NP-MRD: Showing NP-Card for (+)-Matrine (NP0051280)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-04-27 22:39:47 UTC

Updated at

2022-04-27 22:39:47 UTC

NP-MRD ID

NP0051280

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(+)-Matrine

Description

Matrine belongs to the class of organic compounds known as matrine alkaloids. These are lupin alkaloids with a structure based on the matrine skeleton, a four-ring skeleton that based on a saturated dipyrido[2,1-f:3',2',1'-Ij][1,6]naphthyridin-10-one skeleton. Matrine is a very strong basic compound (based on its pKa). Matrine possesses strong antitumor activities in vitro and in vivo. Matrine is an alkaloid found in plants from the Sophora genus. Matrine is a potentially toxic compound. Inhibition of cell proliferation and induction of apoptosis are the likely mechanisms responsible for matrine's antitumor activities. Morphological observation revealed degenerative changes of the nerve cells in the brain tissue of the mice. (+)-Matrine is found in Ammothamnus lehmannii, Corydalis yanhusuo , Daphniphyllum oldhami, Euchresta formosana, Euchresta horsfeldii, Goebelia pachycarpa, Gymnospermium albertii, Leontice albertii, Sophora alopecuroides, Sophora chrysophylla, Sophora davidii, Sophora flavescens , Sophora griffithii Stocks., Sophora japonica L. , Sophora jaubertii, Sophora macrocarpa, Sophora macrophylla, Sophora microphylla, Sophora pachycarpa, Sophora pachycarpa Schrenk., Sophora subprostate, Sophora subprostrata, Sophora tetraptera , Sophora tomentosa, Sophora tonkinensis, Sophora viciifolia, Sophorae flavescentis, Styphnolobium japonicum and Vexibia pachycarpa. The nervous system is the main target organ by the toxicity of matrine.

Structure

MOL 3D MOL SDF PDB SMILES InChI

     RDKit          3D

 42 45  0  0  0  0  0  0  0  0999 V2000
    2.6172    2.7581   -1.2209 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.7055    1.6181   -0.7133 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9967    0.8962   -0.8192 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8863   -0.5042   -0.2387 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5333   -1.1139   -0.5414 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5153   -0.3406    0.2667 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.1506   -0.9207    0.2139 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.4274   -1.2106    1.5782 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6009   -2.1473    1.3695 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1085   -2.0554   -0.0257 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0646   -0.7657   -0.6156 N   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2389   -0.0398   -0.4527 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1746    1.4401   -0.5883 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0069    1.8641    0.3145 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7720    1.3321   -0.4250 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.4157    1.8390    0.3209 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5753    1.0682   -0.0629 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8141   -0.1267   -0.6580 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.2723    0.8333   -1.8880 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.7609    1.4486   -0.2366 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.7251   -1.1188   -0.5686 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.9345   -0.3869    0.8742 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.5507   -2.1458   -0.1469 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.3060   -1.1391   -1.6112 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.8672   -0.4116    1.3382 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2336   -1.9275   -0.2930 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7011   -0.3129    2.1452 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.3423   -1.7839    2.1307 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3503   -1.8919    2.1424 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3116   -3.2054    1.5602 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1834   -2.3928   -0.0287 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5753   -2.7944   -0.6781 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6680   -0.2569    0.5697 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0415   -0.4015   -1.1543 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9127    1.7253   -1.6261 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1024    1.9016   -0.2256 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1228    1.4274    1.3029 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8994    2.9684    0.3041 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7966    1.9001   -1.4037 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2754    1.7539    1.4210 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.6227    2.9129    0.0791 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4138   -0.2929   -1.7087 H   0  0  0  0  0  0  0  0  0  0  0  0
 15 14  1  0
 14 13  1  0
 13 12  1  0
 12 11  1  0
 11 10  1  0
 10  9  1  0
  9  8  1  0
  8  7  1  0
  7  6  1  0
  6  5  1  0
  5  4  1  0
  4  3  1  0
  3  2  1  0
  2  1  2  0
  2 17  1  0
 17 16  1  0
  7 18  1  0
 16 15  1  0
 18 15  1  0
 18 11  1  0
 17  6  1  0
 15 39  1  6
 14 37  1  0
 14 38  1  0
 13 35  1  0
 13 36  1  0
 12 33  1  0
 12 34  1  0
 10 31  1  0
 10 32  1  0
  9 29  1  0
  9 30  1  0
  8 27  1  0
  8 28  1  0
  7 26  1  6
  6 25  1  1
  5 23  1  0
  5 24  1  0
  4 21  1  0
  4 22  1  0
  3 19  1  0
  3 20  1  0
 16 40  1  0
 16 41  1  0
 18 42  1  6
M  END


  Mrv0541 08291401032D          

 22 25  0  0  1  0            999 V2000
    5.0013   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.8579   -1.6500    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.5724   -1.2375    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.2868    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.4289   -1.6500    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    0.4125    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -2.0625    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -0.8250    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -0.8250    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
  4  2  1  0  0  0  0
  5  3  1  0  0  0  0
  6  1  1  0  0  0  0
  7  1  1  0  0  0  0
  8  2  1  0  0  0  0
  9  3  1  0  0  0  0
 11  4  1  0  0  0  0
 11 10  1  0  0  0  0
 12  5  1  0  0  0  0
 13  6  1  0  0  0  0
 13 12  1  0  0  0  0
 14  7  1  0  0  0  0
 15 11  1  0  0  0  0
 15 12  1  0  0  0  0
 16  8  1  0  0  0  0
 16  9  1  0  0  0  0
 16 15  1  0  0  0  0
 17 10  1  0  0  0  0
 17 13  1  0  0  0  0
 17 14  1  0  0  0  0
 18 14  2  0  0  0  0
 11 19  1  6  0  0  0
 12 20  1  6  0  0  0
 13 21  1  1  0  0  0
 15 22  1  6  0  0  0
M  END
> <DATABASE_ID>
NP0051280

> <DATABASE_NAME>
NP-MRD

> <SMILES>
[H][C@]12CCCN3CCC[C@]([H])([C@@]4([H])CCCC(=O)N4C1)[C@]23[H]

> <INCHI_IDENTIFIER>
InChI=1S/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-/m0/s1

> <INCHI_KEY>
ZSBXGIUJOOQZMP-JLNYLFASSA-N

> <FORMULA>
C15H24N2O

> <MOLECULAR_WEIGHT>
248.3639

> <EXACT_MASS>
248.1888634

> <JCHEM_ACCEPTOR_COUNT>
2

> <JCHEM_ATOM_COUNT>
42

> <JCHEM_AVERAGE_POLARIZABILITY>
28.688682598674603

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
(1R,2R,9S,17S)-7,13-diazatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadecan-6-one

> <ALOGPS_LOGP>
1.92

> <JCHEM_LOGP>
1.0759273119999997

> <ALOGPS_LOGS>
-1.60

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
1

> <JCHEM_PKA_STRONGEST_BASIC>
9.75220211509645

> <JCHEM_POLAR_SURFACE_AREA>
23.55

> <JCHEM_REFRACTIVITY>
71.4485

> <JCHEM_ROTATABLE_BOND_COUNT>
0

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
6.24e+00 g/l

> <JCHEM_TRADITIONAL_IUPAC>
matrine

> <JCHEM_VEBER_RULE>
1

$$$$

HEADER    PROTEIN                                 29-AUG-14   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   29-AUG-14         0                                  
HETATM    1  C   UNK     0       9.336  -2.310   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       1.334  -0.770   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       4.001  -5.390   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       2.667   0.000   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       5.335  -4.620   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       8.002  -3.080   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       9.336  -0.770   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       1.334  -2.310   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       2.667  -4.620   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       5.335   0.000   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       4.001  -0.770   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       5.335  -3.080   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       6.668  -2.310   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       8.002   0.000   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       4.001  -2.310   0.000  0.00  0.00           C+0
HETATM   16  N   UNK     0       2.667  -3.080   0.000  0.00  0.00           N+0
HETATM   17  N   UNK     0       6.668  -0.770   0.000  0.00  0.00           N+0
HETATM   18  O   UNK     0       8.002   1.540   0.000  0.00  0.00           O+0
HETATM   19  H   UNK     0       4.001   0.770   0.000  0.00  0.00           H+0
HETATM   20  H   UNK     0       6.668  -3.850   0.000  0.00  0.00           H+0
HETATM   21  H   UNK     0       8.002  -1.540   0.000  0.00  0.00           H+0
HETATM   22  H   UNK     0       5.335  -1.540   0.000  0.00  0.00           H+0
CONECT    1    6    7                                                       
CONECT    2    4    8                                                       
CONECT    3    5    9                                                       
CONECT    4    2   11                                                       
CONECT    5    3   12                                                       
CONECT    6    1   13                                                       
CONECT    7    1   14                                                       
CONECT    8    2   16                                                       
CONECT    9    3   16                                                       
CONECT   10   11   17                                                       
CONECT   11    4   10   15   19                                             
CONECT   12    5   13   15   20                                             
CONECT   13    6   12   17   21                                             
CONECT   14    7   17   18                                                  
CONECT   15   11   12   16   22                                             
CONECT   16    8    9   15                                                  
CONECT   17   10   13   14                                                  
CONECT   18   14                                                            
CONECT   19   11                                                            
CONECT   20   12                                                            
CONECT   21   13                                                            
CONECT   22   15                                                            
MASTER        0    0    0    0    0    0    0    0   22    0   50    0
END

View in JSmol

Synonyms

Value	Source
Sophoridine	MeSH
Matrine, (5beta)-isomer	MeSH

Chemical Formula

C₁₅H₂₄N₂O

Average Mass

248.3639 Da

Monoisotopic Mass

248.18886 Da

IUPAC Name

(1R,2R,9S,17S)-7,13-diazatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadecan-6-one

Traditional Name

matrine

CAS Registry Number

Not Available

SMILES

[H][C@]12CCCN3CCC[C@]([H])([C@@]4([H])CCCC(=O)N4C1)[C@]23[H]

InChI Identifier

InChI=1S/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-/m0/s1

InChI Key

ZSBXGIUJOOQZMP-JLNYLFASSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Ammothamnus lehmannii	LOTUS Database	35616633
Corydalis yanhusuo	Plant	KNApSAcK
Daphniphyllum oldhamii	Plant	KNApSAcK
Euchresta formosana	Plant	KNApSAcK
Euchresta horsfeldii	Plant	KNApSAcK
Goebelia pachycarpa	Plant	KNApSAcK
Gymnospermium albertii	LOTUS Database	35616633
Leontice albertii	Plant	KNApSAcK
Sophora alopecuroides	Plant	KNApSAcK
Sophora chrysophylla	Plant	KNApSAcK
Sophora davidii	Plant	KNApSAcK
Sophora flavescens	Plant	KNApSAcK
Sophora griffithii Stocks.	Plant	KNApSAcK
Sophora japonica L.	Plant	KNApSAcK
Sophora jaubertii	LOTUS Database	35616633
Sophora macrocarpa	LOTUS Database	35616633
Sophora macrophylla	Plant	KNApSAcK
Sophora microphylla	LOTUS Database	35616633
Sophora pachycarpa	LOTUS Database	35616633
Sophora pachycarpa Schrenk.	Plant	KNApSAcK
Sophora subprostate	Plant	KNApSAcK
Sophora subprostrata	Plant	KNApSAcK
Sophora tetraptera	Plant	KNApSAcK
Sophora tomentosa	LOTUS Database	35616633
Sophora tonkinensis	Plant	KNApSAcK
Sophora viciifolia	Plant	KNApSAcK
Sophorae flavescentis	-	KNApSAcK
Styphnolobium japonicum	LOTUS Database	35616633
Vexibia pachycarpa	Plant	KNApSAcK

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as matrine alkaloids. These are lupin alkaloids with a structure based on the matrine skeleton, a four-ring skeleton that based on a saturated dipyrido[2,1-f:3',2',1'-Ij][1,6]naphthyridin-10-one skeleton.

Kingdom

Organic compounds

Super Class

Alkaloids and derivatives

Class

Lupin alkaloids

Sub Class

Matrine alkaloids

Direct Parent

Matrine alkaloids

Alternative Parents

Substituents

Matrine
Quinolizidinone
Diazanaphthalene
Naphthyridine
Quinolizidine
Delta-lactam
Piperidinone
Piperidine
Tertiary carboxylic acid amide
Tertiary aliphatic amine
Tertiary amine
Amino acid or derivatives
Carboxamide group
Lactam
Organoheterocyclic compound
Azacycle
Carboxylic acid derivative
Hydrocarbon derivative
Organic oxygen compound
Organic nitrogen compound
Organonitrogen compound
Organooxygen compound
Amine
Carbonyl group
Organopnictogen compound
Organic oxide
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

alkaloid (CHEBI:6700 )
Alkaloids (C10774 )
Quinolizidine alkaloids (C10774 )

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	1.92	ALOGPS
logP	1.08	ChemAxon
logS	-1.6	ALOGPS
pKa (Strongest Basic)	9.75	ChemAxon
Physiological Charge	1	ChemAxon
Hydrogen Acceptor Count	2	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	23.55 Å²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	71.45 m³·mol⁻¹	ChemAxon
Polarizability	28.69 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	Yes	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

C00002227

Chemspider ID

Not Available

KEGG Compound ID

C10774

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Matrine

METLIN ID

Not Available

PubChem Compound

91466

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Not Available

Showing NP-Card for (+)-Matrine (NP0051280)

MOL for NP0051280 ((+)-Matrine)

3D MOL for NP0051280 ((+)-Matrine)

3D SDF for NP0051280 ((+)-Matrine)

3D-SDF for NP0051280 ((+)-Matrine)

PDB for NP0051280 ((+)-Matrine)

3D PDB for NP0051280 ((+)-Matrine)

SMILES for NP0051280 ((+)-Matrine)

INCHI for NP0051280 ((+)-Matrine)

Structure for NP0051280 ((+)-Matrine)

3D Structure for NP0051280 ((+)-Matrine)