NP-MRD: Showing NP-Card for Ginsenoside F1 (NP0071280)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-04-28 16:40:09 UTC

Updated at

2022-04-28 16:40:09 UTC

NP-MRD ID

NP0071280

Secondary Accession Numbers

None

Natural Product Identification

Common Name

Ginsenoside F1

Description

Ginsenoside F1 belongs to the class of organic compounds known as triterpene saponins. These are glycosylated derivatives of triterpene sapogenins. The sapogenin moiety backbone is usually based on the oleanane, ursane, taraxastane, bauerane, lanostane, lupeol, lupane, dammarane, cycloartane, friedelane, hopane, 9b,19-cyclo-lanostane, cycloartane, or cycloartanol skeleton. Ginsenoside F1 is found in Gynostemma yixingense, Panax ginseng , Panax notoginseng , Panax quinquefolium and Panax spp.. Ginsenoside F1 was first documented in 2021 (PMID: 34764724). Based on a literature review a small amount of articles have been published on ginsenoside F1 (PMID: 35058728) (PMID: 35054451) (PMID: 34535878) (PMID: 34301288).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652304282218402D          

 45 49  0  0  1  0            999 V2000
    4.2475    2.1537    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5278    1.3777    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.9960    0.7470    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1838    0.8922    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.9035    1.6682    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.4354    2.2989    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0914    1.8134    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.5596    1.1827    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.8399    0.4067    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6520    0.2615    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.9323   -0.5144    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7475    1.3279    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.4672    2.1038    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.9990    2.7345    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.8111    2.5893    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7187    3.5104    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3574    2.0770    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.5867    1.2845    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0962    0.8215    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8637    2.7283    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.3701    3.3797    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0592    4.1438    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.5655    4.7952    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2547    5.5593    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.4374    5.6722    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.0689    5.0209    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.2419    4.2567    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.2644    3.6054    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8862    5.1337    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1265    6.4364    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7610    6.2107    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4501    6.9749    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5151    2.2220    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2792    2.5329    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3921    3.3501    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1563    3.6610    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2691    4.4782    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8076    3.1546    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2124    3.2347    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9451    0.5269    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2487    0.4185    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6232    2.4441    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6077    0.1935    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8792   -0.0697    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3399    1.2325    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  4  3  1  6  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  1  6  1  0  0  0  0
  5  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
  4 10  1  0  0  0  0
 10 11  1  1  0  0  0
  8 12  1  0  0  0  0
 13 12  1  1  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
  7 15  1  6  0  0  0
 14 16  1  6  0  0  0
 13 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 12 19  1  0  0  0  0
 17 20  1  6  0  0  0
 20 21  1  6  0  0  0
 22 21  1  6  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 22 27  1  0  0  0  0
 27 28  1  1  0  0  0
 26 29  1  6  0  0  0
 25 30  1  1  0  0  0
 24 31  1  6  0  0  0
 31 32  1  0  0  0  0
 20 33  1  0  0  0  0
 33 34  1  0  0  0  0
 34 35  1  0  0  0  0
 35 36  2  0  0  0  0
 36 37  1  0  0  0  0
 36 38  1  0  0  0  0
 20 39  1  1  0  0  0
 12 40  1  1  0  0  0
  8 41  1  6  0  0  0
  5 42  1  6  0  0  0
  3 43  1  0  0  0  0
  3 44  1  0  0  0  0
  2 45  1  6  0  0  0
M  END

     RDKit          3D

107111  0  0  0  0  0  0  0  0999 V2000
   -6.3323    3.6441   -3.0170 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5020    3.6220   -1.8123 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9215    4.2948   -0.5469 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3298    2.9884   -1.8240 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4314    2.9079   -0.6808 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1188    1.6239   -0.0728 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4926    0.4864   -0.7122 C   0  0  2  0  0  0  0  0  0  0  0  0
   -3.3688    0.0329   -1.8600 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5349   -0.4949    0.3235 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6942   -0.9254    0.7862 C   0  0  2  0  0  0  0  0  0  0  0  0
   -3.8285   -0.3587    2.0998 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9157   -0.8848    2.7574 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.5545   -1.4749    4.1174 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0004   -0.4819    4.9496 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7922   -1.7950    1.9797 C   0  0  1  0  0  0  0  0  0  0  0  0
   -6.7571   -1.0949    1.2280 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1408   -2.8276    1.1426 C   0  0  2  0  0  0  0  0  0  0  0  0
   -5.2415   -4.1153    1.6606 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6926   -2.4286    0.9206 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.1895   -2.9840   -0.2452 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1061    0.4553   -1.1530 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.7462    1.5106   -2.1846 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7202    1.2013   -2.5461 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1441    0.3550   -1.3743 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.1354   -1.0715   -1.8678 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0527    0.5575   -0.2957 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.3150   -0.3120    0.8281 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.4929   -0.1038    1.9550 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7006    0.0579    1.4112 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6915   -0.1541    0.3492 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.1319   -0.3125    0.8043 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.5777    0.9730    1.4003 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2162   -1.3611    1.8816 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6308   -1.6132    2.2994 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.6533   -1.6191    1.2261 C   0  0  2  0  0  0  0  0  0  0  0  0
    7.6584   -0.6421    1.4275 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.1510   -1.5195   -0.1730 C   0  0  1  0  0  0  0  0  0  0  0  0
    7.3066   -0.9383   -0.9991 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0724   -2.9756   -0.6892 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8686   -0.8119   -0.3825 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.9110    0.2943   -1.4083 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.5377   -0.2292   -2.5583 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5203    0.6668   -1.8836 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4997    0.7713   -0.7983 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.4148    2.2296   -0.4152 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7557    3.4977   -3.9537 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.0834    2.8292   -2.9519 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.8152    4.6440   -3.1180 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1831    5.0787   -0.2848 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.8858    4.8422   -0.7069 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0146    3.5794    0.2856 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0445    2.5292   -2.7594 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9706    3.4988    0.1459 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5231    3.5840   -0.7993 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6602    1.8607    0.9580 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1314    1.2541    0.3186 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3334   -1.0589   -2.0485 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0172    0.4665   -2.8445 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4098    0.4124   -1.7846 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6415   -0.6478    0.3332 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5588    0.0133    3.0198 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.4401   -1.8469    4.6450 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7629   -2.2261    3.9827 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0920   -0.6892    5.8932 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4174   -2.3530    2.7432 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.4767   -1.7726    1.0250 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6064   -2.8211    0.1249 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.4089   -4.7516    0.9179 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0502   -2.7660    1.7677 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5353   -3.8878   -0.3593 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9689   -0.5018   -1.7570 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6554    2.5198   -1.7444 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2943    1.4580   -3.1141 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.3113    2.0854   -2.7454 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7471    0.6250   -3.5214 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.6412   -1.1661   -2.8869 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5397   -1.7725   -1.2587 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1085   -1.5348   -2.0154 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1682    1.6164    0.0412 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.3355   -1.3912    0.6989 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3959    0.8132    2.3129 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.8063   -0.6983    2.2456 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6698    1.0228    1.9065 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.4590   -1.1952   -0.0356 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.4820    0.8732    2.0720 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.8205    1.7738    0.7092 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.7803    1.2532    2.1561 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.7317   -0.9031    2.7968 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.6353   -2.2661    1.6669 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.9631   -0.8450    3.0608 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.6042   -2.5668    2.9100 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.2279   -2.5896    1.3578 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.5495   -0.9961    1.5328 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.4176   -1.4577   -1.9804 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.2785   -1.1928   -0.4784 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.2822    0.1455   -1.0557 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.7157   -3.6086    0.1698 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3183   -3.0643   -1.4821 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.0669   -3.3508   -0.9576 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.1857   -1.5697   -0.8820 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.5165    1.1623   -1.1074 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.9466   -0.8274   -3.0593 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.6828    1.6720   -2.3881 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.1813    0.0289   -2.7284 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3011    2.8169   -0.8126 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.3771    2.4435    0.6432 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5556    2.7755   -0.8673 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  2  4  2  3
  4  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  7  9  1  1
  9 10  1  0
 10 11  1  0
 11 12  1  0
 12 13  1  0
 13 14  1  0
 12 15  1  0
 15 16  1  0
 15 17  1  0
 17 18  1  0
 17 19  1  0
 19 20  1  0
  7 21  1  0
 21 22  1  0
 22 23  1  0
 23 24  1  0
 24 25  1  6
 24 26  1  0
 26 27  1  0
 27 28  1  0
 27 29  1  0
 29 30  1  0
 30 31  1  0
 31 32  1  1
 31 33  1  0
 33 34  1  0
 34 35  1  0
 35 36  1  0
 35 37  1  0
 37 38  1  6
 37 39  1  0
 37 40  1  0
 40 41  1  0
 41 42  1  0
 41 43  1  0
 43 44  1  0
 44 45  1  1
 19 10  1  0
 26 21  1  0
 44 30  1  0
 44 24  1  0
 40 31  1  0
  1 46  1  0
  1 47  1  0
  1 48  1  0
  3 49  1  0
  3 50  1  0
  3 51  1  0
  4 52  1  0
  5 53  1  0
  5 54  1  0
  6 55  1  0
  6 56  1  0
  8 57  1  0
  8 58  1  0
  8 59  1  0
 10 60  1  6
 12 61  1  1
 13 62  1  0
 13 63  1  0
 14 64  1  0
 15 65  1  1
 16 66  1  0
 17 67  1  6
 18 68  1  0
 19 69  1  1
 20 70  1  0
 21 71  1  6
 22 72  1  0
 22 73  1  0
 23 74  1  0
 23 75  1  0
 25 76  1  0
 25 77  1  0
 25 78  1  0
 26 79  1  1
 27 80  1  6
 28 81  1  0
 29 82  1  0
 29 83  1  0
 30 84  1  6
 32 85  1  0
 32 86  1  0
 32 87  1  0
 33 88  1  0
 33 89  1  0
 34 90  1  0
 34 91  1  0
 35 92  1  6
 36 93  1  0
 38 94  1  0
 38 95  1  0
 38 96  1  0
 39 97  1  0
 39 98  1  0
 39 99  1  0
 40100  1  6
 41101  1  1
 42102  1  0
 43103  1  0
 43104  1  0
 45105  1  0
 45106  1  0
 45107  1  0
M  END


  Mrv1652304282218402D          

 45 49  0  0  1  0            999 V2000
    4.2475    2.1537    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5278    1.3777    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.9960    0.7470    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1838    0.8922    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.9035    1.6682    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.4354    2.2989    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0914    1.8134    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.5596    1.1827    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.8399    0.4067    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6520    0.2615    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.9323   -0.5144    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7475    1.3279    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.4672    2.1038    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.9990    2.7345    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.8111    2.5893    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7187    3.5104    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3574    2.0770    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.5867    1.2845    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0962    0.8215    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8637    2.7283    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.3701    3.3797    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0592    4.1438    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.5655    4.7952    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2547    5.5593    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.4374    5.6722    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.0689    5.0209    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.2419    4.2567    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.2644    3.6054    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8862    5.1337    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1265    6.4364    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7610    6.2107    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4501    6.9749    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5151    2.2220    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2792    2.5329    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3921    3.3501    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1563    3.6610    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2691    4.4782    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8076    3.1546    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2124    3.2347    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9451    0.5269    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2487    0.4185    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6232    2.4441    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6077    0.1935    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8792   -0.0697    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3399    1.2325    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  4  3  1  6  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  1  6  1  0  0  0  0
  5  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
  4 10  1  0  0  0  0
 10 11  1  1  0  0  0
  8 12  1  0  0  0  0
 13 12  1  1  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
  7 15  1  6  0  0  0
 14 16  1  6  0  0  0
 13 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 12 19  1  0  0  0  0
 17 20  1  6  0  0  0
 20 21  1  6  0  0  0
 22 21  1  6  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 22 27  1  0  0  0  0
 27 28  1  1  0  0  0
 26 29  1  6  0  0  0
 25 30  1  1  0  0  0
 24 31  1  6  0  0  0
 31 32  1  0  0  0  0
 20 33  1  0  0  0  0
 33 34  1  0  0  0  0
 34 35  1  0  0  0  0
 35 36  2  0  0  0  0
 36 37  1  0  0  0  0
 36 38  1  0  0  0  0
 20 39  1  1  0  0  0
 12 40  1  1  0  0  0
  8 41  1  6  0  0  0
  5 42  1  6  0  0  0
  3 43  1  0  0  0  0
  3 44  1  0  0  0  0
  2 45  1  6  0  0  0
M  END
> <DATABASE_ID>
NP0071280

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(C)=CCC[C@](C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H]1CC[C@]2(C)[C@@H]1[C@H](O)C[C@@H]1[C@@]3(C)CC[C@H](O)C(C)(C)[C@@H]3[C@@H](O)C[C@@]21C

> <INCHI_IDENTIFIER>
InChI=1S/C36H62O9/c1-19(2)10-9-13-36(8,45-31-29(43)28(42)27(41)23(18-37)44-31)20-11-15-34(6)26(20)21(38)16-24-33(5)14-12-25(40)32(3,4)30(33)22(39)17-35(24,34)7/h10,20-31,37-43H,9,11-18H2,1-8H3/t20-,21+,22-,23+,24+,25-,26-,27+,28-,29+,30-,31-,33+,34+,35+,36-/m0/s1

> <INCHI_KEY>
XNGXWSFSJIQMNC-FIYORUNESA-N

> <FORMULA>
C36H62O9

> <MOLECULAR_WEIGHT>
638.883

> <EXACT_MASS>
638.439383576

> <JCHEM_ACCEPTOR_COUNT>
9

> <JCHEM_ATOM_COUNT>
107

> <JCHEM_AVERAGE_POLARIZABILITY>
71.67611823735126

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
7

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{[(2S)-6-methyl-2-[(1R,2R,5S,7R,8S,10R,11R,14S,15R,16R)-5,8,16-trihydroxy-2,6,6,10,11-pentamethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]hept-5-en-2-yl]oxy}oxane-3,4,5-triol

> <ALOGPS_LOGP>
2.68

> <JCHEM_LOGP>
2.4523373623333296

> <ALOGPS_LOGS>
-3.94

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
13.173211080810518

> <JCHEM_PKA_STRONGEST_ACIDIC>
12.207015827438074

> <JCHEM_PKA_STRONGEST_BASIC>
-2.838907696472149

> <JCHEM_POLAR_SURFACE_AREA>
160.07

> <JCHEM_REFRACTIVITY>
171.24170000000004

> <JCHEM_ROTATABLE_BOND_COUNT>
7

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
7.34e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{[(2S)-6-methyl-2-[(1R,2R,5S,7R,8S,10R,11R,14S,15R,16R)-5,8,16-trihydroxy-2,6,6,10,11-pentamethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]hept-5-en-2-yl]oxy}oxane-3,4,5-triol

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 28-APR-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   28-APR-22         0                                  
HETATM    1  C   UNK     0       7.929   4.020   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       8.452   2.572   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       7.459   1.394   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       5.943   1.666   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       5.420   3.114   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       6.413   4.291   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       3.904   3.385   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       2.911   2.208   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       3.434   0.759   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       4.950   0.488   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0       5.474  -0.960   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0       1.395   2.479   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       0.872   3.927   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       1.865   5.104   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       3.381   4.833   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0       1.342   6.553   0.000  0.00  0.00           O+0
HETATM   17  C   UNK     0      -0.667   3.877   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      -1.095   2.398   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       0.179   1.534   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      -1.612   5.093   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0      -2.557   6.309   0.000  0.00  0.00           O+0
HETATM   22  C   UNK     0      -1.977   7.735   0.000  0.00  0.00           C+0
HETATM   23  O   UNK     0      -2.922   8.951   0.000  0.00  0.00           O+0
HETATM   24  C   UNK     0      -2.342  10.377   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0      -0.816  10.588   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       0.129   9.372   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0      -0.452   7.946   0.000  0.00  0.00           C+0
HETATM   28  O   UNK     0       0.494   6.730   0.000  0.00  0.00           O+0
HETATM   29  O   UNK     0       1.654   9.583   0.000  0.00  0.00           O+0
HETATM   30  O   UNK     0      -0.236  12.015   0.000  0.00  0.00           O+0
HETATM   31  C   UNK     0      -3.287  11.593   0.000  0.00  0.00           C+0
HETATM   32  O   UNK     0      -2.707  13.020   0.000  0.00  0.00           O+0
HETATM   33  C   UNK     0      -2.828   4.148   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0      -4.255   4.728   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0      -4.465   6.254   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0      -5.892   6.834   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0      -6.102   8.359   0.000  0.00  0.00           C+0
HETATM   38  C   UNK     0      -7.108   5.889   0.000  0.00  0.00           C+0
HETATM   39  C   UNK     0      -0.396   6.038   0.000  0.00  0.00           C+0
HETATM   40  C   UNK     0       1.764   0.984   0.000  0.00  0.00           C+0
HETATM   41  C   UNK     0       2.331   0.781   0.000  0.00  0.00           C+0
HETATM   42  C   UNK     0       4.897   4.562   0.000  0.00  0.00           C+0
HETATM   43  C   UNK     0       8.601   0.361   0.000  0.00  0.00           C+0
HETATM   44  C   UNK     0       7.241  -0.130   0.000  0.00  0.00           C+0
HETATM   45  O   UNK     0       9.968   2.301   0.000  0.00  0.00           O+0
CONECT    1    2    6                                                       
CONECT    2    1    3   45                                                  
CONECT    3    2    4   43   44                                             
CONECT    4    3    5   10                                                  
CONECT    5    4    6    7   42                                             
CONECT    6    5    1                                                       
CONECT    7    5    8   15                                                  
CONECT    8    7    9   12   41                                             
CONECT    9    8   10                                                       
CONECT   10    9    4   11                                                  
CONECT   11   10                                                            
CONECT   12    8   13   19   40                                             
CONECT   13   12   14   17                                                  
CONECT   14   13   15   16                                                  
CONECT   15   14    7                                                       
CONECT   16   14                                                            
CONECT   17   13   18   20                                                  
CONECT   18   17   19                                                       
CONECT   19   18   12                                                       
CONECT   20   17   21   33   39                                             
CONECT   21   20   22                                                       
CONECT   22   21   23   27                                                  
CONECT   23   22   24                                                       
CONECT   24   23   25   31                                                  
CONECT   25   24   26   30                                                  
CONECT   26   25   27   29                                                  
CONECT   27   26   22   28                                                  
CONECT   28   27                                                            
CONECT   29   26                                                            
CONECT   30   25                                                            
CONECT   31   24   32                                                       
CONECT   32   31                                                            
CONECT   33   20   34                                                       
CONECT   34   33   35                                                       
CONECT   35   34   36                                                       
CONECT   36   35   37   38                                                  
CONECT   37   36                                                            
CONECT   38   36                                                            
CONECT   39   20                                                            
CONECT   40   12                                                            
CONECT   41    8                                                            
CONECT   42    5                                                            
CONECT   43    3                                                            
CONECT   44    3                                                            
CONECT   45    2                                                            
MASTER        0    0    0    0    0    0    0    0   45    0   98    0
END

View in JSmol

Synonyms

Value	Source
(20S)-Ginsenoside F1	ChEBI
Ginsenoside g-F1	MeSH

Chemical Formula

C₃₆H₆₂O₉

Average Mass

638.8830 Da

Monoisotopic Mass

638.43938 Da

IUPAC Name

(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{[(2S)-6-methyl-2-[(1R,2R,5S,7R,8S,10R,11R,14S,15R,16R)-5,8,16-trihydroxy-2,6,6,10,11-pentamethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]hept-5-en-2-yl]oxy}oxane-3,4,5-triol

Traditional Name

CAS Registry Number

Not Available

SMILES

CC(C)=CCC[C@](C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H]1CC[C@]2(C)[C@@H]1[C@H](O)C[C@@H]1[C@@]3(C)CC[C@H](O)C(C)(C)[C@@H]3[C@@H](O)C[C@@]21C

InChI Identifier

InChI=1S/C36H62O9/c1-19(2)10-9-13-36(8,45-31-29(43)28(42)27(41)23(18-37)44-31)20-11-15-34(6)26(20)21(38)16-24-33(5)14-12-25(40)32(3,4)30(33)22(39)17-35(24,34)7/h10,20-31,37-43H,9,11-18H2,1-8H3/t20-,21+,22-,23+,24+,25-,26-,27+,28-,29+,30-,31-,33+,34+,35+,36-/m0/s1

InChI Key

XNGXWSFSJIQMNC-FIYORUNESA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Gynostemma yixingense	LOTUS Database	35616633
Panax ginseng	Plant	KNApSAcK
Panax notoginseng	Plant	KNApSAcK
Panax quinquefolius	Plant	KNApSAcK
Panax spp.	Plant	KNApSAcK

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as triterpene saponins. These are glycosylated derivatives of triterpene sapogenins. The sapogenin moiety backbone is usually based on the oleanane, ursane, taraxastane, bauerane, lanostane, lupeol, lupane, dammarane, cycloartane, friedelane, hopane, 9b,19-cyclo-lanostane, cycloartane, or cycloartanol skeleton.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Terpene glycosides

Direct Parent

Triterpene saponins

Alternative Parents

Substituents

Triterpene saponin
Triterpenoid
3-hydroxysteroid
14-alpha-methylsteroid
12-hydroxysteroid
6-hydroxysteroid
Hydroxysteroid
3-beta-hydroxysteroid
Steroid
Fatty acyl glycoside
Fatty acyl glycoside of mono- or disaccharide
Alkyl glycoside
Glycosyl compound
O-glycosyl compound
Monosaccharide
Fatty acyl
Oxane
Cyclic alcohol
Secondary alcohol
Oxacycle
Organoheterocyclic compound
Acetal
Polyol
Organooxygen compound
Hydrocarbon derivative
Organic oxygen compound
Primary alcohol
Alcohol
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

3beta-hydroxy steroid (CHEBI:77150 )
beta-D-glucoside (CHEBI:77150 )
6alpha-hydroxy steroid (CHEBI:77150 )
tetracyclic triterpenoid (CHEBI:77150 )
12beta-hydroxy steroid (CHEBI:77150 )
ginsenoside (CHEBI:77150 )

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	2.68	ALOGPS
logP	2.45	ChemAxon
logS	-3.9	ALOGPS
pKa (Strongest Acidic)	12.21	ChemAxon
pKa (Strongest Basic)	-2.8	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	9	ChemAxon
Hydrogen Donor Count	7	ChemAxon
Polar Surface Area	160.07 Å²	ChemAxon
Rotatable Bond Count	7	ChemAxon
Refractivity	171.24 m³·mol⁻¹	ChemAxon
Polarizability	71.68 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

C00030388

Chemspider ID

7985298

KEGG Compound ID

Not Available

BioCyc ID

CPD-15448

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

9809542

PDB ID

Not Available

ChEBI ID

77150

Good Scents ID

rw1878371

References

General References

Hou J, Jeon B, Baek J, Yun Y, Kim D, Chang B, Kim S, Kim S: High fat diet-induced brain damaging effects through autophagy-mediated senescence, inflammation and apoptosis mitigated by ginsenoside F1-enhanced mixture. J Ginseng Res. 2022 Jan;46(1):79-90. doi: 10.1016/j.jgr.2021.04.002. Epub 2021 Apr 16. [PubMed:35058728 ]
Yun YJ, Park BH, Hou J, Oh JP, Han JH, Kim SC: Ginsenoside F1 Protects the Brain against Amyloid Beta-Induced Toxicity by Regulating IDE and NEP. Life (Basel). 2022 Jan 1;12(1). pii: life12010058. doi: 10.3390/life12010058. [PubMed:35054451 ]
Kim SJ, Lee J, Choi WS, Kim HJ, Kim MY, Kim SC, Kim HS: Ginsenoside F1 Attenuates Eosinophilic Inflammation in Chronic Rhinosinusitis by Promoting NK Cell Function. J Ginseng Res. 2021 Nov;45(6):695-705. doi: 10.1016/j.jgr.2021.03.007. Epub 2021 Mar 29. [PubMed:34764724 ]
Chun YL, Lee S, Park KH, Park C, Huh Y, Jeong NY, Jung J: Protective and therapeutic effect of (S)-ginsenoside F1 on peripheral nerve degeneration targeting Schwann cells: a pharmaco-neuroanatomical approach. Anat Sci Int. 2022 Jan;97(1):79-89. doi: 10.1007/s12565-021-00630-x. Epub 2021 Sep 17. [PubMed:34535878 ]
Wang L, Chen MY, Shao L, Zhang W, Li XP, Huang WH: Personalized bioconversion of Panax notoginseng saponins mediated by gut microbiota between two different diet-pattern healthy subjects. Chin Med. 2021 Jul 23;16(1):60. doi: 10.1186/s13020-021-00476-5. [PubMed:34301288 ]

Showing NP-Card for Ginsenoside F1 (NP0071280)

MOL for NP0071280 (Ginsenoside F1)

3D MOL for NP0071280 (Ginsenoside F1)

3D SDF for NP0071280 (Ginsenoside F1)

3D-SDF for NP0071280 (Ginsenoside F1)

PDB for NP0071280 (Ginsenoside F1)

3D PDB for NP0071280 (Ginsenoside F1)

SMILES for NP0071280 (Ginsenoside F1)

INCHI for NP0071280 (Ginsenoside F1)

Structure for NP0071280 (Ginsenoside F1)

3D Structure for NP0071280 (Ginsenoside F1)