Record Information |
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Version | 1.0 |
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Created at | 2021-01-06 07:24:08 UTC |
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Updated at | 2021-07-15 17:38:20 UTC |
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NP-MRD ID | NP0022175 |
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Secondary Accession Numbers | None |
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Natural Product Identification |
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Common Name | Carbazomycin B |
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Provided By | NPAtlas |
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Description | Carbazomycin B is found in Streptomyces abikoensis, Streptomyces ehimensis, Streptomyces luteoverticillatus and Streptomyces sp.. It was first documented in 1980 (PMID: 7440417). Based on a literature review very few articles have been published on 3-methoxy-1,2-dimethyl-9H-carbazol-4-ol (PMID: 31168648) (PMID: 25296703) (PMID: 33841348). |
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Structure | [H]OC1=C2C3=C([H])C([H])=C([H])C([H])=C3N([H])C2=C(C(=C1OC([H])([H])[H])C([H])([H])[H])C([H])([H])[H] InChI=1S/C15H15NO2/c1-8-9(2)15(18-3)14(17)12-10-6-4-5-7-11(10)16-13(8)12/h4-7,16-17H,1-3H3 |
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Synonyms | Value | Source |
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4-Hydroxy-3-methoxy-1,2-dimethylcarbazole | MeSH |
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Chemical Formula | C15H15NO2 |
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Average Mass | 241.2900 Da |
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Monoisotopic Mass | 241.11028 Da |
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IUPAC Name | 3-methoxy-1,2-dimethyl-9H-carbazol-4-ol |
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Traditional Name | 3-methoxy-1,2-dimethyl-9H-carbazol-4-ol |
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CAS Registry Number | Not Available |
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SMILES | COC1=C(O)C2=C(NC3=CC=CC=C23)C(C)=C1C |
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InChI Identifier | InChI=1S/C15H15NO2/c1-8-9(2)15(18-3)14(17)12-10-6-4-5-7-11(10)16-13(8)12/h4-7,16-17H,1-3H3 |
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InChI Key | OBMFXFPFPDTBHG-UHFFFAOYSA-N |
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Experimental Spectra |
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| Not Available | Predicted Spectra |
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| Spectrum Type | Description | Depositor ID | Depositor Organization | Depositor | Deposition Date | View |
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1D NMR | 13C NMR Spectrum (1D, 25 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 100 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 252 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 1000 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 50 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 200 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 75 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 300 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 101 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 400 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 126 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 500 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 151 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 600 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 176 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 700 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 201 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 800 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 226 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 1H NMR Spectrum (1D, 900 MHz, D2O, predicted) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum |
| Chemical Shift Submissions |
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| Not Available | Species |
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Species of Origin | |
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Species Where Detected | |
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Chemical Taxonomy |
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Description | This compound belongs to the class of organic compounds known as carbazoles. These are compounds containing a three ring system containing a pyrrole ring fused on either side to a benzene ring. |
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Kingdom | Organic compounds |
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Super Class | Organoheterocyclic compounds |
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Class | Indoles and derivatives |
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Sub Class | Carbazoles |
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Direct Parent | Carbazoles |
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Alternative Parents | |
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Substituents | - Carbazole
- Hydroxyindole
- Indole
- Anisole
- Alkyl aryl ether
- Benzenoid
- Heteroaromatic compound
- Pyrrole
- Ether
- Azacycle
- Organonitrogen compound
- Hydrocarbon derivative
- Organic nitrogen compound
- Organopnictogen compound
- Organooxygen compound
- Organic oxygen compound
- Aromatic heteropolycyclic compound
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Molecular Framework | Aromatic heteropolycyclic compounds |
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External Descriptors | Not Available |
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Physical Properties |
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State | Not Available |
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Experimental Properties | Property | Value | Reference |
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Melting Point | Not Available | Not Available | Boiling Point | Not Available | Not Available | Water Solubility | Not Available | Not Available | LogP | Not Available | Not Available |
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Predicted Properties | |
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General References | - Sakano K, Nakamura S: New antibiotics, carbazomycins A and B. II. Structural elucidation. J Antibiot (Tokyo). 1980 Sep;33(9):961-6. doi: 10.7164/antibiotics.33.961. [PubMed:7440417 ]
- Feng Z, Chen G, Zhang J, Zhu H, Yu X, Yin Y, Zhang X: Characterization and Complete Genome Analysis of the Carbazomycin B-Producing Strain Streptomyces luteoverticillatus SZJ61. Curr Microbiol. 2019 Sep;76(9):982-987. doi: 10.1007/s00284-019-01711-x. Epub 2019 Jun 5. [PubMed:31168648 ]
- Markad SB, Argade NP: Diversity oriented convergent access for collective total synthesis of bioactive multifunctional carbazole alkaloids: synthesis of carbazomycin A, carbazomycin B, hyellazole, chlorohyellazole, and clausenaline D. Org Lett. 2014 Oct 17;16(20):5470-3. doi: 10.1021/ol502721r. Epub 2014 Oct 9. [PubMed:25296703 ]
- Shi T, Guo X, Zhu J, Hu L, He Z, Jiang D: Inhibitory Effects of Carbazomycin B Produced by Streptomyces roseoverticillatus 63 Against Xanthomonas oryzae pv. oryzae. Front Microbiol. 2021 Mar 24;12:616937. doi: 10.3389/fmicb.2021.616937. eCollection 2021. [PubMed:33841348 ]
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