NP-MRD: Showing NP-Card for methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylate (NP0149055)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-02 04:53:09 UTC

Updated at

2022-09-02 04:53:09 UTC

NP-MRD ID

NP0149055

Secondary Accession Numbers

None

Natural Product Identification

Common Name

methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylate

Description

Methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units. methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylate is found in Kalidium foliatum. Methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004161518322D          

 36 40  0  0  0  0            999 V2000
   -0.5230   -6.6809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1105   -5.9664    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1270   -6.6809    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.1270   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3020   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1105   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3020   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4452   -3.0106    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4733   -3.5409    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6165   -2.7284    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.1270   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7770   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6020   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0145   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8395   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4270   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2520   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0770   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4895   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.3145   -4.5375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.0770   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9337   -6.0644    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8522   -5.5341    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.9955   -6.3466    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.2520   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8395   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0145   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6020   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1895   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7770   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6907   -6.0725    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  3  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  8 10  1  0  0  0  0
 10 11  1  0  0  0  0
  8 12  1  0  0  0  0
 12 13  1  0  0  0  0
  5 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  2  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 22 24  1  0  0  0  0
 24 25  1  0  0  0  0
 24 26  1  0  0  0  0
 26 27  1  0  0  0  0
 24 28  1  0  0  0  0
 18 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  1  0  0  0  0
 30 31  1  0  0  0  0
 17 31  1  0  0  0  0
 31 32  1  0  0  0  0
 31 33  1  0  0  0  0
 14 33  1  0  0  0  0
 33 34  1  0  0  0  0
 33 35  1  0  0  0  0
 35 36  1  0  0  0  0
  5 36  1  0  0  0  0
M  END

     RDKit          3D

 86 90  0  0  0  0  0  0  0  0999 V2000
   -4.4184    3.6027   -1.6477 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6412    2.4429   -1.4232 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3081    1.2344   -1.2884 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5473    1.1933   -1.3654 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5583   -0.0603   -1.0478 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.7998   -0.3093   -2.2800 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3392   -0.2951   -2.3702 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6156   -0.5351   -1.0301 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.8651   -2.0217   -0.7992 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3850    0.3288   -0.1280 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8623    1.4076    0.3562 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5261    1.8519    0.0845 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3113    0.5233    0.0570 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.7326    0.7745    0.3387 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.8543    0.9181    1.8707 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3259    2.0474   -0.2072 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7069    2.2117    0.3008 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5893    1.0705    0.5062 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.7538    1.2147   -0.2984 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0203   -0.3108    0.4400 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.9020   -1.0638   -0.5996 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2388   -1.1148    1.6899 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6997   -2.3962    1.6103 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.6616   -0.2922   -0.1313 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.9040   -1.5480   -0.1094 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6984   -1.5867   -1.0354 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8731   -0.3293   -1.0861 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.1306    0.2780   -2.4535 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7748    0.0368    0.2411 C   0  0  2  0  0  0  0  0  0  0  0  0
   -3.0272   -1.0212    1.2235 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4781   -0.7783    1.7157 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.5793    0.5282    2.4358 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7461   -1.9084    2.6965 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0459   -1.9377    3.1326 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3345   -0.9063    0.5083 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6626   -1.0721   -0.8000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7749    4.5002   -1.7416 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.0002    3.5563   -2.5948 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1123    3.7996   -0.7964 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2249    0.3498   -3.1099 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1703   -1.3307   -2.6532 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0236    0.6235   -2.8739 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0345   -1.1358   -3.0654 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9693   -2.2044   -1.0680 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6147   -2.4087    0.1618 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3959   -2.6249   -1.6017 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4305    2.0851    1.0219 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.6356    2.4219   -0.8522 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.9233    2.5071    0.8682 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.9180   -0.0356    0.9438 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.0392    1.6071    2.2520 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.5868   -0.0607    2.3057 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.7656    1.3821    2.2023 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3649    2.0105   -1.3270 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.7184    2.8982    0.0923 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.6541    2.8885    1.2144 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.1985    2.9334   -0.4343 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.0366    1.1586    1.5476 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.5446    0.8445    0.1271 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.7995   -0.6040   -1.5832 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.4787   -2.0899   -0.6440 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.9479   -1.0997   -0.2336 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.8405   -0.6736    2.6190 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.3568   -1.3108    1.7993 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3173   -3.0978    1.8823 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.8779   -0.0281   -1.2197 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.5609   -1.7398    0.9519 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.5036   -2.4566   -0.3688 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1606   -2.4827   -0.6289 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1219   -1.8697   -2.0489 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.8114    1.3352   -2.5327 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.2031    0.2828   -2.7524 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7330   -0.3851   -3.2454 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2245    0.9642    0.7499 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1077   -2.0582    0.9101 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3455   -0.8707    2.0906 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2056    0.4075    3.3355 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9819    1.3595    1.8344 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5534    0.8238    2.8031 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4740   -2.8836    2.2291 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0842   -1.8234    3.5923 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4525   -2.8334    2.9951 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0387   -0.0471    0.4972 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0225   -1.8037    0.6245 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3505   -2.1061   -1.0382 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.4464   -0.8521   -1.5886 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  2  0
  5  3  1  6
  5 36  1  0
 36 35  1  0
 35 31  1  0
 31 32  1  1
 31 33  1  0
 33 34  1  0
 31 30  1  0
 30 29  1  0
 29 10  1  0
 10 11  2  0
 11 12  1  0
 12 13  1  0
 13 14  1  0
 14 15  1  1
 14 16  1  0
 16 17  1  0
 17 18  1  0
 18 19  1  0
 18 20  1  0
 20 21  1  6
 20 22  1  0
 22 23  1  0
 20 24  1  0
 24 25  1  0
 25 26  1  0
 26 27  1  0
 27 28  1  6
 27  8  1  0
  8  9  1  1
  8  7  1  0
  7  6  1  0
 29  5  1  0
  8 10  1  0
  6  5  1  0
 27 13  1  0
 24 14  1  0
  1 37  1  0
  1 38  1  0
  1 39  1  0
 36 85  1  0
 36 86  1  0
 35 83  1  0
 35 84  1  0
 32 77  1  0
 32 78  1  0
 32 79  1  0
 33 80  1  0
 33 81  1  0
 34 82  1  0
 30 75  1  0
 30 76  1  0
 29 74  1  1
 11 47  1  0
 12 48  1  0
 12 49  1  0
 13 50  1  1
 15 51  1  0
 15 52  1  0
 15 53  1  0
 16 54  1  0
 16 55  1  0
 17 56  1  0
 17 57  1  0
 18 58  1  1
 19 59  1  0
 21 60  1  0
 21 61  1  0
 21 62  1  0
 22 63  1  0
 22 64  1  0
 23 65  1  0
 24 66  1  6
 25 67  1  0
 25 68  1  0
 26 69  1  0
 26 70  1  0
 28 71  1  0
 28 72  1  0
 28 73  1  0
  9 44  1  0
  9 45  1  0
  9 46  1  0
  7 42  1  0
  7 43  1  0
  6 40  1  0
  6 41  1  0
M  END


  Mrv1533004161518322D          

 36 40  0  0  0  0            999 V2000
   -0.5230   -6.6809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1105   -5.9664    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1270   -6.6809    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.1270   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3020   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1105   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3020   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4452   -3.0106    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4733   -3.5409    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6165   -2.7284    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.1270   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7770   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6020   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0145   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8395   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4270   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2520   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0770   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4895   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.3145   -4.5375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.0770   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9337   -6.0644    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8522   -5.5341    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.9955   -6.3466    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.2520   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8395   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0145   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6020   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1895   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7770   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6907   -6.0725    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  3  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  8 10  1  0  0  0  0
 10 11  1  0  0  0  0
  8 12  1  0  0  0  0
 12 13  1  0  0  0  0
  5 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  2  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 22 24  1  0  0  0  0
 24 25  1  0  0  0  0
 24 26  1  0  0  0  0
 26 27  1  0  0  0  0
 24 28  1  0  0  0  0
 18 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  1  0  0  0  0
 30 31  1  0  0  0  0
 17 31  1  0  0  0  0
 31 32  1  0  0  0  0
 31 33  1  0  0  0  0
 14 33  1  0  0  0  0
 33 34  1  0  0  0  0
 33 35  1  0  0  0  0
 35 36  1  0  0  0  0
  5 36  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0149055

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC(=O)C12CCC(C)(CO)CC1C1=CCC3C4(C)CCC(O)C(C)(CO)C4CCC3(C)C1(C)CC2

> <INCHI_IDENTIFIER>
InChI=1S/C31H50O5/c1-26(18-32)13-15-31(25(35)36-6)16-14-29(4)20(21(31)17-26)7-8-23-27(2)11-10-24(34)28(3,19-33)22(27)9-12-30(23,29)5/h7,21-24,32-34H,8-19H2,1-6H3

> <INCHI_KEY>
QCYVRROBMNKQIM-UHFFFAOYSA-N

> <FORMULA>
C31H50O5

> <MOLECULAR_WEIGHT>
502.736

> <EXACT_MASS>
502.36582471

> <JCHEM_ACCEPTOR_COUNT>
4

> <JCHEM_ATOM_COUNT>
86

> <JCHEM_AVERAGE_POLARIZABILITY>
58.9034266199435

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
3

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate

> <ALOGPS_LOGP>
4.88

> <JCHEM_LOGP>
4.179185176000001

> <ALOGPS_LOGS>
-5.14

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
15.270342745780184

> <JCHEM_PKA_STRONGEST_ACIDIC>
14.485961382940463

> <JCHEM_PKA_STRONGEST_BASIC>
-1.3618549728061593

> <JCHEM_POLAR_SURFACE_AREA>
86.99000000000001

> <JCHEM_REFRACTIVITY>
141.943

> <JCHEM_ROTATABLE_BOND_COUNT>
4

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
3.65e-03 g/l

> <JCHEM_TRADITIONAL_IUPAC>
methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 16-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   16-APR-15         0                                  
HETATM    1  C   UNK     0      -0.976 -12.471   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0      -0.206 -11.137   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0       1.334 -11.137   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0       2.104 -12.471   0.000  0.00  0.00           O+0
HETATM    5  C   UNK     0       2.104  -9.804   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       0.564  -9.804   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      -0.206  -8.470   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       0.564  -7.136   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       0.831  -5.620   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      -0.883  -6.610   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0      -1.151  -5.093   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0       2.104  -7.136   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       2.874  -8.470   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       4.414  -8.470   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       5.184  -7.136   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       6.724  -7.136   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       7.494  -8.470   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       9.034  -8.470   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       8.264  -7.136   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       9.804  -7.136   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      11.344  -7.136   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      12.114  -8.470   0.000  0.00  0.00           C+0
HETATM   23  O   UNK     0      13.654  -8.470   0.000  0.00  0.00           O+0
HETATM   24  C   UNK     0      11.344  -9.804   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0      11.076 -11.320   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0      12.791 -10.330   0.000  0.00  0.00           C+0
HETATM   27  O   UNK     0      13.058 -11.847   0.000  0.00  0.00           O+0
HETATM   28  C   UNK     0       9.804  -9.804   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       9.034 -11.137   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       7.494 -11.137   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       6.724  -9.804   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       5.954 -11.137   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0       5.184  -9.804   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0       5.023 -11.335   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       4.414 -11.137   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0       2.874 -11.137   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4    5                                                  
CONECT    4    3                                                            
CONECT    5    3    6   13   36                                             
CONECT    6    5    7                                                       
CONECT    7    6    8                                                       
CONECT    8    7    9   10   12                                             
CONECT    9    8                                                            
CONECT   10    8   11                                                       
CONECT   11   10                                                            
CONECT   12    8   13                                                       
CONECT   13   12    5   14                                                  
CONECT   14   13   15   33                                                  
CONECT   15   14   16                                                       
CONECT   16   15   17                                                       
CONECT   17   16   18   31                                                  
CONECT   18   17   19   20   28                                             
CONECT   19   18                                                            
CONECT   20   18   21                                                       
CONECT   21   20   22                                                       
CONECT   22   21   23   24                                                  
CONECT   23   22                                                            
CONECT   24   22   25   26   28                                             
CONECT   25   24                                                            
CONECT   26   24   27                                                       
CONECT   27   26                                                            
CONECT   28   24   18   29                                                  
CONECT   29   28   30                                                       
CONECT   30   29   31                                                       
CONECT   31   30   17   32   33                                             
CONECT   32   31                                                            
CONECT   33   31   14   34   35                                             
CONECT   34   33                                                            
CONECT   35   33   36                                                       
CONECT   36   35    5                                                       
MASTER        0    0    0    0    0    0    0    0   36    0   80    0
END

View in JSmol

Synonyms

Value	Source
Methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid	Generator

Chemical Formula

C₃₁H₅₀O₅

Average Mass

502.7360 Da

Monoisotopic Mass

502.36582 Da

IUPAC Name

methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate

Traditional Name

methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylate

CAS Registry Number

Not Available

SMILES

COC(=O)C12CCC(C)(CO)CC1C1=CCC3C4(C)CCC(O)C(C)(CO)C4CCC3(C)C1(C)CC2

InChI Identifier

InChI=1S/C31H50O5/c1-26(18-32)13-15-31(25(35)36-6)16-14-29(4)20(21(31)17-26)7-8-23-27(2)11-10-24(34)28(3,19-33)22(27)9-12-30(23,29)5/h7,21-24,32-34H,8-19H2,1-6H3

InChI Key

QCYVRROBMNKQIM-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Kalidium foliatum	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Triterpenoids

Direct Parent

Triterpenoids

Alternative Parents

Substituents

Triterpenoid
Steroid
Cyclic alcohol
Methyl ester
Carboxylic acid ester
Secondary alcohol
Monocarboxylic acid or derivatives
Carboxylic acid derivative
Primary alcohol
Organooxygen compound
Organic oxygen compound
Alcohol
Carbonyl group
Organic oxide
Hydrocarbon derivative
Aliphatic homopolycyclic compound

Molecular Framework

Aliphatic homopolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	4.88	ALOGPS
logP	4.18	ChemAxon
logS	-5.1	ALOGPS
pKa (Strongest Acidic)	14.49	ChemAxon
pKa (Strongest Basic)	-1.4	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	4	ChemAxon
Hydrogen Donor Count	3	ChemAxon
Polar Surface Area	86.99 Å²	ChemAxon
Rotatable Bond Count	4	ChemAxon
Refractivity	141.94 m³·mol⁻¹	ChemAxon
Polarizability	58.9 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

74078742

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylate (NP0149055)

MOL for NP0149055 (methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylate)

3D MOL for NP0149055 (methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylate)

3D SDF for NP0149055 (methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylate)

3D-SDF for NP0149055 (methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylate)

PDB for NP0149055 (methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylate)

3D PDB for NP0149055 (methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylate)

SMILES for NP0149055 (methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylate)

INCHI for NP0149055 (methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylate)

Structure for NP0149055 (methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylate)

3D Structure for NP0149055 (methyl 10-hydroxy-2,9-bis(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylate)