NP-MRD: Showing NP-Card for Arginylphenylalanine (NP0136355)

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Record Information

Version

2.0

Created at

2022-05-12 15:12:26 UTC

Updated at

2022-05-12 15:12:26 UTC

NP-MRD ID

NP0136355

Secondary Accession Numbers

None

Natural Product Identification

Common Name

Arginylphenylalanine

Description

Arginylphenylalanine, also known as RF or L-arg-L-phe, belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond. Arginylphenylalanine is a very strong basic compound (based on its pKa). Arginylphenylalanine was first documented in 1983 (PMID: 6137771). It is an incomplete breakdown product of protein digestion or protein catabolism (PMID: 22945436).

Structure

MOL 3D MOL SDF PDB SMILES InChI

     RDKit          3D

 46 46  0  0  0  0  0  0  0  0999 V2000
    5.9952    1.4690   -3.0169 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.1348    0.4651   -2.8201 N   0  0  0  0  0  0  0  0  0  0  0  0
    5.7459   -0.1058   -1.7176 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9932   -1.4841   -1.5630 N   0  0  0  0  0  0  0  0  0  0  0  0
    5.0971    0.6596   -0.7196 N   0  0  0  0  0  0  0  0  0  0  0  0
    4.8130    0.0632    0.5668 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7893   -0.9931    0.4943 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4525   -0.6006   -0.0110 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7407    0.4517    0.7644 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.4926    0.0827    2.1442 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.4087    0.6413    0.1265 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3003    0.9690   -1.0983 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8082    0.4713    0.8333 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1212    0.6497    0.2300 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.8808   -0.6444    0.2214 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2170   -0.5121   -0.3813 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3461   -0.6723   -1.7645 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5932   -0.5641   -2.3109 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.7212   -0.3039   -1.5491 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.5442   -0.1517   -0.1738 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3073   -0.2536    0.4100 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8581    1.7579    0.8491 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3035    2.3838    1.8152 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1115    2.1828    0.4681 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.5676   -1.7947   -0.7438 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.6455   -2.2256   -2.2075 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.8236    1.6453   -0.9041 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.7989   -0.3727    0.9071 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.6119    0.8762    1.2864 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.6405   -1.3900    1.5439 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.1950   -1.8590   -0.0660 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.7789   -1.4743   -0.1180 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.5828   -0.2052   -1.0528 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.2475    1.4372    0.7359 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9077    0.7749    2.7745 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6999   -0.8983    2.3405 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7507    0.2051    1.8344 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9640    0.9245   -0.8537 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2799   -1.4203   -0.3306 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9401   -1.0492    1.2696 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4688   -0.8771   -2.3765 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6818   -0.6898   -3.3836 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.6869   -0.2259   -2.0178 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.3815    0.0507    0.4618 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1789   -0.1360    1.4703 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3184    2.7426   -0.3468 H   0  0  0  0  0  0  0  0  0  0  0  0
 10  9  1  0
  9  8  1  0
  8  7  1  0
  7  6  1  0
  6  5  1  0
  5  3  1  0
  3  4  1  0
  3  2  2  0
  9 11  1  0
 11 12  2  0
 11 13  1  0
 13 14  1  0
 14 15  1  0
 15 16  1  0
 16 17  2  0
 17 18  1  0
 18 19  2  0
 19 20  1  0
 20 21  2  0
 14 22  1  0
 22 24  1  0
 22 23  2  0
 21 16  1  0
 10 35  1  0
 10 36  1  0
  9 34  1  1
  8 32  1  0
  8 33  1  0
  7 30  1  0
  7 31  1  0
  6 28  1  0
  6 29  1  0
  5 27  1  0
  4 25  1  0
  4 26  1  0
  2  1  1  0
 13 37  1  0
 14 38  1  6
 15 39  1  0
 15 40  1  0
 17 41  1  0
 18 42  1  0
 19 43  1  0
 20 44  1  0
 21 45  1  0
 24 46  1  0
M  END


  Mrv1652304062013232D          

 23 23  0  0  0  0            999 V2000
 2500.3657 2501.4380    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2501.0806 2501.0263    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
 2501.0806 2500.2008    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
 2501.8017 2499.8012    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2502.5166 2500.2129    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 2501.8017 2498.9757    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
 2501.0868 2498.5619    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2500.3716 2498.9757    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2499.6567 2498.5619    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2498.9439 2498.9757    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
 2498.2290 2498.5619    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2498.2290 2497.7363    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
 2497.4833 2498.9922    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
 2502.5166 2498.5619    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
 2501.7955 2501.4380    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2502.5104 2501.0263    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 2501.7955 2502.2636    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 2499.6503 2501.0257    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2498.9359 2501.4382    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2498.2213 2501.0256    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2498.2213 2500.2007    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2498.9358 2499.7882    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2499.6503 2500.2007    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  1  0  0  0
  2 15  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  2  0  0  0  0
  6  4  1  1  0  0  0
  6  7  1  0  0  0  0
  6 14  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
 10 11  1  0  0  0  0
 11 12  2  0  0  0  0
 11 13  1  0  0  0  0
 15 16  1  0  0  0  0
 15 17  2  0  0  0  0
 18 19  2  0  0  0  0
 19 20  1  0  0  0  0
 20 21  2  0  0  0  0
 21 22  1  0  0  0  0
 22 23  2  0  0  0  0
 23 18  1  0  0  0  0
  1 18  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0136355

> <DATABASE_NAME>
NP-MRD

> <SMILES>
N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

> <INCHI_IDENTIFIER>
InChI=1S/C15H23N5O3/c16-11(7-4-8-19-15(17)18)13(21)20-12(14(22)23)9-10-5-2-1-3-6-10/h1-3,5-6,11-12H,4,7-9,16H2,(H,20,21)(H,22,23)(H4,17,18,19)/t11-,12-/m0/s1

> <INCHI_KEY>
PQBHGSGQZSOLIR-RYUDHWBXSA-N

> <FORMULA>
C15H23N5O3

> <MOLECULAR_WEIGHT>
321.381

> <EXACT_MASS>
321.180089621

> <JCHEM_ACCEPTOR_COUNT>
7

> <JCHEM_ATOM_COUNT>
46

> <JCHEM_AVERAGE_POLARIZABILITY>
34.232633315114256

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
6

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanoic acid

> <ALOGPS_LOGP>
-3.10

> <JCHEM_LOGP>
-2.0230289106583665

> <ALOGPS_LOGS>
-3.30

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
1

> <JCHEM_PHYSIOLOGICAL_CHARGE>
1

> <JCHEM_PKA>
13.613247365030269

> <JCHEM_PKA_STRONGEST_ACIDIC>
3.700130833820877

> <JCHEM_PKA_STRONGEST_BASIC>
12.038419317717487

> <JCHEM_POLAR_SURFACE_AREA>
154.32

> <JCHEM_REFRACTIVITY>
95.8395

> <JCHEM_ROTATABLE_BOND_COUNT>
9

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
1.62e-01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanoic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 06-APR-20   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   06-APR-20         0                                  
HETATM    1  C   UNK     0    4667.3494669.351   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0    4668.6844668.582   0.000  0.00  0.00           C+0
HETATM    3  N   UNK     0    4668.6844667.041   0.000  0.00  0.00           N+0
HETATM    4  C   UNK     0    4670.0304666.296   0.000  0.00  0.00           C+0
HETATM    5  O   UNK     0    4671.3644667.064   0.000  0.00  0.00           O+0
HETATM    6  C   UNK     0    4670.0304664.755   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0    4668.6954663.982   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0    4667.3604664.755   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0    4666.0264663.982   0.000  0.00  0.00           C+0
HETATM   10  N   UNK     0    4664.6954664.755   0.000  0.00  0.00           N+0
HETATM   11  C   UNK     0    4663.3614663.982   0.000  0.00  0.00           C+0
HETATM   12  N   UNK     0    4663.3614662.441   0.000  0.00  0.00           N+0
HETATM   13  N   UNK     0    4661.9694664.785   0.000  0.00  0.00           N+0
HETATM   14  N   UNK     0    4671.3644663.982   0.000  0.00  0.00           N+0
HETATM   15  C   UNK     0    4670.0184669.351   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0    4671.3534668.582   0.000  0.00  0.00           O+0
HETATM   17  O   UNK     0    4670.0184670.892   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0    4666.0144668.581   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0    4664.6804669.351   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0    4663.3464668.581   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0    4663.3464667.041   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0    4664.6804666.271   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0    4666.0144667.041   0.000  0.00  0.00           C+0
CONECT    1    2   18                                                       
CONECT    2    1    3   15                                                  
CONECT    3    2    4                                                       
CONECT    4    3    5    6                                                  
CONECT    5    4                                                            
CONECT    6    4    7   14                                                  
CONECT    7    6    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8   10                                                       
CONECT   10    9   11                                                       
CONECT   11   10   12   13                                                  
CONECT   12   11                                                            
CONECT   13   11                                                            
CONECT   14    6                                                            
CONECT   15    2   16   17                                                  
CONECT   16   15                                                            
CONECT   17   15                                                            
CONECT   18   19   23    1                                                  
CONECT   19   18   20                                                       
CONECT   20   19   21                                                       
CONECT   21   20   22                                                       
CONECT   22   21   23                                                       
CONECT   23   22   18                                                       
MASTER        0    0    0    0    0    0    0    0   23    0   46    0
END

View in JSmol

Synonyms

Value	Source
Arginyl-phenylalanine	ChEBI
L-Arg-L-phe	ChEBI
RF	ChEBI
Arg-phe	HMDB
Arginine phenylalanine dipeptide	HMDB
Arginine-phenylalanine dipeptide	HMDB
L-Arginyl-L-phenylalanine	HMDB
N-Arginylphenylalanine	HMDB
N-L-Arginyl-3-phenylalanine	HMDB
N-L-Arginyl-L-phenylalanine	HMDB
R-F Dipeptide	HMDB
RF Dipeptide	HMDB
Arginylphenylalanine	ChEBI

Chemical Formula

C₁₅H₂₃N₅O₃

Average Mass

321.3810 Da

Monoisotopic Mass

321.18009 Da

IUPAC Name

(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanoic acid

Traditional Name

(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanoic acid

CAS Registry Number

Not Available

SMILES

N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

InChI Identifier

InChI=1S/C15H23N5O3/c16-11(7-4-8-19-15(17)18)13(21)20-12(14(22)23)9-10-5-2-1-3-6-10/h1-3,5-6,11-12H,4,7-9,16H2,(H,20,21)(H,22,23)(H4,17,18,19)/t11-,12-/m0/s1

InChI Key

PQBHGSGQZSOLIR-RYUDHWBXSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Not Available

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Carboxylic acids and derivatives

Sub Class

Amino acids, peptides, and analogues

Direct Parent

Dipeptides

Alternative Parents

Substituents

Alpha-dipeptide
Phenylalanine or derivatives
N-acyl-alpha amino acid or derivatives
N-acyl-alpha-amino acid
N-acyl-l-alpha-amino acid
Alpha-amino acid amide
3-phenylpropanoic-acid
Alpha-amino acid or derivatives
Amphetamine or derivatives
Monocyclic benzene moiety
N-acyl-amine
Benzenoid
Fatty amide
Fatty acyl
Guanidine
Amino acid or derivatives
Amino acid
Carboxamide group
Secondary carboxylic acid amide
Organic 1,3-dipolar compound
Carboxylic acid
Propargyl-type 1,3-dipolar organic compound
Carboximidamide
Monocarboxylic acid or derivatives
Organopnictogen compound
Amine
Organic oxygen compound
Organic nitrogen compound
Carbonyl group
Hydrocarbon derivative
Primary aliphatic amine
Organic oxide
Primary amine
Organooxygen compound
Organonitrogen compound
Aromatic homomonocyclic compound

Molecular Framework

Aromatic homomonocyclic compounds

External Descriptors

dipeptide (CHEBI:73818 )

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	-3.1	ALOGPS
logP	-2	ChemAxon
logS	-3.3	ALOGPS
pKa (Strongest Acidic)	3.7	ChemAxon
pKa (Strongest Basic)	12.04	ChemAxon
Physiological Charge	1	ChemAxon
Hydrogen Acceptor Count	7	ChemAxon
Hydrogen Donor Count	6	ChemAxon
Polar Surface Area	154.32 Å²	ChemAxon
Rotatable Bond Count	9	ChemAxon
Refractivity	95.84 m³·mol⁻¹	ChemAxon
Polarizability	34.23 Å³	ChemAxon
Number of Rings	1	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

HMDB0028716

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

150964

PDB ID

Not Available

ChEBI ID

73818

Good Scents ID

Not Available

References

General References

Kagebayashi T, Kontani N, Yamada Y, Mizushige T, Arai T, Kino K, Ohinata K: Novel CCK-dependent vasorelaxing dipeptide, Arg-Phe, decreases blood pressure and food intake in rodents. Mol Nutr Food Res. 2012 Sep;56(9):1456-63. doi: 10.1002/mnfr.201200168. Epub 2012 Aug 1. [PubMed:22945436 ]
Dockray GJ, Reeve JR Jr, Shively J, Gayton RJ, Barnard CS: A novel active pentapeptide from chicken brain identified by antibodies to FMRFamide. Nature. 1983 Sep 22-28;305(5932):328-30. doi: 10.1038/305328a0. [PubMed:6137771 ]

Showing NP-Card for Arginylphenylalanine (NP0136355)

MOL for NP0136355 (Arginylphenylalanine)

3D MOL for NP0136355 (Arginylphenylalanine)

3D SDF for NP0136355 (Arginylphenylalanine)

3D-SDF for NP0136355 (Arginylphenylalanine)

PDB for NP0136355 (Arginylphenylalanine)

3D PDB for NP0136355 (Arginylphenylalanine)

SMILES for NP0136355 (Arginylphenylalanine)

INCHI for NP0136355 (Arginylphenylalanine)

Structure for NP0136355 (Arginylphenylalanine)

3D Structure for NP0136355 (Arginylphenylalanine)