| Description | Falcarindiol belongs to the class of organic compounds known as long-chain fatty alcohols. These are fatty alcohols that have an aliphatic tail of 13 to 21 carbon atoms. Falcarindiol is an extremely weak basic (essentially neutral) compound (based on its pKa). Falcarindiol is a bitter tasting compound. Outside of the human body, Falcarindiol is found, on average, in the highest concentration within wild carrots and carrots. Falcarindiol has also been detected, but not quantified in, several different foods, such as green vegetables, caraway, garden tomato (var.), Wild celeries, and parsley. This could make falcarindiol a potential biomarker for the consumption of these foods. Falcarindiol and other falcarindiol-type polyacetylenes are also found in many other plants of the family Apiaceae, including some commonly used seasonings such as dill and parsley. A variety of bioactivities have been reported so far for falcaridiol and the falcarindiol-type polyacetylenes, and because of potential health-promoting metabolic effects these compounds are studied as potential nutraceuticals. Falcarindiol is a polyacetylene found in carrot roots which has antifungal activity. Falcarindiol is the main compound responsible for bitterness in carrots. Falcarindiol is found in Foeniculum vulgare , Angelica acutiloba , Angelica biserrata, Angelica dahurica , Angelica furcijuga KITAGAWA, Angelica japonica, Angelica keiskei, Angelica pubescens, Angelica pubescens f.biserrta , Angelica sinensis , Anisotome pilifera, Anthriscus nitida, Anthriscus sylvestris, Aralia cordata , Bunium paucifolium, Chaerophyllum aureum, Chaerophyllum hirsutum, Cicuta virosa, Cladosporium fulvum, Crithmum maritimum , Cussonia arborea, Cussonia zimmermannii, Dendropanax arboreus, Eleutherococcus senticosus, Ferula linkii, Glehnia littoralis, Hansenia weberbaueriana, Schefflera taiwaniana, Heracleum candicans, Heracleum candicans WALL. , Heracleum moellendorffii, Heracleum yungningense, Heteromorpha arborescens, Laserpitium gallicum, Ligusticum multivittatum, Sinodielsia yunnanensis, Niphogeton ternata, Hansenia forbesii, Oenanthe fistulosa, Oenanthe javanica , Oplopanax horridus, Osmorhiza occidentalis, Peucedanum praeruptorum, Saposhnikovia divaricata, Schefflera digitata, Solanum lycopersicum , Solanum melongena and Thapsia villosa. It is the most-active among several polyynes with potential anticancer activity found in Devil's Club (Oplopanax horridus), a medicinal plant used by many indigenous peoples in Alaska and the Pacific Northwest. |
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| Structure | CCCCCCC\C=C/C(O)C#CC#CC(O)C=C InChI=1S/C17H24O2/c1-3-5-6-7-8-9-10-14-17(19)15-12-11-13-16(18)4-2/h4,10,14,16-19H,2-3,5-9H2,1H3/b14-10- |
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| InChI Identifier | InChI=1S/C17H24O2/c1-3-5-6-7-8-9-10-14-17(19)15-12-11-13-16(18)4-2/h4,10,14,16-19H,2-3,5-9H2,1H3/b14-10- |
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