00  0.00           O+0
HETATM    9  C   UNK     0       3.437  -2.874   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       1.897  -2.874   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0       1.127  -4.207   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0      -0.413  -4.207   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       1.127  -1.540   0.000  0.00  0.00           C+0
HETATM   14  O   UNK     0      -0.413  -1.540   0.000  0.00  0.00           O+0
HETATM   15  C   UNK     0       1.897  -0.206   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       3.437  -0.206   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       4.207   1.127   0.000  0.00  0.00           C+0
HETATM   18  O   UNK     0       3.437   2.461   0.000  0.00  0.00           O+0
HETATM   19  O   UNK     0       5.747   1.127   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0       6.517  -0.206   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       8.057  -0.206   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0       8.827   1.127   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0      10.367   1.127   0.000  0.00  0.00           C+0
HETATM   24  O   UNK     0      11.137  -0.206   0.000  0.00  0.00           O+0
HETATM   25  C   UNK     0      12.677  -0.206   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0      13.447   1.127   0.000  0.00  0.00           C+0
HETATM   27  O   UNK     0      14.987   1.127   0.000  0.00  0.00           O+0
HETATM   28  C   UNK     0      12.677   2.461   0.000  0.00  0.00           C+0
HETATM   29  O   UNK     0      13.447   3.795   0.000  0.00  0.00           O+0
HETATM   30  C   UNK     0      11.137   2.461   0.000  0.00  0.00           C+0
HETATM   31  O   UNK     0      10.367   3.795   0.000  0.00  0.00           O+0
HETATM   32  C   UNK     0       5.747  -1.540   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0       4.207  -1.540   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4   21                                                  
CONECT    4    3    5                                                       
CONECT    5    4    6   32                                                  
CONECT    6    5    7    8                                                  
CONECT    7    6                                                            
CONECT    8    6    9                                                       
CONECT    9    8   10   33                                                  
CONECT   10    9   11   13                                                  
CONECT   11   10   12                                                       
CONECT   12   11                                                            
CONECT   13   10   14   15                                                  
CONECT   14   13                                                            
CONECT   15   13   16                                                       
CONECT   16   15   17   33                                                  
CONECT   17   16   18   19                                                  
CONECT   18   17                                                            
CONECT   19   17   20                                                       
CONECT   20   19   21   32                                                  
CONECT   21   20    3   22                                                  
CONECT   22   21   23                                                       
CONECT   23   22   24   30                                                  
CONECT   24   23   25                                                       
CONECT   25   24   26                                                       
CONECT   26   25   27   28                                                  
CONECT   27   26                                                            
CONECT   28   26   29   30                                                  
CONECT   29   28                                                            
CONECT   30   28   23   31                                                  
CONECT   31   30                                                            
CONECT   32   20    5   33                                                  
CONECT   33   32    9   16                                                  
MASTER        0    0    0    0    0    0    0    0   33    0   74    0
END

View in JSmol

Synonyms

Value	Source
4',6,6'-Trihydroxy-4,5'-dimethoxy-5-(b-D-xylopyranosyloxy)biphenyl-2,2'-dicarboxylate 2,6':2',6-dilactone	Generator
4',6,6'-Trihydroxy-4,5'-dimethoxy-5-(b-D-xylopyranosyloxy)biphenyl-2,2'-dicarboxylic acid 2,6':2',6-dilactone	Generator
4',6,6'-Trihydroxy-4,5'-dimethoxy-5-(beta-D-xylopyranosyloxy)biphenyl-2,2'-dicarboxylate 2,6':2',6-dilactone	Generator
4',6,6'-Trihydroxy-4,5'-dimethoxy-5-(β-D-xylopyranosyloxy)biphenyl-2,2'-dicarboxylate 2,6':2',6-dilactone	Generator
4',6,6'-Trihydroxy-4,5'-dimethoxy-5-(β-D-xylopyranosyloxy)biphenyl-2,2'-dicarboxylic acid 2,6':2',6-dilactone	Generator

Chemical Formula

C₂₁H₁₈O₁₂

Average Mass

462.3630 Da

Monoisotopic Mass

462.07983 Da

IUPAC Name

6-hydroxy-7,13-dimethoxy-14-{[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione

Traditional Name

6-hydroxy-7,13-dimethoxy-14-{[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione

CAS Registry Number

Not Available

SMILES

COC1=C(O[C@@H]2OC[C@@H](O)[C@H](O)[C@H]2O)C2=C3C(=C1)C(=O)OC1=C(OC)C(O)=CC(C(=O)O2)=C31

InChI Identifier

InChI=1S/C21H18O12/c1-28-10-4-7-12-11-6(3-8(22)15(29-2)17(11)31-20(7)27)19(26)32-18(12)16(10)33-21-14(25)13(24)9(23)5-30-21/h3-4,9,13-14,21-25H,5H2,1-2H3/t9-,13+,14-,21+/m1/s1

InChI Key

ZCQGHISGOMVSGJ-LAPUEANGSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Terminalia superba	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as hydrolyzable tannins. These are tannins with a structure characterized by either of the following models. In model 1, the structure contains galloyl units (in some cases, shikimic acid units) that are linked to diverse polyol carbohydrate-, catechin-, or triterpenoid units. In model 2, contains at least two galloyl units C-C coupled to each other, and do not contain a glycosidically linked catechin unit.

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Tannins

Sub Class

Hydrolyzable tannins

Direct Parent

Hydrolyzable tannins

Alternative Parents

Substituents

Hydrolyzable tannin
Ellagic_acid
Phenolic glycoside
Isocoumarin
Coumarin
O-glycosyl compound
Glycosyl compound
Benzopyran
2-benzopyran
1-benzopyran
Anisole
1-hydroxy-2-unsubstituted benzenoid
Alkyl aryl ether
Pyranone
Monosaccharide
Benzenoid
Oxane
Pyran
Heteroaromatic compound
Secondary alcohol
Lactone
Acetal
Oxacycle
Organoheterocyclic compound
Ether
Polyol
Hydrocarbon derivative
Alcohol
Organic oxygen compound
Organic oxide
Organooxygen compound
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	0.53	ALOGPS
logP	-0.33	ChemAxon
logS	-2.6	ALOGPS
pKa (Strongest Acidic)	6.18	ChemAxon
pKa (Strongest Basic)	-3.5	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	10	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	170.44 Å²	ChemAxon
Rotatable Bond Count	4	ChemAxon
Refractivity	105.75 m³·mol⁻¹	ChemAxon
Polarizability	43.04 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

25014727

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 13-hydroxy-6,14-dimethoxy-7-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione (NP0152741)

MOL for NP0152741 (13-hydroxy-6,14-dimethoxy-7-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione)

3D MOL for NP0152741 (13-hydroxy-6,14-dimethoxy-7-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione)

3D SDF for NP0152741 (13-hydroxy-6,14-dimethoxy-7-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione)

3D-SDF for NP0152741 (13-hydroxy-6,14-dimethoxy-7-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione)

PDB for NP0152741 (13-hydroxy-6,14-dimethoxy-7-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione)

3D PDB for NP0152741 (13-hydroxy-6,14-dimethoxy-7-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione)

SMILES for NP0152741 (13-hydroxy-6,14-dimethoxy-7-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione)

INCHI for NP0152741 (13-hydroxy-6,14-dimethoxy-7-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione)

Structure for NP0152741 (13-hydroxy-6,14-dimethoxy-7-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione)

3D Structure for NP0152741 (13-hydroxy-6,14-dimethoxy-7-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione)