NP-MRD: Showing NP-Card for Isomurralonginol acetate (NP0139965)

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Record Information

Version

2.0

Created at

2022-06-29 20:18:47 UTC

Updated at

2022-06-29 20:18:47 UTC

NP-MRD ID

NP0139965

Secondary Accession Numbers

None

Natural Product Identification

Common Name

Isomurralonginol acetate

Description

Isomurralonginol acetate belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one). Isomurralonginol acetate is found in Murraya paniculata. Isomurralonginol acetate is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI

     RDKit          3D

 40 41  0  0  0  0  0  0  0  0999 V2000
   -1.0401   -1.9617   -2.0450 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2135   -1.6604   -1.8183 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2728   -2.3857   -2.5636 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5879   -0.5652   -0.9194 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.8453   -0.6765   -0.1493 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2706    0.5141    0.4300 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.4153    0.4291    1.2528 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8797    1.6780    1.8963 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9657   -0.6724    1.3987 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5340   -0.0355   -0.0913 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3928   -0.8670    0.5953 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1033   -2.2484    0.6912 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9941   -3.0830    1.4113 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5177   -0.3441    1.1911 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8358    0.9939    1.1395 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9821    1.8394    0.4587 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2557    3.2051    0.3704 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3916    4.0285   -0.3202 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2836    3.4071   -0.8872 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5024    4.1416   -1.5133 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0406    2.1303   -0.7944 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8683    1.3272   -0.1333 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9219   -1.4752   -1.6310 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2395   -2.8223   -2.7253 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5557   -1.8190   -3.5000 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7846   -3.3149   -2.9742 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1246   -2.7052   -1.9732 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7755    0.3140   -1.7049 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6712   -1.4003    0.7062 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.6644   -1.1765   -0.7316 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.7878    2.5426    1.2267 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3067    1.8634    2.8502 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.9489    1.5116    2.2117 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5627   -4.1039    1.5405 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0626   -2.5988    2.4296 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9746   -3.0471    0.9409 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1738   -1.0578    1.7192 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7075    1.4086    1.6000 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1404    3.5933    0.8451 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5502    5.0930   -0.4300 H   0  0  0  0  0  0  0  0  0  0  0  0
 13 12  1  0
 12 11  1  0
 11 14  2  0
 14 15  1  0
 15 16  2  0
 16 17  1  0
 17 18  2  0
 18 19  1  0
 19 20  2  0
 19 21  1  0
 21 22  1  0
 22 10  2  0
 10  4  1  0
  4  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  7  9  2  0
  4  2  1  0
  2  3  1  0
  2  1  2  3
 10 11  1  0
 22 16  1  0
 13 34  1  0
 13 35  1  0
 13 36  1  0
 14 37  1  0
 15 38  1  0
 17 39  1  0
 18 40  1  0
  4 28  1  6
  5 29  1  0
  5 30  1  0
  8 31  1  0
  8 32  1  0
  8 33  1  0
  3 25  1  0
  3 26  1  0
  3 27  1  0
  1 23  1  0
  1 24  1  0
M  END


  Mrv1533004151519332D          

 22 23  0  0  0  0            999 V2000
    5.8263    1.0164    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2388    1.7309    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.0638    1.7309    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.4763    2.4454    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.3013    2.4454    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.7138    1.7309    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.5388    1.7309    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.9513    1.0164    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.5388    0.3020    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.9513   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.7138    0.3020    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.3013    1.0164    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.4763    1.0164    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0638    0.3020    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2388    0.3020    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.8263   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5888   -1.1270    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.5888    0.3020    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.4763   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.3013   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0638   -1.1270    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
  9 11  1  0  0  0  0
 11 12  1  0  0  0  0
  6 12  1  0  0  0  0
 12 13  2  0  0  0  0
  3 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  2  0  0  0  0
 17 19  1  0  0  0  0
 14 20  1  0  0  0  0
 20 21  2  0  0  0  0
 20 22  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0139965

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC1=CC=C2C=CC(=O)OC2=C1C(COC(C)=O)C(C)=C

> <INCHI_IDENTIFIER>
InChI=1S/C17H18O5/c1-10(2)13(9-21-11(3)18)16-14(20-4)7-5-12-6-8-15(19)22-17(12)16/h5-8,13H,1,9H2,2-4H3

> <INCHI_KEY>
KJRYZFDEVYMOEY-UHFFFAOYSA-N

> <FORMULA>
C17H18O5

> <MOLECULAR_WEIGHT>
302.326

> <EXACT_MASS>
302.11542368

> <JCHEM_ACCEPTOR_COUNT>
3

> <JCHEM_ATOM_COUNT>
40

> <JCHEM_AVERAGE_POLARIZABILITY>
30.84721212527856

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
2-(7-methoxy-2-oxo-2H-chromen-8-yl)-3-methylbut-3-en-1-yl acetate

> <ALOGPS_LOGP>
2.68

> <JCHEM_LOGP>
2.3370399743333334

> <ALOGPS_LOGS>
-4.32

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_BASIC>
-4.839878789204022

> <JCHEM_POLAR_SURFACE_AREA>
61.830000000000005

> <JCHEM_REFRACTIVITY>
82.13290000000002

> <JCHEM_ROTATABLE_BOND_COUNT>
6

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
1.46e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
2-(7-methoxy-2-oxochromen-8-yl)-3-methylbut-3-en-1-yl acetate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 15-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   15-APR-15         0                                  
HETATM    1  C   UNK     0      10.876   1.897   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0      11.646   3.231   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0      13.186   3.231   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      13.956   4.565   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      15.496   4.565   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      16.266   3.231   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      17.806   3.231   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      18.576   1.897   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      17.806   0.564   0.000  0.00  0.00           C+0
HETATM   10  O   UNK     0      18.576  -0.770   0.000  0.00  0.00           O+0
HETATM   11  O   UNK     0      16.266   0.564   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0      15.496   1.897   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      13.956   1.897   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0      13.186   0.564   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0      11.646   0.564   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0      10.876  -0.770   0.000  0.00  0.00           O+0
HETATM   17  C   UNK     0       9.336  -0.770   0.000  0.00  0.00           C+0
HETATM   18  O   UNK     0       8.566  -2.104   0.000  0.00  0.00           O+0
HETATM   19  C   UNK     0       8.566   0.564   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      13.956  -0.770   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      15.496  -0.770   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      13.186  -2.104   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4   13                                                  
CONECT    4    3    5                                                       
CONECT    5    4    6                                                       
CONECT    6    5    7   12                                                  
CONECT    7    6    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8   10   11                                                  
CONECT   10    9                                                            
CONECT   11    9   12                                                       
CONECT   12   11    6   13                                                  
CONECT   13   12    3   14                                                  
CONECT   14   13   15   20                                                  
CONECT   15   14   16                                                       
CONECT   16   15   17                                                       
CONECT   17   16   18   19                                                  
CONECT   18   17                                                            
CONECT   19   17                                                            
CONECT   20   14   21   22                                                  
CONECT   21   20                                                            
CONECT   22   20                                                            
MASTER        0    0    0    0    0    0    0    0   22    0   46    0
END

View in JSmol

Synonyms

Value	Source
Isomurralonginol acetic acid	Generator
2-(7-Methoxy-2-oxo-2H-chromen-8-yl)-3-methylbut-3-en-1-yl acetic acid	Generator

Chemical Formula

C₁₇H₁₈O₅

Average Mass

302.3260 Da

Monoisotopic Mass

302.11542 Da

IUPAC Name

2-(7-methoxy-2-oxo-2H-chromen-8-yl)-3-methylbut-3-en-1-yl acetate

Traditional Name

2-(7-methoxy-2-oxochromen-8-yl)-3-methylbut-3-en-1-yl acetate

CAS Registry Number

Not Available

SMILES

COC1=CC=C2C=CC(=O)OC2=C1C(COC(C)=O)C(C)=C

InChI Identifier

InChI=1S/C17H18O5/c1-10(2)13(9-21-11(3)18)16-14(20-4)7-5-12-6-8-15(19)22-17(12)16/h5-8,13H,1,9H2,2-4H3

InChI Key

KJRYZFDEVYMOEY-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Murraya paniculata	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one).

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Coumarins and derivatives

Sub Class

Not Available

Direct Parent

Coumarins and derivatives

Alternative Parents

Substituents

Coumarin
Benzopyran
1-benzopyran
Anisole
Alkyl aryl ether
Pyranone
Benzenoid
Pyran
Heteroaromatic compound
Carboxylic acid ester
Lactone
Carboxylic acid derivative
Oxacycle
Organoheterocyclic compound
Ether
Monocarboxylic acid or derivatives
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	2.68	ALOGPS
logP	2.34	ChemAxon
logS	-4.3	ALOGPS
pKa (Strongest Basic)	-4.8	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	3	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	61.83 Å²	ChemAxon
Rotatable Bond Count	6	ChemAxon
Refractivity	82.13 m³·mol⁻¹	ChemAxon
Polarizability	30.85 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

13917402

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Not Available

Showing NP-Card for Isomurralonginol acetate (NP0139965)

MOL for NP0139965 (Isomurralonginol acetate)

3D MOL for NP0139965 (Isomurralonginol acetate)

3D SDF for NP0139965 (Isomurralonginol acetate)

3D-SDF for NP0139965 (Isomurralonginol acetate)

PDB for NP0139965 (Isomurralonginol acetate)

3D PDB for NP0139965 (Isomurralonginol acetate)

SMILES for NP0139965 (Isomurralonginol acetate)

INCHI for NP0139965 (Isomurralonginol acetate)

Structure for NP0139965 (Isomurralonginol acetate)

3D Structure for NP0139965 (Isomurralonginol acetate)