NP-MRD: Showing NP-Card for Phosphatidylinositol-3,4,5-trisphosphate (NP0087165)

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Record Information

Version

2.0

Created at

2022-05-11 16:41:57 UTC

Updated at

2022-05-11 16:41:57 UTC

NP-MRD ID

NP0087165

Secondary Accession Numbers

None

Natural Product Identification

Common Name

Phosphatidylinositol-3,4,5-trisphosphate

Description

Phosphatidylinositol-3,4,5-trisphosphate belongs to the class of organic compounds known as inositol phosphates. Inositol phosphates are compounds containing a phosphate group attached to an inositol (or cyclohexanehexol) moiety. The generation of PtdIns(3,4,5)P3 at the plasma membrane upon the activation of class I PI 3-kinases causes these proteins to translocate to the plasma membrane and accordingly affects their activity. Phosphatidylinositol-3,4,5-trisphosphate is an extremely weak basic (essentially neutral) compound (based on its pKa). In humans, phosphatidylinositol-3,4,5-trisphosphate is involved in fc epsilon receptor I signaling in mast cells. This enhances the binding of the GRK to the plasma membrane. The PH domain allows binding between PtdIns(3,4,5)P3 and G-protein coupled receptor kinases (GRKs). Phosphatidylinositol-3,4,5-trisphosphate was first documented in 2003 (PMID: 12917336). Such proteins include Akt/PKB, PDK1, Btk1 and ARNO.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv0541 02231219552D          

 38 38  0  0  1  0            999 V2000
   11.7242   -5.8018    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
   12.5492  -10.0887    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
   10.4867   -9.3742    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
   14.1992   -8.6597    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
   11.3117   -6.5163    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.9617   -9.3742    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.3117   -9.3742    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   13.7867   -7.9452    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.4867   -7.9452    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.9617   -6.5163    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.1367   -5.0873    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.0097   -5.3893    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.8347   -9.6762    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   13.2637  -10.5012    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.4867   -8.5492    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.4867  -10.1992    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   13.4847   -9.0722    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   14.9137   -8.2472    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.4387   -6.2143    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.1367  -10.8031    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.6617   -9.3742    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   14.6117   -9.3742    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.9617   -2.2294    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   14.1992   -2.9438    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.5492   -8.6597    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
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   12.9617   -7.9452    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   11.7242   -7.2307    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   11.3117   -7.9452    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   12.5492   -7.2307    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   12.9617   -5.0873    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   13.3742   -4.3728    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   12.9617   -3.6584    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   13.3742   -2.9438    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
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   14.6117   -5.0873    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  5  1  0  0  0  0
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  4  8  1  0  0  0  0
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 28  5  1  1  0  0  0
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 37 38  2  0  0  0  0
 35 38  1  0  0  0  0
M  END

     RDKit          3D

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M  END


  Mrv0541 02231219552D          

 38 38  0  0  1  0            999 V2000
   11.7242   -5.8018    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
   12.5492  -10.0887    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
   10.4867   -9.3742    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
   14.1992   -8.6597    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
   11.3117   -6.5163    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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   13.7867   -7.9452    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.4867   -7.9452    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.9617   -6.5163    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.1367   -5.0873    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.0097   -5.3893    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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    9.6617   -9.3742    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   14.6117   -9.3742    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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   14.1992   -4.3728    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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   14.1992   -5.8018    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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  3  7  1  0  0  0  0
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 28  5  1  1  0  0  0
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 35 32  1  0  0  0  0
 36 38  1  0  0  0  0
 37 38  2  0  0  0  0
 35 38  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0087165

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(=O)OC(COP(O)(=O)O[C@@H]1[C@H](O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1O)OC(C)=O

> <INCHI_IDENTIFIER>
InChI=1S/C12H24O22P4/c1-4(13)29-6(30-5(2)14)3-28-38(26,27)34-9-7(15)10(31-35(17,18)19)12(33-37(23,24)25)11(8(9)16)32-36(20,21)22/h6-12,15-16H,3H2,1-2H3,(H,26,27)(H2,17,18,19)(H2,20,21,22)(H2,23,24,25)/t7-,8-,9-,10+,11-,12-/m0/s1

> <INCHI_KEY>
RQQIRMLGKSPXSE-UQPICLANSA-N

> <FORMULA>
C12H24O22P4

> <MOLECULAR_WEIGHT>
644.2008

> <EXACT_MASS>
643.9709685

> <JCHEM_ACCEPTOR_COUNT>
15

> <JCHEM_AVERAGE_POLARIZABILITY>
47.5068388936121

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
9

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
{[(1S,2S,3S,4S,5R,6S)-3-({[2,2-bis(acetyloxy)ethoxy](hydroxy)phosphoryl}oxy)-2,4-dihydroxy-5,6-bis(phosphonooxy)cyclohexyl]oxy}phosphonic acid

> <ALOGPS_LOGP>
-0.20

> <JCHEM_LOGP>
-4.070388187666666

> <ALOGPS_LOGS>
-1.65

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
1

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-7

> <JCHEM_PKA>
0.8749172009244854

> <JCHEM_PKA_STRONGEST_ACIDIC>
0.3804049912223664

> <JCHEM_PKA_STRONGEST_BASIC>
-3.689092103968366

> <JCHEM_POLAR_SURFACE_AREA>
349.09999999999997

> <JCHEM_REFRACTIVITY>
109.37409999999996

> <JCHEM_ROTATABLE_BOND_COUNT>
15

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
1.44e+01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
[(1S,2S,3S,4S,5R,6S)-3-{[2,2-bis(acetyloxy)ethoxy(hydroxy)phosphoryl]oxy}-2,4-dihydroxy-5,6-bis(phosphonooxy)cyclohexyl]oxyphosphonic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 23-FEB-12   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   23-FEB-12         0                                  
HETATM    1  P   UNK     0      21.885 -10.830   0.000  0.00  0.00           P+0
HETATM    2  P   UNK     0      23.425 -18.832   0.000  0.00  0.00           P+0
HETATM    3  P   UNK     0      19.575 -17.499   0.000  0.00  0.00           P+0
HETATM    4  P   UNK     0      26.505 -16.165   0.000  0.00  0.00           P+0
HETATM    5  O   UNK     0      21.115 -12.164   0.000  0.00  0.00           O+0
HETATM    6  O   UNK     0      24.195 -17.499   0.000  0.00  0.00           O+0
HETATM    7  O   UNK     0      21.115 -17.499   0.000  0.00  0.00           O+0
HETATM    8  O   UNK     0      25.735 -14.831   0.000  0.00  0.00           O+0
HETATM    9  O   UNK     0      19.575 -14.831   0.000  0.00  0.00           O+0
HETATM   10  O   UNK     0      24.195 -12.164   0.000  0.00  0.00           O+0
HETATM   11  O   UNK     0      22.655  -9.496   0.000  0.00  0.00           O+0
HETATM   12  O   UNK     0      20.551 -10.060   0.000  0.00  0.00           O+0
HETATM   13  O   UNK     0      22.091 -18.062   0.000  0.00  0.00           O+0
HETATM   14  O   UNK     0      24.759 -19.602   0.000  0.00  0.00           O+0
HETATM   15  O   UNK     0      19.575 -15.959   0.000  0.00  0.00           O+0
HETATM   16  O   UNK     0      19.575 -19.039   0.000  0.00  0.00           O+0
HETATM   17  O   UNK     0      25.171 -16.935   0.000  0.00  0.00           O+0
HETATM   18  O   UNK     0      27.839 -15.395   0.000  0.00  0.00           O+0
HETATM   19  O   UNK     0      23.219 -11.600   0.000  0.00  0.00           O+0
HETATM   20  O   UNK     0      22.655 -20.166   0.000  0.00  0.00           O+0
HETATM   21  O   UNK     0      18.035 -17.499   0.000  0.00  0.00           O+0
HETATM   22  O   UNK     0      27.275 -17.499   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0      24.195  -4.162   0.000  0.00  0.00           C+0
HETATM   24  O   UNK     0      26.505  -5.495   0.000  0.00  0.00           O+0
HETATM   25  C   UNK     0      23.425 -16.165   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0      21.885 -16.165   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0      24.195 -14.831   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0      21.885 -13.497   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0      21.115 -14.831   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0      23.425 -13.497   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0      24.195  -9.496   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0      24.965  -8.163   0.000  0.00  0.00           C+0
HETATM   33  O   UNK     0      24.195  -6.829   0.000  0.00  0.00           O+0
HETATM   34  C   UNK     0      24.965  -5.495   0.000  0.00  0.00           C+0
HETATM   35  O   UNK     0      26.505  -8.163   0.000  0.00  0.00           O+0
HETATM   36  C   UNK     0      28.815  -9.496   0.000  0.00  0.00           C+0
HETATM   37  O   UNK     0      26.505 -10.830   0.000  0.00  0.00           O+0
HETATM   38  C   UNK     0      27.275  -9.496   0.000  0.00  0.00           C+0
CONECT    1    5   11   12   19                                             
CONECT    2    6   13   14   20                                             
CONECT    3    7   15   16   21                                             
CONECT    4    8   17   18   22                                             
CONECT    5    1   28                                                       
CONECT    6    2   25                                                       
CONECT    7    3   26                                                       
CONECT    8    4   27                                                       
CONECT    9   29                                                            
CONECT   10   30                                                            
CONECT   11    1   31                                                       
CONECT   12    1                                                            
CONECT   13    2                                                            
CONECT   14    2                                                            
CONECT   15    3                                                            
CONECT   16    3                                                            
CONECT   17    4                                                            
CONECT   18    4                                                            
CONECT   19    1                                                            
CONECT   20    2                                                            
CONECT   21    3                                                            
CONECT   22    4                                                            
CONECT   23   34                                                            
CONECT   24   34                                                            
CONECT   25    6   26   27                                                  
CONECT   26    7   25   29                                                  
CONECT   27    8   25   30                                                  
CONECT   28    5   29   30                                                  
CONECT   29    9   26   28                                                  
CONECT   30   10   27   28                                                  
CONECT   31   11   32                                                       
CONECT   32   31   33   35                                                  
CONECT   33   32   34                                                       
CONECT   34   23   24   33                                                  
CONECT   35   32   38                                                       
CONECT   36   38                                                            
CONECT   37   38                                                            
CONECT   38   36   37   35                                                  
MASTER        0    0    0    0    0    0    0    0   38    0   76    0
END

View in JSmol

Synonyms

Value	Source
Phosphatidylinositol-3,4,5-trisphosphoric acid	Generator
1,2-Diacyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-bisphosphate)	HMDB
1-Phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate	HMDB

Chemical Formula

C₁₂H₂₄O₂₂P₄

Average Mass

644.2008 Da

Monoisotopic Mass

643.97097 Da

IUPAC Name

{[(1S,2S,3S,4S,5R,6S)-3-({[2,2-bis(acetyloxy)ethoxy](hydroxy)phosphoryl}oxy)-2,4-dihydroxy-5,6-bis(phosphonooxy)cyclohexyl]oxy}phosphonic acid

Traditional Name

[(1S,2S,3S,4S,5R,6S)-3-{[2,2-bis(acetyloxy)ethoxy(hydroxy)phosphoryl]oxy}-2,4-dihydroxy-5,6-bis(phosphonooxy)cyclohexyl]oxyphosphonic acid

CAS Registry Number

Not Available

SMILES

CC(=O)OC(COP(O)(=O)O[C@@H]1[C@H](O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1O)OC(C)=O

InChI Identifier

InChI=1S/C12H24O22P4/c1-4(13)29-6(30-5(2)14)3-28-38(26,27)34-9-7(15)10(31-35(17,18)19)12(33-37(23,24)25)11(8(9)16)32-36(20,21)22/h6-12,15-16H,3H2,1-2H3,(H,26,27)(H2,17,18,19)(H2,20,21,22)(H2,23,24,25)/t7-,8-,9-,10+,11-,12-/m0/s1

InChI Key

RQQIRMLGKSPXSE-UQPICLANSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Anas platyrhynchos	FooDB	FooDB
Anatidae	FooDB	FooDB
Anser anser	FooDB	FooDB
Bison bison	FooDB	FooDB
Bos taurus	FooDB	FooDB
Bos taurus X Bison bison	FooDB	FooDB
Bubalus bubalis	FooDB	FooDB
Capra aegagrus hircus	FooDB	FooDB
Cervidae	FooDB	FooDB
Cervus canadensis	FooDB	FooDB
Columba	FooDB	FooDB
Columbidae	FooDB	FooDB
Dromaius novaehollandiae	FooDB	FooDB
Equus caballus	FooDB	FooDB
Gallus gallus	FooDB	FooDB
Lagopus muta	FooDB	FooDB
Leporidae	FooDB	FooDB
Lepus timidus	FooDB	FooDB
Melanitta fusca	FooDB	FooDB
Meleagris gallopavo	FooDB	FooDB
Numida meleagris	FooDB	FooDB
Odocoileus	FooDB	FooDB
Oryctolagus	FooDB	FooDB
Ovis aries	FooDB	FooDB
Phasianidae	FooDB	FooDB
Phasianus colchicus	FooDB	FooDB
Struthio camelus	FooDB	FooDB
Sus scrofa	FooDB	FooDB
Sus scrofa domestica	FooDB	FooDB

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as inositol phosphates. Inositol phosphates are compounds containing a phosphate group attached to an inositol (or cyclohexanehexol) moiety.

Kingdom

Organic compounds

Super Class

Organic oxygen compounds

Class

Organooxygen compounds

Sub Class

Alcohols and polyols

Direct Parent

Inositol phosphates

Alternative Parents

Substituents

Inositol phosphate
Cyclohexanol
Acylal
Dialkyl phosphate
Monoalkyl phosphate
Dicarboxylic acid or derivatives
Organic phosphoric acid derivative
Phosphoric acid ester
Alkyl phosphate
Carboxylic acid ester
Secondary alcohol
Acetal
Carboxylic acid derivative
Hydrocarbon derivative
Organic oxide
Carbonyl group
Aliphatic homomonocyclic compound

Molecular Framework

Aliphatic homomonocyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	-0.2	ALOGPS
logP	-4.1	ChemAxon
logS	-1.6	ALOGPS
pKa (Strongest Acidic)	0.38	ChemAxon
pKa (Strongest Basic)	-3.7	ChemAxon
Physiological Charge	-7	ChemAxon
Hydrogen Acceptor Count	15	ChemAxon
Hydrogen Donor Count	9	ChemAxon
Polar Surface Area	349.1 Å²	ChemAxon
Rotatable Bond Count	15	ChemAxon
Refractivity	109.37 m³·mol⁻¹	ChemAxon
Polarizability	47.51 Å³	ChemAxon
Number of Rings	1	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

HMDB0004249

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

FDB023351

KNApSAcK ID

Not Available

Chemspider ID

34980938

KEGG Compound ID

C05981

BioCyc ID

PHOSPHATIDYL-INOSITOL-345-TRISPHOSPHAT

BiGG ID

47125

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

Not Available

PDB ID

Not Available

ChEBI ID

16618

Good Scents ID

Not Available

References

General References

Radu A, Neubauer V, Akagi T, Hanafusa H, Georgescu MM: PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1. Mol Cell Biol. 2003 Sep;23(17):6139-49. doi: 10.1128/MCB.23.17.6139-6149.2003. [PubMed:12917336 ]

Showing NP-Card for Phosphatidylinositol-3,4,5-trisphosphate (NP0087165)

MOL for NP0087165 (Phosphatidylinositol-3,4,5-trisphosphate)

3D MOL for NP0087165 (Phosphatidylinositol-3,4,5-trisphosphate)

3D SDF for NP0087165 (Phosphatidylinositol-3,4,5-trisphosphate)

3D-SDF for NP0087165 (Phosphatidylinositol-3,4,5-trisphosphate)

PDB for NP0087165 (Phosphatidylinositol-3,4,5-trisphosphate)

3D PDB for NP0087165 (Phosphatidylinositol-3,4,5-trisphosphate)

SMILES for NP0087165 (Phosphatidylinositol-3,4,5-trisphosphate)

INCHI for NP0087165 (Phosphatidylinositol-3,4,5-trisphosphate)

Structure for NP0087165 (Phosphatidylinositol-3,4,5-trisphosphate)

3D Structure for NP0087165 (Phosphatidylinositol-3,4,5-trisphosphate)