NP-MRD: Showing NP-Card for 3,3,6-Trimethyl-5-heptene-1,2,4-triol (NP0057299)

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Record Information

Version

2.0

Created at

2022-04-28 02:46:45 UTC

Updated at

2022-04-28 02:46:45 UTC

NP-MRD ID

NP0057299

Secondary Accession Numbers

None

Natural Product Identification

Common Name

3,3,6-Trimethyl-5-heptene-1,2,4-triol

Description

(2R,4S)-1,4-bis(acetyloxy)-3,3,6-trimethylhept-5-en-2-yl acetate belongs to the class of organic compounds known as tricarboxylic acids and derivatives. These are carboxylic acids containing exactly three carboxyl groups. 3,3,6-Trimethyl-5-heptene-1,2,4-triol is found in Calea oxylepis. Based on a literature review very few articles have been published on (2R,4S)-1,4-bis(acetyloxy)-3,3,6-trimethylhept-5-en-2-yl acetate.

Structure

MOL 3D MOL SDF PDB SMILES InChI

     RDKit          3D

 48 47  0  0  0  0  0  0  0  0999 V2000
    4.2462   -1.2334   -3.4691 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0628   -0.7306   -2.0602 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0771   -0.6692   -1.3105 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8066   -0.3480   -1.6107 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6534    0.1128   -0.3111 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2452    0.4954    0.0545 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.3101    0.9329    1.3973 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.9779    2.2520    1.6591 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0170    2.7987    3.0417 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6255    3.0644    0.7557 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.2922   -0.6520   -0.1327 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.4161   -1.1080   -1.5688 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7013   -1.8316    0.7368 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1310   -0.3171    0.2203 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.7198    0.7558   -0.5964 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8769    0.6094   -1.2326 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6340   -0.6667   -1.1417 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4558    1.7073   -2.0544 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2598   -0.0849    1.6189 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9568   -0.8576    2.4858 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0153   -0.5078    3.9207 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5498   -1.8639    2.0769 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.2167   -2.3550   -3.3726 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.4061   -0.8488   -4.0449 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.2343   -0.9321   -3.8210 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.0789   -0.6135    0.4131 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2867    1.0368   -0.2012 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.9156    1.3207   -0.6059 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1435    3.4557    3.1626 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.9877    1.9197    3.7334 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9765    3.3552    3.1984 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1182   -1.9551   -1.6944 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5711   -0.2822   -2.2792 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5915   -1.5412   -1.8429 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.7155   -2.1708    0.5444 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5897   -1.6047    1.8056 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.0112   -2.6769    0.4516 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7265   -1.2368    0.0420 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2535    1.7363   -0.7364 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9673   -1.4661   -1.5528 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9171   -0.9044   -0.0930 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5755   -0.5889   -1.6948 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9823    2.6979   -1.8154 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2731    1.4773   -3.1371 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5565    1.7309   -1.8830 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9286    0.5602    4.1295 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0241   -0.8487    4.2955 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2878   -1.1235    4.5195 H   0  0  0  0  0  0  0  0  0  0  0  0
 17 16  1  0
 16 18  1  0
 16 15  2  3
 15 14  1  0
 14 19  1  0
 19 20  1  0
 20 21  1  0
 20 22  2  0
 14 11  1  0
 11 12  1  6
 11 13  1  0
 11  6  1  0
  6  5  1  0
  5  4  1  0
  4  2  1  0
  2  1  1  0
  2  3  2  0
  6  7  1  0
  7  8  1  0
  8  9  1  0
  8 10  2  0
 17 40  1  0
 17 41  1  0
 17 42  1  0
 18 43  1  0
 18 44  1  0
 18 45  1  0
 15 39  1  0
 14 38  1  6
 21 46  1  0
 21 47  1  0
 21 48  1  0
 12 32  1  0
 12 33  1  0
 12 34  1  0
 13 35  1  0
 13 36  1  0
 13 37  1  0
  6 28  1  6
  5 26  1  0
  5 27  1  0
  1 23  1  0
  1 24  1  0
  1 25  1  0
  9 29  1  0
  9 30  1  0
  9 31  1  0
M  END


  Mrv1652304282204462D          

 22 21  0  0  1  0            999 V2000
    3.9039    1.4289    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1895    1.8414    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.4750    1.4289    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7605    1.0164    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.0461    1.4289    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0461    2.2539    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3316    2.6664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7605    2.6664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7605    0.1914    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0461   -0.2211    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3316    0.1914    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0461   -1.0461    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8875    0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0625    2.1434    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1895    2.6664    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.9039    3.0789    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9039    3.9039    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.6184    2.6664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6184    1.8414    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.3329    1.4289    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0474    1.8414    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.3329    0.6039    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  6  8  1  0  0  0  0
  4  9  1  1  0  0  0
  9 10  1  0  0  0  0
 10 11  2  0  0  0  0
 10 12  1  0  0  0  0
  3 13  1  0  0  0  0
  3 14  1  0  0  0  0
  2 15  1  1  0  0  0
 15 16  1  0  0  0  0
 16 17  2  0  0  0  0
 16 18  1  0  0  0  0
  1 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  2  0  0  0  0
 20 22  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0057299

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(C)=C[C@H](OC(C)=O)C(C)(C)[C@H](COC(C)=O)OC(C)=O

> <INCHI_IDENTIFIER>
InChI=1S/C16H26O6/c1-10(2)8-14(21-12(4)18)16(6,7)15(22-13(5)19)9-20-11(3)17/h8,14-15H,9H2,1-7H3/t14-,15-/m0/s1

> <INCHI_KEY>
YCPRKSWWEMVOBC-GJZGRUSLSA-N

> <FORMULA>
C16H26O6

> <MOLECULAR_WEIGHT>
314.378

> <EXACT_MASS>
314.172938557

> <JCHEM_ACCEPTOR_COUNT>
3

> <JCHEM_ATOM_COUNT>
48

> <JCHEM_AVERAGE_POLARIZABILITY>
33.41732242167053

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
(2R,4S)-1,4-bis(acetyloxy)-3,3,6-trimethylhept-5-en-2-yl acetate

> <ALOGPS_LOGP>
2.44

> <JCHEM_LOGP>
1.9370102493333334

> <ALOGPS_LOGS>
-3.23

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
0

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_BASIC>
-6.530623905442864

> <JCHEM_POLAR_SURFACE_AREA>
78.9

> <JCHEM_REFRACTIVITY>
80.3837

> <JCHEM_ROTATABLE_BOND_COUNT>
10

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
1.87e-01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(2R,4S)-1,4-bis(acetyloxy)-3,3,6-trimethylhept-5-en-2-yl acetate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 28-APR-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   28-APR-22         0                                  
HETATM    1  C   UNK     0       7.287   2.667   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       5.954   3.437   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       4.620   2.667   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       3.286   1.897   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       1.953   2.667   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       1.953   4.207   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       0.619   4.977   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       3.286   4.977   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0       3.286   0.357   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0       1.953  -0.413   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0       0.619   0.357   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0       1.953  -1.953   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       5.390   1.334   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       3.850   4.001   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0       5.954   4.977   0.000  0.00  0.00           O+0
HETATM   16  C   UNK     0       7.287   5.747   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0       7.287   7.287   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0       8.621   4.977   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0       8.621   3.437   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0       9.955   2.667   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0      11.288   3.437   0.000  0.00  0.00           O+0
HETATM   22  C   UNK     0       9.955   1.127   0.000  0.00  0.00           C+0
CONECT    1    2   19                                                       
CONECT    2    1    3   15                                                  
CONECT    3    2    4   13   14                                             
CONECT    4    3    5    9                                                  
CONECT    5    4    6                                                       
CONECT    6    5    7    8                                                  
CONECT    7    6                                                            
CONECT    8    6                                                            
CONECT    9    4   10                                                       
CONECT   10    9   11   12                                                  
CONECT   11   10                                                            
CONECT   12   10                                                            
CONECT   13    3                                                            
CONECT   14    3                                                            
CONECT   15    2   16                                                       
CONECT   16   15   17   18                                                  
CONECT   17   16                                                            
CONECT   18   16                                                            
CONECT   19    1   20                                                       
CONECT   20   19   21   22                                                  
CONECT   21   20                                                            
CONECT   22   20                                                            
MASTER        0    0    0    0    0    0    0    0   22    0   42    0
END

View in JSmol

Synonyms

Value	Source
(2R,4S)-1,4-Bis(acetyloxy)-3,3,6-trimethylhept-5-en-2-yl acetic acid	Generator

Chemical Formula

C₁₆H₂₆O₆

Average Mass

314.3780 Da

Monoisotopic Mass

314.17294 Da

IUPAC Name

(2R,4S)-1,4-bis(acetyloxy)-3,3,6-trimethylhept-5-en-2-yl acetate

Traditional Name

(2R,4S)-1,4-bis(acetyloxy)-3,3,6-trimethylhept-5-en-2-yl acetate

CAS Registry Number

Not Available

SMILES

CC(C)=C[C@H](OC(C)=O)C(C)(C)[C@H](COC(C)=O)OC(C)=O

InChI Identifier

InChI=1S/C16H26O6/c1-10(2)8-14(21-12(4)18)16(6,7)15(22-13(5)19)9-20-11(3)17/h8,14-15H,9H2,1-7H3/t14-,15-/m0/s1

InChI Key

YCPRKSWWEMVOBC-GJZGRUSLSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Calea oxylepis	Plant	KNApSAcK

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as tricarboxylic acids and derivatives. These are carboxylic acids containing exactly three carboxyl groups.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Carboxylic acids and derivatives

Sub Class

Tricarboxylic acids and derivatives

Direct Parent

Tricarboxylic acids and derivatives

Alternative Parents

Substituents

Tricarboxylic acid or derivatives
Carboxylic acid ester
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	2.44	ALOGPS
logP	1.94	ChemAxon
logS	-3.2	ALOGPS
pKa (Strongest Basic)	-6.5	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	3	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	78.9 Å²	ChemAxon
Rotatable Bond Count	10	ChemAxon
Refractivity	80.38 m³·mol⁻¹	ChemAxon
Polarizability	33.42 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

162891567

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Not Available

Showing NP-Card for 3,3,6-Trimethyl-5-heptene-1,2,4-triol (NP0057299)

MOL for NP0057299 (3,3,6-Trimethyl-5-heptene-1,2,4-triol)

3D MOL for NP0057299 (3,3,6-Trimethyl-5-heptene-1,2,4-triol)

3D SDF for NP0057299 (3,3,6-Trimethyl-5-heptene-1,2,4-triol)

3D-SDF for NP0057299 (3,3,6-Trimethyl-5-heptene-1,2,4-triol)

PDB for NP0057299 (3,3,6-Trimethyl-5-heptene-1,2,4-triol)

3D PDB for NP0057299 (3,3,6-Trimethyl-5-heptene-1,2,4-triol)

SMILES for NP0057299 (3,3,6-Trimethyl-5-heptene-1,2,4-triol)

INCHI for NP0057299 (3,3,6-Trimethyl-5-heptene-1,2,4-triol)

Structure for NP0057299 (3,3,6-Trimethyl-5-heptene-1,2,4-triol)

3D Structure for NP0057299 (3,3,6-Trimethyl-5-heptene-1,2,4-triol)