NP-MRD: Showing NP-Card for (+)-2-Dehydro-3-epi-20-hydroxyecdysone (NP0077462)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-04-28 22:36:42 UTC

Updated at

2022-04-28 22:36:42 UTC

NP-MRD ID

NP0077462

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(+)-2-Dehydro-3-epi-20-hydroxyecdysone

Description

(22R)-3alpha,14,20,22,25-Pentahydroxy-5beta-cholest-7-ene-2,6-dione belongs to the class of organic compounds known as pentahydroxy bile acids, alcohols and derivatives. These are bile acids, alcohols or derivatives bearing five hydroxyl groups. (+)-2-Dehydro-3-epi-20-hydroxyecdysone is found in Froelichia floridana. Based on a literature review very few articles have been published on (22R)-3alpha,14,20,22,25-Pentahydroxy-5beta-cholest-7-ene-2,6-dione.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652304292200362D          

 34 37  0  0  1  0            999 V2000
    4.2475    2.1537    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7793    2.7844    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.5278    1.3777    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.9960    0.7470    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1838    0.8922    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.9035    1.6682    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.4354    2.2989    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0914    1.8134    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.5596    1.1827    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8399    0.4067    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6520    0.2615    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9323   -0.5144    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7475    1.3279    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.4672    2.1038    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.9990    2.7345    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8111    2.5893    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3574    2.0770    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.5867    1.2845    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0962    0.8215    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8637    2.7283    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.3701    3.3797    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.0592    4.1438    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1873    3.2668    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6937    3.9181    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5109    3.8053    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3282    3.6924    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3981    2.9880    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6238    4.6225    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5151    2.2220    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2124    3.2347    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1073    2.8462    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9451    0.5269    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6232    2.4441    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3399    1.2325    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  1  3  1  0  0  0  0
  3  4  1  0  0  0  0
  5  4  1  1  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  1  7  1  0  0  0  0
  6  8  1  0  0  0  0
  8  9  1  6  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
  5 11  1  0  0  0  0
 11 12  2  0  0  0  0
  9 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
  8 16  1  0  0  0  0
 14 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 13 19  1  0  0  0  0
 17 20  1  6  0  0  0
 20 21  1  0  0  0  0
 21 22  1  1  0  0  0
 21 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  1  0  0  0  0
 25 26  1  0  0  0  0
 25 27  1  0  0  0  0
 25 28  1  0  0  0  0
 20 29  1  6  0  0  0
 20 30  1  6  0  0  0
 14 31  1  6  0  0  0
 13 32  1  1  0  0  0
  6 33  1  6  0  0  0
  3 34  1  1  0  0  0
M  END

     RDKit          3D

 76 79  0  0  0  0  0  0  0  0999 V2000
   -5.1352    2.2812    0.1857 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9335    0.9947    0.2371 C   0  0  2  0  0  0  0  0  0  0  0  0
   -7.3873    1.4302   -0.0543 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8716    0.4694    1.5087 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5627    0.0701   -0.8671 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1506   -0.3805   -0.9332 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6865   -1.1231    0.2696 C   0  0  1  0  0  0  0  0  0  0  0  0
   -4.5149   -2.2501    0.4052 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2263   -1.5814    0.1380 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.0704   -2.5587   -0.9749 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9968   -2.2937    1.3409 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3610   -0.3857    0.0985 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.5787    0.3844    1.4021 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2138    0.9619    1.7916 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5903    0.7261    0.5765 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.2765    1.6725   -0.3984 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.0506    0.6406    0.7508 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6869    0.8028    1.8665 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1408    0.6931    1.9069 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7927    0.7877    2.9657 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.9291    0.4571    0.6499 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.4959    1.7376    0.0872 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.6568    1.3413   -0.8338 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.9584    2.3371   -1.7369 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.2729    0.0571   -1.4787 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1508   -0.7233   -1.8180 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8221   -0.2122   -1.6786 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1001   -0.3201   -0.3471 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.0446   -1.7793    0.0282 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7864    0.3512   -0.4986 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.9064   -0.2515   -1.5593 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7473   -1.0391   -1.1136 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1170   -0.6573    0.1715 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.5115   -1.6065    1.2547 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5803    2.3753   -0.7767 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3799    2.2547    0.9988 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7820    3.1654    0.3473 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.3981    1.9415   -1.0584 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.7720    2.0861    0.7262 H   0  0  0  0  0  0  0  0  0  0  0  0
   -8.0268    0.5349   -0.1745 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5667    1.1354    2.1769 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7823    0.6277   -1.8264 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.2630   -0.8079   -0.9222 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0712   -0.9999   -1.8766 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4930    0.5035   -1.0866 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8239   -0.5065    1.1622 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3748   -2.6907    1.2767 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1515   -2.1140   -1.9829 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9111   -3.3066   -0.8593 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1522   -3.1517   -0.8141 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0348   -3.2534    1.2004 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5261    0.2308   -0.7889 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2114    1.2518    1.1391 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9852   -0.2539    2.1904 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1551    0.5191    2.7252 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2997    2.0688    2.0012 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.4180    2.5600    0.0136 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1180    1.0241    2.7782 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.8038   -0.1860    0.9082 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.9250    2.3180    0.9298 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.7967    2.3322   -0.5053 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.5397    1.1665   -0.1673 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.8835    2.6936   -1.5636 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.3732    0.5604   -2.3190 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.7563   -1.1765   -2.2412 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.0779   -2.2137   -0.1320 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.9012   -1.8425    1.1265 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2856   -2.3174   -0.5336 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.0450    1.3886   -0.8935 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5833    0.5115   -2.3118 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.5831   -0.9327   -2.1581 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.9893   -2.1214   -1.1066 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0568   -0.9561   -1.9061 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0180   -1.4457    2.2161 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5890   -1.3726    1.5026 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.4887   -2.6345    0.8904 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  2  4  1  1
  2  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  7  9  1  0
  9 10  1  0
  9 11  1  1
  9 12  1  0
 12 13  1  0
 13 14  1  0
 14 15  1  0
 15 16  1  6
 15 17  1  0
 17 18  2  0
 18 19  1  0
 19 20  2  0
 19 21  1  0
 21 22  1  0
 22 23  1  0
 23 24  1  0
 23 25  1  0
 25 26  2  0
 25 27  1  0
 27 28  1  0
 28 29  1  1
 28 30  1  0
 30 31  1  0
 31 32  1  0
 32 33  1  0
 33 34  1  1
 33 12  1  0
 33 15  1  0
 30 17  1  0
 28 21  1  0
  1 35  1  0
  1 36  1  0
  1 37  1  0
  3 38  1  0
  3 39  1  0
  3 40  1  0
  4 41  1  0
  5 42  1  0
  5 43  1  0
  6 44  1  0
  6 45  1  0
  7 46  1  1
  8 47  1  0
 10 48  1  0
 10 49  1  0
 10 50  1  0
 11 51  1  0
 12 52  1  6
 13 53  1  0
 13 54  1  0
 14 55  1  0
 14 56  1  0
 16 57  1  0
 18 58  1  0
 21 59  1  1
 22 60  1  0
 22 61  1  0
 23 62  1  1
 24 63  1  0
 27 64  1  0
 27 65  1  0
 29 66  1  0
 29 67  1  0
 29 68  1  0
 30 69  1  6
 31 70  1  0
 31 71  1  0
 32 72  1  0
 32 73  1  0
 34 74  1  0
 34 75  1  0
 34 76  1  0
M  END


  Mrv1652304292200362D          

 34 37  0  0  1  0            999 V2000
    4.2475    2.1537    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7793    2.7844    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.5278    1.3777    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.9960    0.7470    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1838    0.8922    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.9035    1.6682    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.4354    2.2989    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0914    1.8134    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.5596    1.1827    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8399    0.4067    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6520    0.2615    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9323   -0.5144    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7475    1.3279    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.4672    2.1038    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.9990    2.7345    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8111    2.5893    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3574    2.0770    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.5867    1.2845    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0962    0.8215    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8637    2.7283    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.3701    3.3797    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.0592    4.1438    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1873    3.2668    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6937    3.9181    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5109    3.8053    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3282    3.6924    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3981    2.9880    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6238    4.6225    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5151    2.2220    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2124    3.2347    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1073    2.8462    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9451    0.5269    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6232    2.4441    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3399    1.2325    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  1  3  1  0  0  0  0
  3  4  1  0  0  0  0
  5  4  1  1  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  1  7  1  0  0  0  0
  6  8  1  0  0  0  0
  8  9  1  6  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
  5 11  1  0  0  0  0
 11 12  2  0  0  0  0
  9 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
  8 16  1  0  0  0  0
 14 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 13 19  1  0  0  0  0
 17 20  1  6  0  0  0
 20 21  1  0  0  0  0
 21 22  1  1  0  0  0
 21 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  1  0  0  0  0
 25 26  1  0  0  0  0
 25 27  1  0  0  0  0
 25 28  1  0  0  0  0
 20 29  1  6  0  0  0
 20 30  1  6  0  0  0
 14 31  1  6  0  0  0
 13 32  1  1  0  0  0
  6 33  1  6  0  0  0
  3 34  1  1  0  0  0
M  END
> <DATABASE_ID>
NP0077462

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(C)(O)CC[C@@H](O)[C@](C)(O)[C@H]1CC[C@@]2(O)C3=CC(=O)[C@@H]4C[C@H](O)C(=O)C[C@]4(C)[C@H]3CC[C@]12C

> <INCHI_IDENTIFIER>
InChI=1S/C27H42O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19,21-22,29,31-34H,6-11,13-14H2,1-5H3/t15-,17-,19-,21-,22+,24+,25+,26+,27+/m0/s1

> <INCHI_KEY>
RRGYPIOLUPMGCP-FJWASMFLSA-N

> <FORMULA>
C27H42O7

> <MOLECULAR_WEIGHT>
478.626

> <EXACT_MASS>
478.293053692

> <JCHEM_ACCEPTOR_COUNT>
7

> <JCHEM_ATOM_COUNT>
76

> <JCHEM_AVERAGE_POLARIZABILITY>
52.76593996311382

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
5

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(1R,2R,5S,7R,11S,14S,15R)-5,11-dihydroxy-2,15-dimethyl-14-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-9-ene-4,8-dione

> <ALOGPS_LOGP>
1.74

> <JCHEM_LOGP>
1.0212006926666697

> <ALOGPS_LOGS>
-3.27

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
13.578400168305944

> <JCHEM_PKA_STRONGEST_ACIDIC>
13.07708670251995

> <JCHEM_PKA_STRONGEST_BASIC>
-2.627423734269491

> <JCHEM_POLAR_SURFACE_AREA>
135.29000000000002

> <JCHEM_REFRACTIVITY>
127.97839999999994

> <JCHEM_ROTATABLE_BOND_COUNT>
5

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
2.56e-01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(1R,2R,5S,7R,11S,14S,15R)-5,11-dihydroxy-2,15-dimethyl-14-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-9-ene-4,8-dione

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 29-APR-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   29-APR-22         0                                  
HETATM    1  C   UNK     0       7.929   4.020   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0       8.921   5.197   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0       8.452   2.572   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       7.459   1.394   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       5.943   1.666   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       5.420   3.114   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       6.413   4.291   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       3.904   3.385   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       2.911   2.208   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       3.434   0.759   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       4.950   0.488   0.000  0.00  0.00           C+0
HETATM   12  O   UNK     0       5.474  -0.960   0.000  0.00  0.00           O+0
HETATM   13  C   UNK     0       1.395   2.479   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       0.872   3.927   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       1.865   5.104   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       3.381   4.833   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0      -0.667   3.877   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      -1.095   2.398   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       0.179   1.534   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      -1.612   5.093   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      -2.557   6.309   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0      -1.977   7.735   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0      -4.083   6.098   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      -5.028   7.314   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0      -6.554   7.103   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0      -8.079   6.893   0.000  0.00  0.00           C+0
HETATM   27  O   UNK     0      -6.343   5.578   0.000  0.00  0.00           O+0
HETATM   28  C   UNK     0      -6.764   8.629   0.000  0.00  0.00           C+0
HETATM   29  O   UNK     0      -2.828   4.148   0.000  0.00  0.00           O+0
HETATM   30  C   UNK     0      -0.396   6.038   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       0.200   5.313   0.000  0.00  0.00           C+0
HETATM   32  O   UNK     0       1.764   0.984   0.000  0.00  0.00           O+0
HETATM   33  C   UNK     0       4.897   4.562   0.000  0.00  0.00           C+0
HETATM   34  O   UNK     0       9.968   2.301   0.000  0.00  0.00           O+0
CONECT    1    2    3    7                                                  
CONECT    2    1                                                            
CONECT    3    1    4   34                                                  
CONECT    4    3    5                                                       
CONECT    5    4    6   11                                                  
CONECT    6    5    7    8   33                                             
CONECT    7    6    1                                                       
CONECT    8    6    9   16                                                  
CONECT    9    8   10   13                                                  
CONECT   10    9   11                                                       
CONECT   11   10    5   12                                                  
CONECT   12   11                                                            
CONECT   13    9   14   19   32                                             
CONECT   14   13   15   17   31                                             
CONECT   15   14   16                                                       
CONECT   16   15    8                                                       
CONECT   17   14   18   20                                                  
CONECT   18   17   19                                                       
CONECT   19   18   13                                                       
CONECT   20   17   21   29   30                                             
CONECT   21   20   22   23                                                  
CONECT   22   21                                                            
CONECT   23   21   24                                                       
CONECT   24   23   25                                                       
CONECT   25   24   26   27   28                                             
CONECT   26   25                                                            
CONECT   27   25                                                            
CONECT   28   25                                                            
CONECT   29   20                                                            
CONECT   30   20                                                            
CONECT   31   14                                                            
CONECT   32   13                                                            
CONECT   33    6                                                            
CONECT   34    3                                                            
MASTER        0    0    0    0    0    0    0    0   34    0   74    0
END

View in JSmol

Synonyms

Value	Source
(22R)-3a,14,20,22,25-Pentahydroxy-5b-cholest-7-ene-2,6-dione	Generator
(22R)-3Α,14,20,22,25-pentahydroxy-5β-cholest-7-ene-2,6-dione	Generator

Chemical Formula

C₂₇H₄₂O₇

Average Mass

478.6260 Da

Monoisotopic Mass

478.29305 Da

IUPAC Name

(1R,2R,5S,7R,11S,14S,15R)-5,11-dihydroxy-2,15-dimethyl-14-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-9-ene-4,8-dione

Traditional Name

(1R,2R,5S,7R,11S,14S,15R)-5,11-dihydroxy-2,15-dimethyl-14-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-9-ene-4,8-dione

CAS Registry Number

Not Available

SMILES

CC(C)(O)CC[C@@H](O)[C@](C)(O)[C@H]1CC[C@@]2(O)C3=CC(=O)[C@@H]4C[C@H](O)C(=O)C[C@]4(C)[C@H]3CC[C@]12C

InChI Identifier

InChI=1S/C27H42O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19,21-22,29,31-34H,6-11,13-14H2,1-5H3/t15-,17-,19-,21-,22+,24+,25+,26+,27+/m0/s1

InChI Key

RRGYPIOLUPMGCP-FJWASMFLSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Froelichia floridana	Plant	KNApSAcK

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as pentahydroxy bile acids, alcohols and derivatives. These are bile acids, alcohols or derivatives bearing five hydroxyl groups.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Steroids and steroid derivatives

Sub Class

Bile acids, alcohols and derivatives

Direct Parent

Pentahydroxy bile acids, alcohols and derivatives

Alternative Parents

Substituents

Pentahydroxy bile acid, alcohol, or derivatives
Cholesterol-skeleton
Cholesterol
Cholestane-skeleton
Ecdysteroid
25-hydroxysteroid
22-hydroxysteroid
20-hydroxysteroid
6-oxosteroid
3-alpha-hydroxysteroid
2-oxosteroid
Oxosteroid
Hydroxysteroid
14-hydroxysteroid
3-hydroxysteroid
3-hydroxy-delta-7-steroid
Delta-7-steroid
Cyclohexenone
Tertiary alcohol
Cyclic alcohol
Cyclic ketone
Secondary alcohol
Ketone
Polyol
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Alcohol
Aliphatic homopolycyclic compound

Molecular Framework

Aliphatic homopolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	1.74	ALOGPS
logP	1.02	ChemAxon
logS	-3.3	ALOGPS
pKa (Strongest Acidic)	13.08	ChemAxon
pKa (Strongest Basic)	-2.6	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	7	ChemAxon
Hydrogen Donor Count	5	ChemAxon
Polar Surface Area	135.29 Å²	ChemAxon
Rotatable Bond Count	5	ChemAxon
Refractivity	127.98 m³·mol⁻¹	ChemAxon
Polarizability	52.77 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

8966144

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

10790832

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Not Available

Showing NP-Card for (+)-2-Dehydro-3-epi-20-hydroxyecdysone (NP0077462)

MOL for NP0077462 ((+)-2-Dehydro-3-epi-20-hydroxyecdysone)

3D MOL for NP0077462 ((+)-2-Dehydro-3-epi-20-hydroxyecdysone)

3D SDF for NP0077462 ((+)-2-Dehydro-3-epi-20-hydroxyecdysone)

3D-SDF for NP0077462 ((+)-2-Dehydro-3-epi-20-hydroxyecdysone)

PDB for NP0077462 ((+)-2-Dehydro-3-epi-20-hydroxyecdysone)

3D PDB for NP0077462 ((+)-2-Dehydro-3-epi-20-hydroxyecdysone)

SMILES for NP0077462 ((+)-2-Dehydro-3-epi-20-hydroxyecdysone)

INCHI for NP0077462 ((+)-2-Dehydro-3-epi-20-hydroxyecdysone)

Structure for NP0077462 ((+)-2-Dehydro-3-epi-20-hydroxyecdysone)

3D Structure for NP0077462 ((+)-2-Dehydro-3-epi-20-hydroxyecdysone)