NP-MRD: Showing NP-Card for Izumiphenazine C (NP0009569)

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Record Information

Version

2.0

Created at

2021-01-05 19:11:23 UTC

Updated at

2025-12-21 21:41:03 UTC

NP-MRD ID

NP0009569

Natural Product DOI

https://doi.org/10.57994/1968

Secondary Accession Numbers

None

Natural Product Identification

Common Name

Izumiphenazine C

Provided By

NPAtlas

Description

Izumiphenazine C is found in Streptomyces. Based on a literature review very few articles have been published on Izumiphenazine C.

Structure

MOL 3D MOL SDF 3D SDF PDB SMILES InChI


  Mrv1652306242106363D          

 41 44  0  0  0  0            999 V2000
    0.7354    2.3608    0.1248 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9851    1.0203   -0.3306 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.1402    0.3424    0.1122 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1763   -0.4494    1.2335 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3671   -1.0709    1.5823 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5163   -0.9109    0.8275 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7245   -1.5915    1.2546 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.7684   -1.4276    0.5447 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.8110   -2.3895    2.3601 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.4684   -0.1141   -0.2955 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2908    0.5104   -0.6548 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0753    0.3963   -1.2119 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4626   -0.0463   -2.4777 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4092   -0.6564   -3.3537 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7067   -0.8172   -2.9255 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1232   -0.3840   -1.6637 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4006   -0.5532   -1.2670 N   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7855   -0.1226   -0.0315 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.0894   -0.2892    0.3870 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9966   -0.8993   -0.4669 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.4861    0.1523    1.6549 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6060    0.7610    2.5218 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3122    0.9190    2.0897 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8993    0.4846    0.8289 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6220    0.6520    0.4284 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2395    0.2224   -0.8034 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0612    2.8922   -0.5958 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2283    2.3994    1.1070 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6626    2.9840    0.1826 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2652   -0.5571    1.8043 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3309   -1.6866    2.4825 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6176   -2.4072    2.9764 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3601    0.0180   -0.8922 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2853    1.1284   -1.5398 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5080    0.1019   -2.7798 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0515   -0.9803   -4.3264 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4232   -1.2889   -3.5768 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6694   -1.2023   -1.3694 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.5343   -0.0015    1.9442 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9099    1.1031    3.5014 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5757    1.3976    2.7443 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  7  9  1  0  0  0  0
  6 10  1  0  0  0  0
 10 11  2  0  0  0  0
  2 12  1  0  0  0  0
 12 13  2  0  0  0  0
 13 14  1  0  0  0  0
 14 15  2  0  0  0  0
 15 16  1  0  0  0  0
 16 17  2  0  0  0  0
 17 18  1  0  0  0  0
 18 19  2  0  0  0  0
 19 20  1  0  0  0  0
 19 21  1  0  0  0  0
 21 22  2  0  0  0  0
 22 23  1  0  0  0  0
 23 24  2  0  0  0  0
 24 25  1  0  0  0  0
 25 26  2  0  0  0  0
 11  3  1  0  0  0  0
 26 12  1  0  0  0  0
 26 16  1  0  0  0  0
 24 18  1  0  0  0  0
  1 27  1  0  0  0  0
  1 28  1  0  0  0  0
  1 29  1  0  0  0  0
  4 30  1  0  0  0  0
  5 31  1  0  0  0  0
  9 32  1  0  0  0  0
 10 33  1  0  0  0  0
 11 34  1  0  0  0  0
 13 35  1  0  0  0  0
 14 36  1  0  0  0  0
 15 37  1  0  0  0  0
 20 38  1  0  0  0  0
 21 39  1  0  0  0  0
 22 40  1  0  0  0  0
 23 41  1  0  0  0  0
M  END

     RDKit          3D

 41 44  0  0  0  0  0  0  0  0999 V2000
    0.7354    2.3608    0.1248 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9851    1.0203   -0.3306 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.1402    0.3424    0.1122 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1763   -0.4494    1.2335 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3671   -1.0709    1.5823 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5163   -0.9109    0.8275 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7245   -1.5915    1.2546 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.7684   -1.4276    0.5447 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.8110   -2.3895    2.3601 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.4684   -0.1141   -0.2955 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2908    0.5104   -0.6548 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0753    0.3963   -1.2119 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4626   -0.0463   -2.4777 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4092   -0.6564   -3.3537 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7067   -0.8172   -2.9255 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1232   -0.3840   -1.6637 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4006   -0.5532   -1.2670 N   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7855   -0.1226   -0.0315 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.0894   -0.2892    0.3870 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9966   -0.8993   -0.4669 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.4861    0.1523    1.6549 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6060    0.7610    2.5218 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3122    0.9190    2.0897 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8993    0.4846    0.8289 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6220    0.6520    0.4284 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2395    0.2224   -0.8034 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0612    2.8922   -0.5958 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2283    2.3994    1.1070 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6626    2.9840    0.1826 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2652   -0.5571    1.8043 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3309   -1.6866    2.4825 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6176   -2.4072    2.9764 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3601    0.0180   -0.8922 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2853    1.1284   -1.5398 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5080    0.1019   -2.7798 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0515   -0.9803   -4.3264 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4232   -1.2889   -3.5768 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6694   -1.2023   -1.3694 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.5343   -0.0015    1.9442 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9099    1.1031    3.5014 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5757    1.3976    2.7443 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  2  0
  4  5  1  0
  5  6  2  0
  6  7  1  0
  7  8  2  0
  7  9  1  0
  6 10  1  0
 10 11  2  0
  2 12  1  0
 12 13  2  0
 13 14  1  0
 14 15  2  0
 15 16  1  0
 16 17  2  0
 17 18  1  0
 18 19  2  0
 19 20  1  0
 19 21  1  0
 21 22  2  0
 22 23  1  0
 23 24  2  0
 24 25  1  0
 25 26  2  0
 11  3  1  0
 26 12  1  0
 26 16  1  0
 24 18  1  0
  1 27  1  0
  1 28  1  0
  1 29  1  0
  4 30  1  0
  5 31  1  0
  9 32  1  0
 10 33  1  0
 11 34  1  0
 13 35  1  0
 14 36  1  0
 15 37  1  0
 20 38  1  0
 21 39  1  0
 22 40  1  0
 23 41  1  0
M  END


  Mrv1652306242106363D          

 41 44  0  0  0  0            999 V2000
    0.7354    2.3608    0.1248 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9851    1.0203   -0.3306 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.1402    0.3424    0.1122 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1763   -0.4494    1.2335 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3671   -1.0709    1.5823 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5163   -0.9109    0.8275 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7245   -1.5915    1.2546 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.7684   -1.4276    0.5447 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.8110   -2.3895    2.3601 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.4684   -0.1141   -0.2955 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2908    0.5104   -0.6548 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0753    0.3963   -1.2119 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4626   -0.0463   -2.4777 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4092   -0.6564   -3.3537 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7067   -0.8172   -2.9255 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1232   -0.3840   -1.6637 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4006   -0.5532   -1.2670 N   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7855   -0.1226   -0.0315 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.0894   -0.2892    0.3870 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9966   -0.8993   -0.4669 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.4861    0.1523    1.6549 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6060    0.7610    2.5218 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3122    0.9190    2.0897 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8993    0.4846    0.8289 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6220    0.6520    0.4284 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2395    0.2224   -0.8034 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0612    2.8922   -0.5958 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2283    2.3994    1.1070 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6626    2.9840    0.1826 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2652   -0.5571    1.8043 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3309   -1.6866    2.4825 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6176   -2.4072    2.9764 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3601    0.0180   -0.8922 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2853    1.1284   -1.5398 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5080    0.1019   -2.7798 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0515   -0.9803   -4.3264 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4232   -1.2889   -3.5768 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6694   -1.2023   -1.3694 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.5343   -0.0015    1.9442 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9099    1.1031    3.5014 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5757    1.3976    2.7443 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  7  9  1  0  0  0  0
  6 10  1  0  0  0  0
 10 11  2  0  0  0  0
  2 12  1  0  0  0  0
 12 13  2  0  0  0  0
 13 14  1  0  0  0  0
 14 15  2  0  0  0  0
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 16 17  2  0  0  0  0
 17 18  1  0  0  0  0
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 23 24  2  0  0  0  0
 24 25  1  0  0  0  0
 25 26  2  0  0  0  0
 11  3  1  0  0  0  0
 26 12  1  0  0  0  0
 26 16  1  0  0  0  0
 24 18  1  0  0  0  0
  1 27  1  0  0  0  0
  1 28  1  0  0  0  0
  1 29  1  0  0  0  0
  4 30  1  0  0  0  0
  5 31  1  0  0  0  0
  9 32  1  0  0  0  0
 10 33  1  0  0  0  0
 11 34  1  0  0  0  0
 13 35  1  0  0  0  0
 14 36  1  0  0  0  0
 15 37  1  0  0  0  0
 20 38  1  0  0  0  0
 21 39  1  0  0  0  0
 22 40  1  0  0  0  0
 23 41  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0009569

> <DATABASE_NAME>
NP-MRD

> <SMILES>
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C1=C([H])C([H])=C([H])C2=NC3=C(O[H])C([H])=C([H])C([H])=C3N=C12)C([H])([H])[H]

> <INCHI_IDENTIFIER>
InChI=1S/C20H15N3O3/c1-23(13-10-8-12(9-11-13)20(25)26)16-6-2-4-14-18(16)21-15-5-3-7-17(24)19(15)22-14/h2-11,24H,1H3,(H,25,26)

> <INCHI_KEY>
REOKRAKOSOITAV-UHFFFAOYSA-N

> <FORMULA>
C20H15N3O3

> <MOLECULAR_WEIGHT>
345.358

> <EXACT_MASS>
345.111341355

> <JCHEM_ACCEPTOR_COUNT>
6

> <JCHEM_ATOM_COUNT>
41

> <JCHEM_AVERAGE_POLARIZABILITY>
36.301552099520464

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
2

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
4-[(6-hydroxyphenazin-1-yl)(methyl)amino]benzoic acid

> <ALOGPS_LOGP>
3.60

> <JCHEM_LOGP>
4.077875205333333

> <ALOGPS_LOGS>
-3.91

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA>
8.477402971484675

> <JCHEM_PKA_STRONGEST_ACIDIC>
4.63117962306774

> <JCHEM_PKA_STRONGEST_BASIC>
2.2319179212602167

> <JCHEM_POLAR_SURFACE_AREA>
86.55000000000001

> <JCHEM_REFRACTIVITY>
95.77660000000002

> <JCHEM_ROTATABLE_BOND_COUNT>
3

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
4.20e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
izumiphenazine C

> <JCHEM_VEBER_RULE>
0

$$$$

     RDKit          3D

 41 44  0  0  0  0  0  0  0  0999 V2000
    0.7354    2.3608    0.1248 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9851    1.0203   -0.3306 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.1402    0.3424    0.1122 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1763   -0.4494    1.2335 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3671   -1.0709    1.5823 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5163   -0.9109    0.8275 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7245   -1.5915    1.2546 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.7684   -1.4276    0.5447 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.8110   -2.3895    2.3601 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.4684   -0.1141   -0.2955 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2908    0.5104   -0.6548 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0753    0.3963   -1.2119 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4626   -0.0463   -2.4777 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4092   -0.6564   -3.3537 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7067   -0.8172   -2.9255 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1232   -0.3840   -1.6637 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4006   -0.5532   -1.2670 N   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7855   -0.1226   -0.0315 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.0894   -0.2892    0.3870 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9966   -0.8993   -0.4669 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.4861    0.1523    1.6549 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6060    0.7610    2.5218 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3122    0.9190    2.0897 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8993    0.4846    0.8289 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6220    0.6520    0.4284 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2395    0.2224   -0.8034 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0612    2.8922   -0.5958 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2283    2.3994    1.1070 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6626    2.9840    0.1826 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2652   -0.5571    1.8043 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3309   -1.6866    2.4825 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6176   -2.4072    2.9764 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3601    0.0180   -0.8922 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2853    1.1284   -1.5398 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5080    0.1019   -2.7798 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0515   -0.9803   -4.3264 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4232   -1.2889   -3.5768 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6694   -1.2023   -1.3694 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.5343   -0.0015    1.9442 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9099    1.1031    3.5014 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5757    1.3976    2.7443 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  2  0
  4  5  1  0
  5  6  2  0
  6  7  1  0
  7  8  2  0
  7  9  1  0
  6 10  1  0
 10 11  2  0
  2 12  1  0
 12 13  2  0
 13 14  1  0
 14 15  2  0
 15 16  1  0
 16 17  2  0
 17 18  1  0
 18 19  2  0
 19 20  1  0
 19 21  1  0
 21 22  2  0
 22 23  1  0
 23 24  2  0
 24 25  1  0
 25 26  2  0
 11  3  1  0
 26 12  1  0
 26 16  1  0
 24 18  1  0
  1 27  1  0
  1 28  1  0
  1 29  1  0
  4 30  1  0
  5 31  1  0
  9 32  1  0
 10 33  1  0
 11 34  1  0
 13 35  1  0
 14 36  1  0
 15 37  1  0
 20 38  1  0
 21 39  1  0
 22 40  1  0
 23 41  1  0
M  END

HEADER    PROTEIN                                 24-JUN-21   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   24-JUN-21         0                                  
HETATM    1  C   UNK     0       0.735   2.361   0.125  0.00  0.00           C+0
HETATM    2  N   UNK     0       0.985   1.020  -0.331  0.00  0.00           N+0
HETATM    3  C   UNK     0       2.140   0.342   0.112  0.00  0.00           C+0
HETATM    4  C   UNK     0       2.176  -0.449   1.234  0.00  0.00           C+0
HETATM    5  C   UNK     0       3.367  -1.071   1.582  0.00  0.00           C+0
HETATM    6  C   UNK     0       4.516  -0.911   0.828  0.00  0.00           C+0
HETATM    7  C   UNK     0       5.724  -1.591   1.255  0.00  0.00           C+0
HETATM    8  O   UNK     0       6.768  -1.428   0.545  0.00  0.00           O+0
HETATM    9  O   UNK     0       5.811  -2.389   2.360  0.00  0.00           O+0
HETATM   10  C   UNK     0       4.468  -0.114  -0.296  0.00  0.00           C+0
HETATM   11  C   UNK     0       3.291   0.510  -0.655  0.00  0.00           C+0
HETATM   12  C   UNK     0       0.075   0.396  -1.212  0.00  0.00           C+0
HETATM   13  C   UNK     0       0.463  -0.046  -2.478  0.00  0.00           C+0
HETATM   14  C   UNK     0      -0.409  -0.656  -3.354  0.00  0.00           C+0
HETATM   15  C   UNK     0      -1.707  -0.817  -2.926  0.00  0.00           C+0
HETATM   16  C   UNK     0      -2.123  -0.384  -1.664  0.00  0.00           C+0
HETATM   17  N   UNK     0      -3.401  -0.553  -1.267  0.00  0.00           N+0
HETATM   18  C   UNK     0      -3.785  -0.123  -0.032  0.00  0.00           C+0
HETATM   19  C   UNK     0      -5.089  -0.289   0.387  0.00  0.00           C+0
HETATM   20  O   UNK     0      -5.997  -0.899  -0.467  0.00  0.00           O+0
HETATM   21  C   UNK     0      -5.486   0.152   1.655  0.00  0.00           C+0
HETATM   22  C   UNK     0      -4.606   0.761   2.522  0.00  0.00           C+0
HETATM   23  C   UNK     0      -3.312   0.919   2.090  0.00  0.00           C+0
HETATM   24  C   UNK     0      -2.899   0.485   0.829  0.00  0.00           C+0
HETATM   25  N   UNK     0      -1.622   0.652   0.428  0.00  0.00           N+0
HETATM   26  C   UNK     0      -1.240   0.222  -0.803  0.00  0.00           C+0
HETATM   27  H   UNK     0       0.061   2.892  -0.596  0.00  0.00           H+0
HETATM   28  H   UNK     0       0.228   2.399   1.107  0.00  0.00           H+0
HETATM   29  H   UNK     0       1.663   2.984   0.183  0.00  0.00           H+0
HETATM   30  H   UNK     0       1.265  -0.557   1.804  0.00  0.00           H+0
HETATM   31  H   UNK     0       3.331  -1.687   2.482  0.00  0.00           H+0
HETATM   32  H   UNK     0       6.618  -2.407   2.976  0.00  0.00           H+0
HETATM   33  H   UNK     0       5.360   0.018  -0.892  0.00  0.00           H+0
HETATM   34  H   UNK     0       3.285   1.128  -1.540  0.00  0.00           H+0
HETATM   35  H   UNK     0       1.508   0.102  -2.780  0.00  0.00           H+0
HETATM   36  H   UNK     0      -0.052  -0.980  -4.326  0.00  0.00           H+0
HETATM   37  H   UNK     0      -2.423  -1.289  -3.577  0.00  0.00           H+0
HETATM   38  H   UNK     0      -5.669  -1.202  -1.369  0.00  0.00           H+0
HETATM   39  H   UNK     0      -6.534  -0.002   1.944  0.00  0.00           H+0
HETATM   40  H   UNK     0      -4.910   1.103   3.501  0.00  0.00           H+0
HETATM   41  H   UNK     0      -2.576   1.398   2.744  0.00  0.00           H+0
CONECT    1    2   27   28   29                                             
CONECT    2    1    3   12                                                  
CONECT    3    2    4   11                                                  
CONECT    4    3    5   30                                                  
CONECT    5    4    6   31                                                  
CONECT    6    5    7   10                                                  
CONECT    7    6    8    9                                                  
CONECT    8    7                                                            
CONECT    9    7   32                                                       
CONECT   10    6   11   33                                                  
CONECT   11   10    3   34                                                  
CONECT   12    2   13   26                                                  
CONECT   13   12   14   35                                                  
CONECT   14   13   15   36                                                  
CONECT   15   14   16   37                                                  
CONECT   16   15   17   26                                                  
CONECT   17   16   18                                                       
CONECT   18   17   19   24                                                  
CONECT   19   18   20   21                                                  
CONECT   20   19   38                                                       
CONECT   21   19   22   39                                                  
CONECT   22   21   23   40                                                  
CONECT   23   22   24   41                                                  
CONECT   24   23   25   18                                                  
CONECT   25   24   26                                                       
CONECT   26   25   12   16                                                  
CONECT   27    1                                                            
CONECT   28    1                                                            
CONECT   29    1                                                            
CONECT   30    4                                                            
CONECT   31    5                                                            
CONECT   32    9                                                            
CONECT   33   10                                                            
CONECT   34   11                                                            
CONECT   35   13                                                            
CONECT   36   14                                                            
CONECT   37   15                                                            
CONECT   38   20                                                            
CONECT   39   21                                                            
CONECT   40   22                                                            
CONECT   41   23                                                            
MASTER        0    0    0    0    0    0    0    0   41    0   88    0
END

RDKit          3D

41 44  0  0  0  0  0  0  0  0999 V2000
    0.7354    2.3608    0.1248 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9851    1.0203   -0.3306 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.1402    0.3424    0.1122 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1763   -0.4494    1.2335 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3671   -1.0709    1.5823 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5163   -0.9109    0.8275 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7245   -1.5915    1.2546 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.7684   -1.4276    0.5447 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.8110   -2.3895    2.3601 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.4684   -0.1141   -0.2955 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2908    0.5104   -0.6548 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0753    0.3963   -1.2119 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4626   -0.0463   -2.4777 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4092   -0.6564   -3.3537 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7067   -0.8172   -2.9255 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1232   -0.3840   -1.6637 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4006   -0.5532   -1.2670 N   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7855   -0.1226   -0.0315 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.0894   -0.2892    0.3870 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9966   -0.8993   -0.4669 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.4861    0.1523    1.6549 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6060    0.7610    2.5218 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3122    0.9190    2.0897 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8993    0.4846    0.8289 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6220    0.6520    0.4284 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2395    0.2224   -0.8034 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0612    2.8922   -0.5958 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2283    2.3994    1.1070 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6626    2.9840    0.1826 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2652   -0.5571    1.8043 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3309   -1.6866    2.4825 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6176   -2.4072    2.9764 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3601    0.0180   -0.8922 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2853    1.1284   -1.5398 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5080    0.1019   -2.7798 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0515   -0.9803   -4.3264 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4232   -1.2889   -3.5768 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6694   -1.2023   -1.3694 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.5343   -0.0015    1.9442 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9099    1.1031    3.5014 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5757    1.3976    2.7443 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  2  0
  4  5  1  0
  5  6  2  0
  6  7  1  0
  7  8  2  0
  7  9  1  0
  6 10  1  0
 10 11  2  0
  2 12  1  0
 12 13  2  0
 13 14  1  0
 14 15  2  0
 15 16  1  0
 16 17  2  0
 17 18  1  0
 18 19  2  0
 19 20  1  0
 19 21  1  0
 21 22  2  0
 22 23  1  0
 23 24  2  0
 24 25  1  0
 25 26  2  0
 11  3  1  0
 26 12  1  0
 26 16  1  0
 24 18  1  0
  1 27  1  0
  1 28  1  0
  1 29  1  0
  4 30  1  0
  5 31  1  0
  9 32  1  0
 10 33  1  0
 11 34  1  0
 13 35  1  0
 14 36  1  0
 15 37  1  0
 20 38  1  0
 21 39  1  0
 22 40  1  0
 23 41  1  0
M  END

View in JSmol View NMR Assignments

Synonyms

Value	Source
4-[(6-Hydroxyphenazin-1-yl)(methyl)amino]benzoate	Generator

Chemical Formula

C₂₀H₁₅N₃O₃

Average Mass

345.3580 Da

Monoisotopic Mass

345.11134 Da

IUPAC Name

4-[(6-hydroxyphenazin-1-yl)(methyl)amino]benzoic acid

Traditional Name

izumiphenazine C

CAS Registry Number

Not Available

SMILES

CN(C1=CC=C(C=C1)C(O)=O)C1=CC=CC2=C1N=C1C=CC=C(O)C1=N2

InChI Identifier

InChI=1S/C20H15N3O3/c1-23(13-10-8-12(9-11-13)20(25)26)16-6-2-4-14-18(16)21-15-5-3-7-17(24)19(15)22-14/h2-11,24H,1H3,(H,25,26)

InChI Key

REOKRAKOSOITAV-UHFFFAOYSA-N

Experimental Spectra

Spectrum Type	Description	Depositor Email	Depositor Organization	Depositor	Deposition Date	View
HSQC NMR	[¹H, ¹³C] NMR Spectrum (2D, 600 MHz, C2D6OS, experimental)	saranirathnayake@gmail.com	The University of Queensland	Sarani Kankanamge	2024-03-21	View Spectrum
HMBC NMR	[¹H, ¹³C] NMR Spectrum (2D, 600 MHz, C2D6OS, experimental)	saranirathnayake@gmail.com	The University of Queensland	Sarani Kankanamge	2024-03-21	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, C2D6OS, experimental)	saranirathnayake@gmail.com	The University of Queensland	Sarani Kankanamge	2024-03-21	View Spectrum
COSY NMR	[¹H, ¹H] NMR Spectrum (2D, 600 MHz, C2D6OS, experimental)	saranirathnayake@gmail.com	The University of Queensland	Sarani Kankanamge	2024-03-21	View Spectrum

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Streptomyces	NPAtlas	21090727
Streptomyces virginiae		Not Available

Chemical Taxonomy

Description

This compound belongs to the class of organic compounds known as phenazines and derivatives. These are polycyclic aromatic compounds containing a phenazine moiety, which is a linear tricyclic system that consists of a two benzene rings joined by a pyrazine ring.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Diazanaphthalenes

Sub Class

Benzodiazines

Direct Parent

Phenazines and derivatives

Alternative Parents

Substituents

Phenazine
Alkyldiarylamine
Aminobenzoic acid
Aminobenzoic acid or derivatives
Benzoic acid or derivatives
Benzoic acid
Benzoyl
Tertiary aliphatic/aromatic amine
Aniline or substituted anilines
1-hydroxy-4-unsubstituted benzenoid
1-hydroxy-2-unsubstituted benzenoid
Monocyclic benzene moiety
Pyrazine
Benzenoid
Heteroaromatic compound
Amino acid or derivatives
Tertiary amine
Amino acid
Azacycle
Monocarboxylic acid or derivatives
Carboxylic acid
Carboxylic acid derivative
Hydrocarbon derivative
Organonitrogen compound
Organic oxide
Organopnictogen compound
Amine
Organic oxygen compound
Organooxygen compound
Organic nitrogen compound
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

phenazines (CHEBI:70230 )

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	3.6	ALOGPS
logP	4.08	ChemAxon
logS	-3.9	ALOGPS
pKa (Strongest Acidic)	4.63	ChemAxon
pKa (Strongest Basic)	2.23	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	6	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	86.55 Å²	ChemAxon
Rotatable Bond Count	3	ChemAxon
Refractivity	95.78 m³·mol⁻¹	ChemAxon
Polarizability	36.3 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

NPAtlas ID

NPA014841

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

26390026

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

136054934

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Showing NP-Card for Izumiphenazine C (NP0009569)

MOL for NP0009569 (Izumiphenazine C)

3D MOL for NP0009569 (Izumiphenazine C)

3D SDF for NP0009569 (Izumiphenazine C)

3D-SDF for NP0009569 (Izumiphenazine C)

PDB for NP0009569 (Izumiphenazine C)

3D PDB for NP0009569 (Izumiphenazine C)

SMILES for NP0009569 (Izumiphenazine C)

INCHI for NP0009569 (Izumiphenazine C)

Structure for NP0009569 (Izumiphenazine C)

3D Structure for NP0009569 (Izumiphenazine C)