NP-MRD: Showing NP-Card for Isomarchantin C (NP0061316)

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Record Information

Version

2.0

Created at

2022-04-28 06:09:19 UTC

Updated at

2022-04-28 06:09:19 UTC

NP-MRD ID

NP0061316

Secondary Accession Numbers

None

Natural Product Identification

Common Name

Isomarchantin C

Description

Isomarchantin C belongs to the class of organic compounds known as lignans, neolignans and related compounds. These are plant products of low molecular weight formed primarily from oxidative coupling of two p-propylphenol moieties. They can also be described as micromolecules with two phenylpropanoid units coupled together. They can be attached in various manners, like C5-C5', C8-C8'. Most known natural lignans are oxidized at C9 and C9´ and, based upon the way in which oxygen is incorporated into the skeleton and on the cyclization patterns, a wide range of lignans of very different structural types can be formed. Isomarchantin C is found in Bryopteris filicina, Dumortiera hirsuta, Marchantia palmata and Marchantia polymorpha. Isomarchantin C is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004231522062D          

 32 36  0  0  0  0            999 V2000
    9.3538    4.2352    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.8441    3.5865    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.1695    2.8192    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.6539    2.1651    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8203    2.2637    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.2956    1.6026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.6095    1.1237    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7887    0.9625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0734    0.1882    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5451   -0.4455    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7322   -0.3049    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4475    0.4695    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6346    0.6101    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.9758    1.1032    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2488    1.5718    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.7212    2.2516    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8852    2.1646    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3714    2.8181    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6935    3.5870    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5200    3.7340    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8594    4.5292    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3986    5.1982    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2216    5.4421    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.8309    6.0256    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.6384    5.8001    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8741    4.9904    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.4888    4.3956    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.0153    3.7222    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.5242    3.0449    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2588    4.4252    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4630    4.6444    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0070    3.0464    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  3  4  1  0  0  0  0
  4  5  2  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  2  0  0  0  0
  9 10  1  0  0  0  0
 10 11  2  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 12 14  2  0  0  0  0
  8 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  2  0  0  0  0
 17 18  1  0  0  0  0
 18 19  2  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  2  0  0  0  0
 24 25  1  0  0  0  0
 25 26  2  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
  2 28  1  0  0  0  0
 28 29  2  0  0  0  0
  5 29  1  0  0  0  0
 26 30  1  0  0  0  0
 30 31  2  0  0  0  0
 23 31  1  0  0  0  0
 20 32  2  0  0  0  0
 16 32  1  0  0  0  0
M  END

     RDKit          3D

 56 60  0  0  0  0  0  0  0  0999 V2000
   -1.2513    5.2570   -1.9719 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3911    4.1435   -2.0026 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9545    4.4917   -1.9928 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8304    3.4313   -2.0207 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4239    2.0850   -2.0620 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0832    1.7621   -2.0839 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7922    2.8274   -2.0412 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2242    2.7492   -1.9985 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7675    1.8434   -0.9519 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0042    2.2413    0.3171 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4773    1.3569    1.3296 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7156    0.0227    1.0225 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4937   -0.4000   -0.2765 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0218    0.5351   -1.2332 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0491   -0.9859    2.1328 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7498   -1.4830    2.8008 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7534   -1.9247    1.8025 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3432   -2.9907    1.0709 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7245   -3.6760    0.0705 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4553   -3.2647   -0.1978 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2223   -2.2091    0.4811 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4838   -1.5654    1.4820 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4794   -2.0424   -0.0073 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.7854   -1.7256    0.1992 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7723   -2.6182    0.6106 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4558   -3.9764    0.8449 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0940   -2.3233    0.8265 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4998   -1.0296    0.6213 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5651   -0.1170    0.2150 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2418   -0.4056   -0.0022 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4119    0.7098   -0.4254 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6185    1.1937   -1.8787 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2430    5.0723   -1.9791 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2791    5.5167   -1.9658 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.8933    3.7240   -2.0136 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2851    0.6915   -2.2456 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9021    3.2695    0.7706 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5912    1.9428    2.2847 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6283   -1.4062   -0.7763 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9316   -0.0037   -2.2162 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6497   -1.8083    1.7200 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6114   -0.5855    2.9996 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5228   -0.7828    3.5847 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1704   -2.3711    3.3835 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3685   -3.3218    1.2925 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2025   -4.4907   -0.4766 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.0434   -3.8237   -1.0218 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.0549   -0.6921    2.0217 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.4998   -4.2631    0.7029 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.8036   -3.0991    1.1533 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.5259   -0.7790    0.7869 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.9222    0.9217    0.0561 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.5905    1.6234    0.1860 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.3090    0.5237   -0.2532 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.8631    0.4468   -2.5878 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.5814    1.7822   -1.7752 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  2  0
  3  4  1  0
  4  5  2  0
  5 32  1  0
 32 31  1  0
 31 30  1  0
 30 29  2  0
 29 28  1  0
 28 27  2  0
 27 25  1  0
 25 26  1  0
 25 24  2  0
 24 23  1  0
 23 21  1  0
 21 20  2  0
 20 19  1  0
 19 18  2  0
 18 17  1  0
 17 16  1  0
 16 15  1  0
 15 12  1  0
 12 11  2  0
 11 10  1  0
 10  9  2  0
  9  8  1  0
  8  7  1  0
  7  6  2  0
  9 14  1  0
 14 13  2  0
 17 22  2  0
  7  2  1  0
  6  5  1  0
 24 30  1  0
 22 21  1  0
 13 12  1  0
  1 33  1  0
  3 34  1  0
  4 35  1  0
 32 55  1  0
 32 56  1  0
 31 53  1  0
 31 54  1  0
 29 52  1  0
 28 51  1  0
 27 50  1  0
 26 49  1  0
 20 47  1  0
 19 46  1  0
 18 45  1  0
 16 43  1  0
 16 44  1  0
 15 41  1  0
 15 42  1  0
 11 38  1  0
 10 37  1  0
  6 36  1  0
 14 40  1  0
 13 39  1  0
 22 48  1  0
M  END


  Mrv1533004231522062D          

 32 36  0  0  0  0            999 V2000
    9.3538    4.2352    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.8441    3.5865    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.1695    2.8192    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.6539    2.1651    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8203    2.2637    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.2956    1.6026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.6095    1.1237    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7887    0.9625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0734    0.1882    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5451   -0.4455    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7322   -0.3049    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4475    0.4695    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6346    0.6101    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.9758    1.1032    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2488    1.5718    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.7212    2.2516    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8852    2.1646    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3714    2.8181    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6935    3.5870    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5200    3.7340    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8594    4.5292    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3986    5.1982    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2216    5.4421    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.8309    6.0256    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.6384    5.8001    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8741    4.9904    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.4888    4.3956    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.0153    3.7222    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.5242    3.0449    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2588    4.4252    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4630    4.6444    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0070    3.0464    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  3  4  1  0  0  0  0
  4  5  2  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  2  0  0  0  0
  9 10  1  0  0  0  0
 10 11  2  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 12 14  2  0  0  0  0
  8 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  2  0  0  0  0
 17 18  1  0  0  0  0
 18 19  2  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  2  0  0  0  0
 24 25  1  0  0  0  0
 25 26  2  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
  2 28  1  0  0  0  0
 28 29  2  0  0  0  0
  5 29  1  0  0  0  0
 26 30  1  0  0  0  0
 30 31  2  0  0  0  0
 23 31  1  0  0  0  0
 20 32  2  0  0  0  0
 16 32  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0061316

> <DATABASE_NAME>
NP-MRD

> <SMILES>
OC1=CC=C2CCC3=CC=CC(O)=C3OC3=CC=CC(CCC4=CC=C(OC1=C2)C=C4)=C3

> <INCHI_IDENTIFIER>
InChI=1S/C28H24O4/c29-25-16-12-21-9-13-22-4-2-6-26(30)28(22)32-24-5-1-3-20(17-24)8-7-19-10-14-23(15-11-19)31-27(25)18-21/h1-6,10-12,14-18,29-30H,7-9,13H2

> <INCHI_KEY>
NTXTVDLVUWOMKO-UHFFFAOYSA-N

> <FORMULA>
C28H24O4

> <MOLECULAR_WEIGHT>
424.496

> <EXACT_MASS>
424.167459253

> <JCHEM_ACCEPTOR_COUNT>
2

> <JCHEM_ATOM_COUNT>
56

> <JCHEM_AVERAGE_POLARIZABILITY>
45.18355336196525

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
2

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
2,16-dioxapentacyclo[22.2.2.1³,⁷.1¹⁷,²¹.0¹⁰,¹⁵]triaconta-1(26),3(30),4,6,10,12,14,17,19,21(29),24,27-dodecaene-4,14-diol

> <ALOGPS_LOGP>
6.40

> <JCHEM_LOGP>
7.466169106666667

> <ALOGPS_LOGS>
-5.88

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
8.973715271418808

> <JCHEM_PKA_STRONGEST_ACIDIC>
8.354209797179193

> <JCHEM_PKA_STRONGEST_BASIC>
-3.424901916698151

> <JCHEM_POLAR_SURFACE_AREA>
58.92

> <JCHEM_REFRACTIVITY>
125.11980000000001

> <JCHEM_ROTATABLE_BOND_COUNT>
0

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
5.64e-04 g/l

> <JCHEM_TRADITIONAL_IUPAC>
2,16-dioxapentacyclo[22.2.2.1³,⁷.1¹⁷,²¹.0¹⁰,¹⁵]triaconta-1(26),3(30),4,6,10,12,14,17,19,21(29),24,27-dodecaene-4,14-diol

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 23-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   23-APR-15         0                                  
HETATM    1  O   UNK     0      17.460   7.906   0.000  0.00  0.00           O+0
HETATM    2  C   UNK     0      16.509   6.695   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      17.116   5.263   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      16.154   4.042   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      14.598   4.226   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      13.618   2.992   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      12.338   2.098   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      10.806   1.797   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      11.337   0.351   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      10.351  -0.832   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       8.833  -0.569   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       8.302   0.876   0.000  0.00  0.00           C+0
HETATM   13  O   UNK     0       6.785   1.139   0.000  0.00  0.00           O+0
HETATM   14  C   UNK     0       9.288   2.059   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0       7.931   2.934   0.000  0.00  0.00           O+0
HETATM   16  C   UNK     0       6.946   4.203   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       5.386   4.041   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       4.427   5.260   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       5.028   6.696   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       6.571   6.970   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       7.204   8.455   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       8.211   9.703   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       9.747  10.159   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      10.884  11.248   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0      12.392  10.827   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0      12.832   9.315   0.000  0.00  0.00           C+0
HETATM   27  O   UNK     0      13.979   8.205   0.000  0.00  0.00           O+0
HETATM   28  C   UNK     0      14.962   6.948   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0      14.045   5.684   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0      11.683   8.260   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0      10.198   8.669   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       7.480   5.687   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3   28                                                  
CONECT    3    2    4                                                       
CONECT    4    3    5                                                       
CONECT    5    4    6   29                                                  
CONECT    6    5    7                                                       
CONECT    7    6    8                                                       
CONECT    8    7    9   14                                                  
CONECT    9    8   10                                                       
CONECT   10    9   11                                                       
CONECT   11   10   12                                                       
CONECT   12   11   13   14                                                  
CONECT   13   12                                                            
CONECT   14   12    8   15                                                  
CONECT   15   14   16                                                       
CONECT   16   15   17   32                                                  
CONECT   17   16   18                                                       
CONECT   18   17   19                                                       
CONECT   19   18   20                                                       
CONECT   20   19   21   32                                                  
CONECT   21   20   22                                                       
CONECT   22   21   23                                                       
CONECT   23   22   24   31                                                  
CONECT   24   23   25                                                       
CONECT   25   24   26                                                       
CONECT   26   25   27   30                                                  
CONECT   27   26   28                                                       
CONECT   28   27    2   29                                                  
CONECT   29   28    5                                                       
CONECT   30   26   31                                                       
CONECT   31   30   23                                                       
CONECT   32   20   16                                                       
MASTER        0    0    0    0    0    0    0    0   32    0   72    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₈H₂₄O₄

Average Mass

424.4960 Da

Monoisotopic Mass

424.16746 Da

IUPAC Name

2,16-dioxapentacyclo[22.2.2.1³,⁷.1¹⁷,²¹.0¹⁰,¹⁵]triaconta-1(26),3(30),4,6,10,12,14,17,19,21(29),24,27-dodecaene-4,14-diol

Traditional Name

2,16-dioxapentacyclo[22.2.2.1³,⁷.1¹⁷,²¹.0¹⁰,¹⁵]triaconta-1(26),3(30),4,6,10,12,14,17,19,21(29),24,27-dodecaene-4,14-diol

CAS Registry Number

Not Available

SMILES

OC1=CC=C2CCC3=CC=CC(O)=C3OC3=CC=CC(CCC4=CC=C(OC1=C2)C=C4)=C3

InChI Identifier

InChI=1S/C28H24O4/c29-25-16-12-21-9-13-22-4-2-6-26(30)28(22)32-24-5-1-3-20(17-24)8-7-19-10-14-23(15-11-19)31-27(25)18-21/h1-6,10-12,14-18,29-30H,7-9,13H2

InChI Key

NTXTVDLVUWOMKO-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Bryopteris filicina	LOTUS Database	35616633
Dumortiera hirsuta	LOTUS Database	35616633
Marchantia palmata	Plant	KNApSAcK
Marchantia polymorpha	Plant	KNApSAcK

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as lignans, neolignans and related compounds. These are plant products of low molecular weight formed primarily from oxidative coupling of two p-propylphenol moieties. They can also be described as micromolecules with two phenylpropanoid units coupled together. They can be attached in various manners, like C5-C5', C8-C8'. Most known natural lignans are oxidized at C9 and C9´ and, based upon the way in which oxygen is incorporated into the skeleton and on the cyclization patterns, a wide range of lignans of very different structural types can be formed.

Kingdom

Organic compounds

Super Class

Lignans, neolignans and related compounds

Class

Not Available

Sub Class

Not Available

Direct Parent

Lignans, neolignans and related compounds

Alternative Parents

Substituents

Oxyneolignan skeleton
Diaryl ether
1-hydroxy-4-unsubstituted benzenoid
1-hydroxy-2-unsubstituted benzenoid
Phenol
Benzenoid
Oxacycle
Organoheterocyclic compound
Ether
Organic oxygen compound
Hydrocarbon derivative
Organooxygen compound
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	6.4	ALOGPS
logP	7.47	ChemAxon
logS	-5.9	ALOGPS
pKa (Strongest Acidic)	8.35	ChemAxon
pKa (Strongest Basic)	-3.4	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	2	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	58.92 Å²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	125.12 m³·mol⁻¹	ChemAxon
Polarizability	45.18 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

13831039

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Not Available

Showing NP-Card for Isomarchantin C (NP0061316)

MOL for NP0061316 (Isomarchantin C)

3D MOL for NP0061316 (Isomarchantin C)

3D SDF for NP0061316 (Isomarchantin C)

3D-SDF for NP0061316 (Isomarchantin C)

PDB for NP0061316 (Isomarchantin C)

3D PDB for NP0061316 (Isomarchantin C)

SMILES for NP0061316 (Isomarchantin C)

INCHI for NP0061316 (Isomarchantin C)

Structure for NP0061316 (Isomarchantin C)

3D Structure for NP0061316 (Isomarchantin C)