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Record Information
Version1.0
Created at2007-01-22 22:44:31 UTC
Updated at2022-01-06 17:27:41 UTC
NP-MRD IDNP0000460
Secondary Accession NumbersNone
Natural Product Identification
Common NameKaempferol
DescriptionKaempferol, also known as rhamnolutein or c.I. 75640, Belongs to the class of organic compounds known as flavonols. Flavonols are compounds that contain a flavone (2-phenyl-1-benzopyran-4-one) backbone carrying a hydroxyl group at the 3-position. Thus, kaempferol is considered to be a flavonoid molecule. A tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 5, 7 and 4'. Kaempferol is a very hydrophobic molecule, practically insoluble in water, and relatively neutral. Kaempferol exists in all eukaryotes, ranging from yeast to humans. Kaempferol is a bitter tasting compound. Kaempferol is found, on average, in the highest concentration within a few different foods, such as saffrons, capers, and cumins and in a lower concentration in lovages, endives, and cloves. Kaempferol has also been detected, but not quantified, in several different foods, such as shallots, pine nuts, feijoa, kombus, and chicory leaves. This could make kaempferol a potential biomarker for the consumption of these foods. Kaempferol is a potentially toxic compound.
Structure
Thumb
Synonyms
ValueSource
3,4',5,7-TetrahydroxyflavoneChEBI
4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-5,7,4'-trihydroxyflavonolChEBI
5,7,4'-TrihydroxyflavonolChEBI
C.I. 75640ChEBI
CampherolChEBI
Indigo yellowChEBI
KaempherolChEBI
KampherolChEBI
KempferolChEBI
NimbecetinChEBI
PelargidenolonChEBI
PopulnetinChEBI
RhamnoluteinChEBI
RhamnolutinChEBI
RobigeninChEBI
SwartziolChEBI
TrifolitinChEBI
3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-oneKegg
3,4',5,7-Tetrahydroxy-flavone (7ci,8ci)HMDB
3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-oneHMDB
KampferolHMDB
3,4’,5,7-tetrahydroxyflavoneHMDB
3,5,7,4'-TetrahydroxyflavoneHMDB
3,5,7,4’-tetrahydroxyflavoneHMDB
3'-DeoxyquercetinHMDB
3’-deoxyquercetinHMDB
5,7,4’-trihydroxyflavonolHMDB
KaemferolHMDB
KampcetinHMDB
PelargidenonHMDB
KaempferolPhytoBank
Chemical FormulaC15H10O6
Average Mass286.2363 Da
Monoisotopic Mass286.04774 Da
IUPAC Name3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
Traditional Namekaempferol
CAS Registry Number520-18-3
SMILES
OC1=CC=C(C=C1)C1=C(O)C(=O)C2=C(O1)C=C(O)C=C2O
InChI Identifier
InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,16-18,20H
InChI KeyIYRMWMYZSQPJKC-UHFFFAOYSA-N
Spectra
Spectrum TypeDescriptionDepositor IDDeposition DateView
1D NMR13C NMR Spectrum (1D, 100 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR13C NMR Spectrum (1D, 125 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR13C NMR Spectrum (1D, 150 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR13C NMR Spectrum (1D, 175 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR13C NMR Spectrum (1D, 200 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR13C NMR Spectrum (1D, 225 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR13C NMR Spectrum (1D, 25 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR13C NMR Spectrum (1D, 250 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR13C NMR Spectrum (1D, 50 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR13C NMR Spectrum (1D, 75 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR1H NMR Spectrum (1D, 100 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR1H NMR Spectrum (1D, 1000 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR1H NMR Spectrum (1D, 200 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR1H NMR Spectrum (1D, 300 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR1H NMR Spectrum (1D, 400 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR1H NMR Spectrum (1D, 500 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR1H NMR Spectrum (1D, 600 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR1H NMR Spectrum (1D, 700 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR1H NMR Spectrum (1D, 800 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
1D NMR1H NMR Spectrum (1D, 900 MHz, Methanol-d4, simulated)Wishart Lab2021-06-20View Spectrum
2D NMR[1H, 13C]-HSQC NMR Spectrum (2D, 600 MHz, CD3OD, experimental)Wishart Lab2021-06-20View Spectrum
1D NMR1H NMR Spectrum (1D, 600 MHz, Methanol, simulated)Varshavi.d262021-08-16View Spectrum
1D NMR1H NMR Spectrum (1D, 700 MHz, H2O, simulated)Ahselim2022-01-06View Spectrum
1D NMR1H NMR Spectrum (1D, 700 MHz, H2O, experimental)Ahselim2022-01-06View Spectrum
1D NMR1H NMR Spectrum (1D, 600 MHz, Methanol, simulated)Varshavi.d262021-09-06View Spectrum
1D NMR1H NMR Spectrum (1D, 600 MHz, Methanol, experimental)Varshavi.d262021-09-06View Spectrum
Species
Species of Origin
Species NameSourceReference
Abelmoschus esculentusFooDB
Actinidia chinensisFooDB
Adina cordifolia Roxb.KNApSAcK Database
Adina racemosaKNApSAcK Database
Afzelia bellaKNApSAcK Database
Agaricus bisporusFooDB
Ajuga taiwanensisKNApSAcK Database
Alkanna orientalisKNApSAcK Database
Allium ampeloprasumFooDB
Allium cepaFooDB
Allium cepa L.FooDB
Allium fistulosumFooDB
Allium sativumFooDB
Allium schoenoprasumFooDB
Allium tuberosumFooDB
Alnus japonicaKNApSAcK Database
Aloe veraKNApSAcK Database
AmaranthusFooDB
Ampelopsis brevipedunculataKNApSAcK Database
Anacardium occidentaleFooDB
Ananas comosusFooDB
Anaxagorea luzonensis A.GRAYKNApSAcK Database
Anethum graveolensFooDB
Angelica furcijuga KITAGAWAKNApSAcK Database
Angelica keiskeiFooDB
Anigozanthos pulcherrimusKNApSAcK Database
Anigozanthos rufusKNApSAcK Database
Annona muricataKNApSAcK Database
Antirrhinum majusKNApSAcK Database
Apis mellifera ligusticaKNApSAcK Database
Apium graveolensFooDB
Apium graveolens var. dulceFooDB
Apium graveolens var. rapaceumFooDB
Apium graveolens var. secalinumFooDB
Apocynum venetumKNApSAcK Database
Arabidopsis thalianaKNApSAcK Database
Arachis hypogaeaFooDB
Ardisia colorataKNApSAcK Database
Armoracia rusticanaFooDB
Artemisia annuaKNApSAcK Database
Artemisia dracunculusFooDB
Artocarpus altilisFooDB
Artocarpus heterophyllusFooDB
Ascarina lucidaKNApSAcK Database
Asparagus officinalisKNApSAcK Database
Astragalus membranaceusKNApSAcK Database
Astragalus mongholicusKNApSAcK Database
Astrantia majorKNApSAcK Database
Bertholletia excelsaFooDB
Beta vulgarisFooDB
Beta vulgaris ssp. ciclaFooDB
Betula lentaKNApSAcK Database
Bletilla formosanaKNApSAcK Database
Borago officinalisFooDB
Brassica alboglabraFooDB
Brassica carinata B lineKNApSAcK Database
Brassica carinata Y lineKNApSAcK Database
Brassica junceaFooDB
Brassica napusFooDB
Brassica oleraceaKNApSAcK Database
Brassica oleracea var. botrytisFooDB
Brassica oleracea var. capitataFooDB
Brassica oleracea var. gemmiferaFooDB
Brassica oleracea var. gongylodesFooDB
Brassica oleracea var. italicaFooDB
Brassica oleracea var. sabaudaFooDB
Brassica oleracea var. viridisFooDB
Brassica rapaFooDB
Brassica rapa ssp. chinensisFooDB
Brassica rapa var. pekinensisFooDB
Brassica rapa var. rapaFooDB
Calligonum leucocladumKNApSAcK Database
Calluna vugarisKNApSAcK Database
Caltha palustrisKNApSAcK Database
Camellia sinensisKNApSAcK Database
Cannabis sativaCannabisDB
      Not Available
Capparis himalayensisKNApSAcK Database
Capparis spinosaFooDB
Capsicum annuumKNApSAcK Database
Capsicum annuum var. annuumFooDB
Carica papayaKNApSAcK Database
Carica papaya L.FooDB
Carthamus tinctoriusKNApSAcK Database
Carum carviFooDB
Carya illinoinensisFooDB
Casearia ilicifoliaKNApSAcK Database
Cassia acutifoliaKNApSAcK Database
Cassia angustifoliaKNApSAcK Database
Cassia fistulaKNApSAcK Database
Cassia toraKNApSAcK Database
Castanea sativaFooDB
Casuarina cunninghamiana Miq.KNApSAcK Database
Casuarina equisetifolia L.KNApSAcK Database
Casuarina junghanianaKNApSAcK Database
Casuarina rigidaKNApSAcK Database
Cedrus atlantica Manetii cv.glaucaKNApSAcK Database
Ceratonia siliquaFooDB
Cercis chinensisKNApSAcK Database
Chamaecyparis formosensisKNApSAcK Database
Cheilanthes griseaKNApSAcK Database
Chenopodium muraleKNApSAcK Database
Cichorium endiviaFooDB
Cichorium intybusFooDB
Cinnamomum verumFooDB
Citrullus lanatusFooDB
Citrus aurantifoliaKNApSAcK Database
Citrus aurantiifoliaFooDB
Citrus limonFooDB
Citrus maximaFooDB
Citrus paradisiFooDB
Citrus reticulataFooDB
Citrus X sinensis (L.) Osbeck (pro. sp.)FooDB
Clusia nemorosaKNApSAcK Database
Coccinia grandisKNApSAcK Database
Cocos nuciferaFooDB
Coffea arabica L.FooDB
Coffea canephoraFooDB
Colocasia esculentaFooDB
Colubrina faralaotra subsp.trichocarpa.KNApSAcK Database
Consolida oliverianaKNApSAcK Database
Corchorus olitoriusFooDB
Cordia macleodiiKNApSAcK Database
Coriandrum sativum L.FooDB
Corylus avellanaFooDB
Crocus sativusKNApSAcK Database
Cucumis meloFooDB
Cucumis sativus L.FooDB
CucurbitaFooDB
Cudrania cochinchinensis var. gerontogeaKNApSAcK Database
Cuminum cyminumFooDB
Curcuma longaFooDB
Cuscuta australisKNApSAcK Database
Cuscuta chinensisKNApSAcK Database
Cuscuta japonicaKNApSAcK Database
Cuscuta lupuliformisKNApSAcK Database
Cydonia oblongaFooDB
Daucus carotaFooDB
Daucus carota ssp. sativusFooDB
Davidsonia pruriensKNApSAcK Database
DioscoreaFooDB
Dioscorea bulbifera L.var sativaKNApSAcK Database
Diospyros virginianaFooDB
Diphylleia grayiKNApSAcK Database
Diphylleia sinensisKNApSAcK Database
Elateriospermum taposKNApSAcK Database
Empetrum nigrumFooDB
Ephedra sinicaKNApSAcK Database
Epimedium acuminatumKNApSAcK Database
Epimedium brevicornumKNApSAcK Database
Epimedium dolichostemenKNApSAcK Database
Epimedium fargesiiKNApSAcK Database
Epimedium franchetiiKNApSAcK Database
Epimedium koreanumKNApSAcK Database
Epimedium leishanenseKNApSAcK Database
Epimedium leptorrhizumKNApSAcK Database
Epimedium membranaceumKNApSAcK Database
Epimedium myrianthumKNApSAcK Database
Epimedium pauciflorumKNApSAcK Database
Epimedium pubescensKNApSAcK Database
Epimedium sagittatumKNApSAcK Database
Epimedium stellatumKNApSAcK Database
Epimedium wushanenseKNApSAcK Database
Epimedium zhenbaenseKNApSAcK Database
Epimedium zhushanenseKNApSAcK Database
Equisetum hiemaleKNApSAcK Database
Eriobotrya japonicaFooDB
Eruca vesicaria subsp. SativaFooDB
EucheumaFooDB
Eucommia ulmoidesKNApSAcK Database
Eugenia edulisKNApSAcK Database
Eugenia jambolanaKNApSAcK Database
Eugenia unifloraFooDB
Euphorbia geniculataKNApSAcK Database
Euphorbia lunulataKNApSAcK Database
Euphorbia magalantaKNApSAcK Database
Euphorbia pekinensisKNApSAcK Database
Euphorbia prostrataKNApSAcK Database
Euphorbia virgataKNApSAcK Database
Ficus caricaFooDB
Foeniculum vulgareFooDB
Fragaria x ananassaFooDB
Garcinia bancanaKNApSAcK Database
Garcinia dulcisKNApSAcK Database
Garcinia schomburgkianaKNApSAcK Database
Gaylussacia baccataFooDB
Ginkgo bilobaKNApSAcK Database
Glycine maxKNApSAcK Database
Glycyrrhiza glabraKNApSAcK Database
Glycyrrhiza inflataKNApSAcK Database
Glycyrrhiza uralensisKNApSAcK Database
GossypiumFooDB
Gutierrezia wrightiiKNApSAcK Database
Gynostemma cardiospermumKNApSAcK Database
Haplopappus foliosusKNApSAcK Database
Hedyotis herbaceaKNApSAcK Database
Hedysarum caucasicumKNApSAcK Database
Hedysarum sericeumKNApSAcK Database
Helichrysum graveolenKNApSAcK Database
Hippocratea mucronataKNApSAcK Database
Hippophae rhamnoidesKNApSAcK Database
Humulus lupulusKNApSAcK Database
Hypericum ascyronKNApSAcK Database
Hypericum japonicumKNApSAcK Database
Hypericum perforatumKNApSAcK Database
Hypericum sampsoniiKNApSAcK Database
Illicium verumFooDB
Impatiens capensisKNApSAcK Database
Inula britannicaKNApSAcK Database
Inula britannica var.chinensisKNApSAcK Database
Ipomoea aquaticaFooDB
Ipomoea batatasFooDB
Juglans nigra L.FooDB
Juglans regiaFooDB
Kaempferia galangaKNApSAcK Database
Kummerowia striataKNApSAcK Database
Lactuca sativaFooDB
Laurus nobilisKNApSAcK Database
Laurus nobilis L.FooDB
Lepidium sativumFooDB
Lespedeza virgataKNApSAcK Database
Levisticum officinaleFooDB
Lindera sericeaKNApSAcK Database
Luffa aegyptiacaFooDB
Lupinus albusKNApSAcK Database
Lysimachia capillipesKNApSAcK Database
Lysimachia christinaeKNApSAcK Database
Macadamia tetraphyllaFooDB
Magnolia denudataKNApSAcK Database
Magnolia liliifloraKNApSAcK Database
Malpighia emarginataFooDB
Malus pumilaFooDB
Mangifera indicaKNApSAcK Database
Manihot esculentaFooDB
Matricaria recutitaFooDB
Meconopsis betonicifoliaKNApSAcK Database
Medicago arabicaKNApSAcK Database
Medicago sativaFooDB
Medicago truncatulaKNApSAcK Database
Melissa officinalis L.FooDB
Mentha x piperitaFooDB
Microtropis fokienensisKNApSAcK Database
Momordica charantiaKNApSAcK Database
Morinda citrifoliaKNApSAcK Database
Moringa oleiferaFooDB
Morus nigraFooDB
Musa acuminataKNApSAcK Database
Musa x paradisiacaFooDB
Myrica galeKNApSAcK Database
Myristica fragransFooDB
Nelumbo nuciferaFooDB
Nerium oleanderKNApSAcK Database
Notholaena standleyiKNApSAcK Database
Nymphaea caeruleaKNApSAcK Database
Nymphaea stellataKNApSAcK Database
Ochna beddomeiKNApSAcK Database
Ocimum basilicumFooDB
Oenothera biennisFooDB
Olea europaeaFooDB
Onobrychis vassiltschenkoiKNApSAcK Database
Ononis leiospermaKNApSAcK Database
Ophioglossum petiolatumKNApSAcK Database
OpuntiaFooDB
Origanum majoranaFooDB
Origanum vulgareFooDB
Origanum X majoricumFooDB
Paeonia albifloraKNApSAcK Database
Panax ginseng C.A.Meyer.KNApSAcK Database
PapaverFooDB
Pastinaca sativaFooDB
Pelargonium reniformeKNApSAcK Database
Peltophorum africanumKNApSAcK Database
Persea americanaFooDB
Petasites japonicusFooDB
Petroselinum crispumFooDB
Petunia hybridaKNApSAcK Database
Phaseolus lunatusFooDB
Phaseolus vulgarisFooDB
Phegopteris connectilisKNApSAcK Database
Phellodendron amurense var.wilsoniiKNApSAcK Database
Phoenix dactyliferaFooDB
Photinia melanocarpaFooDB
Phyllanthus emblicaKNApSAcK Database
Phyllanthus urinariaKNApSAcK Database
Phyllogeiton zeyheri Sond.KNApSAcK Database
Picea obovataKNApSAcK Database
PinusFooDB
Pinus sibiricaKNApSAcK Database
Piper nigrum L.FooDB
Piper umbellatumKNApSAcK Database
Pistacia veraFooDB
Pisum sativumFooDB
Podocarpus fasciculusKNApSAcK Database
Portulaca oleraceaFooDB
Posidonia oceanicaKNApSAcK Database
Potentilla chinensisKNApSAcK Database
Prunus armeniacaFooDB
Prunus aviumKNApSAcK Database
Prunus avium L.FooDB
Prunus cerasusFooDB
Prunus domesticaFooDB
Prunus dulcisFooDB
Prunus mahalebKNApSAcK Database
Prunus persicaKNApSAcK Database
Prunus persica var. nucipersicaFooDB
Prunus persica var. persicaFooDB
Psidium cattleianumFooDB
Psidium guajavaFooDB
Pterospermum lanceaefoliumKNApSAcK Database
Punica granatumKNApSAcK Database
Pyrrosia linguaKNApSAcK Database
Pyrus communisFooDB
Raphanus sativusKNApSAcK Database
Raphanus sativus var. longipinnatusFooDB
Raphanus sativus var. sativusFooDB
Reseda muricata C.Presl.KNApSAcK Database
Rhamnus davuricaKNApSAcK Database
Rhamnus dispermaKNApSAcK Database
Rhaponticum carthamoidesKNApSAcK Database
Rhodiola crenulata (HOOK.f.et Thoms.) H.OHBAKNApSAcK Database
Rhodiola kirilowiiKNApSAcK Database
Rhodiola roseaKNApSAcK Database
Rhodiola sachalinensisKNApSAcK Database
Rhodiola sacraKNApSAcK Database
Rhododendron dauricumKNApSAcK Database
Rhododendron huianumKNApSAcK Database
Rhododendron micranthumKNApSAcK Database
RhodophytaFooDB
Rhus parvifloraKNApSAcK Database
Rhus wallichiKNApSAcK Database
Ribes nigrumFooDB
Ribes rubrumFooDB
Ribes uva-crispaFooDB
Rodgersia podophyllaKNApSAcK Database
Rubus arcticusFooDB
Rubus chamaemorusFooDB
Rubus idaeusFooDB
Rubus occidentalisFooDB
RumexFooDB
Sagittaria latifoliaFooDB
Salvia dorriiKNApSAcK Database
Salvia farinaceaKNApSAcK Database
Salvia foliumKNApSAcK Database
Salvia hispanicaFooDB
Salvia officinalisFooDB
Salvia rosmarinusFooDB
Sambucus nigraFooDB
Sambucus nigra L.FooDB
Sapium sebifenumKNApSAcK Database
Satureja subspicataKNApSAcK Database
Saxifraga azizoonKNApSAcK Database
Sedum ewersiiKNApSAcK Database
Semecarpus vitiensisKNApSAcK Database
Silphium perfoliatum L.KNApSAcK Database
Sinoadina racemosaKNApSAcK Database
Sinocrassula indicaKNApSAcK Database
Solanum elaeagnifoliumKNApSAcK Database
Solanum lycopersicumKNApSAcK Database
Solanum lycopersicum var. cerasiformeFooDB
Solanum lycopersicum var. lycopersicumFooDB
Solanum melongenaFooDB
Solanum tuberosumFooDB
Sophora flavescensKNApSAcK Database
Sophora japonicaKNApSAcK Database
Sorbus aucupariaFooDB
Spinacia oleraceaFooDB
Styphnolobium japonicumKNApSAcK Database
Syzygium aromaticumKNApSAcK Database
Syzygium cuminiKNApSAcK Database
Taxus brevifoliaKNApSAcK Database
Taxus fuanaKNApSAcK Database
Taxus yunnanensisKNApSAcK Database
Tetragonia tetragonioidesFooDB
Tetrapanax papyriferusKNApSAcK Database
Theobroma cacaoFooDB
Theobroma grandiflorumKNApSAcK Database
Thesium chinenseKNApSAcK Database
Thevetia peruvianaKNApSAcK Database
Thymus vulgarisFooDB
Toona sinensisKNApSAcK Database
Trigonella foenum-graceumKNApSAcK Database
Trigonella foenum-graecumFooDB
Typha angustifoliaKNApSAcK Database
Urtica dioicaKNApSAcK Database
VacciniumFooDB
Vaccinium angustifoliumFooDB
Vaccinium angustifolium X Vaccinium corymbosumFooDB
Vaccinium corymbosumFooDB
Vaccinium deliciosumFooDB
Vaccinium macrocarponFooDB
Vaccinium myrtillusFooDB
Vaccinium ovalifoliumFooDB
Vaccinium ovatumFooDB
Vaccinium oxycoccosFooDB
Vaccinium parvifoliumFooDB
Vaccinium uliginosumFooDB
Vaccinium vitis-idaeaFooDB
Vicia amoenaKNApSAcK Database
Vicia fabaKNApSAcK Database
Vigna radiataFooDB
Vigna unguiculataFooDB
Vigna unguiculata var. sesquipedalisFooDB
Vismia laurentiiKNApSAcK Database
VitisFooDB
Vitis vinifera L.FooDB
Warburgia stuhlmanniiKNApSAcK Database
Zea maysKNApSAcK Database
Zingiber officinaleFooDB
Chemical Taxonomy
Description Belongs to the class of organic compounds known as flavonols. Flavonols are compounds that contain a flavone (2-phenyl-1-benzopyran-4-one) backbone carrying a hydroxyl group at the 3-position.
KingdomOrganic compounds
Super ClassPhenylpropanoids and polyketides
ClassFlavonoids
Sub ClassFlavones
Direct ParentFlavonols
Alternative Parents
Substituents
  • 3-hydroxyflavone
  • 3-hydroxyflavonoid
  • 4'-hydroxyflavonoid
  • 5-hydroxyflavonoid
  • 7-hydroxyflavonoid
  • Hydroxyflavonoid
  • Chromone
  • Benzopyran
  • 1-benzopyran
  • 1-hydroxy-4-unsubstituted benzenoid
  • 1-hydroxy-2-unsubstituted benzenoid
  • Phenol
  • Pyranone
  • Monocyclic benzene moiety
  • Pyran
  • Benzenoid
  • Heteroaromatic compound
  • Vinylogous acid
  • Polyol
  • Organoheterocyclic compound
  • Oxacycle
  • Organic oxygen compound
  • Organooxygen compound
  • Hydrocarbon derivative
  • Organic oxide
  • Aromatic heteropolycyclic compound
Molecular FrameworkAromatic heteropolycyclic compounds
External Descriptors
Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting Point285 - 287 °CNot Available
Boiling Point582.00 to 583.00 °C. @ 860.00 mm Hg (est)The Good Scents Company Information System
Water Solubility1191 mg/L @ 25 °C (est)The Good Scents Company Information System
LogP2.685 (est)The Good Scents Company Information System
Predicted Properties
PropertyValueSource
Water Solubility0.18 g/LALOGPS
logP10(1.99) g/LALOGPS
logP10(2.46) g/LChemAxon
logS10(-3.2) g/LALOGPS
pKa (Strongest Acidic)6.38ChemAxon
pKa (Strongest Basic)-3.9ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count4ChemAxon
Polar Surface Area107.22 ŲChemAxon
Rotatable Bond Count1ChemAxon
Refractivity74.88 m³·mol⁻¹ChemAxon
Polarizability27.59 ųChemAxon
Number of Rings3ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
HMDB IDHMDB0005801
DrugBank IDDB01852
Phenol Explorer Compound ID290
FoodDB IDFDB000633
KNApSAcK IDC00004565
Chemspider ID4444395
KEGG Compound IDC05903
BioCyc IDCPD1F-90
BiGG IDNot Available
Wikipedia Linkkaempferol
METLIN IDNot Available
PubChem Compound5280863
PDB IDKMP
ChEBI ID28499
Good Scents IDrw1588991
References
General References
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  4. Martini ND, Katerere DR, Eloff JN: Biological activity of five antibacterial flavonoids from Combretum erythrophyllum (Combretaceae). J Ethnopharmacol. 2004 Aug;93(2-3):207-12. doi: 10.1016/j.jep.2004.02.030. [PubMed:15234754 ]
  5. Tang HT, Jiang J, Cao Y, Guan PW, Li H, Zhao YJ, Yu J, Tu PF, Li J, Song YL: [Isomeric discrimination of kaempferol versus luteolin by online energy-resolved mass spectrometry]. Zhongguo Zhong Yao Za Zhi. 2021 Jul;46(14):3599-3604. doi: 10.19540/j.cnki.cjcmm.20210302.301. [PubMed:34402283 ]
  6. Pournaghi N, Khalighi-Sigaroodi F, Safari E, Hajiaghaee R: Bioassay-guided Isolation of Flavonoids from Caesalpinia bonduc (L.) Roxb. and Evaluation of Their Cytotoxicity. Iran J Pharm Res. 2021 Winter;20(1):274-282. doi: 10.22037/ijpr.2020.112557.13824. [PubMed:34400957 ]
  7. Ruiz de la Bastida A, Peiroten A, Langa S, Alvarez I, Arques JL, Landete JM: Metabolism of flavonoids and lignans by lactobacilli and bifidobacteria strains improves the nutritional properties of flaxseed-enriched beverages. Food Res Int. 2021 Sep;147:110488. doi: 10.1016/j.foodres.2021.110488. Epub 2021 May 31. [PubMed:34399484 ]
  8. Ma S, Zheng L, Zheng L, Bian X: Data Mining, Network Pharmacology, and Molecular Docking Explore the Effects of Core Traditional Chinese Medicine Prescriptions in Patients with Rectal Cancer and Qi and Blood Deficiency Syndrome. Evid Based Complement Alternat Med. 2021 Aug 2;2021:1353674. doi: 10.1155/2021/1353674. eCollection 2021. [PubMed:34394377 ]
  9. Khan A, Ali S, Murad W, Hayat K, Siraj S, Jawad M, Khan RA, Uddin J, Al-Harrasi A, Khan A: Phytochemical and pharmacological uses of medicinal plants to treat cancer: A case study from Khyber Pakhtunkhwa, North Pakistan. J Ethnopharmacol. 2021 Aug 12:114437. doi: 10.1016/j.jep.2021.114437. [PubMed:34391861 ]
  10. Patel DK: Pharmacological activities and Therapeutic potential of kaempferitrin in medicine for the treatment of human disorders: A review of medicinal importance and health benefits. Cardiovasc Hematol Disord Drug Targets. 2021 Aug 12. pii: CHDDT-EPUB-117304. doi: 10.2174/1871529X21666210812111931. [PubMed:34387174 ]
  11. Xiao HB, Lu XY, Liu ZK, Luo ZF: Kaempferol inhibits the production of ROS to modulate OPN-alphavbeta3 integrin pathway in HUVECs. J Physiol Biochem. 2016 Jun;72(2):303-13. doi: 10.1007/s13105-016-0479-3. Epub 2016 Mar 21. [PubMed:27000882 ]