NP-MRD: Showing NP-Card for Tomatidenol (NP0044773)

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Record Information

Version

2.0

Created at

2022-02-24 21:15:38 UTC

Updated at

2026-02-13 16:01:29 UTC

NP-MRD ID

NP0044773

Natural Product DOI

https://doi.org/10.57994/6686

Secondary Accession Numbers

None

Natural Product Identification

Common Name

Tomatidenol

Description

Tomatidenol, also known as solasodine, belongs to the class of organic compounds known as spirosolanes and derivatives. These are steroidal alkaloids with a structure containing a spirosolane skeleton. Siporosolane is a polycyclic compound that is characterized by a 1-oxa-6-azaspiro[4.5]Decane moiety where the oxolane ring is fused to a docosahydronaphth[2,1:4',5']Indene ring system. Spirosolane arises from the conversion of a cholestane side-chain into a bicyclic system containing a piperidine and a tetrahydrofuran ring. Tomatidenol is found in Fritillaria camtschatcensis, Solanum dulcamara , Solanum havanense, Solanum lycopersicum and Solanum mammosum. Tomatidenol was first documented in 2002 (PMID: 11754948). Based on a literature review a significant number of articles have been published on Tomatidenol (PMID: 32441732) (PMID: 32270168) (PMID: 31334645) (PMID: 22180624) (PMID: 19514731).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652302242222152D          

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M  END

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 11 19  1  0  0  0  0
 17 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  1  0  0  0
 21 23  1  0  0  0  0
 23 24  1  0  0  0  0
 15 24  1  0  0  0  0
 12 25  1  6  0  0  0
 11 26  1  1  0  0  0
  9 27  1  6  0  0  0
  6 28  1  6  0  0  0
  5 29  1  6  0  0  0
  3 30  1  0  0  0  0
 30 31  1  0  0  0  0
 31 32  1  0  0  0  0
 32 33  1  6  0  0  0
 32 34  1  0  0  0  0
 34 35  1  0  0  0  0
  3 35  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0044773

> <DATABASE_NAME>
NP-MRD

> <SMILES>
[H][C@]12C[C@@]3([H])[C@]4([H])CC=C5C[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@]1(CC[C@H](C)CN1)O2

> <INCHI_IDENTIFIER>
InChI=1S/C27H43NO2/c1-16-7-12-27(28-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(29)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28-29H,6-15H2,1-4H3/t16-,17-,19-,20+,21-,22-,23-,24-,25-,26-,27-/m0/s1

> <INCHI_KEY>
KWVISVAMQJWJSZ-INULWVDGSA-N

> <FORMULA>
C27H43NO2

> <MOLECULAR_WEIGHT>
413.646

> <EXACT_MASS>
413.329379629

> <JCHEM_ACCEPTOR_COUNT>
3

> <JCHEM_ATOM_COUNT>
73

> <JCHEM_AVERAGE_POLARIZABILITY>
51.254982690903944

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
2

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(1S,2S,4S,5'S,6S,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethyl-5-oxaspiro[pentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-piperidin]-18-en-16-ol

> <ALOGPS_LOGP>
4.45

> <JCHEM_LOGP>
4.609877547333332

> <ALOGPS_LOGS>
-5.69

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
6

> <JCHEM_PHYSIOLOGICAL_CHARGE>
1

> <JCHEM_PKA_STRONGEST_ACIDIC>
18.204289505503816

> <JCHEM_PKA_STRONGEST_BASIC>
9.5416478856025

> <JCHEM_POLAR_SURFACE_AREA>
41.49

> <JCHEM_REFRACTIVITY>
121.94679999999998

> <JCHEM_ROTATABLE_BOND_COUNT>
0

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
8.38e-04 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(1S,2S,4S,5'S,6S,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethyl-5-oxaspiro[pentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-piperidin]-18-en-16-ol

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 24-FEB-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   24-FEB-22         0                                  
HETATM    1  C   UNK     0      10.606   3.125   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      10.374   1.603   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      11.469   0.520   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0      10.778  -0.856   0.000  0.00  0.00           O+0
HETATM    5  C   UNK     0       9.255  -0.624   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       9.006   0.896   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       7.483   1.128   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       8.315   2.424   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       6.792  -0.248   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       7.887  -1.331   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       5.255  -0.338   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       4.408   0.949   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       5.100   2.325   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       6.637   2.415   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       2.871   0.859   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       3.562   2.236   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       2.180  -0.517   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       3.026  -1.803   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       4.563  -1.714   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       0.642  -0.606   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      -0.204   0.681   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0      -1.741   0.591   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0       0.487   2.057   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0       2.025   2.146   0.000  0.00  0.00           C+0
HETATM   25  H   UNK     0       5.946   1.038   0.000  0.00  0.00           H+0
HETATM   26  H   UNK     0       3.717  -0.427   0.000  0.00  0.00           H+0
HETATM   27  H   UNK     0       6.249  -1.689   0.000  0.00  0.00           H+0
HETATM   28  H   UNK     0      10.382   0.205   0.000  0.00  0.00           H+0
HETATM   29  H   UNK     0       9.505  -2.143   0.000  0.00  0.00           H+0
HETATM   30  C   UNK     0      12.013   1.961   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0      13.532   2.211   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0      14.508   1.020   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0      16.028   1.269   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0      13.965  -0.421   0.000  0.00  0.00           C+0
HETATM   35  N   UNK     0      12.445  -0.671   0.000  0.00  0.00           N+0
CONECT    1    2                                                            
CONECT    2    1    3    6                                                  
CONECT    3    2    4   30   35                                             
CONECT    4    3    5                                                       
CONECT    5    4    6   10   29                                             
CONECT    6    5    2    7   28                                             
CONECT    7    6    8    9   14                                             
CONECT    8    7                                                            
CONECT    9    7   10   11   27                                             
CONECT   10    9    5                                                       
CONECT   11    9   12   19   26                                             
CONECT   12   11   13   15   25                                             
CONECT   13   12   14                                                       
CONECT   14   13    7                                                       
CONECT   15   12   16   17   24                                             
CONECT   16   15                                                            
CONECT   17   15   18   20                                                  
CONECT   18   17   19                                                       
CONECT   19   18   11                                                       
CONECT   20   17   21                                                       
CONECT   21   20   22   23                                                  
CONECT   22   21                                                            
CONECT   23   21   24                                                       
CONECT   24   23   15                                                       
CONECT   25   12                                                            
CONECT   26   11                                                            
CONECT   27    9                                                            
CONECT   28    6                                                            
CONECT   29    5                                                            
CONECT   30    3   31                                                       
CONECT   31   30   32                                                       
CONECT   32   31   33   34                                                  
CONECT   33   32                                                            
CONECT   34   32   35                                                       
CONECT   35   34    3                                                       
MASTER        0    0    0    0    0    0    0    0   35    0   80    0
END

View in JSmol

Synonyms

Value	Source
Solasodine citrate, (3alpha,22alpha,25R)-isomer	MeSH
Solasodine	MeSH
Solasodine, (3beta,22beta,25S)-isomer	MeSH

Chemical Formula

C₂₇H₄₃NO₂

Average Mass

413.6460 Da

Monoisotopic Mass

413.32938 Da

IUPAC Name

(1S,2S,4S,5'S,6S,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethyl-5-oxaspiro[pentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-piperidin]-18-en-16-ol

Traditional Name

(1S,2S,4S,5'S,6S,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethyl-5-oxaspiro[pentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-piperidin]-18-en-16-ol

CAS Registry Number

Not Available

SMILES

[H][C@]12C[C@@]3([H])[C@]4([H])CC=C5C[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@]1(CC[C@H](C)CN1)O2

InChI Identifier

InChI=1S/C27H43NO2/c1-16-7-12-27(28-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(29)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28-29H,6-15H2,1-4H3/t16-,17-,19-,20+,21-,22-,23-,24-,25-,26-,27-/m0/s1

InChI Key

KWVISVAMQJWJSZ-INULWVDGSA-N

Experimental Spectra

Spectrum Type	Description	Depositor Email	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 100 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 125 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 150 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 175 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 200 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 225 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 250 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Spectrum Type	Description	Depositor Email	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹H NMR Spectrum (1D, 300.0, Chloroform-d, simulated)	[email protected]	Not Available	Not Available	2026-02-13	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75.5, Chloroform-d, simulated)	[email protected]	Not Available	Not Available	2026-02-13	View Spectrum

Species

Species of Origin

Species Name	Source	Reference
Fritillaria camtschatcensis	Plant	KNApSAcK
Solanum aculeastrum		Not Available
Solanum dulcamara	Plant	KNApSAcK
Solanum havanense	Plant	KNApSAcK
Solanum lycopersicum	Plant	KNApSAcK
Solanum mammosum	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as spirosolanes and derivatives. These are steroidal alkaloids with a structure containing a spirosolane skeleton. Siporosolane is a polycyclic compound that is characterized by a 1-oxa-6-azaspiro[4.5]Decane moiety where the oxolane ring is fused to a docosahydronaphth[2,1:4',5']Indene ring system. Spirosolane arises from the conversion of a cholestane side-chain into a bicyclic system containing a piperidine and a tetrahydrofuran ring.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Steroids and steroid derivatives

Sub Class

Steroidal alkaloids

Direct Parent

Spirosolanes and derivatives

Alternative Parents

Substituents

Spirosolane skeleton
3-beta-hydroxysteroid
3-beta-hydroxy-delta-5-steroid
Hydroxysteroid
3-hydroxysteroid
3-hydroxy-delta-5-steroid
Delta-5-steroid
Azasteroid
Azaspirodecane
Alkaloid or derivatives
Piperidine
Tetrahydrofuran
Cyclic alcohol
Secondary alcohol
Hemiaminal
Oxacycle
Azacycle
Organoheterocyclic compound
Secondary amine
Secondary aliphatic amine
Organic nitrogen compound
Organic oxygen compound
Organopnictogen compound
Hydrocarbon derivative
Organooxygen compound
Organonitrogen compound
Amine
Alcohol
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	4.45	ALOGPS
logP	4.61	ChemAxon
logS	-5.7	ALOGPS
pKa (Strongest Acidic)	18.2	ChemAxon
pKa (Strongest Basic)	9.54	ChemAxon
Physiological Charge	1	ChemAxon
Hydrogen Acceptor Count	3	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	41.49 Å²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	121.95 m³·mol⁻¹	ChemAxon
Polarizability	51.25 Å³	ChemAxon
Number of Rings	6	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

C00029137

Chemspider ID

107562706

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

12442871

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Wang Y, Huang G, Shi Y, Tian WS, Zhuang C, Chen FE: Correction: Asymmetric synthesis of (-)-solanidine and (-)-tomatidenol. Org Biomol Chem. 2020 Jun 7;18(21):4114. doi: 10.1039/d0ob90067b. Epub 2020 May 22. [PubMed:32441732 ]
Wang Y, Huang G, Shi Y, Tian WS, Zhuang C, Chen FE: Asymmetric synthesis of (-)-solanidine and (-)-tomatidenol. Org Biomol Chem. 2020 Apr 29;18(16):3169-3176. doi: 10.1039/d0ob00457j. [PubMed:32270168 ]
Bednarz H, Roloff N, Niehaus K: Mass Spectrometry Imaging of the Spatial and Temporal Localization of Alkaloids in Nightshades. J Agric Food Chem. 2019 Dec 11;67(49):13470-13477. doi: 10.1021/acs.jafc.9b01155. Epub 2019 Jul 23. [PubMed:31334645 ]
Itkin M, Rogachev I, Alkan N, Rosenberg T, Malitsky S, Masini L, Meir S, Iijima Y, Aoki K, de Vos R, Prusky D, Burdman S, Beekwilder J, Aharoni A: GLYCOALKALOID METABOLISM1 is required for steroidal alkaloid glycosylation and prevention of phytotoxicity in tomato. Plant Cell. 2011 Dec;23(12):4507-25. doi: 10.1105/tpc.111.088732. Epub 2011 Dec 16. [PubMed:22180624 ]
Friedman M, Levin CE, Lee SU, Kim HJ, Lee IS, Byun JO, Kozukue N: Tomatine-containing green tomato extracts inhibit growth of human breast, colon, liver, and stomach cancer cells. J Agric Food Chem. 2009 Jul 8;57(13):5727-33. doi: 10.1021/jf900364j. [PubMed:19514731 ]
Wanyonyi AW, Chhabra SC, Mkoji G, Eilert U, Njue WM: Bioactive steroidal alkaloid glycosides from Solanum aculeastrum. Phytochemistry. 2002 Jan;59(1):79-84. doi: 10.1016/s0031-9422(01)00424-1. [PubMed:11754948 ]
Alphonse W Wanyonyi, Sumesh C Chhabra, Gerald Mkoji, Udo Eilert, Wilson M Njue (2002). Alphonse W Wanyonyi, Sumesh C Chhabra, Gerald Mkoji, Udo Eilert, Wilson M Njue. Bioactive steroidal alkaloid glycosides from Solanum aculeastrum. Phytochemistry 59(1), January 2002, Pages 79-84. 10.1016/S0031-9422(01)00424-1. Phytochemistry.
DOI: 10.1016/s0031-9422(01)00424-1
PMID: 11754948

Showing NP-Card for Tomatidenol (NP0044773)

MOL for NP0044773 (Tomatidenol)

3D MOL for NP0044773 (Tomatidenol)

3D SDF for NP0044773 (Tomatidenol)

3D-SDF for NP0044773 (Tomatidenol)

PDB for NP0044773 (Tomatidenol)

3D PDB for NP0044773 (Tomatidenol)

SMILES for NP0044773 (Tomatidenol)

INCHI for NP0044773 (Tomatidenol)

Structure for NP0044773 (Tomatidenol)

3D Structure for NP0044773 (Tomatidenol)