NP-MRD: Showing NP-Card for Mm 22383 (NP0021544)

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Record Information

Version

2.0

Created at

2021-01-06 06:50:13 UTC

Updated at

2021-07-15 17:36:38 UTC

NP-MRD ID

NP0021544

Secondary Accession Numbers

None

Natural Product Identification

Common Name

Mm 22383

Provided By

NPAtlas

Description

Carbapenem MM22383 is also known as MM22383. Mm 22383 is found in Streptomyces olivaceus. Mm 22383 was first documented in 1979 (PMID: 511786). Based on a literature review very few articles have been published on carbapenem MM22383 (PMID: 3338858).

Structure

MOL 3D MOL SDF 3D SDF PDB SMILES InChI


  Mrv1652306242105163D          

 37 38  0  0  0  0            999 V2000
    6.8091   -0.3993    0.3046 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4862    0.0360   -0.1584 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8775   -0.6158   -1.0416 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8957    1.1960    0.3945 N   0  0  0  0  0  0  0  0  0  0  0  0
    3.6177    1.6319   -0.0407 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6394    1.7045    0.8916 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0543    2.2278    0.4357 S   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1898    1.0129    0.2175 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2559   -0.2867    0.3306 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8241   -1.1709    0.7162 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9602   -0.8337    0.9936 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5571   -2.5492    0.7825 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5757   -0.7600    0.0169 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7458   -1.4809   -0.1313 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1183   -2.6647   -0.3008 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4687   -0.1749    0.0020 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.7369   -0.0738   -0.7904 C   0  0  2  0  0  0  0  0  0  0  0  0
   -5.6975   -1.1579   -0.3357 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5125   -0.0816   -2.1451 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2280    0.3246   -0.7015 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.5804    1.5548   -0.2097 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.7877   -1.0500    1.1961 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.3981    0.5074    0.5782 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.3703   -0.8609   -0.5486 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3864    1.7548    1.1326 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3797    1.9054   -1.0537 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9345    1.4345    1.9251 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2251   -3.1700    0.3424 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5067    0.1214    1.0463 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2131    0.8921   -0.5214 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.6948   -0.8736   -0.7644 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3686   -2.1489   -0.6661 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7905   -1.0587    0.7669 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7481    0.7771   -2.5860 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1968    0.1179   -1.7849 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4663    2.2772   -1.0153 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1089    1.9353    0.6820 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  2  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  2  0  0  0  0
  9 10  1  0  0  0  0
 10 11  2  0  0  0  0
 10 12  1  0  0  0  0
  9 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  2  0  0  0  0
 14 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 17 19  1  0  0  0  0
 16 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21  8  1  0  0  0  0
 20 13  1  0  0  0  0
  1 22  1  0  0  0  0
  1 23  1  0  0  0  0
  1 24  1  0  0  0  0
  4 25  1  0  0  0  0
  5 26  1  0  0  0  0
  6 27  1  0  0  0  0
 12 28  1  0  0  0  0
 16 29  1  1  0  0  0
 17 30  1  1  0  0  0
 18 31  1  0  0  0  0
 18 32  1  0  0  0  0
 18 33  1  0  0  0  0
 19 34  1  0  0  0  0
 20 35  1  6  0  0  0
 21 36  1  0  0  0  0
 21 37  1  0  0  0  0
M  END

     RDKit          3D

 37 38  0  0  0  0  0  0  0  0999 V2000
    6.8091   -0.3993    0.3046 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4862    0.0360   -0.1584 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8775   -0.6158   -1.0416 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8957    1.1960    0.3945 N   0  0  0  0  0  0  0  0  0  0  0  0
    3.6177    1.6319   -0.0407 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6394    1.7045    0.8916 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0543    2.2278    0.4357 S   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1898    1.0129    0.2175 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2559   -0.2867    0.3306 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8241   -1.1709    0.7162 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9602   -0.8337    0.9936 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5571   -2.5492    0.7825 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5757   -0.7600    0.0169 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7458   -1.4809   -0.1313 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1183   -2.6647   -0.3008 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4687   -0.1749    0.0020 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.7369   -0.0738   -0.7904 C   0  0  2  0  0  0  0  0  0  0  0  0
   -5.6975   -1.1579   -0.3357 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5125   -0.0816   -2.1451 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2280    0.3246   -0.7015 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.5804    1.5548   -0.2097 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.7877   -1.0500    1.1961 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.3981    0.5074    0.5782 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.3703   -0.8609   -0.5486 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3864    1.7548    1.1326 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3797    1.9054   -1.0537 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9345    1.4345    1.9251 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2251   -3.1700    0.3424 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5067    0.1214    1.0463 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2131    0.8921   -0.5214 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.6948   -0.8736   -0.7644 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3686   -2.1489   -0.6661 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7905   -1.0587    0.7669 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7481    0.7771   -2.5860 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1968    0.1179   -1.7849 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4663    2.2772   -1.0153 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1089    1.9353    0.6820 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  2  0
  2  4  1  0
  4  5  1  0
  5  6  2  0
  6  7  1  0
  7  8  1  0
  8  9  2  0
  9 10  1  0
 10 11  2  0
 10 12  1  0
  9 13  1  0
 13 14  1  0
 14 15  2  0
 14 16  1  0
 16 17  1  0
 17 18  1  0
 17 19  1  0
 16 20  1  0
 20 21  1  0
 21  8  1  0
 20 13  1  0
  1 22  1  0
  1 23  1  0
  1 24  1  0
  4 25  1  0
  5 26  1  0
  6 27  1  0
 12 28  1  0
 16 29  1  1
 17 30  1  1
 18 31  1  0
 18 32  1  0
 18 33  1  0
 19 34  1  0
 20 35  1  6
 21 36  1  0
 21 37  1  0
M  END


  Mrv1652306242105163D          

 37 38  0  0  0  0            999 V2000
    6.8091   -0.3993    0.3046 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4862    0.0360   -0.1584 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8775   -0.6158   -1.0416 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8957    1.1960    0.3945 N   0  0  0  0  0  0  0  0  0  0  0  0
    3.6177    1.6319   -0.0407 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6394    1.7045    0.8916 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0543    2.2278    0.4357 S   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1898    1.0129    0.2175 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2559   -0.2867    0.3306 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8241   -1.1709    0.7162 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9602   -0.8337    0.9936 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5571   -2.5492    0.7825 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5757   -0.7600    0.0169 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7458   -1.4809   -0.1313 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1183   -2.6647   -0.3008 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4687   -0.1749    0.0020 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.7369   -0.0738   -0.7904 C   0  0  2  0  0  0  0  0  0  0  0  0
   -5.6975   -1.1579   -0.3357 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5125   -0.0816   -2.1451 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2280    0.3246   -0.7015 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.5804    1.5548   -0.2097 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.7877   -1.0500    1.1961 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.3981    0.5074    0.5782 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.3703   -0.8609   -0.5486 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3864    1.7548    1.1326 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3797    1.9054   -1.0537 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9345    1.4345    1.9251 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2251   -3.1700    0.3424 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5067    0.1214    1.0463 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2131    0.8921   -0.5214 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.6948   -0.8736   -0.7644 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3686   -2.1489   -0.6661 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7905   -1.0587    0.7669 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7481    0.7771   -2.5860 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1968    0.1179   -1.7849 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4663    2.2772   -1.0153 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1089    1.9353    0.6820 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  2  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  2  0  0  0  0
  9 10  1  0  0  0  0
 10 11  2  0  0  0  0
 10 12  1  0  0  0  0
  9 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  2  0  0  0  0
 14 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 17 19  1  0  0  0  0
 16 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21  8  1  0  0  0  0
 20 13  1  0  0  0  0
  1 22  1  0  0  0  0
  1 23  1  0  0  0  0
  1 24  1  0  0  0  0
  4 25  1  0  0  0  0
  5 26  1  0  0  0  0
  6 27  1  0  0  0  0
 12 28  1  0  0  0  0
 16 29  1  1  0  0  0
 17 30  1  1  0  0  0
 18 31  1  0  0  0  0
 18 32  1  0  0  0  0
 18 33  1  0  0  0  0
 19 34  1  0  0  0  0
 20 35  1  6  0  0  0
 21 36  1  0  0  0  0
 21 37  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0021544

> <DATABASE_NAME>
NP-MRD

> <SMILES>
[H]OC(=O)C1=C(S\C([H])=C(/[H])N([H])C(=O)C([H])([H])[H])C([H])([H])[C@@]2([H])N1C(=O)[C@]2([H])[C@@]([H])(O[H])C([H])([H])[H]

> <INCHI_IDENTIFIER>
InChI=1S/C13H16N2O5S/c1-6(16)10-8-5-9(21-4-3-14-7(2)17)11(13(19)20)15(8)12(10)18/h3-4,6,8,10,16H,5H2,1-2H3,(H,14,17)(H,19,20)/b4-3+/t6-,8+,10+/m0/s1

> <INCHI_KEY>
PRPNUZWHFGSGRV-RZFSBTTISA-N

> <FORMULA>
C13H16N2O5S

> <MOLECULAR_WEIGHT>
312.34

> <EXACT_MASS>
312.077992797

> <JCHEM_ACCEPTOR_COUNT>
5

> <JCHEM_ATOM_COUNT>
37

> <JCHEM_AVERAGE_POLARIZABILITY>
31.666367053517764

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
3

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(5R,6S)-3-{[(E)-2-acetamidoethenyl]sulfanyl}-6-[(1S)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

> <ALOGPS_LOGP>
0.19

> <JCHEM_LOGP>
-2.2815035809999995

> <ALOGPS_LOGS>
-2.05

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA>
13.985376725464246

> <JCHEM_PKA_STRONGEST_ACIDIC>
3.855342544127985

> <JCHEM_PKA_STRONGEST_BASIC>
-2.7977614319212165

> <JCHEM_POLAR_SURFACE_AREA>
106.94000000000001

> <JCHEM_REFRACTIVITY>
77.5701

> <JCHEM_ROTATABLE_BOND_COUNT>
5

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
2.81e+00 g/l

> <JCHEM_TRADITIONAL_IUPAC>
carbapenem MM22383

> <JCHEM_VEBER_RULE>
0

$$$$

     RDKit          3D

 37 38  0  0  0  0  0  0  0  0999 V2000
    6.8091   -0.3993    0.3046 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4862    0.0360   -0.1584 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8775   -0.6158   -1.0416 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8957    1.1960    0.3945 N   0  0  0  0  0  0  0  0  0  0  0  0
    3.6177    1.6319   -0.0407 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6394    1.7045    0.8916 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0543    2.2278    0.4357 S   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1898    1.0129    0.2175 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2559   -0.2867    0.3306 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8241   -1.1709    0.7162 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9602   -0.8337    0.9936 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5571   -2.5492    0.7825 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5757   -0.7600    0.0169 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7458   -1.4809   -0.1313 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1183   -2.6647   -0.3008 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4687   -0.1749    0.0020 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.7369   -0.0738   -0.7904 C   0  0  2  0  0  0  0  0  0  0  0  0
   -5.6975   -1.1579   -0.3357 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5125   -0.0816   -2.1451 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2280    0.3246   -0.7015 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.5804    1.5548   -0.2097 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.7877   -1.0500    1.1961 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.3981    0.5074    0.5782 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.3703   -0.8609   -0.5486 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3864    1.7548    1.1326 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3797    1.9054   -1.0537 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9345    1.4345    1.9251 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2251   -3.1700    0.3424 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5067    0.1214    1.0463 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2131    0.8921   -0.5214 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.6948   -0.8736   -0.7644 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3686   -2.1489   -0.6661 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7905   -1.0587    0.7669 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7481    0.7771   -2.5860 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1968    0.1179   -1.7849 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4663    2.2772   -1.0153 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1089    1.9353    0.6820 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  2  0
  2  4  1  0
  4  5  1  0
  5  6  2  0
  6  7  1  0
  7  8  1  0
  8  9  2  0
  9 10  1  0
 10 11  2  0
 10 12  1  0
  9 13  1  0
 13 14  1  0
 14 15  2  0
 14 16  1  0
 16 17  1  0
 17 18  1  0
 17 19  1  0
 16 20  1  0
 20 21  1  0
 21  8  1  0
 20 13  1  0
  1 22  1  0
  1 23  1  0
  1 24  1  0
  4 25  1  0
  5 26  1  0
  6 27  1  0
 12 28  1  0
 16 29  1  1
 17 30  1  1
 18 31  1  0
 18 32  1  0
 18 33  1  0
 19 34  1  0
 20 35  1  6
 21 36  1  0
 21 37  1  0
M  END

HEADER    PROTEIN                                 24-JUN-21   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   24-JUN-21         0                                  
HETATM    1  C   UNK     0       6.809  -0.399   0.305  0.00  0.00           C+0
HETATM    2  C   UNK     0       5.486   0.036  -0.158  0.00  0.00           C+0
HETATM    3  O   UNK     0       4.878  -0.616  -1.042  0.00  0.00           O+0
HETATM    4  N   UNK     0       4.896   1.196   0.395  0.00  0.00           N+0
HETATM    5  C   UNK     0       3.618   1.632  -0.041  0.00  0.00           C+0
HETATM    6  C   UNK     0       2.639   1.704   0.892  0.00  0.00           C+0
HETATM    7  S   UNK     0       1.054   2.228   0.436  0.00  0.00           S+0
HETATM    8  C   UNK     0      -0.190   1.013   0.218  0.00  0.00           C+0
HETATM    9  C   UNK     0      -0.256  -0.287   0.331  0.00  0.00           C+0
HETATM   10  C   UNK     0       0.824  -1.171   0.716  0.00  0.00           C+0
HETATM   11  O   UNK     0       1.960  -0.834   0.994  0.00  0.00           O+0
HETATM   12  O   UNK     0       0.557  -2.549   0.783  0.00  0.00           O+0
HETATM   13  N   UNK     0      -1.576  -0.760   0.017  0.00  0.00           N+0
HETATM   14  C   UNK     0      -2.746  -1.481  -0.131  0.00  0.00           C+0
HETATM   15  O   UNK     0      -3.118  -2.665  -0.301  0.00  0.00           O+0
HETATM   16  C   UNK     0      -3.469  -0.175   0.002  0.00  0.00           C+0
HETATM   17  C   UNK     0      -4.737  -0.074  -0.790  0.00  0.00           C+0
HETATM   18  C   UNK     0      -5.697  -1.158  -0.336  0.00  0.00           C+0
HETATM   19  O   UNK     0      -4.513  -0.082  -2.145  0.00  0.00           O+0
HETATM   20  C   UNK     0      -2.228   0.325  -0.702  0.00  0.00           C+0
HETATM   21  C   UNK     0      -1.580   1.555  -0.210  0.00  0.00           C+0
HETATM   22  H   UNK     0       6.788  -1.050   1.196  0.00  0.00           H+0
HETATM   23  H   UNK     0       7.398   0.507   0.578  0.00  0.00           H+0
HETATM   24  H   UNK     0       7.370  -0.861  -0.549  0.00  0.00           H+0
HETATM   25  H   UNK     0       5.386   1.755   1.133  0.00  0.00           H+0
HETATM   26  H   UNK     0       3.380   1.905  -1.054  0.00  0.00           H+0
HETATM   27  H   UNK     0       2.934   1.435   1.925  0.00  0.00           H+0
HETATM   28  H   UNK     0       1.225  -3.170   0.342  0.00  0.00           H+0
HETATM   29  H   UNK     0      -3.507   0.121   1.046  0.00  0.00           H+0
HETATM   30  H   UNK     0      -5.213   0.892  -0.521  0.00  0.00           H+0
HETATM   31  H   UNK     0      -6.695  -0.874  -0.764  0.00  0.00           H+0
HETATM   32  H   UNK     0      -5.369  -2.149  -0.666  0.00  0.00           H+0
HETATM   33  H   UNK     0      -5.790  -1.059   0.767  0.00  0.00           H+0
HETATM   34  H   UNK     0      -4.748   0.777  -2.586  0.00  0.00           H+0
HETATM   35  H   UNK     0      -2.197   0.118  -1.785  0.00  0.00           H+0
HETATM   36  H   UNK     0      -1.466   2.277  -1.015  0.00  0.00           H+0
HETATM   37  H   UNK     0      -2.109   1.935   0.682  0.00  0.00           H+0
CONECT    1    2   22   23   24                                             
CONECT    2    1    3    4                                                  
CONECT    3    2                                                            
CONECT    4    2    5   25                                                  
CONECT    5    4    6   26                                                  
CONECT    6    5    7   27                                                  
CONECT    7    6    8                                                       
CONECT    8    7    9   21                                                  
CONECT    9    8   10   13                                                  
CONECT   10    9   11   12                                                  
CONECT   11   10                                                            
CONECT   12   10   28                                                       
CONECT   13    9   14   20                                                  
CONECT   14   13   15   16                                                  
CONECT   15   14                                                            
CONECT   16   14   17   20   29                                             
CONECT   17   16   18   19   30                                             
CONECT   18   17   31   32   33                                             
CONECT   19   17   34                                                       
CONECT   20   16   21   13   35                                             
CONECT   21   20    8   36   37                                             
CONECT   22    1                                                            
CONECT   23    1                                                            
CONECT   24    1                                                            
CONECT   25    4                                                            
CONECT   26    5                                                            
CONECT   27    6                                                            
CONECT   28   12                                                            
CONECT   29   16                                                            
CONECT   30   17                                                            
CONECT   31   18                                                            
CONECT   32   18                                                            
CONECT   33   18                                                            
CONECT   34   19                                                            
CONECT   35   20                                                            
CONECT   36   21                                                            
CONECT   37   21                                                            
MASTER        0    0    0    0    0    0    0    0   37    0   76    0
END

RDKit          3D

37 38  0  0  0  0  0  0  0  0999 V2000
    6.8091   -0.3993    0.3046 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4862    0.0360   -0.1584 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8775   -0.6158   -1.0416 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8957    1.1960    0.3945 N   0  0  0  0  0  0  0  0  0  0  0  0
    3.6177    1.6319   -0.0407 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6394    1.7045    0.8916 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0543    2.2278    0.4357 S   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1898    1.0129    0.2175 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2559   -0.2867    0.3306 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8241   -1.1709    0.7162 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9602   -0.8337    0.9936 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5571   -2.5492    0.7825 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5757   -0.7600    0.0169 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7458   -1.4809   -0.1313 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1183   -2.6647   -0.3008 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4687   -0.1749    0.0020 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.7369   -0.0738   -0.7904 C   0  0  2  0  0  0  0  0  0  0  0  0
   -5.6975   -1.1579   -0.3357 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5125   -0.0816   -2.1451 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2280    0.3246   -0.7015 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.5804    1.5548   -0.2097 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.7877   -1.0500    1.1961 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.3981    0.5074    0.5782 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.3703   -0.8609   -0.5486 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3864    1.7548    1.1326 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3797    1.9054   -1.0537 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9345    1.4345    1.9251 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2251   -3.1700    0.3424 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5067    0.1214    1.0463 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2131    0.8921   -0.5214 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.6948   -0.8736   -0.7644 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3686   -2.1489   -0.6661 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7905   -1.0587    0.7669 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7481    0.7771   -2.5860 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1968    0.1179   -1.7849 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4663    2.2772   -1.0153 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1089    1.9353    0.6820 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  2  0
  2  4  1  0
  4  5  1  0
  5  6  2  0
  6  7  1  0
  7  8  1  0
  8  9  2  0
  9 10  1  0
 10 11  2  0
 10 12  1  0
  9 13  1  0
 13 14  1  0
 14 15  2  0
 14 16  1  0
 16 17  1  0
 17 18  1  0
 17 19  1  0
 16 20  1  0
 20 21  1  0
 21  8  1  0
 20 13  1  0
  1 22  1  0
  1 23  1  0
  1 24  1  0
  4 25  1  0
  5 26  1  0
  6 27  1  0
 12 28  1  0
 16 29  1  1
 17 30  1  1
 18 31  1  0
 18 32  1  0
 18 33  1  0
 19 34  1  0
 20 35  1  6
 21 36  1  0
 21 37  1  0
M  END

View in JSmol View NMR Assignments

Synonyms

Value	Source
(5R,6S)-3-{[(e)-2-acetamidovinyl]sulfanyl}-6-[(1S)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid	ChEBI
MM22383	ChEBI
(5R,6S)-3-{[(e)-2-acetamidovinyl]sulfanyl}-6-[(1S)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate	Generator
(5R,6S)-3-{[(e)-2-acetamidovinyl]sulphanyl}-6-[(1S)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate	Generator
(5R,6S)-3-{[(e)-2-acetamidovinyl]sulphanyl}-6-[(1S)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid	Generator

Chemical Formula

C₁₃H₁₆N₂O₅S

Average Mass

312.3400 Da

Monoisotopic Mass

312.07799 Da

IUPAC Name

(5R,6S)-3-{[(E)-2-acetamidoethenyl]sulfanyl}-6-[(1S)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

Traditional Name

carbapenem MM22383

CAS Registry Number

Not Available

SMILES

C[C@H](O)[C@@H]1[C@H]2CC(S\C=C\NC(C)=O)=C(N2C1=O)C(O)=O

InChI Identifier

InChI=1S/C13H16N2O5S/c1-6(16)10-8-5-9(21-4-3-14-7(2)17)11(13(19)20)15(8)12(10)18/h3-4,6,8,10,16H,5H2,1-2H3,(H,14,17)(H,19,20)/b4-3+/t6-,8+,10+/m0/s1

InChI Key

PRPNUZWHFGSGRV-RZFSBTTISA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Streptomyces olivaceus	NPAtlas	511786

Chemical Taxonomy

Classification

Not classified

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	0.19	ALOGPS
logP	-2.3	ChemAxon
logS	-2	ALOGPS
pKa (Strongest Acidic)	3.86	ChemAxon
pKa (Strongest Basic)	-2.8	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	5	ChemAxon
Hydrogen Donor Count	3	ChemAxon
Polar Surface Area	106.94 Å²	ChemAxon
Rotatable Bond Count	5	ChemAxon
Refractivity	77.57 m³·mol⁻¹	ChemAxon
Polarizability	31.67 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

NPAtlas ID

NPA018213

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

C00018247

Chemspider ID

26331459

KEGG Compound ID

C17398

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

22824517

PDB ID

Not Available

ChEBI ID

58998

Good Scents ID

Not Available

References

General References

Brown AG, Corbett DF, Eglington AJ, Howarth TT: Structures of olivanic acid derivatives MM 22380, MM 22381, MM 22382 and MM 22383; four new antibiotics isolated from Streptomyces olivaceus. J Antibiot (Tokyo). 1979 Sep;32(9):961-3. doi: 10.7164/antibiotics.32.961. [PubMed:511786 ]
Edwards RG, Dewdney JM, Dobrzanski RJ, Lee D: Immunogenicity and allergenicity studies on two beta-lactam structures, a clavam, clavulanic acid, and a carbapenem: structure-activity relationships. Int Arch Allergy Appl Immunol. 1988;85(2):184-9. doi: 10.1159/000234500. [PubMed:3338858 ]

Showing NP-Card for Mm 22383 (NP0021544)

MOL for NP0021544 (Mm 22383)

3D MOL for NP0021544 (Mm 22383)

3D SDF for NP0021544 (Mm 22383)

3D-SDF for NP0021544 (Mm 22383)

PDB for NP0021544 (Mm 22383)

3D PDB for NP0021544 (Mm 22383)

SMILES for NP0021544 (Mm 22383)

INCHI for NP0021544 (Mm 22383)

Structure for NP0021544 (Mm 22383)

3D Structure for NP0021544 (Mm 22383)