NP-MRD: Showing NP-Card for Perrottetin C (NP0061355)

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Record Information

Version

2.0

Created at

2022-04-28 06:10:39 UTC

Updated at

2022-04-28 06:10:39 UTC

NP-MRD ID

NP0061355

Secondary Accession Numbers

None

Natural Product Identification

Common Name

Perrottetin C

Description

4-(3-Hydroxy-3-methylbutyl)-5-(2-phenylethyl)benzene-1,2,3-triol belongs to the class of organic compounds known as stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 ) are derived from the common phenylpropene (C6-C3) skeleton building block. The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. Perrottetin C is found in Radula perrottetii. Based on a literature review very few articles have been published on 4-(3-Hydroxy-3-methylbutyl)-5-(2-phenylethyl)benzene-1,2,3-triol.

Structure

MOL 3D MOL SDF PDB SMILES InChI

     RDKit          3D

 47 48  0  0  0  0  0  0  0  0999 V2000
   -3.8893   -1.5364    0.5492 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5426   -1.8292   -0.0298 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7906   -2.6731    0.9475 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7161   -2.5457   -1.2090 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7832   -0.5640   -0.4028 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5498    0.3232    0.7588 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8686    1.5867    0.5660 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4775    1.7300    0.4838 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4093    0.6262    0.4834 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8578    0.0832   -0.8275 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7652   -1.1230   -0.6178 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1096   -0.9871   -0.4393 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8951   -2.0983   -0.2451 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3033   -3.3279   -0.2356 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9539   -3.5221   -0.4127 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1815   -2.3609   -0.6072 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0446    3.0091    0.3508 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2662    4.1487    0.2986 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8088    5.4072    0.1664 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0981    4.0188    0.3815 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9551    5.0831    0.3434 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6229    2.7724    0.5099 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0172    2.5956    0.5938 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3668   -0.6100    0.1293 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5662   -2.3714    0.2715 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8866   -1.5113    1.6615 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8274   -3.0146    0.5661 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7276   -2.1428    1.9109 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4150   -3.5875    1.1668 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9598   -1.9572   -1.9735 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3525   -0.0281   -1.2075 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8442   -0.9113   -0.8502 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1038   -0.2767    1.6080 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5828    0.5436    1.1792 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.3552    0.9679    1.0156 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.0897   -0.2472    1.0995 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.4792    0.8955   -1.3125 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1140   -0.2097   -1.5505 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.5779    0.0000   -0.4530 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.9821   -1.9957   -0.0946 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.9731   -4.1900   -0.0708 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.5433   -4.5104   -0.3992 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1131   -2.5185   -0.7479 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1108    3.1298    0.2779 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.3079    6.2652    0.1963 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6722    6.0376    0.2541 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5806    3.4263    0.5508 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  2  4  1  0
  2  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  2  0
  8  9  1  0
  9 10  1  0
 10 11  1  0
 11 12  2  0
 12 13  1  0
 13 14  2  0
 14 15  1  0
 15 16  2  0
  8 17  1  0
 17 18  2  0
 18 19  1  0
 18 20  1  0
 20 21  1  0
 20 22  2  0
 22 23  1  0
 22  7  1  0
 16 11  1  0
  1 24  1  0
  1 25  1  0
  1 26  1  0
  3 27  1  0
  3 28  1  0
  3 29  1  0
  4 30  1  0
  5 31  1  0
  5 32  1  0
  6 33  1  0
  6 34  1  0
  9 35  1  0
  9 36  1  0
 10 37  1  0
 10 38  1  0
 12 39  1  0
 13 40  1  0
 14 41  1  0
 15 42  1  0
 16 43  1  0
 17 44  1  0
 19 45  1  0
 21 46  1  0
 23 47  1  0
M  END


  Mrv1652304282208102D          

 23 24  0  0  0  0            999 V2000
    2.1434   -3.7125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -4.1250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -3.7125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8579   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5559    0.3020    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7309   -1.1270    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  1  6  1  0  0  0  0
  5  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 11 12  2  0  0  0  0
 12 13  1  0  0  0  0
 13 14  2  0  0  0  0
  9 14  1  0  0  0  0
 13 15  1  0  0  0  0
 12 16  1  0  0  0  0
 11 17  1  0  0  0  0
 10 18  1  0  0  0  0
 18 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 20 22  1  0  0  0  0
 20 23  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0061355

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(C)(O)CCC1=C(CCC2=CC=CC=C2)C=C(O)C(O)=C1O

> <INCHI_IDENTIFIER>
InChI=1S/C19H24O4/c1-19(2,23)11-10-15-14(12-16(20)18(22)17(15)21)9-8-13-6-4-3-5-7-13/h3-7,12,20-23H,8-11H2,1-2H3

> <INCHI_KEY>
MXHQUNFQIBEKCQ-UHFFFAOYSA-N

> <FORMULA>
C19H24O4

> <MOLECULAR_WEIGHT>
316.397

> <EXACT_MASS>
316.167459253

> <JCHEM_ACCEPTOR_COUNT>
4

> <JCHEM_ATOM_COUNT>
47

> <JCHEM_AVERAGE_POLARIZABILITY>
35.1652070097912

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
4

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
4-(3-hydroxy-3-methylbutyl)-5-(2-phenylethyl)benzene-1,2,3-triol

> <ALOGPS_LOGP>
3.08

> <JCHEM_LOGP>
4.261944338666667

> <ALOGPS_LOGS>
-3.88

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
11.535360442371301

> <JCHEM_PKA_STRONGEST_ACIDIC>
9.327111569012365

> <JCHEM_PKA_STRONGEST_BASIC>
-2.6304116617184663

> <JCHEM_POLAR_SURFACE_AREA>
80.92

> <JCHEM_REFRACTIVITY>
91.56780000000002

> <JCHEM_ROTATABLE_BOND_COUNT>
6

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
4.13e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
4-(3-hydroxy-3-methylbutyl)-5-(2-phenylethyl)benzene-1,2,3-triol

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 28-APR-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   28-APR-22         0                                  
HETATM    1  C   UNK     0       4.001  -6.930   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       2.667  -7.700   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       1.334  -6.930   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       1.334  -5.390   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       2.667  -4.620   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       4.001  -5.390   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       2.667  -3.080   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       1.334  -2.310   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       1.334  -0.770   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       0.000   0.000   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       0.000   1.540   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       1.334   2.310   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       2.667   1.540   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       2.667   0.000   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0       4.001   2.310   0.000  0.00  0.00           O+0
HETATM   16  O   UNK     0       1.334   3.850   0.000  0.00  0.00           O+0
HETATM   17  O   UNK     0      -1.334   2.310   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0      -1.334  -0.770   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      -2.667   0.000   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      -4.001  -0.770   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      -5.335  -1.540   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      -4.771   0.564   0.000  0.00  0.00           C+0
HETATM   23  O   UNK     0      -3.231  -2.104   0.000  0.00  0.00           O+0
CONECT    1    2    6                                                       
CONECT    2    1    3                                                       
CONECT    3    2    4                                                       
CONECT    4    3    5                                                       
CONECT    5    4    6    7                                                  
CONECT    6    5    1                                                       
CONECT    7    5    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8   10   14                                                  
CONECT   10    9   11   18                                                  
CONECT   11   10   12   17                                                  
CONECT   12   11   13   16                                                  
CONECT   13   12   14   15                                                  
CONECT   14   13    9                                                       
CONECT   15   13                                                            
CONECT   16   12                                                            
CONECT   17   11                                                            
CONECT   18   10   19                                                       
CONECT   19   18   20                                                       
CONECT   20   19   21   22   23                                             
CONECT   21   20                                                            
CONECT   22   20                                                            
CONECT   23   20                                                            
MASTER        0    0    0    0    0    0    0    0   23    0   48    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₁₉H₂₄O₄

Average Mass

316.3970 Da

Monoisotopic Mass

316.16746 Da

IUPAC Name

4-(3-hydroxy-3-methylbutyl)-5-(2-phenylethyl)benzene-1,2,3-triol

Traditional Name

4-(3-hydroxy-3-methylbutyl)-5-(2-phenylethyl)benzene-1,2,3-triol

CAS Registry Number

Not Available

SMILES

CC(C)(O)CCC1=C(CCC2=CC=CC=C2)C=C(O)C(O)=C1O

InChI Identifier

InChI=1S/C19H24O4/c1-19(2,23)11-10-15-14(12-16(20)18(22)17(15)21)9-8-13-6-4-3-5-7-13/h3-7,12,20-23H,8-11H2,1-2H3

InChI Key

MXHQUNFQIBEKCQ-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Radula perrottetii	-	KNApSAcK

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 ) are derived from the common phenylpropene (C6-C3) skeleton building block. The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids.

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Stilbenes

Sub Class

Not Available

Direct Parent

Stilbenes

Alternative Parents

Substituents

Stilbene
Pyrogallol derivative
Benzenetriol
1-hydroxy-4-unsubstituted benzenoid
1-hydroxy-2-unsubstituted benzenoid
Phenol
Benzenoid
Monocyclic benzene moiety
Tertiary alcohol
Polyol
Organic oxygen compound
Hydrocarbon derivative
Organooxygen compound
Alcohol
Aromatic homomonocyclic compound

Molecular Framework

Aromatic homomonocyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	3.08	ALOGPS
logP	4.26	ChemAxon
logS	-3.9	ALOGPS
pKa (Strongest Acidic)	9.33	ChemAxon
pKa (Strongest Basic)	-2.6	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	4	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	80.92 Å²	ChemAxon
Rotatable Bond Count	6	ChemAxon
Refractivity	91.57 m³·mol⁻¹	ChemAxon
Polarizability	35.17 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

C00015842

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

101594595

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Not Available

Showing NP-Card for Perrottetin C (NP0061355)

MOL for NP0061355 (Perrottetin C)

3D MOL for NP0061355 (Perrottetin C)

3D SDF for NP0061355 (Perrottetin C)

3D-SDF for NP0061355 (Perrottetin C)

PDB for NP0061355 (Perrottetin C)

3D PDB for NP0061355 (Perrottetin C)

SMILES for NP0061355 (Perrottetin C)

INCHI for NP0061355 (Perrottetin C)

Structure for NP0061355 (Perrottetin C)

3D Structure for NP0061355 (Perrottetin C)