NP-MRD: Showing NP-Card for Isomaltose (NP0001325)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2006-05-22 15:12:19 UTC

Updated at

2024-09-17 15:44:53 UTC

NP-MRD ID

NP0001325

Secondary Accession Numbers

None

Natural Product Identification

Common Name

Isomaltose

Description

Isomaltose is a disaccharide similar to maltose, but with a α-(1-6)-linkage instead of the α-(1-4)-linkage. Both of the sugars are glucose, which is a pyranose sugar. Isomaltose is a reducing sugar. Isomaltose is produced when high maltose syrup is treated with the enzyme transglucosidase (TG) and is one of the major components in the mixture isomaltooligosaccharide. It is a product of the caramelization of glucose. It is a naturally occurring disaccharide. A deficiency of sucrase-isomaltase, an integral protein of the small intestine brush-border membrane responsible for catalyzing the hydrolysis of dietary sucrose and some of the products of starch digestion, results in osmotic diarrhea when the disaccharide is ingested because absorption cannot occur until after hydrolysis produces the component monosaccharides (OMIM: 222800 ). It is particularly suitable as a non-cariogenic sucrose replacement and is favourable in products for diabetics and prediabetic dispositions.

Structure

MOL 3D MOL SDF 3D SDF PDB 3D PDB SMILES InChI

HMDB0002923
     RDKit          3D
Isomaltose
 45 46  0  0  0  0  0  0  0  0999 V2000
   -5.6259    1.2505    0.0246 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4278    1.9364   -0.1638 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3024    0.9620   -0.5392 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.1171    1.6001   -0.7307 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0182    0.9969   -0.0243 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.8143   -0.2446   -0.4143 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.1648   -0.8294   -1.0465 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5834   -0.8321   -0.5467 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.3638   -1.6702   -1.3636 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.6086   -1.9334   -0.8457 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.4169   -2.6584   -1.7136 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.3189   -0.7010   -0.3329 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.2364   -0.6145    1.0435 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.6703    0.5001   -0.9288 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.7154    0.5653   -2.2972 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.2197    0.5319   -0.4728 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.2285    1.0566    0.8023 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5006    1.0212    1.4196 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.4036    0.9008    2.2508 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4233   -0.1881    1.5382 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.0870   -0.2037    2.7566 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3201   -0.2183    0.3584 C   0  0  2  0  0  0  0  0  0  0  0  0
   -3.1714   -1.3839   -0.4095 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8510    0.8084   -0.8233 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6070    2.6585   -1.0056 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2177    2.4654    0.7870 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6150    0.5983   -1.5680 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2421    1.7640   -0.1269 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1910   -0.6098   -2.1743 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1049   -1.9567   -1.0962 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6156   -1.2650    0.4499 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.4550   -2.5867    0.0414 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2362   -2.5169   -2.6533 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3844   -0.7745   -0.6803 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.1103   -0.2984    1.3747 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.1503    1.4158   -0.5277 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2600   -0.1179   -2.7185 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.7345    1.2435   -1.1615 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1890    0.3873    1.5210 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0419    1.9616    1.6481 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4742    0.0542    2.7892 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7408   -1.0834    1.4677 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3829   -0.2902    3.4575 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3772   -0.2886    0.7640 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9865   -1.4133   -1.0034 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  4  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  8  9  1  0
  9 10  1  0
 10 11  1  0
 10 12  1  0
 12 13  1  0
 12 14  1  0
 14 15  1  0
 14 16  1  0
 16 17  1  0
  5 18  1  0
 18 19  1  0
 18 20  1  0
 20 21  1  0
 20 22  1  0
 22 23  1  0
 22  3  1  0
 16  8  1  0
  1 24  1  0
  2 25  1  0
  2 26  1  0
  3 27  1  6
  5 28  1  1
  7 29  1  0
  7 30  1  0
  8 31  1  1
 10 32  1  1
 11 33  1  0
 12 34  1  1
 13 35  1  0
 14 36  1  1
 15 37  1  0
 16 38  1  6
 17 39  1  0
 18 40  1  1
 19 41  1  0
 20 42  1  1
 21 43  1  0
 22 44  1  1
 23 45  1  0
M  END


  Mrv1652303192023122D          

 23 24  0  0  0  0            999 V2000
 9998.8937 9998.8296    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 9999.6084 9999.2415    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
10001.037110000.0673    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
10002.4700 9999.2415    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
10001.0371 9996.7641    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
10002.4700 9997.5899    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 9997.463410001.3061    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 9996.748310001.7190    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 9997.4634 9998.0038    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 9996.0330 9998.8296    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 9996.033010000.4803    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 9997.463410000.4796    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
 9996.749010000.0671    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
 9996.7490 9999.2421    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
 9997.4634 9998.8297    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
 9998.1778 9999.2421    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
 9998.177810000.0671    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
10001.0385 9999.2414    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
10000.3241 9998.8289    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
10000.3241 9998.0039    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
10001.0385 9997.5915    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
10001.7530 9998.0039    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
10001.7530 9998.8289    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  7  8  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 18 19  1  0  0  0  0
 18 23  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 12 17  1  0  0  0  0
 16 17  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 16  1  1  6  0  0  0
 12  7  1  1  0  0  0
 13 11  1  6  0  0  0
 14 10  1  1  0  0  0
 15  9  1  6  0  0  0
 19  2  1  6  0  0  0
 18  3  1  1  0  0  0
 23  4  1  6  0  0  0
 22  6  1  1  0  0  0
 21  5  1  6  0  0  0
M  END
> <DATABASE_ID>
NP0001325

> <DATABASE_NAME>
NP-MRD

> <SMILES>
OC[C@H]1O[C@H](OC[C@H]2O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

> <INCHI_IDENTIFIER>
InChI=1S/C12H22O11/c13-1-3-5(14)8(17)10(19)12(23-3)21-2-4-6(15)7(16)9(18)11(20)22-4/h3-20H,1-2H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12+/m1/s1

> <INCHI_KEY>
DLRVVLDZNNYCBX-BTLHAWITSA-N

> <FORMULA>
C12H22O11

> <MOLECULAR_WEIGHT>
342.2965

> <EXACT_MASS>
342.116211546

> <JCHEM_ACCEPTOR_COUNT>
11

> <JCHEM_ATOM_COUNT>
45

> <JCHEM_AVERAGE_POLARIZABILITY>
31.045311106176957

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
8

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2R,3R,4S,5S,6R)-6-({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxane-2,3,4,5-tetrol

> <ALOGPS_LOGP>
-3.00

> <JCHEM_LOGP>
-4.703374863666666

> <ALOGPS_LOGS>
0.17

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
12.133081366054801

> <JCHEM_PKA_STRONGEST_ACIDIC>
11.248198780146973

> <JCHEM_PKA_STRONGEST_BASIC>
-2.981083422322401

> <JCHEM_POLAR_SURFACE_AREA>
189.52999999999997

> <JCHEM_REFRACTIVITY>
68.3367

> <JCHEM_ROTATABLE_BOND_COUNT>
4

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
5.11e+02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(2R,3R,4S,5S,6R)-6-({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxane-2,3,4,5-tetrol

> <JCHEM_VEBER_RULE>
0

$$$$

HMDB0002923
     RDKit          3D
Isomaltose
 45 46  0  0  0  0  0  0  0  0999 V2000
   -5.6259    1.2505    0.0246 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4278    1.9364   -0.1638 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3024    0.9620   -0.5392 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.1171    1.6001   -0.7307 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0182    0.9969   -0.0243 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.8143   -0.2446   -0.4143 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.1648   -0.8294   -1.0465 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5834   -0.8321   -0.5467 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.3638   -1.6702   -1.3636 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.6086   -1.9334   -0.8457 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.4169   -2.6584   -1.7136 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.3189   -0.7010   -0.3329 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.2364   -0.6145    1.0435 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.6703    0.5001   -0.9288 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.7154    0.5653   -2.2972 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.2197    0.5319   -0.4728 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.2285    1.0566    0.8023 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5006    1.0212    1.4196 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.4036    0.9008    2.2508 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4233   -0.1881    1.5382 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.0870   -0.2037    2.7566 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3201   -0.2183    0.3584 C   0  0  2  0  0  0  0  0  0  0  0  0
   -3.1714   -1.3839   -0.4095 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8510    0.8084   -0.8233 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6070    2.6585   -1.0056 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2177    2.4654    0.7870 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6150    0.5983   -1.5680 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2421    1.7640   -0.1269 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1910   -0.6098   -2.1743 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1049   -1.9567   -1.0962 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6156   -1.2650    0.4499 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.4550   -2.5867    0.0414 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2362   -2.5169   -2.6533 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3844   -0.7745   -0.6803 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.1103   -0.2984    1.3747 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.1503    1.4158   -0.5277 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2600   -0.1179   -2.7185 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.7345    1.2435   -1.1615 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1890    0.3873    1.5210 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0419    1.9616    1.6481 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4742    0.0542    2.7892 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7408   -1.0834    1.4677 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3829   -0.2902    3.4575 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3772   -0.2886    0.7640 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9865   -1.4133   -1.0034 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  4  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  8  9  1  0
  9 10  1  0
 10 11  1  0
 10 12  1  0
 12 13  1  0
 12 14  1  0
 14 15  1  0
 14 16  1  0
 16 17  1  0
  5 18  1  0
 18 19  1  0
 18 20  1  0
 20 21  1  0
 20 22  1  0
 22 23  1  0
 22  3  1  0
 16  8  1  0
  1 24  1  0
  2 25  1  0
  2 26  1  0
  3 27  1  6
  5 28  1  1
  7 29  1  0
  7 30  1  0
  8 31  1  1
 10 32  1  1
 11 33  1  0
 12 34  1  1
 13 35  1  0
 14 36  1  1
 15 37  1  0
 16 38  1  6
 17 39  1  0
 18 40  1  1
 19 41  1  0
 20 42  1  1
 21 43  1  0
 22 44  1  1
 23 45  1  0
M  END

HEADER    PROTEIN                                 19-MAR-20   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   19-MAR-20         0                                  
HETATM    1  O   UNK     0    8664.6028664.482   0.000  0.00  0.00           O+0
HETATM    2  C   UNK     0    8665.9368665.251   0.000  0.00  0.00           C+0
HETATM    3  O   UNK     0    8668.6038666.792   0.000  0.00  0.00           O+0
HETATM    4  O   UNK     0    8671.2778665.251   0.000  0.00  0.00           O+0
HETATM    5  O   UNK     0    8668.6038660.626   0.000  0.00  0.00           O+0
HETATM    6  O   UNK     0    8671.2778662.168   0.000  0.00  0.00           O+0
HETATM    7  C   UNK     0    8661.9328669.105   0.000  0.00  0.00           C+0
HETATM    8  O   UNK     0    8660.5978669.875   0.000  0.00  0.00           O+0
HETATM    9  O   UNK     0    8661.9328662.940   0.000  0.00  0.00           O+0
HETATM   10  O   UNK     0    8659.2628664.482   0.000  0.00  0.00           O+0
HETATM   11  O   UNK     0    8659.2628667.563   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0    8661.9328667.562   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0    8660.5988666.792   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0    8660.5988665.252   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0    8661.9328664.482   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0    8663.2658665.252   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0    8663.2658666.792   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0    8668.6058665.251   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0    8667.2728664.481   0.000  0.00  0.00           C+0
HETATM   20  O   UNK     0    8667.2728662.941   0.000  0.00  0.00           O+0
HETATM   21  C   UNK     0    8668.6058662.171   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0    8669.9398662.941   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0    8669.9398664.481   0.000  0.00  0.00           C+0
CONECT    1    2   16                                                       
CONECT    2    1   19                                                       
CONECT    3   18                                                            
CONECT    4   23                                                            
CONECT    5   21                                                            
CONECT    6   22                                                            
CONECT    7    8   12                                                       
CONECT    8    7                                                            
CONECT    9   15                                                            
CONECT   10   14                                                            
CONECT   11   13                                                            
CONECT   12   13   17    7                                                  
CONECT   13   12   14   11                                                  
CONECT   14   13   15   10                                                  
CONECT   15   14   16    9                                                  
CONECT   16   15   17    1                                                  
CONECT   17   12   16                                                       
CONECT   18   19   23    3                                                  
CONECT   19   18   20    2                                                  
CONECT   20   19   21                                                       
CONECT   21   22   20    5                                                  
CONECT   22   21   23    6                                                  
CONECT   23   18   22    4                                                  
MASTER        0    0    0    0    0    0    0    0   23    0   48    0
END

COMPND    HMDB0002923
HETATM    1  O1  UNL     1      -5.626   1.250   0.025  1.00  0.00           O  
HETATM    2  C1  UNL     1      -4.428   1.936  -0.164  1.00  0.00           C  
HETATM    3  C2  UNL     1      -3.302   0.962  -0.539  1.00  0.00           C  
HETATM    4  O2  UNL     1      -2.117   1.600  -0.731  1.00  0.00           O  
HETATM    5  C3  UNL     1      -1.018   0.997  -0.024  1.00  0.00           C  
HETATM    6  O3  UNL     1      -0.814  -0.245  -0.414  1.00  0.00           O  
HETATM    7  C4  UNL     1       0.165  -0.829  -1.047  1.00  0.00           C  
HETATM    8  C5  UNL     1       1.583  -0.832  -0.547  1.00  0.00           C  
HETATM    9  O4  UNL     1       2.364  -1.670  -1.364  1.00  0.00           O  
HETATM   10  C6  UNL     1       3.609  -1.933  -0.846  1.00  0.00           C  
HETATM   11  O5  UNL     1       4.417  -2.658  -1.714  1.00  0.00           O  
HETATM   12  C7  UNL     1       4.319  -0.701  -0.333  1.00  0.00           C  
HETATM   13  O6  UNL     1       4.236  -0.615   1.044  1.00  0.00           O  
HETATM   14  C8  UNL     1       3.670   0.500  -0.929  1.00  0.00           C  
HETATM   15  O7  UNL     1       3.715   0.565  -2.297  1.00  0.00           O  
HETATM   16  C9  UNL     1       2.220   0.532  -0.473  1.00  0.00           C  
HETATM   17  O8  UNL     1       2.228   1.057   0.802  1.00  0.00           O  
HETATM   18  C10 UNL     1      -1.501   1.021   1.420  1.00  0.00           C  
HETATM   19  O9  UNL     1      -0.404   0.901   2.251  1.00  0.00           O  
HETATM   20  C11 UNL     1      -2.423  -0.188   1.538  1.00  0.00           C  
HETATM   21  O10 UNL     1      -3.087  -0.204   2.757  1.00  0.00           O  
HETATM   22  C12 UNL     1      -3.320  -0.218   0.358  1.00  0.00           C  
HETATM   23  O11 UNL     1      -3.171  -1.384  -0.410  1.00  0.00           O  
HETATM   24  H1  UNL     1      -5.851   0.808  -0.823  1.00  0.00           H  
HETATM   25  H2  UNL     1      -4.607   2.659  -1.006  1.00  0.00           H  
HETATM   26  H3  UNL     1      -4.218   2.465   0.787  1.00  0.00           H  
HETATM   27  H4  UNL     1      -3.615   0.598  -1.568  1.00  0.00           H  
HETATM   28  H5  UNL     1      -0.242   1.764  -0.127  1.00  0.00           H  
HETATM   29  H6  UNL     1       0.191  -0.610  -2.174  1.00  0.00           H  
HETATM   30  H7  UNL     1      -0.105  -1.957  -1.096  1.00  0.00           H  
HETATM   31  H8  UNL     1       1.616  -1.265   0.450  1.00  0.00           H  
HETATM   32  H9  UNL     1       3.455  -2.587   0.041  1.00  0.00           H  
HETATM   33  H10 UNL     1       4.236  -2.517  -2.653  1.00  0.00           H  
HETATM   34  H11 UNL     1       5.384  -0.774  -0.680  1.00  0.00           H  
HETATM   35  H12 UNL     1       5.110  -0.298   1.375  1.00  0.00           H  
HETATM   36  H13 UNL     1       4.150   1.416  -0.528  1.00  0.00           H  
HETATM   37  H14 UNL     1       4.260  -0.118  -2.719  1.00  0.00           H  
HETATM   38  H15 UNL     1       1.734   1.244  -1.161  1.00  0.00           H  
HETATM   39  H16 UNL     1       2.189   0.387   1.521  1.00  0.00           H  
HETATM   40  H17 UNL     1      -2.042   1.962   1.648  1.00  0.00           H  
HETATM   41  H18 UNL     1      -0.474   0.054   2.789  1.00  0.00           H  
HETATM   42  H19 UNL     1      -1.741  -1.083   1.468  1.00  0.00           H  
HETATM   43  H20 UNL     1      -2.383  -0.290   3.457  1.00  0.00           H  
HETATM   44  H21 UNL     1      -4.377  -0.289   0.764  1.00  0.00           H  
HETATM   45  H22 UNL     1      -3.987  -1.413  -1.003  1.00  0.00           H  
CONECT    1    2   24
CONECT    2    3   25   26
CONECT    3    4   22   27
CONECT    4    5
CONECT    5    6   18   28
CONECT    6    7
CONECT    7    8   29   30
CONECT    8    9   16   31
CONECT    9   10
CONECT   10   11   12   32
CONECT   11   33
CONECT   12   13   14   34
CONECT   13   35
CONECT   14   15   16   36
CONECT   15   37
CONECT   16   17   38
CONECT   17   39
CONECT   18   19   20   40
CONECT   19   41
CONECT   20   21   22   42
CONECT   21   43
CONECT   22   23   44
CONECT   23   45
END

HMDB0002923
     RDKit          3D
Isomaltose
 45 46  0  0  0  0  0  0  0  0999 V2000
   -5.6259    1.2505    0.0246 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4278    1.9364   -0.1638 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3024    0.9620   -0.5392 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.1171    1.6001   -0.7307 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0182    0.9969   -0.0243 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.8143   -0.2446   -0.4143 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.1648   -0.8294   -1.0465 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5834   -0.8321   -0.5467 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.3638   -1.6702   -1.3636 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.6086   -1.9334   -0.8457 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.4169   -2.6584   -1.7136 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.3189   -0.7010   -0.3329 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.2364   -0.6145    1.0435 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.6703    0.5001   -0.9288 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.7154    0.5653   -2.2972 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.2197    0.5319   -0.4728 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.2285    1.0566    0.8023 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5006    1.0212    1.4196 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.4036    0.9008    2.2508 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4233   -0.1881    1.5382 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.0870   -0.2037    2.7566 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3201   -0.2183    0.3584 C   0  0  2  0  0  0  0  0  0  0  0  0
   -3.1714   -1.3839   -0.4095 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8510    0.8084   -0.8233 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6070    2.6585   -1.0056 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2177    2.4654    0.7870 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6150    0.5983   -1.5680 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2421    1.7640   -0.1269 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1910   -0.6098   -2.1743 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1049   -1.9567   -1.0962 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6156   -1.2650    0.4499 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.4550   -2.5867    0.0414 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2362   -2.5169   -2.6533 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3844   -0.7745   -0.6803 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.1103   -0.2984    1.3747 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.1503    1.4158   -0.5277 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2600   -0.1179   -2.7185 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.7345    1.2435   -1.1615 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1890    0.3873    1.5210 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0419    1.9616    1.6481 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4742    0.0542    2.7892 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7408   -1.0834    1.4677 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3829   -0.2902    3.4575 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3772   -0.2886    0.7640 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9865   -1.4133   -1.0034 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  4  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  8  9  1  0
  9 10  1  0
 10 11  1  0
 10 12  1  0
 12 13  1  0
 12 14  1  0
 14 15  1  0
 14 16  1  0
 16 17  1  0
  5 18  1  0
 18 19  1  0
 18 20  1  0
 20 21  1  0
 20 22  1  0
 22 23  1  0
 22  3  1  0
 16  8  1  0
  1 24  1  0
  2 25  1  0
  2 26  1  0
  3 27  1  6
  5 28  1  1
  7 29  1  0
  7 30  1  0
  8 31  1  1
 10 32  1  1
 11 33  1  0
 12 34  1  1
 13 35  1  0
 14 36  1  1
 15 37  1  0
 16 38  1  6
 17 39  1  0
 18 40  1  1
 19 41  1  0
 20 42  1  1
 21 43  1  0
 22 44  1  1
 23 45  1  0
M  END

View in JSmol View NMR Assignments

Synonyms

Value	Source
6-O-alpha-D-Glucopyranosyl-D-glucose	HMDB
6-O-alpha-D-Glucopyranosyl-beta-D-glucopyranose	HMDB
6-O-Α-D-glucopyranosyl-D-glucose	HMDB
6-O-Α-D-glucopyranosyl-β-D-glucopyranose	HMDB
D-Isomaltose	HMDB
beta-D-Isomaltose	HMDB
beta-Isomaltose	HMDB
Β-D-isomaltose	HMDB
Β-isomaltose	HMDB
Isomaltose	HMDB

Chemical Formula

C₁₂H₂₂O₁₁

Average Mass

342.2965 Da

Monoisotopic Mass

342.11621 Da

IUPAC Name

(2R,3R,4S,5S,6R)-6-({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxane-2,3,4,5-tetrol

Traditional Name

(2R,3R,4S,5S,6R)-6-({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxane-2,3,4,5-tetrol

CAS Registry Number

499-40-1

SMILES

OC[C@H]1O[C@H](OC[C@H]2O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI Identifier

InChI=1S/C12H22O11/c13-1-3-5(14)8(17)10(19)12(23-3)21-2-4-6(15)7(16)9(18)11(20)22-4/h3-20H,1-2H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12+/m1/s1

InChI Key

DLRVVLDZNNYCBX-BTLHAWITSA-N

Experimental Spectra

Spectrum Type	Description	Depositor Email	Depositor Organization	Depositor	Deposition Date	View
2D NMR	[¹H, ¹³C]-HSQC NMR Spectrum (2D, 600 MHz, H₂O, experimental)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Anas platyrhynchos	FooDB	FooDB
Anatidae	FooDB	FooDB
Anser anser	FooDB	FooDB
Bison bison	FooDB	FooDB
Bos taurus	FooDB	FooDB
Bos taurus X Bison bison	FooDB	FooDB
Bubalus bubalis	FooDB	FooDB
Capra aegagrus hircus	FooDB	FooDB
Cervidae	FooDB	FooDB
Cervus canadensis	FooDB	FooDB
Columba	FooDB	FooDB
Columbidae	FooDB	FooDB
Daphnia pulex	LOTUS Database	35616633
Dromaius novaehollandiae	FooDB	FooDB
Equus caballus	FooDB	FooDB
Eucommia ulmoides	KNApSAcK Database	22123792
Gallus gallus	FooDB	FooDB
Homo sapiens	LOTUS Database	35616633
Lagopus muta	FooDB	FooDB
Leporidae	FooDB	FooDB
Lepus timidus	FooDB	FooDB
Melanitta fusca	FooDB	FooDB
Meleagris gallopavo	FooDB	FooDB
Mus musculus	LOTUS Database	35616633
Numida meleagris	FooDB	FooDB
Odocoileus	FooDB	FooDB
Oryctolagus	FooDB	FooDB
Ovis aries	FooDB	FooDB
Phasianidae	FooDB	FooDB
Phasianus colchicus	FooDB	FooDB
Pogostemon cablin	LOTUS Database	35616633
Struthio camelus	FooDB	FooDB
Sus scrofa	FooDB	FooDB
Sus scrofa domestica	FooDB	FooDB

Species Where Detected

Species Name	Source	Reference
Streptomyces No. 2265	KNApSAcK Database	22123792

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as o-glycosyl compounds. These are glycoside in which a sugar group is bonded through one carbon to another group via a O-glycosidic bond.

Kingdom

Organic compounds

Super Class

Organic oxygen compounds

Class

Organooxygen compounds

Sub Class

Carbohydrates and carbohydrate conjugates

Direct Parent

O-glycosyl compounds

Alternative Parents

Substituents

O-glycosyl compound
Disaccharide
Oxane
Secondary alcohol
Hemiacetal
Oxacycle
Organoheterocyclic compound
Polyol
Acetal
Hydrocarbon derivative
Primary alcohol
Alcohol
Aliphatic heteromonocyclic compound

Molecular Framework

Aliphatic heteromonocyclic compounds

External Descriptors

Not Available

Physical Properties

State

Solid

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
Water Solubility	511 g/L	ALOGPS
logP	-3	ALOGPS
logP	-4.7	ChemAxon
logS	0.17	ALOGPS
pKa (Strongest Acidic)	11.25	ChemAxon
pKa (Strongest Basic)	-3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	11	ChemAxon
Hydrogen Donor Count	8	ChemAxon
Polar Surface Area	189.53 Å²	ChemAxon
Rotatable Bond Count	4	ChemAxon
Refractivity	68.34 m³·mol⁻¹	ChemAxon
Polarizability	31.05 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

HMDB0002923

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

C00018660

Chemspider ID

9930

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Isomaltose

METLIN ID

Not Available

PubChem Compound

10357

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Kuriyama M, Hiwatari R, Osame M, Igata A: Leucocyte alpha-1,4- and alpha-1,6-glucosidase activities towards oligosaccharides in late onset glycogenosis type II. Tohoku J Exp Med. 1990 Aug;161(4):343-51. [PubMed:2256108 ]
Guddat S, Thevis M, Schanzer W: Identification and quantification of the plasma volume expander dextran in human urine by liquid chromatography-tandem mass spectrometry of enzymatically derived isomaltose. Biomed Chromatogr. 2005 Dec;19(10):743-50. [PubMed:15856492 ]
Vitek V, Vitek K: Chromatography of sugars in body fluids. IV. Separation of isomaltose and lactose in urine by paper chromatography. Biochem Med. 1973 Feb;7(1):119-27. [PubMed:4684081 ]
Martinussen C, Svane MS, Bojsen-Moller KN, Jensen CZ, Kristiansen VB, Bookout AL, Jorgensen SB, Holst JJ, Wewer Albrechtsen NJ, Madsbad S, Kuhre RE: Plasma GDF15 levels are similar between subjects after bariatric surgery and matched controls and are unaffected by meals. Am J Physiol Endocrinol Metab. 2021 Aug 9. doi: 10.1152/ajpendo.00190.2021. [PubMed:34370594 ]
Ichikawa T, Tanaka M, Watanabe T, Zhan S, Watanabe A, Shintani T, Gomi K: Crucial role of the intracellular alpha-glucosidase MalT in the activation of the transcription factor AmyR essential for amylolytic gene expression in Aspergillus oryzae. Biosci Biotechnol Biochem. 2021 Jul 10. pii: 6318857. doi: 10.1093/bbb/zbab125. [PubMed:34245563 ]
Park BR, Park JY, Lee SH, Hong SJ, Jeong JH, Choi JH, Park SY, Park CS, Lee HN, Kim YM: Synthesis of improved long-chain isomaltooligosaccharide, using a novel glucosyltransferase derived from Thermoanaerobacter thermocopriae, with maltodextrin. Enzyme Microb Technol. 2021 Jun;147:109788. doi: 10.1016/j.enzmictec.2021.109788. Epub 2021 Mar 24. [PubMed:33992410 ]
Garcia CA, Gardner JG: Bacterial alpha-diglucoside metabolism: perspectives and potential for biotechnology and biomedicine. Appl Microbiol Biotechnol. 2021 May;105(10):4033-4052. doi: 10.1007/s00253-021-11322-x. Epub 2021 May 7. [PubMed:33961116 ]
Watson A, Simmermaker C, Aung E, Do S, Hackbusch S, Franz AH: NMR analysis and molecular dynamics conformation of alpha-1,6-linear and alpha-1,3-branched isomaltose oligomers as mimetics of alpha-1,6-linked dextran. Carbohydr Res. 2021 May;503:108296. doi: 10.1016/j.carres.2021.108296. Epub 2021 Mar 27. [PubMed:33813322 ]
McCleary BV, McLoughlin C: Measurement of Available Carbohydrates in Cereal and Cereal Products, Dairy Products, Vegetables, Fruit and Related Food Products and Animal Feeds: First Action 2020.07. J AOAC Int. 2021 Feb 5. pii: 6129026. doi: 10.1093/jaoacint/qsab019. [PubMed:33576408 ]

Showing NP-Card for Isomaltose (NP0001325)

MOL for NP0001325 (Isomaltose)

3D MOL for NP0001325 (Isomaltose)

3D SDF for NP0001325 (Isomaltose)

3D-SDF for NP0001325 (Isomaltose)

PDB for NP0001325 (Isomaltose)

3D PDB for NP0001325 (Isomaltose)

SMILES for NP0001325 (Isomaltose)

INCHI for NP0001325 (Isomaltose)

Structure for NP0001325 (Isomaltose)

3D Structure for NP0001325 (Isomaltose)