Record Information |
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Version | 2.0 |
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Created at | 2022-09-02 02:30:09 UTC |
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Updated at | 2022-09-02 02:30:09 UTC |
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NP-MRD ID | NP0146994 |
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Secondary Accession Numbers | None |
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Natural Product Identification |
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Common Name | 9-methoxy-8-oxa-17-azatetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-1(17),2,4,6,10,15-hexaene-4,14-diol |
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Description | Ganoapplanatumine B belongs to the class of organic compounds known as 1-benzopyrans. These are organic aromatic compounds that 1-benzopyran, a bicyclic compound made up of a benzene ring fused to a pyran, so that the oxygen atom is at the 1-position. 9-methoxy-8-oxa-17-azatetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-1(17),2,4,6,10,15-hexaene-4,14-diol is found in Ganoderma applanatum. It was first documented in 2022 (PMID: 36049892). Based on a literature review a significant number of articles have been published on Ganoapplanatumine B (PMID: 36049848) (PMID: 36049845) (PMID: 36049817) (PMID: 36049782) (PMID: 36049750) (PMID: 36049745). |
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Structure | COC1OC2=CC=C(O)C=C2C2=NC=C3C(O)CCC3=C12 InChI=1S/C16H15NO4/c1-20-16-14-9-3-4-12(19)11(9)7-17-15(14)10-6-8(18)2-5-13(10)21-16/h2,5-7,12,16,18-19H,3-4H2,1H3 |
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Synonyms | Not Available |
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Chemical Formula | C16H15NO4 |
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Average Mass | 285.2990 Da |
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Monoisotopic Mass | 285.10011 Da |
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IUPAC Name | 9-methoxy-8-oxa-17-azatetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1(17),2(7),3,5,10,15-hexaene-4,14-diol |
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Traditional Name | 9-methoxy-8-oxa-17-azatetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1(17),2(7),3,5,10,15-hexaene-4,14-diol |
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CAS Registry Number | Not Available |
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SMILES | COC1OC2=CC=C(O)C=C2C2=NC=C3C(O)CCC3=C12 |
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InChI Identifier | InChI=1S/C16H15NO4/c1-20-16-14-9-3-4-12(19)11(9)7-17-15(14)10-6-8(18)2-5-13(10)21-16/h2,5-7,12,16,18-19H,3-4H2,1H3 |
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InChI Key | VRHKQOAYXJYGPL-UHFFFAOYSA-N |
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Experimental Spectra |
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| Not Available | Predicted Spectra |
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| Spectrum Type | Description | Depositor ID | Depositor Organization | Depositor | Deposition Date | View |
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1D NMR | 13C NMR Spectrum (1D, 25 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 100 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 252 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 1000 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 50 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 200 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 75 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 300 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 101 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 400 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 126 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 500 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 151 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 600 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 176 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 700 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 201 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 800 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 226 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 900 MHz, H2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum |
| Chemical Shift Submissions |
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| Not Available | Species |
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Species of Origin | |
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Chemical Taxonomy |
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Description | Belongs to the class of organic compounds known as 1-benzopyrans. These are organic aromatic compounds that 1-benzopyran, a bicyclic compound made up of a benzene ring fused to a pyran, so that the oxygen atom is at the 1-position. |
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Kingdom | Organic compounds |
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Super Class | Organoheterocyclic compounds |
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Class | Benzopyrans |
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Sub Class | 1-benzopyrans |
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Direct Parent | 1-benzopyrans |
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Alternative Parents | |
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Substituents | - 1-benzopyran
- 1-hydroxy-2-unsubstituted benzenoid
- Benzenoid
- Pyridine
- Heteroaromatic compound
- Secondary alcohol
- Oxacycle
- Azacycle
- Acetal
- Organic nitrogen compound
- Organic oxygen compound
- Organopnictogen compound
- Hydrocarbon derivative
- Organooxygen compound
- Organonitrogen compound
- Alcohol
- Aromatic heteropolycyclic compound
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Molecular Framework | Aromatic heteropolycyclic compounds |
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External Descriptors | Not Available |
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Physical Properties |
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State | Not Available |
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Experimental Properties | Property | Value | Reference |
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Melting Point | Not Available | Not Available | Boiling Point | Not Available | Not Available | Water Solubility | Not Available | Not Available | LogP | Not Available | Not Available |
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Predicted Properties | |
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General References | - Xiang R, Li M, Gu Z, Liu H, Zeng H, Peng J: Chronic endometritis positively correlates with the aggravation of intrauterine adhesions but has limited effects on reproductive prognosis with antibiotic application. Int J Gynaecol Obstet. 2022 Sep 1. doi: 10.1002/ijgo.14434. [PubMed:36049892 ]
- Gilles H, Garbutt T, Landrum J: Hepatocellular Carcinoma. Crit Care Nurs Clin North Am. 2022 Sep;34(3):289-301. doi: 10.1016/j.cnc.2022.04.004. Epub 2022 Jul 20. [PubMed:36049848 ]
- Ledoux N: Hepatitis B and Acute Liver Failure. Crit Care Nurs Clin North Am. 2022 Sep;34(3):259-265. doi: 10.1016/j.cnc.2022.04.012. Epub 2022 Jul 20. [PubMed:36049845 ]
- Armstrong PW, Zheng Y, Troughton RW, Lund LH, Zhang J, Lam CSP, Westerhout CM, Blaustein RO, Butler J, Hernandez AF, Roessig L, O'Connor CM, Voors AA, Ezekowitz JA: Sequential Evaluation of NT-proBNP in Heart Failure: Insights Into Clinical Outcomes and Efficacy of Vericiguat. JACC Heart Fail. 2022 Sep;10(9):677-688. doi: 10.1016/j.jchf.2022.04.015. Epub 2022 Jul 6. [PubMed:36049817 ]
- Nevens F, van der Merwe S: Mesenchymal Stem Cell Transplantation in Liver Diseases. Semin Liver Dis. 2022 Aug;42(3):283-292. doi: 10.1055/s-0042-1755328. Epub 2022 Sep 1. [PubMed:36049782 ]
- Budden T, Dimmock JA, Rosenberg M, Beauchamp MR, Fitzpatrick I, Jackson B: MAN v FAT Soccer: Feasibility Study and Preliminary Efficacy of a Sport-Based Weight-Loss Intervention for Overweight and Obese Men in Australia. J Sport Exerc Psychol. 2022 Aug 30;44(5):359-369. doi: 10.1123/jsep.2021-0165. Print 2022 Oct 1. [PubMed:36049750 ]
- Seiler BD, Monsma EV, Newman-Norlund R, Sacko R: Neural Activity During Imagery Supports Three Imagery Abilities as Measured by the Movement Imagery Questionnaire-3. J Sport Exerc Psychol. 2022 Sep 1;44(5):344-358. doi: 10.1123/jsep.2021-0229. Print 2022 Oct 1. [PubMed:36049745 ]
- Tang Y, Song L, Ji X, Huang S, Yu Y, Ye J, Xu W, Hou M: Algal-bacterial consortium mediated system offers effective removal of nitrogen nutrients and antibiotic resistance genes. Bioresour Technol. 2022 Oct;362:127874. doi: 10.1016/j.biortech.2022.127874. Epub 2022 Aug 30. [PubMed:36049708 ]
- Silberman J, Sarlati S, Harris B, Bokhari W, Boushey H, Chesnutt A, Zhu P, Sitts K, Taylor TH, Willey VJ, Fuentes E, LeKrey M, Hou E, Kaur M, Niyonkuru C, Muscioni G, Bianchi MT, Bota DA, Lee RA: A digital approach to asthma self-management in adults: Protocol for a pragmatic randomized controlled trial. Contemp Clin Trials. 2022 Nov;122:106902. doi: 10.1016/j.cct.2022.106902. Epub 2022 Aug 30. [PubMed:36049674 ]
- Bueno AC, More CB, Marrero-Gutierrez J, de Almeida E Silva DC, Leal LF, Montaldi AP, Ramalho FS, Vencio RZN, de Castro M, Antonini SRR: Vitamin D receptor activation is a feasible therapeutic target to impair adrenocortical tumorigenesis. Mol Cell Endocrinol. 2022 Dec 1;558:111757. doi: 10.1016/j.mce.2022.111757. Epub 2022 Aug 29. [PubMed:36049598 ]
- LOTUS database [Link]
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