NP-MRD: Showing NP-Card for (-)-Hoodigoside D (NP0074436)

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Record Information

Version

2.0

Created at

2022-04-28 19:41:04 UTC

Updated at

2022-04-28 19:41:04 UTC

NP-MRD ID

NP0074436

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(-)-Hoodigoside D

Description

(1S,2R,5S,10R,11S,14S,15S,16R)-14-acetyl-5-{[(2R,4S,5R,6R)-5-{[(2S,4R,5R,6R)-5-{[(2S,3R,4R,5R,6R)-5-{[(2S,3R,4S,5R,6R)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-3-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-11-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]Heptadec-7-en-16-yl (2E)-2-methylbut-2-enoate belongs to the class of organic compounds known as steroidal glycosides. These are sterol lipids containing a carbohydrate moiety glycosidically linked to the steroid skeleton. (-)-Hoodigoside D is found in Hoodia gordonii . Based on a literature review very few articles have been published on (1S,2R,5S,10R,11S,14S,15S,16R)-14-acetyl-5-{[(2R,4S,5R,6R)-5-{[(2S,4R,5R,6R)-5-{[(2S,3R,4R,5R,6R)-5-{[(2S,3R,4S,5R,6R)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-3-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-11-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]Heptadec-7-en-16-yl (2E)-2-methylbut-2-enoate.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652304282221412D          

 73 80  0  0  1  0            999 V2000
    6.1708   -0.2182    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4511    0.5577    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.9193    1.1884    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.1072    1.0432    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5754    1.6739    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7633    1.5287    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4830    0.7528    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.0148    0.1221    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.8269    0.2673    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.3587   -0.3634    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5466   -0.5086    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7345   -0.6539    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9224   -0.7991    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.3905   -0.1684    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.6708    0.6076    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.0195    1.1139    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3367    0.6509    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5660   -0.1416    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.0596   -0.7929    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3705   -1.5571    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.2424   -0.6800    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8685    1.4085    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.0307   -0.9107    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6421   -1.5750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.1739   -2.2057    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9860   -2.0605    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8936   -2.9816    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4254   -3.6123    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1451   -4.3883    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0815   -3.1268    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.2632    0.7029    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.5435    1.4789    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    8.3557    1.6241    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.6360    2.4000    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    8.1041    3.0307    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    7.2920    2.8855    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    7.0117    2.1096    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.7602    3.5162    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.0405    4.2921    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.3844    3.8066    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.1966    3.9518    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    9.4769    4.7278    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.2890    4.8730    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   10.8208    4.2423    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   10.5405    3.4663    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    9.7284    3.3211    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.0723    2.8356    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.6329    4.3875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.1647    3.7568    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   11.8844    2.9809    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.4163    2.3501    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   13.2284    2.4954    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   13.5087    3.2713    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   12.9769    3.9020    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   13.2572    4.6779    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   14.3208    3.4165    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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   13.7602    1.8647    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   13.4799    1.0887    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   14.0117    0.4580    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   13.7314   -0.3179    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   12.9193   -0.4631    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   12.3875    0.1676    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   12.6678    0.9435    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.5754    0.0224    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   12.6390   -1.2390    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   14.2632   -0.9486    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   13.9829   -1.7245    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   14.8238    0.6032    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.1360    1.5742    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.5693    5.6489    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.3814    5.7941    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.4481    2.5452    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  2  0  0  0  0
  5  6  1  0  0  0  0
  7  6  1  6  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  4  9  1  0  0  0  0
  9 10  1  0  0  0  0
  1 10  1  0  0  0  0
  9 11  1  1  0  0  0
  8 12  1  1  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
  7 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 14 18  1  0  0  0  0
 18 19  1  1  0  0  0
 19 20  2  0  0  0  0
 19 21  1  0  0  0  0
 15 22  1  1  0  0  0
 14 23  1  1  0  0  0
 13 24  1  1  0  0  0
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 25 26  2  0  0  0  0
 25 27  1  0  0  0  0
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 28 29  1  0  0  0  0
 27 30  1  0  0  0  0
  2 31  1  1  0  0  0
 32 31  1  1  0  0  0
 32 33  1  0  0  0  0
 33 34  1  0  0  0  0
 34 35  1  0  0  0  0
 35 36  1  0  0  0  0
 36 37  1  0  0  0  0
 32 37  1  0  0  0  0
 36 38  1  6  0  0  0
 38 39  1  0  0  0  0
 35 40  1  6  0  0  0
 41 40  1  1  0  0  0
 41 42  1  0  0  0  0
 42 43  1  0  0  0  0
 43 44  1  0  0  0  0
 44 45  1  0  0  0  0
 45 46  1  0  0  0  0
 41 46  1  0  0  0  0
 45 47  1  1  0  0  0
 44 48  1  6  0  0  0
 49 48  1  1  0  0  0
 49 50  1  0  0  0  0
 50 51  1  0  0  0  0
 51 52  1  0  0  0  0
 52 53  1  0  0  0  0
 53 54  1  0  0  0  0
 49 54  1  0  0  0  0
 54 55  1  6  0  0  0
 53 56  1  1  0  0  0
 56 57  1  0  0  0  0
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 59 58  1  1  0  0  0
 59 60  1  0  0  0  0
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 63 64  1  0  0  0  0
 59 64  1  0  0  0  0
 63 65  1  1  0  0  0
 62 66  1  6  0  0  0
 61 67  1  1  0  0  0
 67 68  1  0  0  0  0
 60 69  1  6  0  0  0
 51 70  1  1  0  0  0
 43 71  1  1  0  0  0
 71 72  1  0  0  0  0
 34 73  1  1  0  0  0
M  END

     RDKit          3D

159166  0  0  0  0  0  0  0  0999 V2000
   14.2446    2.7240   -4.1792 C   0  0  0  0  0  0  0  0  0  0  0  0
   13.2499    2.1266   -3.2246 C   0  0  0  0  0  0  0  0  0  0  0  0
   12.7679    0.9097   -3.3405 C   0  0  0  0  0  0  0  0  0  0  0  0
   13.2268    0.0671   -4.4707 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.8036    0.3424   -2.4078 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.3537   -0.8322   -2.5477 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.3042    1.0323   -1.3007 O   0  0  0  0  0  0  0  0  0  0  0  0
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   -0.9890   -1.2539   -0.2061 C   0  0  2  0  0  0  0  0  0  0  0  0
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    6.1110    0.3571   -0.8492 C   0  0  0  0  0  0  0  0  0  0  0  0
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M  END


  Mrv1652304282221412D          

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  4  5  2  0  0  0  0
  5  6  1  0  0  0  0
  7  6  1  6  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  4  9  1  0  0  0  0
  9 10  1  0  0  0  0
  1 10  1  0  0  0  0
  9 11  1  1  0  0  0
  8 12  1  1  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
  7 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 14 18  1  0  0  0  0
 18 19  1  1  0  0  0
 19 20  2  0  0  0  0
 19 21  1  0  0  0  0
 15 22  1  1  0  0  0
 14 23  1  1  0  0  0
 13 24  1  1  0  0  0
 24 25  1  0  0  0  0
 25 26  2  0  0  0  0
 25 27  1  0  0  0  0
 27 28  2  0  0  0  0
 28 29  1  0  0  0  0
 27 30  1  0  0  0  0
  2 31  1  1  0  0  0
 32 31  1  1  0  0  0
 32 33  1  0  0  0  0
 33 34  1  0  0  0  0
 34 35  1  0  0  0  0
 35 36  1  0  0  0  0
 36 37  1  0  0  0  0
 32 37  1  0  0  0  0
 36 38  1  6  0  0  0
 38 39  1  0  0  0  0
 35 40  1  6  0  0  0
 41 40  1  1  0  0  0
 41 42  1  0  0  0  0
 42 43  1  0  0  0  0
 43 44  1  0  0  0  0
 44 45  1  0  0  0  0
 45 46  1  0  0  0  0
 41 46  1  0  0  0  0
 45 47  1  1  0  0  0
 44 48  1  6  0  0  0
 49 48  1  1  0  0  0
 49 50  1  0  0  0  0
 50 51  1  0  0  0  0
 51 52  1  0  0  0  0
 52 53  1  0  0  0  0
 53 54  1  0  0  0  0
 49 54  1  0  0  0  0
 54 55  1  6  0  0  0
 53 56  1  1  0  0  0
 56 57  1  0  0  0  0
 52 58  1  6  0  0  0
 59 58  1  1  0  0  0
 59 60  1  0  0  0  0
 60 61  1  0  0  0  0
 61 62  1  0  0  0  0
 62 63  1  0  0  0  0
 63 64  1  0  0  0  0
 59 64  1  0  0  0  0
 63 65  1  1  0  0  0
 62 66  1  6  0  0  0
 61 67  1  1  0  0  0
 67 68  1  0  0  0  0
 60 69  1  6  0  0  0
 51 70  1  1  0  0  0
 43 71  1  1  0  0  0
 71 72  1  0  0  0  0
 34 73  1  1  0  0  0
M  END
> <DATABASE_ID>
NP0074436

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CO[C@H]1C[C@H](O[C@H]2CC[C@]3(C)[C@H]4C[C@@H](OC(=O)C(\C)=C\C)[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC=C3C2)C(C)=O)O[C@H](C)[C@H]1O[C@H]1C[C@@H](OC)[C@H](O[C@@H]2O[C@H](C)[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](OC)[C@H]3O)[C@H](OC)[C@H]2O)[C@@H](C)O1

> <INCHI_IDENTIFIER>
InChI=1S/C54H86O19/c1-14-25(2)49(59)70-38-22-35-34(54(60)20-18-33(26(3)55)53(38,54)9)16-15-31-21-32(17-19-52(31,35)8)69-39-23-36(61-10)44(28(5)65-39)71-40-24-37(62-11)45(29(6)66-40)72-51-43(58)48(64-13)46(30(7)68-51)73-50-42(57)47(63-12)41(56)27(4)67-50/h14-15,27-30,32-48,50-51,56-58,60H,16-24H2,1-13H3/b25-14+/t27-,28-,29-,30-,32+,33-,34-,35+,36+,37-,38-,39+,40+,41-,42-,43-,44-,45-,46-,47+,48-,50+,51+,52+,53+,54+/m1/s1

> <INCHI_KEY>
NGOPWLMMSZURID-FCVVVZLZSA-N

> <FORMULA>
C54H86O19

> <MOLECULAR_WEIGHT>
1039.263

> <EXACT_MASS>
1038.576330549

> <JCHEM_ACCEPTOR_COUNT>
18

> <JCHEM_ATOM_COUNT>
159

> <JCHEM_AVERAGE_POLARIZABILITY>
113.57464158721322

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
4

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(1S,2R,5S,10R,11S,14S,15S,16R)-14-acetyl-5-{[(2R,4S,5R,6R)-5-{[(2S,4R,5R,6R)-5-{[(2S,3R,4R,5R,6R)-5-{[(2S,3R,4S,5R,6R)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-3-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-11-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-16-yl (2E)-2-methylbut-2-enoate

> <ALOGPS_LOGP>
3.42

> <JCHEM_LOGP>
4.960218010000004

> <ALOGPS_LOGS>
-4.68

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
8

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
12.574743429030242

> <JCHEM_PKA_STRONGEST_ACIDIC>
12.02382931800416

> <JCHEM_PKA_STRONGEST_BASIC>
-3.2067140449656506

> <JCHEM_POLAR_SURFACE_AREA>
235.04999999999993

> <JCHEM_REFRACTIVITY>
260.01489999999995

> <JCHEM_ROTATABLE_BOND_COUNT>
16

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
2.18e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(1S,2R,5S,10R,11S,14S,15S,16R)-14-acetyl-5-{[(2R,4S,5R,6R)-5-{[(2S,4R,5R,6R)-5-{[(2S,3R,4R,5R,6R)-5-{[(2S,3R,4S,5R,6R)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-3-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-11-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-16-yl (2E)-2-methylbut-2-enoate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 28-APR-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   28-APR-22         0                                  
HETATM    1  C   UNK     0      11.519  -0.407   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      12.042   1.041   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      11.049   2.218   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       9.533   1.947   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       8.541   3.125   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       7.025   2.854   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       6.502   1.405   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       7.494   0.228   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       9.010   0.499   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      10.003  -0.678   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       8.487  -0.949   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       6.971  -1.221   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       5.455  -1.492   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       4.462  -0.314   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       4.986   1.134   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       3.770   2.079   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       2.495   1.215   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       2.923  -0.264   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       1.978  -1.480   0.000  0.00  0.00           C+0
HETATM   20  O   UNK     0       2.558  -2.907   0.000  0.00  0.00           O+0
HETATM   21  C   UNK     0       0.452  -1.269   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0       5.355   2.629   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0       3.791  -1.700   0.000  0.00  0.00           C+0
HETATM   24  O   UNK     0       4.932  -2.940   0.000  0.00  0.00           O+0
HETATM   25  C   UNK     0       5.925  -4.117   0.000  0.00  0.00           C+0
HETATM   26  O   UNK     0       7.441  -3.846   0.000  0.00  0.00           O+0
HETATM   27  C   UNK     0       5.401  -5.566   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       6.394  -6.743   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       5.871  -8.191   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       3.885  -5.837   0.000  0.00  0.00           C+0
HETATM   31  O   UNK     0      13.558   1.312   0.000  0.00  0.00           O+0
HETATM   32  C   UNK     0      14.081   2.761   0.000  0.00  0.00           C+0
HETATM   33  O   UNK     0      15.597   3.032   0.000  0.00  0.00           O+0
HETATM   34  C   UNK     0      16.120   4.480   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0      15.128   5.657   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0      13.612   5.386   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0      13.089   3.938   0.000  0.00  0.00           C+0
HETATM   38  O   UNK     0      12.619   6.564   0.000  0.00  0.00           O+0
HETATM   39  C   UNK     0      13.142   8.012   0.000  0.00  0.00           C+0
HETATM   40  O   UNK     0      15.651   7.106   0.000  0.00  0.00           O+0
HETATM   41  C   UNK     0      17.167   7.377   0.000  0.00  0.00           C+0
HETATM   42  C   UNK     0      17.690   8.825   0.000  0.00  0.00           C+0
HETATM   43  C   UNK     0      19.206   9.096   0.000  0.00  0.00           C+0
HETATM   44  C   UNK     0      20.199   7.919   0.000  0.00  0.00           C+0
HETATM   45  C   UNK     0      19.676   6.471   0.000  0.00  0.00           C+0
HETATM   46  O   UNK     0      18.160   6.199   0.000  0.00  0.00           O+0
HETATM   47  C   UNK     0      20.668   5.293   0.000  0.00  0.00           C+0
HETATM   48  O   UNK     0      21.715   8.190   0.000  0.00  0.00           O+0
HETATM   49  C   UNK     0      22.708   7.013   0.000  0.00  0.00           C+0
HETATM   50  O   UNK     0      22.184   5.564   0.000  0.00  0.00           O+0
HETATM   51  C   UNK     0      23.177   4.387   0.000  0.00  0.00           C+0
HETATM   52  C   UNK     0      24.693   4.658   0.000  0.00  0.00           C+0
HETATM   53  C   UNK     0      25.216   6.106   0.000  0.00  0.00           C+0
HETATM   54  C   UNK     0      24.223   7.284   0.000  0.00  0.00           C+0
HETATM   55  O   UNK     0      24.747   8.732   0.000  0.00  0.00           O+0
HETATM   56  O   UNK     0      26.732   6.377   0.000  0.00  0.00           O+0
HETATM   57  C   UNK     0      27.255   7.826   0.000  0.00  0.00           C+0
HETATM   58  O   UNK     0      25.686   3.481   0.000  0.00  0.00           O+0
HETATM   59  C   UNK     0      25.162   2.032   0.000  0.00  0.00           C+0
HETATM   60  C   UNK     0      26.155   0.855   0.000  0.00  0.00           C+0
HETATM   61  C   UNK     0      25.632  -0.593   0.000  0.00  0.00           C+0
HETATM   62  C   UNK     0      24.116  -0.864   0.000  0.00  0.00           C+0
HETATM   63  C   UNK     0      23.123   0.313   0.000  0.00  0.00           C+0
HETATM   64  O   UNK     0      23.647   1.761   0.000  0.00  0.00           O+0
HETATM   65  C   UNK     0      21.607   0.042   0.000  0.00  0.00           C+0
HETATM   66  O   UNK     0      23.593  -2.313   0.000  0.00  0.00           O+0
HETATM   67  O   UNK     0      26.625  -1.771   0.000  0.00  0.00           O+0
HETATM   68  C   UNK     0      26.101  -3.219   0.000  0.00  0.00           C+0
HETATM   69  O   UNK     0      27.671   1.126   0.000  0.00  0.00           O+0
HETATM   70  C   UNK     0      22.654   2.939   0.000  0.00  0.00           C+0
HETATM   71  O   UNK     0      19.729  10.545   0.000  0.00  0.00           O+0
HETATM   72  C   UNK     0      21.245  10.816   0.000  0.00  0.00           C+0
HETATM   73  C   UNK     0      17.636   4.751   0.000  0.00  0.00           C+0
CONECT    1    2   10                                                       
CONECT    2    1    3   31                                                  
CONECT    3    2    4                                                       
CONECT    4    3    5    9                                                  
CONECT    5    4    6                                                       
CONECT    6    5    7                                                       
CONECT    7    6    8   15                                                  
CONECT    8    7    9   12                                                  
CONECT    9    8    4   10   11                                             
CONECT   10    9    1                                                       
CONECT   11    9                                                            
CONECT   12    8   13                                                       
CONECT   13   12   14   24                                                  
CONECT   14   13   15   18   23                                             
CONECT   15   14    7   16   22                                             
CONECT   16   15   17                                                       
CONECT   17   16   18                                                       
CONECT   18   17   14   19                                                  
CONECT   19   18   20   21                                                  
CONECT   20   19                                                            
CONECT   21   19                                                            
CONECT   22   15                                                            
CONECT   23   14                                                            
CONECT   24   13   25                                                       
CONECT   25   24   26   27                                                  
CONECT   26   25                                                            
CONECT   27   25   28   30                                                  
CONECT   28   27   29                                                       
CONECT   29   28                                                            
CONECT   30   27                                                            
CONECT   31    2   32                                                       
CONECT   32   31   33   37                                                  
CONECT   33   32   34                                                       
CONECT   34   33   35   73                                                  
CONECT   35   34   36   40                                                  
CONECT   36   35   37   38                                                  
CONECT   37   36   32                                                       
CONECT   38   36   39                                                       
CONECT   39   38                                                            
CONECT   40   35   41                                                       
CONECT   41   40   42   46                                                  
CONECT   42   41   43                                                       
CONECT   43   42   44   71                                                  
CONECT   44   43   45   48                                                  
CONECT   45   44   46   47                                                  
CONECT   46   45   41                                                       
CONECT   47   45                                                            
CONECT   48   44   49                                                       
CONECT   49   48   50   54                                                  
CONECT   50   49   51                                                       
CONECT   51   50   52   70                                                  
CONECT   52   51   53   58                                                  
CONECT   53   52   54   56                                                  
CONECT   54   53   49   55                                                  
CONECT   55   54                                                            
CONECT   56   53   57                                                       
CONECT   57   56                                                            
CONECT   58   52   59                                                       
CONECT   59   58   60   64                                                  
CONECT   60   59   61   69                                                  
CONECT   61   60   62   67                                                  
CONECT   62   61   63   66                                                  
CONECT   63   62   64   65                                                  
CONECT   64   63   59                                                       
CONECT   65   63                                                            
CONECT   66   62                                                            
CONECT   67   61   68                                                       
CONECT   68   67                                                            
CONECT   69   60                                                            
CONECT   70   51                                                            
CONECT   71   43   72                                                       
CONECT   72   71                                                            
CONECT   73   34                                                            
MASTER        0    0    0    0    0    0    0    0   73    0  160    0
END

View in JSmol

Synonyms

Value	Source
(1S,2R,5S,10R,11S,14S,15S,16R)-14-Acetyl-5-{[(2R,4S,5R,6R)-5-{[(2S,4R,5R,6R)-5-{[(2S,3R,4R,5R,6R)-5-{[(2S,3R,4S,5R,6R)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-3-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-11-hydroxy-2,15-dimethyltetracyclo[8.7.0.0,.0,]heptadec-7-en-16-yl (2E)-2-methylbut-2-enoic acid	Generator

Chemical Formula

C₅₄H₈₆O₁₉

Average Mass

1039.2630 Da

Monoisotopic Mass

1038.57633 Da

IUPAC Name

Traditional Name

CAS Registry Number

Not Available

SMILES

CO[C@H]1C[C@H](O[C@H]2CC[C@]3(C)[C@H]4C[C@@H](OC(=O)C(\C)=C\C)[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC=C3C2)C(C)=O)O[C@H](C)[C@H]1O[C@H]1C[C@@H](OC)[C@H](O[C@@H]2O[C@H](C)[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](OC)[C@H]3O)[C@H](OC)[C@H]2O)[C@@H](C)O1

InChI Identifier

InChI=1S/C54H86O19/c1-14-25(2)49(59)70-38-22-35-34(54(60)20-18-33(26(3)55)53(38,54)9)16-15-31-21-32(17-19-52(31,35)8)69-39-23-36(61-10)44(28(5)65-39)71-40-24-37(62-11)45(29(6)66-40)72-51-43(58)48(64-13)46(30(7)68-51)73-50-42(57)47(63-12)41(56)27(4)67-50/h14-15,27-30,32-48,50-51,56-58,60H,16-24H2,1-13H3/b25-14+/t27-,28-,29-,30-,32+,33-,34-,35+,36+,37-,38-,39+,40+,41-,42-,43-,44-,45-,46-,47+,48-,50+,51+,52+,53+,54+/m1/s1

InChI Key

NGOPWLMMSZURID-FCVVVZLZSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Hoodia gordonii	Plant	KNApSAcK

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as steroidal glycosides. These are sterol lipids containing a carbohydrate moiety glycosidically linked to the steroid skeleton.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Steroids and steroid derivatives

Sub Class

Steroidal glycosides

Direct Parent

Steroidal glycosides

Alternative Parents

Substituents

Steroidal glycoside
Oligosaccharide
Pregnane-skeleton
Steroid ester
20-oxosteroid
Oxosteroid
Hydroxysteroid
14-hydroxysteroid
Delta-5-steroid
O-glycosyl compound
Glycosyl compound
Oxane
Alpha,beta-unsaturated carboxylic ester
Enoate ester
Tertiary alcohol
Cyclic alcohol
Secondary alcohol
Ketone
Carboxylic acid ester
Oxacycle
Organoheterocyclic compound
Monocarboxylic acid or derivatives
Ether
Dialkyl ether
Carboxylic acid derivative
Acetal
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Alcohol
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	3.42	ALOGPS
logP	4.96	ChemAxon
logS	-4.7	ALOGPS
pKa (Strongest Acidic)	12.02	ChemAxon
pKa (Strongest Basic)	-3.2	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	18	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	235.05 Å²	ChemAxon
Rotatable Bond Count	16	ChemAxon
Refractivity	260.01 m³·mol⁻¹	ChemAxon
Polarizability	113.57 Å³	ChemAxon
Number of Rings	8	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

163100716

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Not Available

Showing NP-Card for (-)-Hoodigoside D (NP0074436)

MOL for NP0074436 ((-)-Hoodigoside D)

3D MOL for NP0074436 ((-)-Hoodigoside D)

3D SDF for NP0074436 ((-)-Hoodigoside D)

3D-SDF for NP0074436 ((-)-Hoodigoside D)

PDB for NP0074436 ((-)-Hoodigoside D)

3D PDB for NP0074436 ((-)-Hoodigoside D)

SMILES for NP0074436 ((-)-Hoodigoside D)

INCHI for NP0074436 ((-)-Hoodigoside D)

Structure for NP0074436 ((-)-Hoodigoside D)

3D Structure for NP0074436 ((-)-Hoodigoside D)