NP-MRD: Showing NP-Card for (+)-Erythravine (NP0075936)

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Record Information

Version

2.0

Created at

2022-04-28 21:08:26 UTC

Updated at

2022-04-28 21:08:26 UTC

NP-MRD ID

NP0075936

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(+)-Erythravine

Description

Erythravine belongs to the class of organic compounds known as erythrinanes. These are erythrina alkaloids possessing either a 6-5-6-6-membered indoloisoquinoline core or a derivative thereof. (+)-Erythravine is found in Erythrina cochleata, Erythrina folkersii, Erythrina lysistemon, Erythrina mulungu and Erythrina verna. (+)-Erythravine was first documented in 2013 (PMID: 24349349). Based on a literature review a small amount of articles have been published on Erythravine (PMID: 27076115) (PMID: 33791806) (PMID: 32735983) (PMID: 31751584).

Structure

MOL 3D MOL SDF PDB SMILES InChI

     RDKit          3D

 43 46  0  0  0  0  0  0  0  0999 V2000
    4.1851   -3.0646    0.0826 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6727   -1.8974    0.6538 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.4852   -1.2887    0.3002 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6743   -1.8116   -0.6921 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5235   -1.1506   -0.9771 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1525   -0.0067   -0.3204 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9618    0.5348    0.6828 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1374   -0.1295    0.9817 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9684    0.3817    1.9772 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.5992    1.5520    2.6523 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1412    0.6464   -0.6475 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.1582    2.0433   -0.0506 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6221    2.1592    1.3394 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.8843    2.8472    1.3637 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8737    0.9348    2.1140 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2275   -0.1755    1.4529 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3161   -0.0260   -0.0044 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2401   -0.3079   -0.8965 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8181    0.1421   -2.2345 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4646    0.6112   -2.0226 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6467   -0.2723   -2.8428 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4028   -1.5834   -2.0883 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0097   -3.9742    0.6945 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.8895   -3.2309   -0.9660 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3078   -2.9453    0.0635 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9338   -2.7141   -1.2310 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7325    1.4368    1.2172 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.5612    2.4179    1.9322 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3357    1.7602    3.4698 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6083    1.4389    3.1748 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1671    2.5368   -0.2420 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8588    2.6223   -0.7225 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9866    2.8290    1.9726 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1718    2.9987    2.2842 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7814    0.9131    3.1652 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4695   -1.1197    1.9123 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1730   -0.8163   -0.6447 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4591    1.0219   -2.5475 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9062   -0.6499   -3.0027 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.3321    0.1622   -3.0855 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1635   -0.5367   -3.7776 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1729   -2.2322   -2.7558 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3112   -2.0567   -1.7348 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  2  0
  4  5  1  0
  5  6  2  0
  6  7  1  0
  7  8  2  0
  8  9  1  0
  9 10  1  0
  6 11  1  0
 11 12  1  1
 12 13  1  0
 13 14  1  0
 13 15  1  0
 15 16  2  0
 16 17  1  0
 17 18  2  0
 18 19  1  0
 19 20  1  0
 20 21  1  0
 21 22  1  0
  8  3  1  0
 17 11  1  0
 22  5  1  0
 20 11  1  0
  1 23  1  0
  1 24  1  0
  1 25  1  0
  4 26  1  0
  7 27  1  0
 10 28  1  0
 10 29  1  0
 10 30  1  0
 12 31  1  0
 12 32  1  0
 13 33  1  1
 14 34  1  0
 15 35  1  0
 16 36  1  0
 18 37  1  0
 19 38  1  0
 19 39  1  0
 21 40  1  0
 21 41  1  0
 22 42  1  0
 22 43  1  0
M  END


  Mrv1652304282223082D          

 22 25  0  0  1  0            999 V2000
    2.3589   -0.5615    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.1248    0.1072    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2677    0.3610    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.7350   -0.2691    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0288    0.0428    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0318    0.8656    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8330    1.0622    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.2230    1.7892    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0476    1.8150    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4822    1.1137    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0922    0.3867    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5269   -0.3145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3515   -0.2887    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7414    0.4383    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3068    1.1395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5660    0.4640    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.9560    1.1910    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7861   -0.9900    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.6107   -0.9642    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0143   -1.0453    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8263   -1.1916    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1708   -0.7078    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  2  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  3  7  1  1  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
 10 11  2  0  0  0  0
  3 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  2  0  0  0  0
 13 14  1  0  0  0  0
 14 15  2  0  0  0  0
 10 15  1  0  0  0  0
 14 16  1  0  0  0  0
 16 17  1  0  0  0  0
 13 18  1  0  0  0  0
 18 19  1  0  0  0  0
  4 20  1  0  0  0  0
 20 21  2  0  0  0  0
  1 21  1  0  0  0  0
  1 22  1  1  0  0  0
M  END
> <DATABASE_ID>
NP0075936

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC1=CC2=C(C=C1OC)[C@]13C[C@@H](O)C=CC1=CCN3CC2

> <INCHI_IDENTIFIER>
InChI=1S/C18H21NO3/c1-21-16-9-12-5-7-19-8-6-13-3-4-14(20)11-18(13,19)15(12)10-17(16)22-2/h3-4,6,9-10,14,20H,5,7-8,11H2,1-2H3/t14-,18-/m0/s1

> <INCHI_KEY>
JEBFJSHKHYDVNP-KSSFIOAISA-N

> <FORMULA>
C18H21NO3

> <MOLECULAR_WEIGHT>
299.37

> <EXACT_MASS>
299.15214354

> <JCHEM_ACCEPTOR_COUNT>
4

> <JCHEM_ATOM_COUNT>
43

> <JCHEM_AVERAGE_POLARIZABILITY>
32.46222919538664

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
(1S,16R)-4,5-dimethoxy-10-azatetracyclo[8.7.0.0^{1,13}.0^{2,7}]heptadeca-2(7),3,5,12,14-pentaen-16-ol

> <ALOGPS_LOGP>
1.70

> <JCHEM_LOGP>
1.416422725666667

> <ALOGPS_LOGS>
-2.50

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
1

> <JCHEM_PKA_STRONGEST_ACIDIC>
14.798482385803158

> <JCHEM_PKA_STRONGEST_BASIC>
8.643330607040603

> <JCHEM_POLAR_SURFACE_AREA>
41.93000000000001

> <JCHEM_REFRACTIVITY>
87.688

> <JCHEM_ROTATABLE_BOND_COUNT>
2

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
9.36e-01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(1S,16R)-4,5-dimethoxy-10-azatetracyclo[8.7.0.0^{1,13}.0^{2,7}]heptadeca-2(7),3,5,12,14-pentaen-16-ol

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 28-APR-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   28-APR-22         0                                  
HETATM    1  C   UNK     0       4.403  -1.048   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       3.966   0.200   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       2.366   0.674   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       1.372  -0.502   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -0.054   0.080   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       0.059   1.616   0.000  0.00  0.00           C+0
HETATM    7  N   UNK     0       1.555   1.983   0.000  0.00  0.00           N+0
HETATM    8  C   UNK     0       2.283   3.340   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       3.822   3.388   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       4.634   2.079   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       3.906   0.722   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       4.717  -0.587   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       6.256  -0.539   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       6.984   0.818   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       6.173   2.127   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0       8.523   0.866   0.000  0.00  0.00           O+0
HETATM   17  C   UNK     0       9.251   2.223   0.000  0.00  0.00           C+0
HETATM   18  O   UNK     0       7.067  -1.848   0.000  0.00  0.00           O+0
HETATM   19  C   UNK     0       8.607  -1.800   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       1.893  -1.951   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       3.409  -2.224   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0       5.919  -1.321   0.000  0.00  0.00           O+0
CONECT    1    2   21   22                                                  
CONECT    2    1    3                                                       
CONECT    3    2    4    7   11                                             
CONECT    4    3    5   20                                                  
CONECT    5    4    6                                                       
CONECT    6    5    7                                                       
CONECT    7    6    3    8                                                  
CONECT    8    7    9                                                       
CONECT    9    8   10                                                       
CONECT   10    9   11   15                                                  
CONECT   11   10    3   12                                                  
CONECT   12   11   13                                                       
CONECT   13   12   14   18                                                  
CONECT   14   13   15   16                                                  
CONECT   15   14   10                                                       
CONECT   16   14   17                                                       
CONECT   17   16                                                            
CONECT   18   13   19                                                       
CONECT   19   18                                                            
CONECT   20    4   21                                                       
CONECT   21   20    1                                                       
CONECT   22    1                                                            
MASTER        0    0    0    0    0    0    0    0   22    0   50    0
END

View in JSmol

Synonyms

Value	Source
(+)-Erythravine	MeSH

Chemical Formula

C₁₈H₂₁NO₃

Average Mass

299.3700 Da

Monoisotopic Mass

299.15214 Da

IUPAC Name

(1S,16R)-4,5-dimethoxy-10-azatetracyclo[8.7.0.0^{1,13}.0^{2,7}]heptadeca-2(7),3,5,12,14-pentaen-16-ol

Traditional Name

(1S,16R)-4,5-dimethoxy-10-azatetracyclo[8.7.0.0^{1,13}.0^{2,7}]heptadeca-2(7),3,5,12,14-pentaen-16-ol

CAS Registry Number

Not Available

SMILES

COC1=CC2=C(C=C1OC)[C@]13C[C@@H](O)C=CC1=CCN3CC2

InChI Identifier

InChI=1S/C18H21NO3/c1-21-16-9-12-5-7-19-8-6-13-3-4-14(20)11-18(13,19)15(12)10-17(16)22-2/h3-4,6,9-10,14,20H,5,7-8,11H2,1-2H3/t14-,18-/m0/s1

InChI Key

JEBFJSHKHYDVNP-KSSFIOAISA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Erythrina cochleata	LOTUS Database	35616633
Erythrina folkersii	LOTUS Database	35616633
Erythrina lysistemon	LOTUS Database	35616633
Erythrina mulungu	Plant	KNApSAcK
Erythrina verna	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as erythrinanes. These are erythrina alkaloids possessing either a 6-5-6-6-membered indoloisoquinoline core or a derivative thereof.

Kingdom

Organic compounds

Super Class

Alkaloids and derivatives

Class

Erythrina alkaloids

Sub Class

Erythrinanes

Direct Parent

Erythrinanes

Alternative Parents

Substituents

Erythrinane skeleton
Tetrahydroisoquinoline
Indole or derivatives
Anisole
Phenol ether
Alkyl aryl ether
Aralkylamine
Benzenoid
Pyrroline
Tertiary amine
Secondary alcohol
Tertiary aliphatic amine
Organoheterocyclic compound
Azacycle
Ether
Alcohol
Organooxygen compound
Organonitrogen compound
Hydrocarbon derivative
Organic oxygen compound
Amine
Organic nitrogen compound
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	1.7	ALOGPS
logP	1.42	ChemAxon
logS	-2.5	ALOGPS
pKa (Strongest Acidic)	14.8	ChemAxon
pKa (Strongest Basic)	8.64	ChemAxon
Physiological Charge	1	ChemAxon
Hydrogen Acceptor Count	4	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	41.93 Å²	ChemAxon
Rotatable Bond Count	2	ChemAxon
Refractivity	87.69 m³·mol⁻¹	ChemAxon
Polarizability	32.46 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

C00038065

Chemspider ID

9406901

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Erythravine

METLIN ID

Not Available

PubChem Compound

11231853

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Andreev IA, Ratmanova NK, Novoselov AM, Belov DS, Seregina IF, Kurkin AV: Oxidative Dearomatization of 4,5,6,7-Tetrahydro-1H-indoles Obtained by Metal- and Solvent-Free Thermal 5-endo-dig Cyclization: The Route to Erythrina and Lycorine Alkaloids. Chemistry. 2016 May 17;22(21):7262-7. doi: 10.1002/chem.201600273. Epub 2016 Apr 14. [PubMed:27076115 ]
Dos Reis SL, Gelfuso EA, Fachin AL, Pereira AMS, Beleboni RO: Pharmacological characterisation of anticonvulsant effects elicited by erythrartine. J Pharm Pharmacol. 2021 Mar 1;73(1):93-97. doi: 10.1093/jpp/rgaa024. [PubMed:33791806 ]
Gelfuso EA, Reis SL, Aguiar DSR, Faggion SA, Gomes FMM, Galan DT, Peigneur S, Pereira AMS, Mortari MR, Cunha AOS, Tytgat J, Beleboni RO: New insights in the mode of action of (+)-erythravine and (+)-11alpha-hydroxy-erythravine alkaloids. Eur J Pharmacol. 2020 Oct 15;885:173390. doi: 10.1016/j.ejphar.2020.173390. Epub 2020 Jul 29. [PubMed:32735983 ]
Gelfuso EA, Reis SL, Pereira AMS, Aguiar DSR, Beleboni RO: Neuroprotective effects and improvement of learning and memory elicited by erythravine and 11alpha-hydroxy-erythravine against the pilocarpine model of epilepsy. Life Sci. 2020 Jan 1;240:117072. doi: 10.1016/j.lfs.2019.117072. Epub 2019 Nov 18. [PubMed:31751584 ]
Setti-Perdigao P, Serrano MA, Flausino OA Jr, Bolzani VS, Guimaraes MZ, Castro NG: Erythrina mulungu alkaloids are potent inhibitors of neuronal nicotinic receptor currents in mammalian cells. PLoS One. 2013 Dec 13;8(12):e82726. doi: 10.1371/journal.pone.0082726. eCollection 2013. [PubMed:24349349 ]

Showing NP-Card for (+)-Erythravine (NP0075936)

MOL for NP0075936 ((+)-Erythravine)

3D MOL for NP0075936 ((+)-Erythravine)

3D SDF for NP0075936 ((+)-Erythravine)

3D-SDF for NP0075936 ((+)-Erythravine)

PDB for NP0075936 ((+)-Erythravine)

3D PDB for NP0075936 ((+)-Erythravine)

SMILES for NP0075936 ((+)-Erythravine)

INCHI for NP0075936 ((+)-Erythravine)

Structure for NP0075936 ((+)-Erythravine)

3D Structure for NP0075936 ((+)-Erythravine)