Np mrd loader

Showing NP-Card for Glycogen (NP0000229)

Jump To Section:
IdentificationSpectraBioTaxonomyChemoTaxonomyPhysical propertiesLinksReferencesXML
Record Information
Version2.0
Created at2005-11-16 15:48:42 UTC
Updated at2021-08-19 23:57:57 UTC
NP-MRD IDNP0000229
Secondary Accession NumbersNone
Natural Product Identification
Common NameGlycogen
DescriptionGlycogen is a highly-branched polymer of about 30,000 glucose residues. The simplest structure of glycogen is made up of four units of glucose with an approximate molecular weight of 666 daltons. However, large molecules of glycogen can reach molecular weights in the order of 5 million Da. Most of the glucose units are linked together by alpha-1,4 glycosidic bonds, and approximately 1 in 12 glucose residues also form a 1,6 glycosidic bond with a second glucose, resulting in the creation of a branch. Glycogen only has one reducing end and a large number of non-reducing ends with a free hydroxyl group at carbon 4. The glycogen granules contain both glycogen and the enzymes of glycogen synthesis (glycogenesis) and degradation (glycogenolysis). The enzymes are nested between the outer branches of the glycogen molecules and act on the non-reducing ends. Therefore, the many non-reducing end-branches of glycogen facilitate its rapid synthesis and breakdown. In hypoglycemia caused by excessive insulin, liver glycogen levels are high, but the high insulin level prevents the necessary glycogenolysis to take place to maintain normal blood sugar levels. Glucagon is a common treatment for this type of hypoglycemia. Glycogen is a polysaccharide that is the principal storage form of glucose (Glc) in animal cells. Glycogen is found in the form of granules in the cytosol in many cell types. Hepatocytes (liver cells) have the highest concentration of it - up to 8% of the fresh weight in well fed state, or 100 to 120 g in an adult - giving liver a distinctive, 'starchy taste'. In the muscles, glycogen is found in a much lower concentration (1% of the muscle mass), but the total amount exceeds that in liver. Small amounts of glycogen are found in the kidneys, and even smaller amounts in certain glial cells in the brain and white blood cells.
Structure
Thumb
MOL3D MOLSDF3D SDFPDB3D PDBSMILESInChI

MOL for NP0000229 (Glycogen)

 
  Mrv1652305271900142D          
 
 45 48  0  0  1  0            999 V2000
   12.3910  -11.5456    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   12.6900  -10.7275    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   11.6306  -11.9259    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.9391  -12.1409    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   13.5239  -10.5938    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.0257   -9.8861    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.8518  -11.6611    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   13.7257  -12.0046    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   12.6795  -12.9302    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   14.0300  -11.2546    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   12.6002   -9.2996    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.5476  -10.8979    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.3247  -12.3245    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   14.2450  -12.6444    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   14.8691  -11.3647    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.0653   -8.6729    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    9.7190  -10.7931    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    9.5249  -12.2143    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   10.7143  -12.9273    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   15.5115  -10.8534    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   12.3406   -7.8993    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.2550   -8.8250    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    9.2076  -11.4591    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    9.2304  -10.2059    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.0189  -12.8725    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   15.5561  -10.0274    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   16.2222  -11.2809    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   11.8057   -7.2726    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   10.7201   -8.2034    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   10.9928   -9.5288    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.3920  -11.3673    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.4941   -9.7013    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   16.2956   -9.6419    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   14.8487   -9.4365    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   16.9302  -10.9137    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   16.1907  -12.1121    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.9928   -7.4246    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   12.2293   -6.3565    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.9125   -8.3712    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   16.9826  -10.0877    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   15.1030   -8.7687    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   17.6146  -11.3673    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.4290   -6.7979    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.7272   -5.8702    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   17.6860   -9.7153    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  1  3  1  6  0  0  0
  1  4  1  0  0  0  0
  2  5  1  0  0  0  0
  2  6  1  1  0  0  0
  7  3  1  6  0  0  0
  4  8  1  0  0  0  0
  4  9  1  1  0  0  0
  5 10  1  0  0  0  0
  6 11  1  0  0  0  0
  7 12  1  0  0  0  0
  7 13  1  0  0  0  0
  8 14  1  6  0  0  0
 10 15  1  6  0  0  0
 16 11  1  6  0  0  0
 12 17  1  0  0  0  0
 13 18  1  0  0  0  0
 13 19  1  6  0  0  0
 20 15  1  6  0  0  0
 16 21  1  0  0  0  0
 16 22  1  0  0  0  0
 17 23  1  0  0  0  0
 17 24  1  1  0  0  0
 18 25  1  1  0  0  0
 20 26  1  0  0  0  0
 20 27  1  0  0  0  0
 21 28  1  0  0  0  0
 22 29  1  0  0  0  0
 22 30  1  6  0  0  0
 23 31  1  6  0  0  0
 24 32  1  0  0  0  0
 26 33  1  0  0  0  0
 26 34  1  1  0  0  0
 27 35  1  0  0  0  0
 27 36  1  1  0  0  0
 28 37  1  0  0  0  0
 28 38  1  1  0  0  0
 29 39  1  1  0  0  0
 33 40  1  0  0  0  0
 34 41  1  0  0  0  0
 35 42  1  6  0  0  0
 37 43  1  6  0  0  0
 38 44  1  0  0  0  0
 40 45  1  6  0  0  0
  8 10  1  0  0  0  0
 18 23  1  0  0  0  0
 29 37  1  0  0  0  0
 35 40  1  0  0  0  0
M  END
Download

3D MOL for NP0000229 (Glycogen)

HMDB0000757
     RDKit          3D
Glycogen
 87 90  0  0  0  0  0  0  0  0999 V2000
   -0.1394    5.9517   -0.7705 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6274    5.6181   -2.0338 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2124    4.5600   -2.7001 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.2352    3.4339   -1.9760 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7816    2.5624   -1.9204 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.3616    1.2497   -1.6096 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9508    0.9019   -0.4014 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5805   -0.4805    0.0481 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.7597   -0.6917    0.2460 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.3063   -0.0210    1.3426 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.4285   -0.7239    1.7118 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.6315   -0.1150    1.6407 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.4410   -0.8384    0.5544 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.4987   -0.0094   -0.7212 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0856   -0.8136   -1.6887 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.6820   -1.2442    0.9962 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.4723   -0.1705    1.3593 C   0  0  2  0  0  0  0  0  0  0  0  0
    7.7194   -0.7105    1.7489 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.8094    0.5587    2.4839 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.6506    0.5703    3.6195 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.4614   -0.0786    2.8653 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.9553    0.8008    3.8499 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3524   -0.0129    2.5149 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.9896   -0.0358    3.7499 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5228   -1.2641    2.3398 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.1355   -1.6095    3.5175 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4542   -0.9508    1.2027 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.2840   -1.9901    0.8352 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6343   -1.7165    0.8720 C   0  0  1  0  0  0  0  0  0  0  0  0
   -4.2502   -1.9376   -0.3596 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8788   -3.1295   -0.9445 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.8155   -3.4598   -2.0948 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1336   -3.5844   -1.6761 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7241   -4.3030   -0.0633 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.6485   -5.0996   -0.5262 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6289   -4.0610    1.4006 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.1062   -5.1088    2.1726 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2731   -2.7363    1.8086 C   0  0  1  0  0  0  0  0  0  0  0  0
   -4.0637   -2.4534    3.1392 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6288    2.5709   -3.1532 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.2078    1.3184   -3.3993 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8145    2.9945   -4.3295 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.5025    2.9746   -5.5247 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2798    4.3971   -4.1138 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.7902    4.5811   -4.9738 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8930    6.3668   -0.2418 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7636    6.5189   -2.6740 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6367    5.1980   -1.8645 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2580    5.0008   -2.7249 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4629    2.9049   -1.0793 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0647    0.9063   -0.5349 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7301    1.7075    0.3011 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8573   -1.1515   -0.8210 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4640    1.0033    1.0253 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.5021    0.9296    1.2705 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.9150   -1.7885    0.2351 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.4174    0.1602   -1.0009 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.9654    0.9657   -0.5941 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.1634   -1.7587   -1.4110 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6120    0.5090    0.5136 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.7672   -0.7129    2.7250 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.5712    1.6094    2.2280 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6844    1.4570    4.0332 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.7175   -1.0561    3.2839 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.0716    1.7232    3.4576 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3418    0.8425    2.4893 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.9910   -0.9932    4.0439 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2106   -2.0641    2.0220 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6262   -2.3128    3.9537 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0749   -0.0926    1.4801 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8900   -0.7101    1.1945 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8791   -2.9318   -1.4352 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4500   -4.4124   -2.5688 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.8010   -2.7008   -2.8906 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4268   -4.5070   -1.8865 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6247   -4.9702   -0.2204 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2992   -5.6131    0.2336 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5417   -3.9529    1.6628 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5690   -5.7389    1.5362 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3759   -2.7768    1.6584 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6786   -3.1722    3.6690 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4777    3.2958   -2.9821 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9689    1.2362   -2.7458 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.0694    2.3280   -4.3915 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4707    2.9429   -5.3024 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0687    5.1160   -4.3810 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5393    5.0009   -5.8311 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  4  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  8  9  1  0
  9 10  1  0
 10 11  1  0
 11 12  1  0
 12 13  1  0
 13 14  1  0
 14 15  1  0
 13 16  1  0
 16 17  1  0
 17 18  1  0
 17 19  1  0
 19 20  1  0
 19 21  1  0
 21 22  1  0
 10 23  1  0
 23 24  1  0
 23 25  1  0
 25 26  1  0
 25 27  1  0
 27 28  1  0
 28 29  1  0
 29 30  1  0
 30 31  1  0
 31 32  1  0
 32 33  1  0
 31 34  1  0
 34 35  1  0
 34 36  1  0
 36 37  1  0
 36 38  1  0
 38 39  1  0
  5 40  1  0
 40 41  1  0
 40 42  1  0
 42 43  1  0
 42 44  1  0
 44 45  1  0
 44  3  1  0
 27  8  1  0
 38 29  1  0
 21 12  1  0
  1 46  1  0
  2 47  1  0
  2 48  1  0
  3 49  1  6
  5 50  1  1
  7 51  1  0
  7 52  1  0
  8 53  1  6
 10 54  1  6
 12 55  1  6
 13 56  1  6
 14 57  1  0
 14 58  1  0
 15 59  1  0
 17 60  1  6
 18 61  1  0
 19 62  1  6
 20 63  1  0
 21 64  1  1
 22 65  1  0
 23 66  1  1
 24 67  1  0
 25 68  1  6
 26 69  1  0
 27 70  1  1
 29 71  1  1
 31 72  1  6
 32 73  1  0
 32 74  1  0
 33 75  1  0
 34 76  1  1
 35 77  1  0
 36 78  1  1
 37 79  1  0
 38 80  1  1
 39 81  1  0
 40 82  1  1
 41 83  1  0
 42 84  1  6
 43 85  1  0
 44 86  1  6
 45 87  1  0
M  END
Download

3D SDF for NP0000229 (Glycogen)

 
  Mrv1652305271900142D          
 
 45 48  0  0  1  0            999 V2000
   12.3910  -11.5456    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   12.6900  -10.7275    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   11.6306  -11.9259    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.9391  -12.1409    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   13.5239  -10.5938    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.0257   -9.8861    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.8518  -11.6611    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   13.7257  -12.0046    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   12.6795  -12.9302    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   14.0300  -11.2546    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   12.6002   -9.2996    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.5476  -10.8979    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.3247  -12.3245    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   14.2450  -12.6444    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   14.8691  -11.3647    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.0653   -8.6729    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    9.7190  -10.7931    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    9.5249  -12.2143    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   10.7143  -12.9273    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   15.5115  -10.8534    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   12.3406   -7.8993    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.2550   -8.8250    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    9.2076  -11.4591    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    9.2304  -10.2059    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.0189  -12.8725    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   15.5561  -10.0274    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   16.2222  -11.2809    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   11.8057   -7.2726    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   10.7201   -8.2034    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   10.9928   -9.5288    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.3920  -11.3673    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.4941   -9.7013    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   16.2956   -9.6419    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   14.8487   -9.4365    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   16.9302  -10.9137    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   16.1907  -12.1121    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.9928   -7.4246    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   12.2293   -6.3565    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.9125   -8.3712    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   16.9826  -10.0877    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   15.1030   -8.7687    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   17.6146  -11.3673    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.4290   -6.7979    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.7272   -5.8702    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   17.6860   -9.7153    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  1  3  1  6  0  0  0
  1  4  1  0  0  0  0
  2  5  1  0  0  0  0
  2  6  1  1  0  0  0
  7  3  1  6  0  0  0
  4  8  1  0  0  0  0
  4  9  1  1  0  0  0
  5 10  1  0  0  0  0
  6 11  1  0  0  0  0
  7 12  1  0  0  0  0
  7 13  1  0  0  0  0
  8 14  1  6  0  0  0
 10 15  1  6  0  0  0
 16 11  1  6  0  0  0
 12 17  1  0  0  0  0
 13 18  1  0  0  0  0
 13 19  1  6  0  0  0
 20 15  1  6  0  0  0
 16 21  1  0  0  0  0
 16 22  1  0  0  0  0
 17 23  1  0  0  0  0
 17 24  1  1  0  0  0
 18 25  1  1  0  0  0
 20 26  1  0  0  0  0
 20 27  1  0  0  0  0
 21 28  1  0  0  0  0
 22 29  1  0  0  0  0
 22 30  1  6  0  0  0
 23 31  1  6  0  0  0
 24 32  1  0  0  0  0
 26 33  1  0  0  0  0
 26 34  1  1  0  0  0
 27 35  1  0  0  0  0
 27 36  1  1  0  0  0
 28 37  1  0  0  0  0
 28 38  1  1  0  0  0
 29 39  1  1  0  0  0
 33 40  1  0  0  0  0
 34 41  1  0  0  0  0
 35 42  1  6  0  0  0
 37 43  1  6  0  0  0
 38 44  1  0  0  0  0
 40 45  1  6  0  0  0
  8 10  1  0  0  0  0
 18 23  1  0  0  0  0
 29 37  1  0  0  0  0
 35 40  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0000229

> <DATABASE_NAME>
NP-MRD

> <SMILES>
OC[C@H]1O[C@H](OC[C@H]2O[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]3CO)[C@H](O)[C@@H](O)[C@@H]2O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

> <INCHI_IDENTIFIER>
InChI=1S/C24H42O21/c25-1-5-9(28)11(30)16(35)22(41-5)39-4-8-20(45-23-17(36)12(31)10(29)6(2-26)42-23)14(33)18(37)24(43-8)44-19-7(3-27)40-21(38)15(34)13(19)32/h5-38H,1-4H2/t5-,6-,7-,8-,9-,10-,11+,12+,13-,14-,15-,16-,17-,18-,19-,20-,21+,22+,23-,24-/m1/s1

> <INCHI_KEY>
BYSGBSNPRWKUQH-UJDJLXLFSA-N

> <FORMULA>
C24H42O21

> <MOLECULAR_WEIGHT>
666.5777

> <EXACT_MASS>
666.221858406

> <JCHEM_ACCEPTOR_COUNT>
21

> <JCHEM_ATOM_COUNT>
87

> <JCHEM_AVERAGE_POLARIZABILITY>
61.38637800234001

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
14

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2R,3R,4S,5S,6R)-2-{[(2R,3S,4R,5R,6R)-4,5-dihydroxy-6-{[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-2-({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol

> <ALOGPS_LOGP>
-2.67

> <JCHEM_LOGP>
-8.245046155

> <ALOGPS_LOGS>
-0.29

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
11.869173974378574

> <JCHEM_PKA_STRONGEST_ACIDIC>
11.191977452335088

> <JCHEM_PKA_STRONGEST_BASIC>
-3.6786216252270156

> <JCHEM_POLAR_SURFACE_AREA>
347.83000000000004

> <JCHEM_REFRACTIVITY>
133.16330000000002

> <JCHEM_ROTATABLE_BOND_COUNT>
10

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
3.43e+02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(2R,3R,4S,5S,6R)-2-{[(2R,3S,4R,5R,6R)-4,5-dihydroxy-6-{[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-2-({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol

> <JCHEM_VEBER_RULE>
0

$$$$
Download

3D-SDF for NP0000229 (Glycogen)

HMDB0000757
     RDKit          3D
Glycogen
 87 90  0  0  0  0  0  0  0  0999 V2000
   -0.1394    5.9517   -0.7705 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6274    5.6181   -2.0338 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2124    4.5600   -2.7001 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.2352    3.4339   -1.9760 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7816    2.5624   -1.9204 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.3616    1.2497   -1.6096 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9508    0.9019   -0.4014 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5805   -0.4805    0.0481 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.7597   -0.6917    0.2460 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.3063   -0.0210    1.3426 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.4285   -0.7239    1.7118 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.6315   -0.1150    1.6407 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.4410   -0.8384    0.5544 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.4987   -0.0094   -0.7212 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0856   -0.8136   -1.6887 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.6820   -1.2442    0.9962 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.4723   -0.1705    1.3593 C   0  0  2  0  0  0  0  0  0  0  0  0
    7.7194   -0.7105    1.7489 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.8094    0.5587    2.4839 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.6506    0.5703    3.6195 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.4614   -0.0786    2.8653 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.9553    0.8008    3.8499 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3524   -0.0129    2.5149 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.9896   -0.0358    3.7499 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5228   -1.2641    2.3398 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.1355   -1.6095    3.5175 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4542   -0.9508    1.2027 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.2840   -1.9901    0.8352 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6343   -1.7165    0.8720 C   0  0  1  0  0  0  0  0  0  0  0  0
   -4.2502   -1.9376   -0.3596 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8788   -3.1295   -0.9445 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.8155   -3.4598   -2.0948 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1336   -3.5844   -1.6761 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7241   -4.3030   -0.0633 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.6485   -5.0996   -0.5262 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6289   -4.0610    1.4006 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.1062   -5.1088    2.1726 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2731   -2.7363    1.8086 C   0  0  1  0  0  0  0  0  0  0  0  0
   -4.0637   -2.4534    3.1392 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6288    2.5709   -3.1532 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.2078    1.3184   -3.3993 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8145    2.9945   -4.3295 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.5025    2.9746   -5.5247 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2798    4.3971   -4.1138 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.7902    4.5811   -4.9738 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8930    6.3668   -0.2418 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7636    6.5189   -2.6740 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6367    5.1980   -1.8645 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2580    5.0008   -2.7249 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4629    2.9049   -1.0793 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0647    0.9063   -0.5349 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7301    1.7075    0.3011 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8573   -1.1515   -0.8210 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4640    1.0033    1.0253 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.5021    0.9296    1.2705 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.9150   -1.7885    0.2351 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.4174    0.1602   -1.0009 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.9654    0.9657   -0.5941 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.1634   -1.7587   -1.4110 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6120    0.5090    0.5136 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.7672   -0.7129    2.7250 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.5712    1.6094    2.2280 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6844    1.4570    4.0332 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.7175   -1.0561    3.2839 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.0716    1.7232    3.4576 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3418    0.8425    2.4893 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.9910   -0.9932    4.0439 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2106   -2.0641    2.0220 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6262   -2.3128    3.9537 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0749   -0.0926    1.4801 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8900   -0.7101    1.1945 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8791   -2.9318   -1.4352 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4500   -4.4124   -2.5688 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.8010   -2.7008   -2.8906 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4268   -4.5070   -1.8865 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6247   -4.9702   -0.2204 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2992   -5.6131    0.2336 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5417   -3.9529    1.6628 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5690   -5.7389    1.5362 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3759   -2.7768    1.6584 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6786   -3.1722    3.6690 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4777    3.2958   -2.9821 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9689    1.2362   -2.7458 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.0694    2.3280   -4.3915 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4707    2.9429   -5.3024 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0687    5.1160   -4.3810 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5393    5.0009   -5.8311 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  4  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  8  9  1  0
  9 10  1  0
 10 11  1  0
 11 12  1  0
 12 13  1  0
 13 14  1  0
 14 15  1  0
 13 16  1  0
 16 17  1  0
 17 18  1  0
 17 19  1  0
 19 20  1  0
 19 21  1  0
 21 22  1  0
 10 23  1  0
 23 24  1  0
 23 25  1  0
 25 26  1  0
 25 27  1  0
 27 28  1  0
 28 29  1  0
 29 30  1  0
 30 31  1  0
 31 32  1  0
 32 33  1  0
 31 34  1  0
 34 35  1  0
 34 36  1  0
 36 37  1  0
 36 38  1  0
 38 39  1  0
  5 40  1  0
 40 41  1  0
 40 42  1  0
 42 43  1  0
 42 44  1  0
 44 45  1  0
 44  3  1  0
 27  8  1  0
 38 29  1  0
 21 12  1  0
  1 46  1  0
  2 47  1  0
  2 48  1  0
  3 49  1  6
  5 50  1  1
  7 51  1  0
  7 52  1  0
  8 53  1  6
 10 54  1  6
 12 55  1  6
 13 56  1  6
 14 57  1  0
 14 58  1  0
 15 59  1  0
 17 60  1  6
 18 61  1  0
 19 62  1  6
 20 63  1  0
 21 64  1  1
 22 65  1  0
 23 66  1  1
 24 67  1  0
 25 68  1  6
 26 69  1  0
 27 70  1  1
 29 71  1  1
 31 72  1  6
 32 73  1  0
 32 74  1  0
 33 75  1  0
 34 76  1  1
 35 77  1  0
 36 78  1  1
 37 79  1  0
 38 80  1  1
 39 81  1  0
 40 82  1  1
 41 83  1  0
 42 84  1  6
 43 85  1  0
 44 86  1  6
 45 87  1  0
M  END
Download

PDB for NP0000229 (Glycogen)

HEADER    PROTEIN                                 27-MAY-19   NONE
TITLE     NULL                                                        
COMPND    MOLECULE:                                                   
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   27-MAY-19         0                                  
HETATM    1  C   UNK     0      23.130 -21.552   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      23.688 -20.025   0.000  0.00  0.00           C+0
HETATM    3  O   UNK     0      21.710 -22.262   0.000  0.00  0.00           O+0
HETATM    4  C   UNK     0      24.153 -22.663   0.000  0.00  0.00           C+0
HETATM    5  O   UNK     0      25.245 -19.775   0.000  0.00  0.00           O+0
HETATM    6  C   UNK     0      22.448 -18.454   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      20.257 -21.767   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      25.621 -22.409   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0      23.668 -24.136   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0      26.189 -21.009   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0      23.520 -17.359   0.000  0.00  0.00           O+0
HETATM   12  O   UNK     0      19.689 -20.343   0.000  0.00  0.00           O+0
HETATM   13  C   UNK     0      19.273 -23.006   0.000  0.00  0.00           C+0
HETATM   14  O   UNK     0      26.591 -23.603   0.000  0.00  0.00           O+0
HETATM   15  O   UNK     0      27.756 -21.214   0.000  0.00  0.00           O+0
HETATM   16  C   UNK     0      22.522 -16.189   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0      18.142 -20.147   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      17.780 -22.800   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0      20.000 -24.131   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0      28.955 -20.260   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0      23.036 -14.745   0.000  0.00  0.00           O+0
HETATM   22  C   UNK     0      21.009 -16.473   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      17.188 -21.390   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      17.230 -19.051   0.000  0.00  0.00           C+0
HETATM   25  O   UNK     0      16.835 -24.029   0.000  0.00  0.00           O+0
HETATM   26  C   UNK     0      29.038 -18.718   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0      30.281 -21.058   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0      22.037 -13.576   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0      20.011 -15.313   0.000  0.00  0.00           C+0
HETATM   30  O   UNK     0      20.520 -17.787   0.000  0.00  0.00           O+0
HETATM   31  O   UNK     0      15.665 -21.219   0.000  0.00  0.00           O+0
HETATM   32  O   UNK     0      17.722 -18.109   0.000  0.00  0.00           O+0
HETATM   33  O   UNK     0      30.418 -17.998   0.000  0.00  0.00           O+0
HETATM   34  C   UNK     0      27.718 -17.615   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0      31.603 -20.372   0.000  0.00  0.00           C+0
HETATM   36  O   UNK     0      30.223 -22.609   0.000  0.00  0.00           O+0
HETATM   37  C   UNK     0      20.520 -13.859   0.000  0.00  0.00           C+0
HETATM   38  C   UNK     0      22.828 -11.865   0.000  0.00  0.00           C+0
HETATM   39  O   UNK     0      18.503 -15.626   0.000  0.00  0.00           O+0
HETATM   40  C   UNK     0      31.701 -18.830   0.000  0.00  0.00           C+0
HETATM   41  O   UNK     0      28.192 -16.368   0.000  0.00  0.00           O+0
HETATM   42  O   UNK     0      32.881 -21.219   0.000  0.00  0.00           O+0
HETATM   43  O   UNK     0      19.467 -12.689   0.000  0.00  0.00           O+0
HETATM   44  O   UNK     0      21.891 -10.958   0.000  0.00  0.00           O+0
HETATM   45  O   UNK     0      33.014 -18.135   0.000  0.00  0.00           O+0
CONECT    1    2    3    4                                                  
CONECT    2    1    5    6                                                  
CONECT    3    1    7                                                       
CONECT    4    1    8    9                                                  
CONECT    5    2   10                                                       
CONECT    6    2   11                                                       
CONECT    7    3   12   13                                                  
CONECT    8    4   14   10                                                  
CONECT    9    4                                                            
CONECT   10    5   15    8                                                  
CONECT   11    6   16                                                       
CONECT   12    7   17                                                       
CONECT   13    7   18   19                                                  
CONECT   14    8                                                            
CONECT   15   10   20                                                       
CONECT   16   11   21   22                                                  
CONECT   17   12   23   24                                                  
CONECT   18   13   25   23                                                  
CONECT   19   13                                                            
CONECT   20   15   26   27                                                  
CONECT   21   16   28                                                       
CONECT   22   16   29   30                                                  
CONECT   23   17   31   18                                                  
CONECT   24   17   32                                                       
CONECT   25   18                                                            
CONECT   26   20   33   34                                                  
CONECT   27   20   35   36                                                  
CONECT   28   21   37   38                                                  
CONECT   29   22   39   37                                                  
CONECT   30   22                                                            
CONECT   31   23                                                            
CONECT   32   24                                                            
CONECT   33   26   40                                                       
CONECT   34   26   41                                                       
CONECT   35   27   42   40                                                  
CONECT   36   27                                                            
CONECT   37   28   43   29                                                  
CONECT   38   28   44                                                       
CONECT   39   29                                                            
CONECT   40   33   45   35                                                  
CONECT   41   34                                                            
CONECT   42   35                                                            
CONECT   43   37                                                            
CONECT   44   38                                                            
CONECT   45   40                                                            
MASTER        0    0    0    0    0    0    0    0   45    0   96    0
END
Download

3D PDB for NP0000229 (Glycogen)

COMPND    HMDB0000757
HETATM    1  O1  UNL     1      -0.139   5.952  -0.770  1.00  0.00           O  
HETATM    2  C1  UNL     1      -0.627   5.618  -2.034  1.00  0.00           C  
HETATM    3  C2  UNL     1       0.212   4.560  -2.700  1.00  0.00           C  
HETATM    4  O2  UNL     1       0.235   3.434  -1.976  1.00  0.00           O  
HETATM    5  C3  UNL     1      -0.782   2.562  -1.920  1.00  0.00           C  
HETATM    6  O3  UNL     1      -0.362   1.250  -1.610  1.00  0.00           O  
HETATM    7  C4  UNL     1      -0.951   0.902  -0.401  1.00  0.00           C  
HETATM    8  C5  UNL     1      -0.580  -0.481   0.048  1.00  0.00           C  
HETATM    9  O4  UNL     1       0.760  -0.692   0.246  1.00  0.00           O  
HETATM   10  C6  UNL     1       1.306  -0.021   1.343  1.00  0.00           C  
HETATM   11  O5  UNL     1       2.428  -0.724   1.712  1.00  0.00           O  
HETATM   12  C7  UNL     1       3.631  -0.115   1.641  1.00  0.00           C  
HETATM   13  C8  UNL     1       4.441  -0.838   0.554  1.00  0.00           C  
HETATM   14  C9  UNL     1       4.499  -0.009  -0.721  1.00  0.00           C  
HETATM   15  O6  UNL     1       5.086  -0.814  -1.689  1.00  0.00           O  
HETATM   16  O7  UNL     1       5.682  -1.244   0.996  1.00  0.00           O  
HETATM   17  C10 UNL     1       6.472  -0.171   1.359  1.00  0.00           C  
HETATM   18  O8  UNL     1       7.719  -0.710   1.749  1.00  0.00           O  
HETATM   19  C11 UNL     1       5.809   0.559   2.484  1.00  0.00           C  
HETATM   20  O9  UNL     1       6.651   0.570   3.620  1.00  0.00           O  
HETATM   21  C12 UNL     1       4.461  -0.079   2.865  1.00  0.00           C  
HETATM   22  O10 UNL     1       3.955   0.801   3.850  1.00  0.00           O  
HETATM   23  C13 UNL     1       0.352  -0.013   2.515  1.00  0.00           C  
HETATM   24  O11 UNL     1       0.990  -0.036   3.750  1.00  0.00           O  
HETATM   25  C14 UNL     1      -0.523  -1.264   2.340  1.00  0.00           C  
HETATM   26  O12 UNL     1      -1.135  -1.609   3.517  1.00  0.00           O  
HETATM   27  C15 UNL     1      -1.454  -0.951   1.203  1.00  0.00           C  
HETATM   28  O13 UNL     1      -2.284  -1.990   0.835  1.00  0.00           O  
HETATM   29  C16 UNL     1      -3.634  -1.716   0.872  1.00  0.00           C  
HETATM   30  O14 UNL     1      -4.250  -1.938  -0.360  1.00  0.00           O  
HETATM   31  C17 UNL     1      -3.879  -3.130  -0.945  1.00  0.00           C  
HETATM   32  C18 UNL     1      -4.815  -3.460  -2.095  1.00  0.00           C  
HETATM   33  O15 UNL     1      -6.134  -3.584  -1.676  1.00  0.00           O  
HETATM   34  C19 UNL     1      -3.724  -4.303  -0.063  1.00  0.00           C  
HETATM   35  O16 UNL     1      -2.648  -5.100  -0.526  1.00  0.00           O  
HETATM   36  C20 UNL     1      -3.629  -4.061   1.401  1.00  0.00           C  
HETATM   37  O17 UNL     1      -4.106  -5.109   2.173  1.00  0.00           O  
HETATM   38  C21 UNL     1      -4.273  -2.736   1.809  1.00  0.00           C  
HETATM   39  O18 UNL     1      -4.064  -2.453   3.139  1.00  0.00           O  
HETATM   40  C22 UNL     1      -1.629   2.571  -3.153  1.00  0.00           C  
HETATM   41  O19 UNL     1      -2.208   1.318  -3.399  1.00  0.00           O  
HETATM   42  C23 UNL     1      -0.814   2.994  -4.330  1.00  0.00           C  
HETATM   43  O20 UNL     1      -1.502   2.975  -5.525  1.00  0.00           O  
HETATM   44  C24 UNL     1      -0.280   4.397  -4.114  1.00  0.00           C  
HETATM   45  O21 UNL     1       0.790   4.581  -4.974  1.00  0.00           O  
HETATM   46  H1  UNL     1      -0.893   6.367  -0.242  1.00  0.00           H  
HETATM   47  H2  UNL     1      -0.764   6.519  -2.674  1.00  0.00           H  
HETATM   48  H3  UNL     1      -1.637   5.198  -1.865  1.00  0.00           H  
HETATM   49  H4  UNL     1       1.258   5.001  -2.725  1.00  0.00           H  
HETATM   50  H5  UNL     1      -1.463   2.905  -1.079  1.00  0.00           H  
HETATM   51  H6  UNL     1      -2.065   0.906  -0.535  1.00  0.00           H  
HETATM   52  H7  UNL     1      -0.730   1.708   0.301  1.00  0.00           H  
HETATM   53  H8  UNL     1      -0.857  -1.151  -0.821  1.00  0.00           H  
HETATM   54  H9  UNL     1       1.464   1.003   1.025  1.00  0.00           H  
HETATM   55  H10 UNL     1       3.502   0.930   1.270  1.00  0.00           H  
HETATM   56  H11 UNL     1       3.915  -1.788   0.235  1.00  0.00           H  
HETATM   57  H12 UNL     1       3.417   0.160  -1.001  1.00  0.00           H  
HETATM   58  H13 UNL     1       4.965   0.966  -0.594  1.00  0.00           H  
HETATM   59  H14 UNL     1       5.163  -1.759  -1.411  1.00  0.00           H  
HETATM   60  H15 UNL     1       6.612   0.509   0.514  1.00  0.00           H  
HETATM   61  H16 UNL     1       7.767  -0.713   2.725  1.00  0.00           H  
HETATM   62  H17 UNL     1       5.571   1.609   2.228  1.00  0.00           H  
HETATM   63  H18 UNL     1       6.684   1.457   4.033  1.00  0.00           H  
HETATM   64  H19 UNL     1       4.717  -1.056   3.284  1.00  0.00           H  
HETATM   65  H20 UNL     1       4.072   1.723   3.458  1.00  0.00           H  
HETATM   66  H21 UNL     1      -0.342   0.843   2.489  1.00  0.00           H  
HETATM   67  H22 UNL     1       0.991  -0.993   4.044  1.00  0.00           H  
HETATM   68  H23 UNL     1       0.211  -2.064   2.022  1.00  0.00           H  
HETATM   69  H24 UNL     1      -0.626  -2.313   3.954  1.00  0.00           H  
HETATM   70  H25 UNL     1      -2.075  -0.093   1.480  1.00  0.00           H  
HETATM   71  H26 UNL     1      -3.890  -0.710   1.194  1.00  0.00           H  
HETATM   72  H27 UNL     1      -2.879  -2.932  -1.435  1.00  0.00           H  
HETATM   73  H28 UNL     1      -4.450  -4.412  -2.569  1.00  0.00           H  
HETATM   74  H29 UNL     1      -4.801  -2.701  -2.891  1.00  0.00           H  
HETATM   75  H30 UNL     1      -6.427  -4.507  -1.887  1.00  0.00           H  
HETATM   76  H31 UNL     1      -4.625  -4.970  -0.220  1.00  0.00           H  
HETATM   77  H32 UNL     1      -2.299  -5.613   0.234  1.00  0.00           H  
HETATM   78  H33 UNL     1      -2.542  -3.953   1.663  1.00  0.00           H  
HETATM   79  H34 UNL     1      -4.569  -5.739   1.536  1.00  0.00           H  
HETATM   80  H35 UNL     1      -5.376  -2.777   1.658  1.00  0.00           H  
HETATM   81  H36 UNL     1      -3.679  -3.172   3.669  1.00  0.00           H  
HETATM   82  H37 UNL     1      -2.478   3.296  -2.982  1.00  0.00           H  
HETATM   83  H38 UNL     1      -2.969   1.236  -2.746  1.00  0.00           H  
HETATM   84  H39 UNL     1       0.069   2.328  -4.391  1.00  0.00           H  
HETATM   85  H40 UNL     1      -2.471   2.943  -5.302  1.00  0.00           H  
HETATM   86  H41 UNL     1      -1.069   5.116  -4.381  1.00  0.00           H  
HETATM   87  H42 UNL     1       0.539   5.001  -5.831  1.00  0.00           H  
CONECT    1    2   46
CONECT    2    3   47   48
CONECT    3    4   44   49
CONECT    4    5
CONECT    5    6   40   50
CONECT    6    7
CONECT    7    8   51   52
CONECT    8    9   27   53
CONECT    9   10
CONECT   10   11   23   54
CONECT   11   12
CONECT   12   13   21   55
CONECT   13   14   16   56
CONECT   14   15   57   58
CONECT   15   59
CONECT   16   17
CONECT   17   18   19   60
CONECT   18   61
CONECT   19   20   21   62
CONECT   20   63
CONECT   21   22   64
CONECT   22   65
CONECT   23   24   25   66
CONECT   24   67
CONECT   25   26   27   68
CONECT   26   69
CONECT   27   28   70
CONECT   28   29
CONECT   29   30   38   71
CONECT   30   31
CONECT   31   32   34   72
CONECT   32   33   73   74
CONECT   33   75
CONECT   34   35   36   76
CONECT   35   77
CONECT   36   37   38   78
CONECT   37   79
CONECT   38   39   80
CONECT   39   81
CONECT   40   41   42   82
CONECT   41   83
CONECT   42   43   44   84
CONECT   43   85
CONECT   44   45   86
CONECT   45   87
END
Download

SMILES for NP0000229 (Glycogen)

OC[C@H]1O[C@H](OC[C@H]2O[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]3CO)[C@H](O)[C@@H](O)[C@@H]2O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
Download

INCHI for NP0000229 (Glycogen)

InChI=1S/C24H42O21/c25-1-5-9(28)11(30)16(35)22(41-5)39-4-8-20(45-23-17(36)12(31)10(29)6(2-26)42-23)14(33)18(37)24(43-8)44-19-7(3-27)40-21(38)15(34)13(19)32/h5-38H,1-4H2/t5-,6-,7-,8-,9-,10-,11+,12+,13-,14-,15-,16-,17-,18-,19-,20-,21+,22+,23-,24-/m1/s1
Download
View in JSmol
Synonyms
ValueSource
Animal starchHMDB
Liver starchHMDB
LyoglycogenHMDB
PhytoglycogenHMDB
Chemical FormulaC24H42O21
Average Mass666.5777 Da
Monoisotopic Mass666.22186 Da
IUPAC Name(2R,3R,4S,5S,6R)-2-{[(2R,3S,4R,5R,6R)-4,5-dihydroxy-6-{[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-2-({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
Traditional Name(2R,3R,4S,5S,6R)-2-{[(2R,3S,4R,5R,6R)-4,5-dihydroxy-6-{[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-2-({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
CAS Registry Number9005-79-2
SMILES
OC[C@H]1O[C@H](OC[C@H]2O[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]3CO)[C@H](O)[C@@H](O)[C@@H]2O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
InChI Identifier
InChI=1S/C24H42O21/c25-1-5-9(28)11(30)16(35)22(41-5)39-4-8-20(45-23-17(36)12(31)10(29)6(2-26)42-23)14(33)18(37)24(43-8)44-19-7(3-27)40-21(38)15(34)13(19)32/h5-38H,1-4H2/t5-,6-,7-,8-,9-,10-,11+,12+,13-,14-,15-,16-,17-,18-,19-,20-,21+,22+,23-,24-/m1/s1
InChI KeyBYSGBSNPRWKUQH-UJDJLXLFSA-N
Experimental Spectra
Spectrum TypeDescriptionDepositor EmailDepositor OrganizationDepositorDeposition DateView
1D NMR1H NMR Spectrum (1D, 600 MHz, H2O, experimental)Wishart LabWishart LabDavid Wishart2021-06-20View Spectrum
2D NMR[1H, 13C]-HSQC NMR Spectrum (2D, 600 MHz, H2O, experimental)Wishart LabWishart LabDavid Wishart2021-06-20View Spectrum
Predicted Spectra
Not Available
Chemical Shift Submissions
Not Available
Species
Species of Origin
Species NameSourceReference
Aliger gigasLOTUS Database
Anas platyrhynchosFooDB
AnatidaeFooDB
Anser anserFooDB
Bison bisonFooDB
Bos taurusFooDB
Bos taurus X Bison bisonFooDB
Bubalus bubalisFooDB
Capra aegagrus hircusFooDB
CervidaeFooDB
Cervus canadensisFooDB
ColumbaFooDB
ColumbidaeFooDB
Dromaius novaehollandiaeFooDB
Equus caballusFooDB
Gallus gallusFooDB
Lagopus mutaFooDB
LeporidaeFooDB
Lepus timidusFooDB
Melanitta fuscaFooDB
Meleagris gallopavoFooDB
Numida meleagrisFooDB
OdocoileusFooDB
OryctolagusFooDB
Ovis ariesFooDB
PhasianidaeFooDB
Phasianus colchicusFooDB
Struthio camelusFooDB
Sus scrofaFooDB
Sus scrofa domesticaFooDB
Chemical Taxonomy
Description Belongs to the class of organic compounds known as oligosaccharides. These are carbohydrates made up of 3 to 10 monosaccharide units linked to each other through glycosidic bonds.
KingdomOrganic compounds
Super ClassOrganic oxygen compounds
ClassOrganooxygen compounds
Sub ClassCarbohydrates and carbohydrate conjugates
Direct ParentOligosaccharides
Alternative Parents
Substituents
  • Oligosaccharide
  • O-glycosyl compound
  • Glycosyl compound
  • Oxane
  • Secondary alcohol
  • Hemiacetal
  • Oxacycle
  • Organoheterocyclic compound
  • Polyol
  • Acetal
  • Hydrocarbon derivative
  • Primary alcohol
  • Alcohol
  • Aliphatic heteromonocyclic compound
Molecular FrameworkAliphatic heteromonocyclic compounds
External Descriptors
Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting Point270 - 280 °CNot Available
Boiling Point1027.20 °C. @ 760.00 mm Hg (est)The Good Scents Company Information System
Water Solubility1000000 mg/L @ 25 °C (est)The Good Scents Company Information System
LogP-5.590 (est)The Good Scents Company Information System
Predicted Properties
PropertyValueSource
Water Solubility343 g/LALOGPS
logP-2.7ALOGPS
logP-8.2ChemAxon
logS-0.29ALOGPS
pKa (Strongest Acidic)11.19ChemAxon
pKa (Strongest Basic)-3.7ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count21ChemAxon
Hydrogen Donor Count14ChemAxon
Polar Surface Area347.83 ŲChemAxon
Rotatable Bond Count10ChemAxon
Refractivity133.16 m³·mol⁻¹ChemAxon
Polarizability61.39 ųChemAxon
Number of Rings4ChemAxon
BioavailabilityNoChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleYesChemAxon
HMDB IDHMDB0000757
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FoodDB IDFDB022227
KNApSAcK IDNot Available
Chemspider ID388322
KEGG Compound IDC00182
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkGlycogen
METLIN ID160
PubChem Compound439177
PDB IDNot Available
ChEBI ID28087
Good Scents IDrw1233951
References
General References
  1. Zderic TW, Schenk S, Davidson CJ, Byerley LO, Coyle EF: Manipulation of dietary carbohydrate and muscle glycogen affects glucose uptake during exercise when fat oxidation is impaired by beta-adrenergic blockade. Am J Physiol Endocrinol Metab. 2004 Dec;287(6):E1195-201. Epub 2004 Aug 17. [PubMed:15315908 ]
  2. Schaart G, Hesselink RP, Keizer HA, van Kranenburg G, Drost MR, Hesselink MK: A modified PAS stain combined with immunofluorescence for quantitative analyses of glycogen in muscle sections. Histochem Cell Biol. 2004 Aug;122(2):161-9. Epub 2004 Aug 3. [PubMed:15322861 ]
  3. Wee SL, Williams C, Tsintzas K, Boobis L: Ingestion of a high-glycemic index meal increases muscle glycogen storage at rest but augments its utilization during subsequent exercise. J Appl Physiol (1985). 2005 Aug;99(2):707-14. Epub 2005 Apr 14. [PubMed:15831796 ]
  4. Zehnder M, Muelli M, Buchli R, Kuehne G, Boutellier U: Further glycogen decrease during early recovery after eccentric exercise despite a high carbohydrate intake. Eur J Nutr. 2004 Jun;43(3):148-59. Epub 2004 Jan 6. [PubMed:15168037 ]
  5. Koopman R, Manders RJ, Jonkers RA, Hul GB, Kuipers H, van Loon LJ: Intramyocellular lipid and glycogen content are reduced following resistance exercise in untrained healthy males. Eur J Appl Physiol. 2006 Mar;96(5):525-34. Epub 2005 Dec 21. [PubMed:16369816 ]
  6. Jentjens R, Jeukendrup A: Determinants of post-exercise glycogen synthesis during short-term recovery. Sports Med. 2003;33(2):117-44. [PubMed:12617691 ]
  7. Ouwens DM, van der Zon GC, Maassen JA: Modulation of insulin-stimulated glycogen synthesis by Src Homology Phosphatase 2. Mol Cell Endocrinol. 2001 Apr 25;175(1-2):131-40. [PubMed:11325523 ]
  8. Koppersmith DL, Powers JM, Hennigar GR: Angiomatoid neuroblastoma with cytoplasmic glycogen: a case report and histogenetic considerations. Cancer. 1980 Feb;45(3):553-60. [PubMed:7353205 ]
  9. Kohler G, Boutellier U: Glycogen reduction in non-exercising muscle depends on blood lactate concentration. Eur J Appl Physiol. 2004 Aug;92(4-5):548-54. [PubMed:15170570 ]
  10. Crosson SM, Khan A, Printen J, Pessin JE, Saltiel AR: PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance. J Clin Invest. 2003 May;111(9):1423-32. [PubMed:12727934 ]
  11. Dube SN, Nayak BB, Das PK: Effect of foot-electroshock stress on cholinergic activity, tissue glycogen and blood sugar in albino rats. Indian J Physiol Pharmacol. 1978 Jan-Mar;22(1):24-32. [PubMed:567191 ]
  12. Chryssanthopoulos C, Williams C, Nowitz A, Bogdanis G: Skeletal muscle glycogen concentration and metabolic responses following a high glycaemic carbohydrate breakfast. J Sports Sci. 2004 Nov-Dec;22(11-12):1065-71. [PubMed:15801500 ]
  13. Steinberg GR, Watt MJ, McGee SL, Chan S, Hargreaves M, Febbraio MA, Stapleton D, Kemp BE: Reduced glycogen availability is associated with increased AMPKalpha2 activity, nuclear AMPKalpha2 protein abundance, and GLUT4 mRNA expression in contracting human skeletal muscle. Appl Physiol Nutr Metab. 2006 Jun;31(3):302-12. [PubMed:16770359 ]
  14. Hudson ER, Pan DA, James J, Lucocq JM, Hawley SA, Green KA, Baba O, Terashima T, Hardie DG: A novel domain in AMP-activated protein kinase causes glycogen storage bodies similar to those seen in hereditary cardiac arrhythmias. Curr Biol. 2003 May 13;13(10):861-6. [PubMed:12747836 ]
  15. van Loon LJ, Murphy R, Oosterlaar AM, Cameron-Smith D, Hargreaves M, Wagenmakers AJ, Snow R: Creatine supplementation increases glycogen storage but not GLUT-4 expression in human skeletal muscle. Clin Sci (Lond). 2004 Jan;106(1):99-106. [PubMed:14507259 ]
  16. Tomihira M, Kawasaki E, Nakajima H, Imamura Y, Sato Y, Sata M, Kage M, Sugie H, Nunoi K: Intermittent and recurrent hepatomegaly due to glycogen storage in a patient with type 1 diabetes: genetic analysis of the liver glycogen phosphorylase gene (PYGL). Diabetes Res Clin Pract. 2004 Aug;65(2):175-82. [PubMed:15223230 ]
  17. McVie-Wylie AJ, Ding EY, Lawson T, Serra D, Migone FK, Pressley D, Mizutani M, Kikuchi T, Chen YT, Amalfitano A: Multiple muscles in the AMD quail can be "cross-corrected" of pathologic glycogen accumulation after intravenous injection of an [E1-, polymerase-] adenovirus vector encoding human acid-alpha-glucosidase. J Gene Med. 2003 May;5(5):399-406. [PubMed:12731088 ]
  18. Price TB, Laurent D, Petersen KF: 13C/31P NMR studies on the role of glucose transport/phosphorylation in human glycogen supercompensation. Int J Sports Med. 2003 May;24(4):238-44. [PubMed:12784164 ]
  19. Tanis AA, Rietveld T, Wattimena JL, van den Berg JW, Swart GR: The 13CO2 breath test for liver glycogen oxidation after 3-day labeling of the liver with a naturally 13C-enriched diet. Nutrition. 2003 May;19(5):432-7. [PubMed:12714096 ]
  20. Devries MC, Hamadeh MJ, Graham TE, Tarnopolsky MA: 17beta-estradiol supplementation decreases glucose rate of appearance and disappearance with no effect on glycogen utilization during moderate intensity exercise in men. J Clin Endocrinol Metab. 2005 Nov;90(11):6218-25. Epub 2005 Aug 23. [PubMed:16118338 ]