NP-MRD: Showing NP-Card for Pittosporanoside A1 (NP0064271)

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Record Information

Version

2.0

Created at

2022-04-28 08:32:08 UTC

Updated at

2022-04-28 08:32:08 UTC

NP-MRD ID

NP0064271

Secondary Accession Numbers

None

Natural Product Identification

Common Name

Pittosporanoside A1

Description

(2S,3R,4S,5S,6R)-2-{[(1aS,1bR,2S,4aR,5R,7aS)-1,1,2,5-tetramethyl-decahydro-1H-cyclopropa[e]azulen-5-yl]oxy}-3-(acetyloxy)-5-hydroxy-6-methyloxan-4-yl (2E)-2-methylbut-2-enoate belongs to the class of organic compounds known as terpene glycosides. These are prenol lipids containing a carbohydrate moiety glycosidically bound to a terpene backbone. Pittosporanoside A1 is found in Pittosporum tobira . Based on a literature review very few articles have been published on (2S,3R,4S,5S,6R)-2-{[(1aS,1bR,2S,4aR,5R,7aS)-1,1,2,5-tetramethyl-decahydro-1H-cyclopropa[e]azulen-5-yl]oxy}-3-(acetyloxy)-5-hydroxy-6-methyloxan-4-yl (2E)-2-methylbut-2-enoate.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652304282210322D          

 35 38  0  0  1  0            999 V2000
    1.8983    1.9219    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
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  1 34  1  6  0  0  0
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M  END

     RDKit          3D

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M  END


  Mrv1652304282210322D          

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  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  1  7  1  0  0  0  0
  7  8  1  6  0  0  0
  7  9  1  1  0  0  0
 10  9  1  6  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 10 15  1  0  0  0  0
 14 16  1  6  0  0  0
 13 17  1  6  0  0  0
 12 18  1  6  0  0  0
 18 19  1  0  0  0  0
 19 20  2  0  0  0  0
 19 21  1  0  0  0  0
 21 22  2  0  0  0  0
 22 23  1  0  0  0  0
 21 24  1  0  0  0  0
 11 25  1  1  0  0  0
 25 26  1  0  0  0  0
 26 27  2  0  0  0  0
 26 28  1  0  0  0  0
  4 29  1  0  0  0  0
  3 29  1  0  0  0  0
 29 30  1  0  0  0  0
 29 31  1  0  0  0  0
  2 32  1  0  0  0  0
 32 33  1  0  0  0  0
 33 34  1  0  0  0  0
  1 34  1  6  0  0  0
 32 35  1  6  0  0  0
M  END
> <DATABASE_ID>
NP0064271

> <DATABASE_NAME>
NP-MRD

> <SMILES>
C\C=C(/C)C(=O)O[C@H]1[C@@H](O)[C@@H](C)O[C@@H](O[C@]2(C)CC[C@H]3[C@H]([C@H]4[C@@H](C)CC[C@@H]24)C3(C)C)[C@@H]1OC(C)=O

> <INCHI_IDENTIFIER>
InChI=1S/C28H44O7/c1-9-14(2)25(31)34-23-22(30)16(4)32-26(24(23)33-17(5)29)35-28(8)13-12-19-21(27(19,6)7)20-15(3)10-11-18(20)28/h9,15-16,18-24,26,30H,10-13H2,1-8H3/b14-9+/t15-,16+,18+,19-,20-,21+,22-,23-,24+,26-,28+/m0/s1

> <INCHI_KEY>
AOLXWOJZYPAABO-XUGQIHMKSA-N

> <FORMULA>
C28H44O7

> <MOLECULAR_WEIGHT>
492.653

> <EXACT_MASS>
492.308703757

> <JCHEM_ACCEPTOR_COUNT>
5

> <JCHEM_ATOM_COUNT>
79

> <JCHEM_AVERAGE_POLARIZABILITY>
54.94301490679533

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2S,3R,4S,5S,6R)-2-{[(1aS,1bR,2S,4aR,5R,7aS)-1,1,2,5-tetramethyl-decahydro-1H-cyclopropa[e]azulen-5-yl]oxy}-3-(acetyloxy)-5-hydroxy-6-methyloxan-4-yl (2E)-2-methylbut-2-enoate

> <ALOGPS_LOGP>
4.53

> <JCHEM_LOGP>
5.108639385

> <ALOGPS_LOGS>
-5.10

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_ACIDIC>
13.104323719429043

> <JCHEM_PKA_STRONGEST_BASIC>
-3.6279688051217365

> <JCHEM_POLAR_SURFACE_AREA>
91.29000000000002

> <JCHEM_REFRACTIVITY>
130.4509

> <JCHEM_ROTATABLE_BOND_COUNT>
7

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
3.93e-03 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(2S,3R,4S,5S,6R)-2-{[(1aS,1bR,2S,4aR,5R,7aS)-1,1,2,5-tetramethyl-octahydro-1aH-cyclopropa[e]azulen-5-yl]oxy}-3-(acetyloxy)-5-hydroxy-6-methyloxan-4-yl (2E)-2-methylbut-2-enoate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 28-APR-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   28-APR-22         0                                  
HETATM    1  C   UNK     0       3.543   3.587   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       2.713   2.290   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       1.182   2.130   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       0.102   3.228   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       0.287   4.757   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       1.597   5.566   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       3.047   5.045   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       3.535   6.506   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0       4.515   5.509   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0       4.848   7.013   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       6.316   7.476   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       6.649   8.980   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       5.513  10.020   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       4.045   9.556   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0       3.712   8.053   0.000  0.00  0.00           O+0
HETATM   16  C   UNK     0       2.909  10.596   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0       5.846  11.524   0.000  0.00  0.00           O+0
HETATM   18  O   UNK     0       8.117   9.444   0.000  0.00  0.00           O+0
HETATM   19  C   UNK     0       8.450  10.948   0.000  0.00  0.00           C+0
HETATM   20  O   UNK     0       7.314  11.987   0.000  0.00  0.00           O+0
HETATM   21  C   UNK     0       9.919  11.411   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      10.251  12.915   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      11.720  13.379   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      11.054  10.372   0.000  0.00  0.00           C+0
HETATM   25  O   UNK     0       7.452   6.437   0.000  0.00  0.00           O+0
HETATM   26  C   UNK     0       7.120   4.933   0.000  0.00  0.00           C+0
HETATM   27  O   UNK     0       5.651   4.469   0.000  0.00  0.00           O+0
HETATM   28  C   UNK     0       8.256   3.893   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0      -0.309   1.744   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0      -1.828   1.489   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0      -0.589   0.230   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       3.691   1.100   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0       5.125   1.662   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0       5.034   3.199   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       3.302  -0.390   0.000  0.00  0.00           C+0
CONECT    1    2    7   34                                                  
CONECT    2    1    3   32                                                  
CONECT    3    2    4   29                                                  
CONECT    4    3    5   29                                                  
CONECT    5    4    6                                                       
CONECT    6    5    7                                                       
CONECT    7    6    1    8    9                                             
CONECT    8    7                                                            
CONECT    9    7   10                                                       
CONECT   10    9   11   15                                                  
CONECT   11   10   12   25                                                  
CONECT   12   11   13   18                                                  
CONECT   13   12   14   17                                                  
CONECT   14   13   15   16                                                  
CONECT   15   14   10                                                       
CONECT   16   14                                                            
CONECT   17   13                                                            
CONECT   18   12   19                                                       
CONECT   19   18   20   21                                                  
CONECT   20   19                                                            
CONECT   21   19   22   24                                                  
CONECT   22   21   23                                                       
CONECT   23   22                                                            
CONECT   24   21                                                            
CONECT   25   11   26                                                       
CONECT   26   25   27   28                                                  
CONECT   27   26                                                            
CONECT   28   26                                                            
CONECT   29    4    3   30   31                                             
CONECT   30   29                                                            
CONECT   31   29                                                            
CONECT   32    2   33   35                                                  
CONECT   33   32   34                                                       
CONECT   34   33    1                                                       
CONECT   35   32                                                            
MASTER        0    0    0    0    0    0    0    0   35    0   76    0
END

View in JSmol

Synonyms

Value	Source
(2S,3R,4S,5S,6R)-2-{[(1as,1BR,2S,4ar,5R,7as)-1,1,2,5-tetramethyl-decahydro-1H-cyclopropa[e]azulen-5-yl]oxy}-3-(acetyloxy)-5-hydroxy-6-methyloxan-4-yl (2E)-2-methylbut-2-enoic acid	Generator

Chemical Formula

C₂₈H₄₄O₇

Average Mass

492.6530 Da

Monoisotopic Mass

492.30870 Da

IUPAC Name

(2S,3R,4S,5S,6R)-2-{[(1aS,1bR,2S,4aR,5R,7aS)-1,1,2,5-tetramethyl-decahydro-1H-cyclopropa[e]azulen-5-yl]oxy}-3-(acetyloxy)-5-hydroxy-6-methyloxan-4-yl (2E)-2-methylbut-2-enoate

Traditional Name

(2S,3R,4S,5S,6R)-2-{[(1aS,1bR,2S,4aR,5R,7aS)-1,1,2,5-tetramethyl-octahydro-1aH-cyclopropa[e]azulen-5-yl]oxy}-3-(acetyloxy)-5-hydroxy-6-methyloxan-4-yl (2E)-2-methylbut-2-enoate

CAS Registry Number

Not Available

SMILES

C\C=C(/C)C(=O)O[C@H]1[C@@H](O)[C@@H](C)O[C@@H](O[C@]2(C)CC[C@H]3[C@H]([C@H]4[C@@H](C)CC[C@@H]24)C3(C)C)[C@@H]1OC(C)=O

InChI Identifier

InChI=1S/C28H44O7/c1-9-14(2)25(31)34-23-22(30)16(4)32-26(24(23)33-17(5)29)35-28(8)13-12-19-21(27(19,6)7)20-15(3)10-11-18(20)28/h9,15-16,18-24,26,30H,10-13H2,1-8H3/b14-9+/t15-,16+,18+,19-,20-,21+,22-,23-,24+,26-,28+/m0/s1

InChI Key

AOLXWOJZYPAABO-XUGQIHMKSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Pittosporum tobira	Plant	KNApSAcK

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as terpene glycosides. These are prenol lipids containing a carbohydrate moiety glycosidically bound to a terpene backbone.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Terpene glycosides

Direct Parent

Terpene glycosides

Alternative Parents

Substituents

Terpene glycoside
5,10-cycloaromadendrane sesquiterpenoid
Sesquiterpenoid
Guaiane sesquiterpenoid
Aromadendrane sesquiterpenoid
Hexose monosaccharide
O-glycosyl compound
Glycosyl compound
Fatty acid ester
Fatty acyl
Oxane
Monosaccharide
Dicarboxylic acid or derivatives
Alpha,beta-unsaturated carboxylic ester
Enoate ester
Secondary alcohol
Carboxylic acid ester
Oxacycle
Organoheterocyclic compound
Carboxylic acid derivative
Acetal
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Alcohol
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	4.53	ALOGPS
logP	5.11	ChemAxon
logS	-5.1	ALOGPS
pKa (Strongest Acidic)	13.1	ChemAxon
pKa (Strongest Basic)	-3.6	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	5	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	91.29 Å²	ChemAxon
Rotatable Bond Count	7	ChemAxon
Refractivity	130.45 m³·mol⁻¹	ChemAxon
Polarizability	54.94 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

162950590

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Not Available

Showing NP-Card for Pittosporanoside A1 (NP0064271)

MOL for NP0064271 (Pittosporanoside A1)

3D MOL for NP0064271 (Pittosporanoside A1)

3D SDF for NP0064271 (Pittosporanoside A1)

3D-SDF for NP0064271 (Pittosporanoside A1)

PDB for NP0064271 (Pittosporanoside A1)

3D PDB for NP0064271 (Pittosporanoside A1)

SMILES for NP0064271 (Pittosporanoside A1)

INCHI for NP0064271 (Pittosporanoside A1)

Structure for NP0064271 (Pittosporanoside A1)

3D Structure for NP0064271 (Pittosporanoside A1)