NP-MRD: Showing NP-Card for kebanmycin B (NP0333308)

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Record Information

Version

2.0

Created at

2024-05-28 16:57:12 UTC

Updated at

2025-12-20 07:41:06 UTC

NP-MRD ID

NP0333308

Natural Product DOI

https://doi.org/10.57994/2667

Secondary Accession Numbers

None

Natural Product Identification

Common Name

kebanmycin B

Description

Kebanmycin B belongs to the class of organic compounds known as diterpene lactones. These are diterpenoids containing a lactone moiety. Based on a literature review very few articles have been published on kebanmycin B.

Structure

MOL SDF PDB SMILES InChI


  Mrv2104 02092319332D          

 65 73  0  0  1  0            999 V2000
    6.6992   -4.6249    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.2075   -3.9624    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3879   -4.0571    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.5353   -3.2054    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0436   -2.5429    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3714   -1.7859    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1910   -1.6912    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.5188   -0.9342    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    7.0271   -0.2717    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.3383   -0.8395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.8301   -1.5020    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.5023   -2.2590    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.9940   -2.9215    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.6662   -3.6785    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.8135   -2.8268    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.1414   -2.0698    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.9609   -1.9751    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.4526   -2.6376    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   12.2722   -2.5429    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   12.7639   -3.2054    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   12.4361   -3.9624    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   12.9278   -4.6249    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   13.7474   -4.5302    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   14.0752   -3.7732    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   14.2391   -5.1927    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   15.0587   -5.0980    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   15.5504   -5.7605    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   15.3865   -4.3410    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   14.8948   -3.6785    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   15.2226   -2.9215    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   16.2061   -4.2463    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   16.6978   -4.9088    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   17.5174   -4.8141    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   18.0091   -5.4766    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   18.8286   -5.3819    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   17.6813   -6.2337    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   18.1730   -6.8961    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   17.8452   -7.6532    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   18.3369   -8.3156    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   17.0256   -7.7478    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   16.6978   -8.5049    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   15.8782   -8.5995    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   17.1895   -9.1673    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   18.0091   -9.0727    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   18.5008   -9.7351    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   16.8617   -9.9244    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   16.8617   -6.3283    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   16.3700   -5.6658    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   16.5339   -7.0854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.6166   -4.0571    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.2887   -4.8141    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.1248   -3.3946    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.3053   -3.4893    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.9775   -4.2463    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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    9.4857    0.0122    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.6827   -2.3537    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.3549   -3.1107    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8466   -3.7732    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.2240   -2.6376    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8962   -3.3946    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.0767   -3.4893    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5849   -2.8268    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7654   -2.9215    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  2  4  1  0  0  0  0
  4  5  2  0  0  0  0
  5  6  1  0  0  0  0
  6  7  2  0  0  0  0
  8  7  1  0  0  0  0
  8  9  1  6  0  0  0
  8 10  1  0  0  0  0
 10 11  1  0  0  0  0
 11 12  2  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 13 15  2  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 19 20  2  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 23 22  1  1  0  0  0
 23 24  1  0  0  0  0
 23 25  1  0  0  0  0
 26 25  1  0  0  0  0
 26 27  1  1  0  0  0
 28 26  1  0  0  0  0
 28 29  1  0  0  0  0
 29 24  1  0  0  0  0
 29 30  1  6  0  0  0
 28 31  1  6  0  0  0
 32 31  1  1  0  0  0
 32 33  1  0  0  0  0
 33 34  1  0  0  0  0
 34 35  1  0  0  0  0
 36 34  1  0  0  0  0
 36 37  1  6  0  0  0
 38 37  1  1  0  0  0
 38 39  1  0  0  0  0
 38 40  1  0  0  0  0
 41 40  1  0  0  0  0
 41 42  1  1  0  0  0
 43 41  1  0  0  0  0
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 43 46  1  6  0  0  0
 36 47  1  0  0  0  0
 47 48  1  0  0  0  0
 32 48  1  0  0  0  0
 47 49  1  1  0  0  0
 21 50  2  0  0  0  0
 50 51  1  0  0  0  0
 18 52  2  0  0  0  0
 50 52  1  0  0  0  0
 52 53  1  0  0  0  0
 15 53  1  0  0  0  0
 53 54  2  0  0  0  0
 16 55  2  0  0  0  0
 11 55  1  0  0  0  0
 55 56  1  0  0  0  0
 56 57  1  0  0  0  0
  7 58  1  0  0  0  0
 12 58  1  0  0  0  0
 58 59  2  0  0  0  0
  4 59  1  0  0  0  0
 59 60  1  0  0  0  0
  5 61  1  0  0  0  0
 62 61  1  0  0  0  0
 62  3  1  0  0  0  0
 62 63  1  6  0  0  0
 63 64  1  0  0  0  0
 64 65  1  0  0  0  0
M  END


  Mrv2104 02092319332D          

 65 73  0  0  1  0            999 V2000
    6.6992   -4.6249    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.2075   -3.9624    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3879   -4.0571    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.5353   -3.2054    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0436   -2.5429    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3714   -1.7859    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1910   -1.6912    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.5188   -0.9342    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    7.0271   -0.2717    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.3383   -0.8395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.8301   -1.5020    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.5023   -2.2590    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.9940   -2.9215    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.6662   -3.6785    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.8135   -2.8268    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.1414   -2.0698    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.9609   -1.9751    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.4526   -2.6376    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   12.2722   -2.5429    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
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   16.2061   -4.2463    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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   16.5339   -7.0854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.6166   -4.0571    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.2887   -4.8141    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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    9.4857    0.0122    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
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  1  2  2  0  0  0  0
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  8  9  1  6  0  0  0
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  7 58  1  0  0  0  0
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 58 59  2  0  0  0  0
  4 59  1  0  0  0  0
 59 60  1  0  0  0  0
  5 61  1  0  0  0  0
 62 61  1  0  0  0  0
 62  3  1  0  0  0  0
 62 63  1  6  0  0  0
 63 64  1  0  0  0  0
 64 65  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0333308

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CCC[C@@H]1CC2=C(C(=O)O1)C(O)=C1C(=C2)[C@H](O)CC2=C1C(O)=C1C(=O)C3=C(OC1=C2OC)C=CC(O[C@H]1C[C@H](O)[C@H](O[C@H]2CC(O)[C@H](O[C@H]4C[C@@H](O)[C@H](O)[C@@H](C)O4)[C@@H](C)O2)[C@@H](C)O1)=C3O

> <INCHI_IDENTIFIER>
InChI=1S/C46H54O19/c1-6-7-20-10-19-11-21-23(47)12-22-34(33(21)39(53)32(19)46(56)61-20)40(54)36-41(55)35-27(63-45(36)44(22)57-5)8-9-28(38(35)52)62-29-14-25(49)42(17(3)59-29)65-31-15-26(50)43(18(4)60-31)64-30-13-24(48)37(51)16(2)58-30/h8-9,11,16-18,20,23-26,29-31,37,42-43,47-54H,6-7,10,12-15H2,1-5H3/t16-,17-,18-,20-,23-,24-,25+,26?,29+,30+,31+,37-,42-,43-/m1/s1

> <INCHI_KEY>
PQXJTPXFBMCGAD-LMDFVCEKSA-N

> <FORMULA>
C46H54O19

> <MOLECULAR_WEIGHT>
910.919

> <EXACT_MASS>
910.325929519

> <JCHEM_ACCEPTOR_COUNT>
17

> <JCHEM_ATOM_COUNT>
119

> <JCHEM_AVERAGE_POLARIZABILITY>
95.50962256450194

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
8

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(3R,6R)-12-{[(2S,4S,5S,6R)-5-{[(2S,5S,6R)-5-{[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-6,13,15,16-tetrahydroxy-8-methoxy-3-propyl-1,3,4,6,7,14-hexahydro-2,9-dioxahexaphene-1,14-dione

> <JCHEM_LOGP>
5.777175098333331

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
9

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
8.901957098774822

> <JCHEM_PKA_STRONGEST_ACIDIC>
8.15054486520545

> <JCHEM_PKA_STRONGEST_BASIC>
-3.1490882934747897

> <JCHEM_POLAR_SURFACE_AREA>
279.04999999999995

> <JCHEM_REFRACTIVITY>
222.82150000000007

> <JCHEM_ROTATABLE_BOND_COUNT>
9

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
(3R,6R)-12-{[(2S,4S,5S,6R)-5-{[(2S,5S,6R)-5-{[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-6,13,15,16-tetrahydroxy-8-methoxy-3-propyl-3,4,6,7-tetrahydro-2,9-dioxahexaphene-1,14-dione

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 09-FEB-23   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   09-FEB-23         0                                  
HETATM    1  O   UNK     0      12.505  -8.633   0.000  0.00  0.00           O+0
HETATM    2  C   UNK     0      11.587  -7.397   0.000  0.00  0.00           C+0
HETATM    3  O   UNK     0      10.057  -7.573   0.000  0.00  0.00           O+0
HETATM    4  C   UNK     0      12.199  -5.983   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      11.281  -4.747   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      11.893  -3.334   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      13.423  -3.157   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      14.035  -1.744   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0      13.117  -0.507   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0      15.565  -1.567   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0      16.483  -2.804   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0      15.871  -4.217   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      16.789  -5.453   0.000  0.00  0.00           C+0
HETATM   14  O   UNK     0      16.177  -6.867   0.000  0.00  0.00           O+0
HETATM   15  C   UNK     0      18.319  -5.277   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0      18.931  -3.864   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0      20.460  -3.687   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0      21.378  -4.923   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      22.908  -4.747   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      23.826  -5.983   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      23.214  -7.397   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0      24.132  -8.633   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0      25.662  -8.456   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      26.274  -7.043   0.000  0.00  0.00           C+0
HETATM   25  O   UNK     0      26.580  -9.693   0.000  0.00  0.00           O+0
HETATM   26  C   UNK     0      28.110  -9.516   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0      29.027 -10.753   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0      28.721  -8.103   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0      27.804  -6.867   0.000  0.00  0.00           C+0
HETATM   30  O   UNK     0      28.416  -5.453   0.000  0.00  0.00           O+0
HETATM   31  O   UNK     0      30.251  -7.927   0.000  0.00  0.00           O+0
HETATM   32  C   UNK     0      31.169  -9.163   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0      32.699  -8.986   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0      33.617 -10.223   0.000  0.00  0.00           C+0
HETATM   35  O   UNK     0      35.147 -10.046   0.000  0.00  0.00           O+0
HETATM   36  C   UNK     0      33.005 -11.636   0.000  0.00  0.00           C+0
HETATM   37  O   UNK     0      33.923 -12.873   0.000  0.00  0.00           O+0
HETATM   38  C   UNK     0      33.311 -14.286   0.000  0.00  0.00           C+0
HETATM   39  C   UNK     0      34.229 -15.522   0.000  0.00  0.00           C+0
HETATM   40  O   UNK     0      31.781 -14.463   0.000  0.00  0.00           O+0
HETATM   41  C   UNK     0      31.169 -15.876   0.000  0.00  0.00           C+0
HETATM   42  C   UNK     0      29.639 -16.052   0.000  0.00  0.00           C+0
HETATM   43  C   UNK     0      32.087 -17.112   0.000  0.00  0.00           C+0
HETATM   44  C   UNK     0      33.617 -16.936   0.000  0.00  0.00           C+0
HETATM   45  O   UNK     0      34.535 -18.172   0.000  0.00  0.00           O+0
HETATM   46  O   UNK     0      31.475 -18.526   0.000  0.00  0.00           O+0
HETATM   47  C   UNK     0      31.475 -11.813   0.000  0.00  0.00           C+0
HETATM   48  O   UNK     0      30.557 -10.576   0.000  0.00  0.00           O+0
HETATM   49  C   UNK     0      30.863 -13.226   0.000  0.00  0.00           C+0
HETATM   50  C   UNK     0      21.684  -7.573   0.000  0.00  0.00           C+0
HETATM   51  O   UNK     0      21.072  -8.986   0.000  0.00  0.00           O+0
HETATM   52  C   UNK     0      20.766  -6.337   0.000  0.00  0.00           C+0
HETATM   53  C   UNK     0      19.237  -6.513   0.000  0.00  0.00           C+0
HETATM   54  O   UNK     0      18.625  -7.927   0.000  0.00  0.00           O+0
HETATM   55  C   UNK     0      18.013  -2.627   0.000  0.00  0.00           C+0
HETATM   56  O   UNK     0      18.625  -1.214   0.000  0.00  0.00           O+0
HETATM   57  C   UNK     0      17.707   0.023   0.000  0.00  0.00           C+0
HETATM   58  C   UNK     0      14.341  -4.393   0.000  0.00  0.00           C+0
HETATM   59  C   UNK     0      13.729  -5.807   0.000  0.00  0.00           C+0
HETATM   60  O   UNK     0      14.647  -7.043   0.000  0.00  0.00           O+0
HETATM   61  C   UNK     0       9.752  -4.923   0.000  0.00  0.00           C+0
HETATM   62  C   UNK     0       9.140  -6.337   0.000  0.00  0.00           C+0
HETATM   63  C   UNK     0       7.610  -6.513   0.000  0.00  0.00           C+0
HETATM   64  C   UNK     0       6.692  -5.277   0.000  0.00  0.00           C+0
HETATM   65  C   UNK     0       5.162  -5.453   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3    4                                                  
CONECT    3    2   62                                                       
CONECT    4    2    5   59                                                  
CONECT    5    4    6   61                                                  
CONECT    6    5    7                                                       
CONECT    7    6    8   58                                                  
CONECT    8    7    9   10                                                  
CONECT    9    8                                                            
CONECT   10    8   11                                                       
CONECT   11   10   12   55                                                  
CONECT   12   11   13   58                                                  
CONECT   13   12   14   15                                                  
CONECT   14   13                                                            
CONECT   15   13   16   53                                                  
CONECT   16   15   17   55                                                  
CONECT   17   16   18                                                       
CONECT   18   17   19   52                                                  
CONECT   19   18   20                                                       
CONECT   20   19   21                                                       
CONECT   21   20   22   50                                                  
CONECT   22   21   23                                                       
CONECT   23   22   24   25                                                  
CONECT   24   23   29                                                       
CONECT   25   23   26                                                       
CONECT   26   25   27   28                                                  
CONECT   27   26                                                            
CONECT   28   26   29   31                                                  
CONECT   29   28   24   30                                                  
CONECT   30   29                                                            
CONECT   31   28   32                                                       
CONECT   32   31   33   48                                                  
CONECT   33   32   34                                                       
CONECT   34   33   35   36                                                  
CONECT   35   34                                                            
CONECT   36   34   37   47                                                  
CONECT   37   36   38                                                       
CONECT   38   37   39   40                                                  
CONECT   39   38   44                                                       
CONECT   40   38   41                                                       
CONECT   41   40   42   43                                                  
CONECT   42   41                                                            
CONECT   43   41   44   46                                                  
CONECT   44   43   39   45                                                  
CONECT   45   44                                                            
CONECT   46   43                                                            
CONECT   47   36   48   49                                                  
CONECT   48   47   32                                                       
CONECT   49   47                                                            
CONECT   50   21   51   52                                                  
CONECT   51   50                                                            
CONECT   52   18   50   53                                                  
CONECT   53   52   15   54                                                  
CONECT   54   53                                                            
CONECT   55   16   11   56                                                  
CONECT   56   55   57                                                       
CONECT   57   56                                                            
CONECT   58    7   12   59                                                  
CONECT   59   58    4   60                                                  
CONECT   60   59                                                            
CONECT   61    5   62                                                       
CONECT   62   61    3   63                                                  
CONECT   63   62   64                                                       
CONECT   64   63   65                                                       
CONECT   65   64                                                            
MASTER        0    0    0    0    0    0    0    0   65    0  146    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₄₆H₅₄O₁₉

Average Mass

910.9190 Da

Monoisotopic Mass

910.32593 Da

IUPAC Name

(3R,6R)-12-{[(2S,4S,5S,6R)-5-{[(2S,5S,6R)-5-{[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-6,13,15,16-tetrahydroxy-8-methoxy-3-propyl-1,3,4,6,7,14-hexahydro-2,9-dioxahexaphene-1,14-dione

Traditional Name

CAS Registry Number

Not Available

SMILES

CCC[C@@H]1CC2=C(C(=O)O1)C(O)=C1C(=C2)[C@H](O)CC2=C1C(O)=C1C(=O)C3=C(OC1=C2OC)C=CC(O[C@H]1C[C@H](O)[C@H](O[C@H]2CC(O)[C@H](O[C@H]4C[C@@H](O)[C@H](O)[C@@H](C)O4)[C@@H](C)O2)[C@@H](C)O1)=C3O

InChI Identifier

InChI=1S/C46H54O19/c1-6-7-20-10-19-11-21-23(47)12-22-34(33(21)39(53)32(19)46(56)61-20)40(54)36-41(55)35-27(63-45(36)44(22)57-5)8-9-28(38(35)52)62-29-14-25(49)42(17(3)59-29)65-31-15-26(50)43(18(4)60-31)64-30-13-24(48)37(51)16(2)58-30/h8-9,11,16-18,20,23-26,29-31,37,42-43,47-54H,6-7,10,12-15H2,1-5H3/t16-,17-,18-,20-,23-,24-,25+,26?,29+,30+,31+,37-,42-,43-/m1/s1

InChI Key

PQXJTPXFBMCGAD-LMDFVCEKSA-N

Experimental Spectra

Spectrum Type	Description	Depositor Email	Depositor Organization	Depositor	Deposition Date	View
HSQC NMR	[¹H, ¹³C] NMR Spectrum (2D, 700 MHz, C2D6OS, experimental)	wzhang@scsio.ac.cn	South China Sea Institute of Oceanology, CAS	Wenjun Zhang	2024-05-28	View Spectrum
NOESY NMR	[¹H, ¹H] NMR Spectrum (2D, 700 MHz, C2D6OS, experimental)	wzhang@scsio.ac.cn	South China Sea Institute of Oceanology, CAS	Wenjun Zhang	2024-05-28	View Spectrum
HMBC NMR	[¹H, ¹³C] NMR Spectrum (2D, 700 MHz, C2D6OS, experimental)	wzhang@scsio.ac.cn	South China Sea Institute of Oceanology, CAS	Wenjun Zhang	2024-05-28	View Spectrum
COSY NMR	[¹H, ¹H] NMR Spectrum (2D, 700 MHz, C2D6OS, experimental)	wzhang@scsio.ac.cn	South China Sea Institute of Oceanology, CAS	Wenjun Zhang	2024-05-28	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, C2D6OS, experimental)	wzhang@scsio.ac.cn	South China Sea Institute of Oceanology, CAS	Wenjun Zhang	2024-05-28	View Spectrum
1D_DEPT NMR	¹³C NMR Spectrum (1D, 176 MHz, C2D6OS, experimental)	wzhang@scsio.ac.cn	South China Sea Institute of Oceanology, CAS	Wenjun Zhang	2024-05-28	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, C2D6OS, experimental)	wzhang@scsio.ac.cn	South China Sea Institute of Oceanology, CAS	Wenjun Zhang	2024-05-28	View Spectrum

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Streptomyces SCSIO 40068		Not Available

Chemical Taxonomy

Description

This compound belongs to the class of organic compounds known as diterpene lactones. These are diterpenoids containing a lactone moiety.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Terpene lactones

Direct Parent

Diterpene lactones

Alternative Parents

Substituents

Diterpenoid
Diterpene lactone
Xanthone
Naphthopyranone
Xanthene
Phenanthrene
Naphthopyran
Dibenzopyran
Fatty alcohol ester
Chromone
2-benzopyran
1-benzopyran
Naphthalene
Isochromane
Benzopyran
Anisole
1-hydroxy-4-unsubstituted benzenoid
Pyranone
Fatty acid ester
Dihydropyranone
Alkyl aryl ether
Fatty acyl
Alpha-branched alpha,beta-unsaturated-ketone
Benzenoid
Pyran
Oxane
Monosaccharide
Beta-hydroxy ketone
Heteroaromatic compound
Vinylogous acid
Alpha,beta-unsaturated ketone
Alpha,beta-unsaturated carboxylic ester
Enoate ester
Enone
Acryloyl-group
Secondary alcohol
Lactone
Ketone
Carboxylic acid ester
Oxacycle
Organoheterocyclic compound
Monocarboxylic acid or derivatives
Ether
Carboxylic acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Alcohol
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	5.78	ChemAxon
pKa (Strongest Acidic)	8.15	ChemAxon
pKa (Strongest Basic)	-3.1	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	17	ChemAxon
Hydrogen Donor Count	8	ChemAxon
Polar Surface Area	279.05 Å²	ChemAxon
Rotatable Bond Count	9	ChemAxon
Refractivity	222.82 m³·mol⁻¹	ChemAxon
Polarizability	95.51 Å³	ChemAxon
Number of Rings	9	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

Not Available

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Showing NP-Card for kebanmycin B (NP0333308)

MOL for NP0333308 (kebanmycin B)

3D MOL for NP0333308 (kebanmycin B)

3D SDF for NP0333308 (kebanmycin B)

3D-SDF for NP0333308 (kebanmycin B)

PDB for NP0333308 (kebanmycin B)

3D PDB for NP0333308 (kebanmycin B)

SMILES for NP0333308 (kebanmycin B)

INCHI for NP0333308 (kebanmycin B)

Structure for NP0333308 (kebanmycin B)

3D Structure for NP0333308 (kebanmycin B)