Record Information |
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Version | 1.0 |
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Created at | 2020-11-23 19:38:13 UTC |
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Updated at | 2021-08-12 19:51:53 UTC |
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NP-MRD ID | NP0002698 |
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Secondary Accession Numbers | None |
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Natural Product Identification |
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Common Name | 3-Methyl-2-oxopentanoic acid |
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Provided By | BMRB |
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Description | (R)-3-methyl-2-oxovaleric acid, also known as (R)-2-oxo-3-methylpentanoate or alpha-oxo-beta-methyl-N-valerate, belongs to the class of organic compounds known as short-chain keto acids and derivatives. These are keto acids with an alkyl chain the contains less than 6 carbon atoms. It was first documented in 1992 (PMID: 1638756). Based on a literature review very few articles have been published on (R)-3-methyl-2-oxovaleric acid (PMID: 17984079) (PMID: 34404060) (PMID: 34404046) (PMID: 34404029) (PMID: 34404018) (PMID: 34404014). |
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Structure | InChI=1S/C6H10O3/c1-3-4(2)5(7)6(8)9/h4H,3H2,1-2H3,(H,8,9)/t4-/m1/s1 |
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Synonyms | Value | Source |
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(3R)-2-oxo-3-Methyl-N-valeric acid | ChEBI | (3R)-2-Oxoisoleucine | ChEBI | (3R)-3-Methyl-2-oxopentanoic acid | ChEBI | (R)-2-oxo-3-Methylpentanoate | ChEBI | (R)-2-oxo-3-Methylpentanoic acid | ChEBI | (R)-OMV | ChEBI | alpha-oxo-beta-Methyl-N-valeric acid | ChEBI | alpha-oxo-beta-Methylvaleric acid | ChEBI | (3R)-2-oxo-3-Methyl-N-valerate | Generator | (3R)-3-Methyl-2-oxopentanoate | Generator | a-oxo-b-Methyl-N-valerate | Generator | a-oxo-b-Methyl-N-valeric acid | Generator | alpha-oxo-beta-Methyl-N-valerate | Generator | Α-oxo-β-methyl-N-valerate | Generator | Α-oxo-β-methyl-N-valeric acid | Generator | a-oxo-b-Methylvalerate | Generator | a-oxo-b-Methylvaleric acid | Generator | alpha-oxo-beta-Methylvalerate | Generator | Α-oxo-β-methylvalerate | Generator | Α-oxo-β-methylvaleric acid | Generator | (R)-3-Methyl-2-oxovalerate | Generator | 2oxo-3R-Methyl-pentanoate | Generator |
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Chemical Formula | C6H10O3 |
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Average Mass | 130.1430 Da |
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Monoisotopic Mass | 130.06299 Da |
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IUPAC Name | (3R)-3-methyl-2-oxopentanoic acid |
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Traditional Name | (R)-omv |
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CAS Registry Number | Not Available |
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SMILES | CC[C@@H](C)C(=O)C(O)=O |
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InChI Identifier | InChI=1S/C6H10O3/c1-3-4(2)5(7)6(8)9/h4H,3H2,1-2H3,(H,8,9)/t4-/m1/s1 |
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InChI Key | JVQYSWDUAOAHFM-SCSAIBSYSA-N |
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Experimental Spectra |
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| Spectrum Type | Description | Depositor Email | Depositor Organization | Depositor | Deposition Date | View |
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1D NMR | 1H NMR Spectrum (1D, 500 MHz, D2O, simulated) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 500 MHz, D2O, simulated) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum | 1D NMR | 13C NMR Spectrum (1D, 500 MHz, D2O, experimental) | Wishart Lab | Wishart Lab | David Wishart | 2021-06-20 | View Spectrum |
| Predicted Spectra |
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| Not Available | Chemical Shift Submissions |
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| Not Available | Species |
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Species of Origin | Not Available |
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Chemical Taxonomy |
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Description | Belongs to the class of organic compounds known as short-chain keto acids and derivatives. These are keto acids with an alkyl chain the contains less than 6 carbon atoms. |
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Kingdom | Organic compounds |
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Super Class | Organic acids and derivatives |
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Class | Keto acids and derivatives |
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Sub Class | Short-chain keto acids and derivatives |
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Direct Parent | Short-chain keto acids and derivatives |
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Alternative Parents | |
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Substituents | - Branched fatty acid
- Methyl-branched fatty acid
- Short-chain keto acid
- Alpha-keto acid
- Fatty acyl
- Alpha-hydroxy ketone
- Ketone
- Carboxylic acid derivative
- Carboxylic acid
- Monocarboxylic acid or derivatives
- Carbonyl group
- Hydrocarbon derivative
- Organic oxygen compound
- Organooxygen compound
- Organic oxide
- Aliphatic acyclic compound
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Molecular Framework | Aliphatic acyclic compounds |
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External Descriptors | |
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Physical Properties |
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State | Not Available |
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Experimental Properties | Property | Value | Reference |
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Melting Point | Not Available | Not Available | Boiling Point | Not Available | Not Available | Water Solubility | Not Available | Not Available | LogP | Not Available | Not Available |
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Predicted Properties | |
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General References | - Wendel U, Even G, Langenbeck U, Schadewaldt P, Hummel W: Determination of (S)- and (R)-2-oxo-3-methylvaleric acid in plasma of patients with maple syrup urine disease. Clin Chim Acta. 1992 Jun 15;208(1-2):85-91. [PubMed:1638756 ]
- Ulrich EL, Akutsu H, Doreleijers JF, Harano Y, Ioannidis YE, Lin J, Livny M, Mading S, Maziuk D, Miller Z, Nakatani E, Schulte CF, Tolmie DE, Kent Wenger R, Yao H, Markley JL: BioMagResBank. Nucleic Acids Res. 2008 Jan;36(Database issue):D402-8. doi: 10.1093/nar/gkm957. Epub 2007 Nov 4. [PubMed:17984079 ]
- Yu H, Gild P, Pompe RS, Vetterlein MW, Ludwig TA, Soave A, Kolker M, Maurer V, Marks P, Becker A, Punke MA, Fisch M, Rink M, Dahlem R, Meyer CP: Anesthetic Technique (Spinal vs. General Anesthesia) in Holmium Laser Enucleation of the Prostate: Retrospective Analysis of Procedural and Functional Outcomes among 1,159 Patients. Urol Int. 2021 Aug 17:1-8. doi: 10.1159/000517542. [PubMed:34404060 ]
- Al Riyees L, Al Madani W, Firwana N, Balkhy HH, Ferwana M, Alkhudhayri A: Antibiotic Prophylaxis against Surgical Site Infection after Open Hernia Surgery: A Systematic Review and Meta-Analysis. Eur Surg Res. 2021 Aug 17:1-13. doi: 10.1159/000517404. [PubMed:34404046 ]
- Geer MJ, Foucar CE, Devata S, Benitez L, Perissinotti AJ, Marini BL, Bixby D: Clinical Availability of ATRA for Patients With Suspected Acute Promyelocytic Leukemia: Why Guidelines May Not Be Followed. J Natl Compr Canc Netw. 2021 Aug 17. pii: jnccn20455. doi: 10.6004/jnccn.2021.7013. [PubMed:34404029 ]
- Enwemeka CS, Bumah VV, Mokili JL: Pulsed blue light inactivates two strains of human coronavirus. J Photochem Photobiol B. 2021 Aug 8;222:112282. doi: 10.1016/j.jphotobiol.2021.112282. [PubMed:34404018 ]
- Wang Y, Liu X, Yu L, Hong X, Zhao J, Zhu J, Yuan J, Li W, Zhu X: Identification and analysis of novel microRNAs provide insights to reproductive capacity of the cultured Asian yellow pond turtle Mauremys mutica. Comp Biochem Physiol Part D Genomics Proteomics. 2021 Aug 8;40:100890. doi: 10.1016/j.cbd.2021.100890. [PubMed:34404014 ]
- Yang K, Li CY, An JP, Wang DR, Wang X, Wang CK, You CX: The C2H2-type zinc finger transcription factor MdZAT10 negatively regulates drought tolerance in apple. Plant Physiol Biochem. 2021 Aug 10;167:390-399. doi: 10.1016/j.plaphy.2021.08.014. [PubMed:34404010 ]
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