NP-MRD: Showing NP-Card for Cerasidin (NP0045661)

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Record Information

Version

2.0

Created at

2022-03-17 19:33:35 UTC

Updated at

2022-03-17 19:33:35 UTC

NP-MRD ID

NP0045661

Secondary Accession Numbers

None

Natural Product Identification

Common Name

Cerasidin

Description

Cerasidin is found in Terminalia arjuna .

Structure

MOL SDF PDB SMILES InChI


  Mrv0541 02241212182D          

 25 26  0  0  0  0            999 V2000
   -3.9482    0.0295    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6627   -0.3830    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6627   -1.2080    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9482   -1.6206    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2337   -1.2080    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2337   -0.3830    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5193    0.0295    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5193   -1.6206    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8048   -1.2080    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0904   -1.6206    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3759   -1.2080    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3759   -0.3830    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3386    0.0295    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3386   -1.6206    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0530   -1.2080    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0530   -0.3830    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3772    0.0295    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0916   -0.3830    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9482   -2.4456    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5193   -2.4456    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3386   -2.4456    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0531   -2.8581    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7675    0.0295    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.4820   -0.3830    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8048   -0.3830    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  1  6  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  7  6  1  0  0  0  0
  5  6  2  0  0  0  0
  5  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 13 12  1  0  0  0  0
 11 12  2  0  0  0  0
 11 14  1  0  0  0  0
 13 16  2  0  0  0  0
 14 15  2  0  0  0  0
 15 16  1  0  0  0  0
  2 17  1  0  0  0  0
 17 18  1  0  0  0  0
  4 19  1  0  0  0  0
  8 20  2  0  0  0  0
 14 21  1  0  0  0  0
 21 22  1  0  0  0  0
 16 23  1  0  0  0  0
 23 24  1  0  0  0  0
  7 25  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0045661

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC1=CC=C(\C=C\C(=O)C2=C(OC)C=C(OC)C=C2O)C(OC)=C1

> <INCHI_IDENTIFIER>
InChI=1S/C19H20O6/c1-22-13-7-5-12(17(10-13)24-3)6-8-15(20)19-16(21)9-14(23-2)11-18(19)25-4/h5-11,21H,1-4H3/b8-6+

> <INCHI_KEY>
IAUDUEQNUVKNBT-SOFGYWHQSA-N

> <FORMULA>
C19H20O6

> <MOLECULAR_WEIGHT>
344.3585

> <EXACT_MASS>
344.125988372

> <JCHEM_ACCEPTOR_COUNT>
6

> <JCHEM_AVERAGE_POLARIZABILITY>
36.24085053798916

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
(2E)-3-(2,4-dimethoxyphenyl)-1-(2-hydroxy-4,6-dimethoxyphenyl)prop-2-en-1-one

> <ALOGPS_LOGP>
3.54

> <JCHEM_LOGP>
3.6060749246666663

> <ALOGPS_LOGS>
-4.34

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
16.619833934151988

> <JCHEM_PKA_STRONGEST_ACIDIC>
8.189281764302196

> <JCHEM_PKA_STRONGEST_BASIC>
-4.257566081638548

> <JCHEM_POLAR_SURFACE_AREA>
74.22

> <JCHEM_REFRACTIVITY>
94.71069999999997

> <JCHEM_ROTATABLE_BOND_COUNT>
7

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
1.59e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
cerasidin

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 24-FEB-12   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   24-FEB-12         0                                  
HETATM    1  C   UNK     0      -7.370   0.055   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -8.704  -0.715   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -8.704  -2.255   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -7.370  -3.025   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -6.036  -2.255   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -6.036  -0.715   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0      -4.703   0.055   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0      -4.703  -3.025   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      -3.369  -2.255   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      -2.035  -3.025   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0      -0.702  -2.255   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0      -0.702  -0.715   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       0.632   0.055   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       0.632  -3.025   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       1.966  -2.255   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       1.966  -0.715   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0     -10.037   0.055   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0     -11.371  -0.715   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0      -7.370  -4.565   0.000  0.00  0.00           O+0
HETATM   20  O   UNK     0      -4.703  -4.565   0.000  0.00  0.00           O+0
HETATM   21  O   UNK     0       0.632  -4.565   0.000  0.00  0.00           O+0
HETATM   22  C   UNK     0       1.966  -5.335   0.000  0.00  0.00           C+0
HETATM   23  O   UNK     0       3.299   0.055   0.000  0.00  0.00           O+0
HETATM   24  C   UNK     0       4.633  -0.715   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0      -3.369  -0.715   0.000  0.00  0.00           C+0
CONECT    1    2    6                                                       
CONECT    2    1    3   17                                                  
CONECT    3    2    4                                                       
CONECT    4    3    5   19                                                  
CONECT    5    4    6    8                                                  
CONECT    6    1    7    5                                                  
CONECT    7    6   25                                                       
CONECT    8    5    9   20                                                  
CONECT    9    8   10                                                       
CONECT   10    9   11                                                       
CONECT   11   10   12   14                                                  
CONECT   12   13   11                                                       
CONECT   13   12   16                                                       
CONECT   14   11   15   21                                                  
CONECT   15   14   16                                                       
CONECT   16   13   15   23                                                  
CONECT   17    2   18                                                       
CONECT   18   17                                                            
CONECT   19    4                                                            
CONECT   20    8                                                            
CONECT   21   14   22                                                       
CONECT   22   21                                                            
CONECT   23   16   24                                                       
CONECT   24   23                                                            
CONECT   25    7                                                            
MASTER        0    0    0    0    0    0    0    0   25    0   52    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₁₉H₂₀O₆

Average Mass

344.3585 Da

Monoisotopic Mass

344.12599 Da

IUPAC Name

(2E)-3-(2,4-dimethoxyphenyl)-1-(2-hydroxy-4,6-dimethoxyphenyl)prop-2-en-1-one

Traditional Name

cerasidin

CAS Registry Number

64200-22-2

SMILES

COC1=CC=C(\C=C\C(=O)C2=C(OC)C=C(OC)C=C2O)C(OC)=C1

InChI Identifier

InChI=1S/C19H20O6/c1-22-13-7-5-12(17(10-13)24-3)6-8-15(20)19-16(21)9-14(23-2)11-18(19)25-4/h5-11,21H,1-4H3/b8-6+

InChI Key

IAUDUEQNUVKNBT-SOFGYWHQSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Prunus cerasus	FooDB	Dr. Duke's Phytochemical and Ethnobotanical Databases
Terminalia arjuna	Plant	KNApSAcK

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as 2'-hydroxychalcones. These are organic compounds containing chalcone skeleton that carries a hydroxyl group at the 2'-position.

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Linear 1,3-diarylpropanoids

Sub Class

Chalcones and dihydrochalcones

Direct Parent

2'-Hydroxychalcones

Alternative Parents

Substituents

2'-hydroxychalcone
Cinnamylphenol
Methoxyphenol
Dimethoxybenzene
M-dimethoxybenzene
Methoxybenzene
Anisole
Benzoyl
Aryl ketone
Phenoxy compound
Styrene
Phenol ether
1-hydroxy-2-unsubstituted benzenoid
Alkyl aryl ether
1-hydroxy-4-unsubstituted benzenoid
Phenol
Monocyclic benzene moiety
Benzenoid
Vinylogous acid
Alpha,beta-unsaturated ketone
Enone
Acryloyl-group
Ketone
Ether
Organic oxide
Organic oxygen compound
Hydrocarbon derivative
Organooxygen compound
Aromatic homomonocyclic compound

Molecular Framework

Aromatic homomonocyclic compounds

External Descriptors

Chalcones and dihydrochalcones (LMPK12120285 )

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	3.54	ALOGPS
logP	3.61	ChemAxon
logS	-4.3	ALOGPS
pKa (Strongest Acidic)	8.19	ChemAxon
pKa (Strongest Basic)	-4.3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	6	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	74.22 Å²	ChemAxon
Rotatable Bond Count	7	ChemAxon
Refractivity	94.71 m³·mol⁻¹	ChemAxon
Polarizability	36.24 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

FDB001597

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

14034812

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Not Available

Showing NP-Card for Cerasidin (NP0045661)

MOL for NP0045661 (Cerasidin)

3D MOL for NP0045661 (Cerasidin)

3D SDF for NP0045661 (Cerasidin)

3D-SDF for NP0045661 (Cerasidin)

PDB for NP0045661 (Cerasidin)

3D PDB for NP0045661 (Cerasidin)

SMILES for NP0045661 (Cerasidin)

INCHI for NP0045661 (Cerasidin)

Structure for NP0045661 (Cerasidin)

3D Structure for NP0045661 (Cerasidin)