NP-MRD: Showing NP-Card for 9alpha-hydroxyparthenolide (NP0044130)

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Record Information

Version

1.0

Created at

2021-11-12 23:51:41 UTC

Updated at

2021-11-26 17:45:45 UTC

NP-MRD ID

NP0044130

Secondary Accession Numbers

None

Natural Product Identification

Common Name

9alpha-hydroxyparthenolide

Description

(1S,2R,4R,7E,9R,11S)-9-hydroxy-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.0²,⁴]Tetradec-7-en-13-one belongs to the class of organic compounds known as germacranolides and derivatives. These are sesquiterpene lactones with a structure based on the germacranolide skeleton, characterized by a gamma lactone fused to a 1,7-dimethylcyclodec-1-ene moiety. 9alpha-hydroxyparthenolide is found in Anthemis punctata subsp. cupaniana, Anvillea garcinii, Avila garcini, Inula verbascifolia ssp.methanea and Zoegea baldschuanica. It was first documented in 2019 (PMID: 30634079). Based on a literature review a significant number of articles have been published on (1S,2R,4R,7E,9R,11S)-9-hydroxy-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.0²,⁴]Tetradec-7-en-13-one (PMID: 34756847) (PMID: 34758548) (PMID: 34758547) (PMID: 34758546).

Structure

MOL 3D MOL SDF PDB SMILES InChI

     RDKit          3D

 39 41  0  0  0  0  0  0  0  0999 V2000
   -2.4434    2.8559    0.6091 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1764    2.6883    0.3147 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0139    3.4449    0.7902 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0557    4.4210    1.5884 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.1296    2.8721    0.1875 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7711    1.5120   -0.0201 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.6243    1.6813   -0.5785 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.3813    0.4425   -0.7880 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3847   -0.5690    0.3059 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.6971   -0.5442    0.8486 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1238   -1.9479   -0.1930 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2738   -2.6610   -0.8769 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0360   -2.5615   -0.0691 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2614   -2.0171    0.5683 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2706   -1.5351   -0.4856 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5591   -0.1145   -0.1844 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.0124    0.2268    1.1946 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9289    0.8142   -1.1314 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.5932    0.7423   -0.9408 C   0  0  2  0  0  0  0  0  0  0  0  0
   -3.1727    2.2004    0.1628 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8226    3.6164    1.2791 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.6585    1.0858    0.9925 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4917    2.1707   -1.5795 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9552   -0.0688   -1.6988 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4158    0.7325   -1.1129 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7394   -0.3760    1.1545 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3450   -0.2481    0.1683 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8067   -3.3196   -0.1762 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8943   -3.2412   -1.7437 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9714   -1.9057   -1.2875 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1395   -3.5880   -0.4725 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.0568   -1.2515    1.3227 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.7836   -2.8756    1.0928 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.7376   -1.6096   -1.4788 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.1374   -2.1911   -0.5566 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9405   -0.6781    1.8402 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.1258    0.4193    1.1246 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.5897    1.1288    1.6302 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.0574    0.2483   -1.8004 H   0  0  0  0  0  0  0  0  0  0  0  0
 16 17  1  1
 16 19  1  0
 19  6  1  0
  6  7  1  0
  7  2  1  0
  2  1  2  3
  2  3  1  0
  3  4  2  0
  3  5  1  0
  7  8  1  0
  8  9  1  0
  9 10  1  0
  9 11  1  0
 11 12  1  0
 11 13  2  0
 13 14  1  0
 14 15  1  0
 19 18  1  0
 15 16  1  0
 18 16  1  0
  5  6  1  0
 17 36  1  0
 17 37  1  0
 17 38  1  0
 19 39  1  6
  6 22  1  1
  7 23  1  6
  1 20  1  0
  1 21  1  0
  8 24  1  0
  8 25  1  0
  9 26  1  1
 10 27  1  0
 12 28  1  0
 12 29  1  0
 12 30  1  0
 13 31  1  0
 14 32  1  0
 14 33  1  0
 15 34  1  0
 15 35  1  0
M  END


  Mrv1652311132100512D          

 22 24  0  0  1  0            999 V2000
    2.8192    1.7019    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0177    1.8976    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.2912    1.5068    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.4737    1.6176    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.1225    2.1879    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.8491    1.7970    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5923    2.1551    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7019    0.9853    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2721    0.3891    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.1156    0.8744    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2697    2.9996    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0883    3.7429    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.3025    4.4694    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.9059    3.6320    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0530    2.8202    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6324    4.0228    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2286    3.4526    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3758    2.6408    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2334    1.3703    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.8317    2.3609    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9929    1.0730    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0128    0.7302    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
  2  1  1  6  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  2  0  0  0  0
  6  8  1  0  0  0  0
  8  9  2  0  0  0  0
  8 10  1  0  0  0  0
  4 10  1  0  0  0  0
  5 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  1  0  0  0
 12 14  1  0  0  0  0
 14 15  1  0  0  0  0
 14 16  2  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
  2 18  1  0  0  0  0
  5 19  1  1  0  0  0
  4 20  1  6  0  0  0
  3 21  1  0  0  0  0
  2 21  1  0  0  0  0
  3 22  1  1  0  0  0
M  END
> <DATABASE_ID>
NP0044130

> <DATABASE_NAME>
NP-MRD

> <SMILES>
[H][C@]12O[C@]1(C)CC\C=C(C)\[C@H](O)C[C@@]1([H])C(=C)C(=O)O[C@]21[H]

> <INCHI_IDENTIFIER>
InChI=1S/C15H20O4/c1-8-5-4-6-15(3)13(19-15)12-10(7-11(8)16)9(2)14(17)18-12/h5,10-13,16H,2,4,6-7H2,1,3H3/b8-5+/t10-,11+,12-,13+,15+/m0/s1

> <INCHI_KEY>
RZUCCKARTVHQBW-AMTRQYNDSA-N

> <FORMULA>
C15H20O4

> <MOLECULAR_WEIGHT>
264.321

> <EXACT_MASS>
264.136159124

> <JCHEM_ACCEPTOR_COUNT>
3

> <JCHEM_ATOM_COUNT>
39

> <JCHEM_AVERAGE_POLARIZABILITY>
27.37594915591247

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
(1S,2R,4R,7E,9R,11S)-9-hydroxy-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.0^{2,4}]tetradec-7-en-13-one

> <ALOGPS_LOGP>
1.62

> <JCHEM_LOGP>
1.8404815313333334

> <ALOGPS_LOGS>
-2.07

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
3

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_ACIDIC>
14.602904780791715

> <JCHEM_PKA_STRONGEST_BASIC>
-2.972489448881703

> <JCHEM_POLAR_SURFACE_AREA>
59.06

> <JCHEM_REFRACTIVITY>
70.0684

> <JCHEM_ROTATABLE_BOND_COUNT>
0

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
2.23e+00 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(1S,2R,4R,7E,9R,11S)-9-hydroxy-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.0^{2,4}]tetradec-7-en-13-one

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 13-NOV-21   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   13-NOV-21         0                                  
HETATM    1  C   UNK     0       5.262   3.177   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       3.766   3.542   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       2.410   2.813   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       0.884   3.020   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -0.229   4.084   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -1.585   3.354   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      -2.972   4.023   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      -1.310   1.839   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0      -2.375   0.726   0.000  0.00  0.00           O+0
HETATM   10  O   UNK     0       0.216   1.632   0.000  0.00  0.00           O+0
HETATM   11  C   UNK     0      -0.503   5.599   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       0.165   6.987   0.000  0.00  0.00           C+0
HETATM   13  O   UNK     0      -0.565   8.343   0.000  0.00  0.00           O+0
HETATM   14  C   UNK     0       1.691   6.780   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       1.966   5.264   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       3.047   7.509   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       4.160   6.445   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       4.435   4.930   0.000  0.00  0.00           C+0
HETATM   19  H   UNK     0      -0.436   2.558   0.000  0.00  0.00           H+0
HETATM   20  H   UNK     0       1.553   4.407   0.000  0.00  0.00           H+0
HETATM   21  O   UNK     0       3.720   2.003   0.000  0.00  0.00           O+0
HETATM   22  H   UNK     0       1.890   1.363   0.000  0.00  0.00           H+0
CONECT    1    2                                                            
CONECT    2    1    3   18   21                                             
CONECT    3    2    4   21   22                                             
CONECT    4    3    5   10   20                                             
CONECT    5    4    6   11   19                                             
CONECT    6    5    7    8                                                  
CONECT    7    6                                                            
CONECT    8    6    9   10                                                  
CONECT    9    8                                                            
CONECT   10    8    4                                                       
CONECT   11    5   12                                                       
CONECT   12   11   13   14                                                  
CONECT   13   12                                                            
CONECT   14   12   15   16                                                  
CONECT   15   14                                                            
CONECT   16   14   17                                                       
CONECT   17   16   18                                                       
CONECT   18   17    2                                                       
CONECT   19    5                                                            
CONECT   20    4                                                            
CONECT   21    3    2                                                       
CONECT   22    3                                                            
MASTER        0    0    0    0    0    0    0    0   22    0   48    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₁₅H₂₀O₄

Average Mass

264.3210 Da

Monoisotopic Mass

264.13616 Da

IUPAC Name

(1S,2R,4R,7E,9R,11S)-9-hydroxy-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.0^{2,4}]tetradec-7-en-13-one

Traditional Name

(1S,2R,4R,7E,9R,11S)-9-hydroxy-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.0^{2,4}]tetradec-7-en-13-one

CAS Registry Number

Not Available

SMILES

[H][C@]12O[C@]1(C)CC\C=C(C)\[C@H](O)C[C@@]1([H])C(=C)C(=O)O[C@]21[H]

InChI Identifier

InChI=1S/C15H20O4/c1-8-5-4-6-15(3)13(19-15)12-10(7-11(8)16)9(2)14(17)18-12/h5,10-13,16H,2,4,6-7H2,1,3H3/b8-5+/t10-,11+,12-,13+,15+/m0/s1

InChI Key

RZUCCKARTVHQBW-AMTRQYNDSA-N

Experimental Spectra

Spectrum Type	Description	Depositor Email	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 150 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 250 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 175 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 100 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 225 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 200 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 125 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, Chloroform-d, simulated)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Predicted Spectra

Not Available

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Anthemis punctata subsp. cupaniana	Plant	KNApSAcK
Anvillea garcinii	Plant	KNApSAcK
Avila garcini	-	KNApSAcK
Inula verbascifolia ssp.methanea	Plant	KNApSAcK
Zoegea baldschuanica	Plant	KNApSAcK

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as germacranolides and derivatives. These are sesquiterpene lactones with a structure based on the germacranolide skeleton, characterized by a gamma lactone fused to a 1,7-dimethylcyclodec-1-ene moiety.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Terpene lactones

Direct Parent

Germacranolides and derivatives

Alternative Parents

Substituents

Germacranolide
Germacrane sesquiterpenoid
Sesquiterpenoid
Gamma butyrolactone
Alpha,beta-unsaturated carboxylic ester
Enoate ester
Oxolane
Carboxylic acid ester
Lactone
Secondary alcohol
Carboxylic acid derivative
Dialkyl ether
Oxirane
Ether
Oxacycle
Organoheterocyclic compound
Monocarboxylic acid or derivatives
Alcohol
Organic oxide
Hydrocarbon derivative
Organic oxygen compound
Carbonyl group
Organooxygen compound
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	1.62	ALOGPS
logP	1.84	ChemAxon
logS	-2.1	ALOGPS
pKa (Strongest Acidic)	14.6	ChemAxon
pKa (Strongest Basic)	-3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	3	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	59.06 Å²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	70.07 m³·mol⁻¹	ChemAxon
Polarizability	27.38 Å³	ChemAxon
Number of Rings	3	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

10236930

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

14466183

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Nawrot J, Budzianowski J, Nowak G: Phytochemical profiles of the leaves of Stizolophus balsamita and Psephellus sibiricus and their chemotaxonomic implications. Phytochemistry. 2019 Mar;159:172-178. doi: 10.1016/j.phytochem.2018.12.022. Epub 2019 Jan 9. [PubMed:30634079 ]
McDonagh MS, Wagner J, Ahmed AY, Morasco B, Kansagara D, Chou R: Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain - Quarterly Progress Report/Addendum: September 2021. 2020 Dec. [PubMed:34756847 ]
Zhang WB, Yang QB, Wu SF, Lu SH, Cheng M, Sheng Y, Zhang QC, Yang LF, Yu L, Yan SX: [Application of diffusion-weighted magnetic resonance imaging in evaluating the efficacy of radiotherapy and chemotherapy for esophageal cancer]. Zhonghua Yi Xue Za Zhi. 2021 Nov 9;101(41):3427-3430. doi: 10.3760/cma.j.cn112137-20210709-01544. [PubMed:34758548 ]
Sun Y, Wang DM, Yu H, Liu C, Ji TY, Wang S, Wu Y, Liu XY, Jiang YW, Cai LX, Liu QZ: [The screening of potential biological markers of seizure onset zone in focal cortical dysplasia based on bioinformatics analysis]. Zhonghua Yi Xue Za Zhi. 2021 Nov 9;101(41):3422-3426. doi: 10.3760/cma.j.cn112137-20210331-00779. [PubMed:34758547 ]
Dong HH, Cai YS, Liang XN, Miao JB, Chen QS, Gao YD, Li H: [Analysis of incidence and risk factors for postoperative venous thromboembolism in patients with stage a non-small-cell lung cancer]. Zhonghua Yi Xue Za Zhi. 2021 Nov 9;101(41):3417-3421. doi: 10.3760/cma.j.cn112137-20210418-00929. [PubMed:34758546 ]

Showing NP-Card for 9alpha-hydroxyparthenolide (NP0044130)

MOL for NP0044130 (9alpha-hydroxyparthenolide)

3D MOL for NP0044130 (9alpha-hydroxyparthenolide)

3D SDF for NP0044130 (9alpha-hydroxyparthenolide)

3D-SDF for NP0044130 (9alpha-hydroxyparthenolide)

PDB for NP0044130 (9alpha-hydroxyparthenolide)

3D PDB for NP0044130 (9alpha-hydroxyparthenolide)

SMILES for NP0044130 (9alpha-hydroxyparthenolide)

INCHI for NP0044130 (9alpha-hydroxyparthenolide)

Structure for NP0044130 (9alpha-hydroxyparthenolide)

3D Structure for NP0044130 (9alpha-hydroxyparthenolide)